... (RXR-alpha), also known as NR2B1 (nuclear receptor subfamily 2, group B, member 1) is a nuclear ... "Entrez Gene: RXRA retinoid X receptor, alpha". "Retinoic acid receptor RXR-alpha - Homo sapiens (Human)". UniProt. Na SY, Choi ... Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of ... Kliewer SA, Umesono K, Mangelsdorf DJ, Evans RM (January 1992). "Retinoid X receptor interacts with nuclear receptors in ...
"Expression of retinoid-X receptors (-alpha,-beta,-gamma) and retinoic acid receptors (-alpha,-beta,-gamma) in normal human skin ... Retinoid X receptor Retinoid X receptor gamma has been shown to interact with ITGB3BP. GRCh38: Ensembl release 89: ... Retinoid X receptor gamma (RXR-gamma), also known as NR2B3 (nuclear receptor subfamily 2, group B, member 3) is a nuclear ... This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the ...
Jetten AM (2009). "Retinoid-related orphan receptors (RORs): critical roles in development, immunity, circadian rhythm, and ... RAR-related orphan receptor alpha (RORα), also known as NR1F1 (nuclear receptor subfamily 1, group F, member 1) is a nuclear ... "Retinoic-acid-receptor-related orphan nuclear receptor alpha is required for natural helper cell development and allergic ... Giguère V, Beatty B, Squire J, Copeland NG, Jenkins NA (August 1995). "The orphan nuclear receptor ROR alpha (RORA) maps to a ...
... has been shown to interact with Retinoid X receptor alpha. RING finger domain GRCh38: Ensembl release 89: ENSG00000112130 ... interacts with retinoid X receptor alpha and enhances its transcription-stimulating activity". The Journal of Biological ... interacts with retinoid X receptor alpha and enhances its transcription-stimulating activity". The Journal of Biological ...
Kooistra T, Lansink M, Arts J, Sitter T, Toet K (Sep 1995). "Involvement of retinoic acid receptor alpha in the stimulation of ... RXRB retinoid X receptor, beta". Szanto A, Narkar V, Shen Q, Uray IP, Davies PJ, Nagy L (Dec 2004). "Retinoid X receptors: X- ... Retinoid X receptor beta (RXR-beta), also known as NR2B2 (nuclear receptor subfamily 2, group B, member 2) is a nuclear ... This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the ...
Retinoic acid receptor alpha (RARα) and retinoid X receptor alpha (RXRα). In peripheral clocks, RARα and RXRα interact with ... "Regulation of CLOCK and MOP4 by nuclear hormone receptors in the vasculature: a humoral mechanism to reset a peripheral clock ... "Circadian clock control of hepatic metabolism via nuclear receptor SHP (579.3)". The FASEB Journal. 28 (1 Supplement): 579.3. ...
Retinoic acid receptor Retinoid X receptor alpha Retinoid X receptor beta Retinoid X receptor gamma Germain P, Chambon P, ... The retinoid X receptor (RXR) is a type of nuclear receptor that is activated by 9-cis retinoic acid, which is discussed ... "Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids". Proc Natl Acad Sci USA. 90 (1 ... Retinoid+X+Receptors at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e v t e (Articles with short ...
August 2012). "Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha". Nucleic Acids ...
August 2012). "Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha". Nucleic Acids ... The "Neh7" domain is involved in the repression of Nrf2 transcriptional activity by the retinoid X receptor α through a ... activates the NRF2 pathway and has been identified as a nicotinic acid receptor agonist in vitro. The label includes warnings ...
... has been shown to interact with NCOA6 and Retinoid X receptor alpha. GRCh38: Ensembl release 89: ... Like other receptors in the family, LXRs heterodimerize with retinoid X receptor and bind to specific response elements (LXREs ... Crystal structure of human liver X receptor β(LXRβ) forming heterodimer with its partner retinoid X receptor α(RXRα) on its ... "Structure of the retinoid X receptor α-liver X receptor β (RXRα-LXRβ) heterodimer on DNA". Nature Structural & Molecular ...
Retinoid receptor Giguère V, Tini M, Flock G, Ong E, Evans RM, Otulakowski G (March 1994). "Isoform-specific amino-terminal ... "Transcriptional activation of the nuclear receptor RZR alpha by the pineal gland hormone melatonin and identification of CGP ... Jetten AM, Joo JH (2006). "Retinoid-related Orphan Receptors (RORs): Roles in Cellular Differentiation and Development". ... The RAR-related orphan receptors (RORs) are members of the nuclear receptor family of intracellular transcription factors. ...
... subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate ... Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and ... January 2002). "Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor ... nuclear receptor subfamily 1, group C, member 3) is a type II nuclear receptor functioning as a transcription factor that in ...
... has been shown to interact with Thyroid hormone receptor beta and Retinoid X receptor alpha. GRCh38: Ensembl release 89: ... "p120 acts as a specific coactivator for 9-cis-retinoic acid receptor (RXR) on peroxisome proliferator-activated receptor-gamma/ ... "p120 acts as a specific coactivator for 9-cis-retinoic acid receptor (RXR) on peroxisome proliferator-activated receptor-gamma/ ... The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid ...
... and Retinoid X receptor alpha. ENSG00000282905 GRCh38: Ensembl release 89: ENSG00000104825, ENSG00000282905 - Ensembl, May 2017 ... "IkappaBbeta interacts with the retinoid X receptor and inhibits retinoid-dependent transactivation in lipopolysaccharide- ... "IkappaBbeta interacts with the retinoid X receptor and inhibits retinoid-dependent transactivation in lipopolysaccharide- ... Beauparlant P, Kwon H, Clarke M, Lin R, Sonenberg N, Wainberg M, Hiscott J (1996). "Transdominant mutants of I kappa B alpha ...
Zhang F, Meng F, Li H, Dong Y, Yang W, Han A (September 2011). "Suppression of retinoid X receptor alpha and aberrant β-catenin ... First of all, by binding to cadherin receptor intracellular cytoplasmic tail domains, it can act as an integral component of a ... Keratinocytes engineered to not express alpha-catenin have disrupted cell adhesion and activated NF-κB. A tumor cell line with ... Flores ER, Halder G (2011). "Stem cell proliferation in the skin: alpha-catenin takes over the hippo pathway". Sci Signal. 4 ( ...
... has been shown to interact with Mineralocorticoid receptor, TRIM33, Estrogen receptor alpha and Retinoid X receptor ... 1997). "TIF1 alpha: a chromatin-specific mediator for the ligand-dependent activation function AF-2 of nuclear receptors?". ... region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to ... Le Douarin B, Nielsen AL, You J, Chambon P, Losson R (May 1997). "TIF1 alpha: a chromatin-specific mediator for the ligand- ...
It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a ... Collagen alpha-2(XI) chain is a protein that in humans is encoded by the COL11A2 gene. The COL11A2 gene produces one component ... This mutation causes the amino acid glycine to be replaced with the amino acid glutamic acid at position 955 in the alpha 2 ... Hanson IM, Gorman P, Lui VC, Cheah KS, Solomon E, Trowsdale J (November 1989). "The human alpha 2(XI) collagen gene (COL11A2) ...
"Direct functional interactions between insulin-like growth factor-binding protein-3 and retinoid X receptor-alpha regulate ... low density lipoprotein receptor-related protein 1 (LRP1), also known as alpha-2-macroglobulin receptor or type V TGFβ receptor ... it can modulate nuclear hormone receptor activity by direct binding to retinoid X receptor, retinoic acid receptor, vitamin D ... Functional interactions with the EGF receptor and the type I/type II TGFβ receptor system have also been reported, and other ...
... specific ligands of the nuclear receptor retinoid Z receptor/retinoid acid receptor-related orphan receptor alpha with potent ... CGP 52608 is a selective ligand of the RAR-related orphan receptor alpha. It has been used as a biochemical tool to investigate ... "Transcriptional activation of the nuclear receptor RZR alpha by the pineal gland hormone melatonin and identification of CGP ... Winczyk, K; Pawlikowski, M; Karasek, M (Sep 2001). "Melatonin and RZR/ROR receptor ligand CGP 52608 induce apoptosis in the ...
This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular ... In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid ... Yu X, Li P, Roeder RG, Wang Z (2001). "Inhibition of androgen receptor-mediated transcription by amino-terminal enhancer of ... "A novel homeobox protein which recognizes a TGT core and functionally interferes with a retinoid-responsive motif". J Biol Chem ...
... of apoptotic cells in mice with macrophage peroxisome proliferator-activated receptor gamma or retinoid X receptor alpha ... Non-opsonic receptors include lectin-type receptors, Dectin receptor, or scavenger receptors. Some phagocytic pathways require ... Macrophages initiate phagocytosis by mannose receptors, scavenger receptors, Fcγ receptors and complement receptors 1, 3 and 4 ... The ingestion mediated by the mannose receptor is distinct in molecular mechanisms from Fcγ receptor or complement receptor ...
... of apoptotic cells in mice with macrophage peroxisome proliferator-activated receptor gamma or retinoid X receptor alpha ... With vitamin D present, vitamin D response elements (VDRE) are encoded and expressed via pattern recognition receptors (PRR) ...
... has been shown to interact with: Retinoic acid receptor alpha, Retinoid X receptor alpha, TADA2L, TAF9, Transcription ... "ADA3-containing complexes associate with estrogen receptor alpha". Nucleic Acids Research. 30 (11): 2508-14. doi:10.1093/nar/ ... "Human ADA3 binds to estrogen receptor (ER) and functions as a coactivator for ER-mediated transactivation". The Journal of ... "Human papilloma virus 16 E6 oncoprotein inhibits retinoic X receptor-mediated transactivation by targeting human ADA3 ...
... and its metabolites have been reported to bind to and/or activate the transcription factors PPAR-alpha and retinoid X receptor ... "Phytol metabolites are circulating dietary factors that activate the nuclear receptor RXR". Molecular Biology of the Cell. 7 (8 ...
... its metabolites have been reported to bind to and/or activate the transcription factors PPAR-alpha and retinoid X receptor (RXR ... "Phytol metabolites are circulating dietary factors that activate the nuclear receptor RXR". Molecular Biology of the Cell. 7 (8 ...
... a novel coactivator of the retinoid X receptor alpha pathway". The Journal of Biological Chemistry. 281 (22): 15394-404. doi: ... is a transcriptional corepressor for nuclear receptors such as glucocorticoid receptors and a coactivator for estrogen ... colocalization in estrogen receptor-alpha- but not in gonadotropin-releasing hormone-positive neurons". Endocrinology. 146 (12 ... a novel human coregulator of estrogen receptor alpha". The Journal of Biological Chemistry. 276 (41): 38272-9. doi:10.1074/jbc. ...
"Regulation of thyroid hormone activation via the liver X-receptor/retinoid X-receptor pathway". The Journal of Endocrinology. ... Liver X receptor alpha (LXR-alpha) is a nuclear receptor protein that in humans is encoded by the NR1H3 gene (nuclear receptor ... peroxisome proliferator-activated receptor alpha and liver-X-receptor alpha". Molecular and Cellular Endocrinology. 146 (1-2): ... "The atypical interaction of peroxisome proliferator-activated receptor alpha with liver X receptor alpha antagonizes the ...
Retinoid signaling is transduced by 2 families of nuclear receptors, retinoic acid receptor (RAR) and retinoid X receptor (RXR ... Retinoic acid receptor alpha (RAR-α), also known as NR1B1 (nuclear receptor subfamily 1, group B, member 1) is a nuclear ... RARA codes for the nuclear hormone receptor retinoic acid receptor, alpha subtype, a transcription factor. There are another ... Kliewer SA, Umesono K, Mangelsdorf DJ, Evans RM (January 1992). "Retinoid X receptor interacts with nuclear receptors in ...
1999). "Ligand-independent coregulator recruitment by the triply activatable OR1/retinoid X receptor-alpha nuclear receptor ... peroxisome proliferator-activated receptor alpha and liver-X-receptor alpha". Mol. Cell. Endocrinol. 146 (1-2): 69-76. doi: ... Chen Y, Kerimo A, Khan S, Wei LN (2003). "Real-time analysis of molecular interaction of retinoid receptors and receptor- ... 1998). "Regulation of peroxisome proliferator-activated receptor alpha-induced transactivation by the nuclear orphan receptor ...
Nuclear receptor co-repressor 2, Promyelocytic leukemia protein, Retinoid X receptor alpha, and Von Hippel-Lindau tumor ... It is also capable of heterodimerising with COUP-TF (an orphan nuclear receptor) and retinoid X receptor (RXR) in mediating ... The other two members are Nuclear receptor 4A2 (NR4A2) and Nuclear receptor 4A3 (NR4A3). Nuclear receptor 4A1 has a high degree ... Sohn YC, Kwak E, Na Y, Lee JW, Lee SK (November 2001). "Silencing mediator of retinoid and thyroid hormone receptors and ...