The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma ... The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9 ... "Entrez Gene: IL9R interleukin 9 receptor". Sliva, D; Gu M; Zhu Y X; Chen J; Tsai S; Du X; Yang Y C (February 2000). "14-3-3zeta ... Interleukin 9 receptor (IL9R) also known as CD129 (Cluster of Differentiation 129) is a type I cytokine receptor. IL9R also ...
... interleukin-7 receptor-α (CD127) and common-γ chain receptor (CD132). The common-γ chain receptors is shared with various ... "Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor". Science. 262 (5141): 1877-80. ... Interleukin-7 receptor is expressed on various cell types, including naive and memory T cells and many others. Interleukin-7 ... The interleukin-7 receptor is a protein found on the surface of cells. It is made up of two different smaller protein chains - ...
Interleukins and Their Receptors. Cancer Treatment and Research. Vol. 80. Springer, Boston, MA. pp. 287-303. doi:10.1007/978-1- ... Interleukin 33 (IL-33) induces IL-9 expression and secretion in T cells, which was confirmed by the results obtained in mice by ... Interleukin 9, also known as IL-9, is a pleiotropic cytokine (cell signalling molecule) belonging to the group of interleukins ... Interleukin-9 has also shown to inhibit melanoma growth in mice. Additionally, it gives rise to the multiplication of ...
Interleukin-3 receptor Interleukin-9 receptor Mangs, Helena; Morris BJ (2007). "The Human Pseudoautosomal Region (PAR): Origin ... 16 (3): 233-9. doi:10.1016/j.gde.2006.04.004. PMID 16650979. Benito-Sanz S, Thomas NS, Huber C, et al. (October 2005). "A novel ... 9 (3): 395-401. doi:10.1093/hmg/9.3.395. PMID 10655549. Weng S, Stoner SA, Zhang DE (2016). "Sex chromosome loss and the ... 16 (3): 233-9. doi:10.1016/j.gde.2006.04.004. PMID 16650979. Helena Mangs A, Morris BJ (April 2007). "The Human Pseudoautosomal ...
"Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor ... Sliva D, Zhu YX, Tsai S, Kamine J, Yang YC (Sep 1999). "Tip60 interacts with human interleukin-9 receptor alpha-chain". ... Lee HJ, Chun M, Kandror KV (May 2001). "Tip60 and HDAC7 interact with the endothelin receptor a and may be involved in ... Brady ME, Ozanne DM, Gaughan L, Waite I, Cook S, Neal DE, Robson CN (Jun 1999). "Tip60 is a nuclear hormone receptor ...
... made up of the IL-22 receptor and IL-20 receptor beta subunit. Both types of receptor bind the cytokines IL-20, IL-24. Type 1 ... Interleukin 20 receptors (IL20R) belong to the IL-10 family. IL20R are involved in both pro-inflammatory and anti-inflammatory ... Receptors,+Interleukin-20 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Protein pages needing a ... January 2001). "Interleukin 20: discovery, receptor identification, and role in epidermal function". Cell. 104 (1): 9-19. doi: ...
Gately MK, Renzetti LM, Magram J, Stern AS, Adorini L, Gubler U, Presky DH (1998). "The interleukin-12/interleukin-12-receptor ... Interleukin receptors on astrocytes in the hippocampus are also known to be involved in the development of spatial memories in ... Brat DJ, Bellail AC, Van Meir EG (2005). "The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis ... The receptors can both bind all three forms of IL-1 (IL-1 alpha, IL-1 beta and IL-1 receptor antagonist). The crystal ...
The interleukin-13 receptor is a type I cytokine receptor, binding Interleukin-13. It consists of two subunits, encoded by ... "Structure of and signal transduction through interleukin-4 and interleukin-13 receptors (review)". International Journal of ... Lin C, Liu H, Zhang H, He H, Li H, Shen Z, Qin J, Qin X, Xu J, Sun Y (August 2016). "Interleukin-13 receptor α2 is associated ... Receptors,+Interleukin-13 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Articles with short ...
As a signaling molecule, interleukin 11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; ... Sims NA, Jenkins BJ, Nakamura A, Quinn JM, Li R, Gillespie MT, Ernst M, Robb L, Martin TJ (July 2005). "Interleukin-11 receptor ... Barton VA, Hall MA, Hudson KR, Heath JK (November 2000). "Interleukin-11 signals through the formation of a hexameric receptor ... Yang YC, Yin T (December 1992). "Interleukin-11 and its receptor". BioFactors. 4 (1): 15-21. PMID 1292471. Bhatia M, Davenport ...
Endometrial IL-18 receptor mRNA and the ratio of IL-18 binding protein to interleukin 18 are significantly increased in ... Jia H, Liu J, Han B (2018). "Reviews of Interleukin-37: Functions, Receptors, and Roles in Diseases". BioMed Research ... which signals through the toll/interleukin-1 receptor (TIR) domain. This signaling domain recruits MyD88 adaptor protein that ... Interleukin-18 (IL-18), also known as interferon-gamma inducing factor is a protein which in humans is encoded by the IL18 gene ...
IL-10 has been shown to interact with Interleukin 10 receptor, alpha subunit. The receptor complex for IL-10 also requires the ... Moore KW, de Waal Malefyt R, Coffman RL, O'Garra A (2001). "Interleukin-10 and the interleukin-10 receptor". Annual Review of ... Moore KW, de Waal Malefyt R, Coffman RL, O'Garra A (2001-01-01). "Interleukin-10 and the interleukin-10 receptor". Annual ... IL-10 signals through a receptor complex consisting of two IL-10 receptor-1 and two IL-10 receptor-2 proteins. Consequently, ...
The functional receptor for IL-23 (the IL-23 receptor) consists of a heterodimer between IL-12Rβ1 and IL-23R. IL-23 was first ... April 2020). "Prognostic value of serum soluble interleukin-23 receptor and related T-helper 17 cell cytokines in non-small ... June 2002). "A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, ... The IL-23 heterodimer binds the receptor complex: the p19 subunit binds IL-23R while the p40 subunit binds IL-12RB1. Receptor ...
... is a subunit of the interleukin-20 receptor, the interleukin-26 receptor, and the interleukin-24 receptor. The interleukin 20 ... "The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor ... 2003). "Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions ... IL20RA, along with the IL-20 receptor, beta subunit, form the heterodimeric interleukin-20 receptor, which binds the cytokines ...
... (IL20R2 or IL20RB) is a subunit of the interleukin-20 receptor and interleukin-22 ... December 2002). "Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand ... IL20RB also associates with IL-22 receptor, to form the heterodimeric type II interleukin-20 receptor, which also binds IL-20 ... IL20RB, along with the IL-20 receptor, alpha subunit, form the heterodimeric type I interleukin-20 receptor, which binds the ...
... (IL-17R) is a cytokine receptor which belongs to new subfamily of receptors binding proinflammatory ... "Interleukin-17C promotes Th17 cell responses and autoimmune disease via interleukin-17 receptor E". Immunity. 35 (4): 611-21. ... July 2006). "Cutting edge: interleukin 17 signals through a heteromeric receptor complex". Journal of Immunology. 177 (1): 36-9 ... November 1997). "Molecular characterization of the human interleukin (IL)-17 receptor". Cytokine. 9 (11): 794-800. doi:10.1006/ ...
Interleukin 6 receptor (IL6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. Interleukin 6 ... The interleukin-6 receptor can serve as an alpha-receptor for CTNF". J. Biol. Chem. 278 (11): 9528-35. doi:10.1074/jbc. ... The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer ... Interleukin-6 receptor has been shown to interact with Interleukin 6 and ciliary neurotrophic factor. Cluster of ...
... is a type II cytokine receptor. It binds to Interleukin-22. It is a heterodimer of α1 and IL-10Rβ2 ... Receptors,+Interleukin-22 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Protein pages needing ... Xie MH, Aggarwal S, Ho WH, Foster J, Zhang Z, Stinson J, Wood WI, Goddard AD, Gurney AL (2000). "Interleukin (IL)-22, a novel ... a picture, Genes on human chromosome 1, Genes on human chromosome 6, Type II cytokine receptors, All stub articles, Membrane ...
... is a type I cytokine receptor, binding interleukin-15. It consists of an interleukin 15 receptor, alpha ... Receptors,+Interleukin-15 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (CS1 maint: date and ... "Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes". J. ... PDB: 2B5I​Wang X, Rickert M, Garcia KC (November 2005). "Structure of the quaternary complex of interleukin-2 with its alpha, ...
The interleukin-23 receptor is a type I cytokine receptor. It is encoded in human by the IL23R gene. In complex with the ... IL23R interleukin 23 receptor". Parham C, Chirica M, Timans J, Vaisberg E, Travis M, Cheung J, et al. (June 2002). "A receptor ... Overview of all the structural information available in the PDB for UniProt: Q5VWK5 (Interleukin-23 receptor) at the PDBe-KB. ( ... interleukin-12 receptor β1 subunit (IL-12Rβ1), it is activated by the cytokine interleukin 23 (IL-23). The IL23R mRNA is 2.8 ...
... has been shown to interact with SHC1. The N-terminal (extracellular) portion of interleukin-4 receptor ... The interleukin 4 receptor is a type I cytokine receptor. It is a heterodimer, that is, composed of two subunits. IL4R is the ... forming the type II IL4 receptor). This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane ... They are required for binding of interleukin-4 to the receptor alpha chain, which is a crucial event for the generation of a ...
... a receptor subunit also shared by the receptors for interleukin 2 (IL2), interleukin 7 (IL7) and interleukin 15 (IL15). This ... Interleukin 21 receptor is a type I cytokine receptor. IL21R is its human gene. The protein encoded by this gene is a cytokine ... 2005). "Interleukin-21 receptor gene induction in human T cells is mediated by T-cell receptor-induced Sp1 activity". Mol. Cell ... 2004). "Expression of interleukin-21 receptor, but not interleukin-21, in synovial fibroblasts and synovial macrophages of ...
... which is called type I IL-1 receptor (IL-1RI). There is a third ligand of this receptor - the Interleukin 1 receptor antagonist ... "Interleukins and interleukin receptors - HUGO Gene Nomenclature Committee". www.genenames.org. Archived from the original on 15 ... April 2002). "Interleukin-1F7B (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but ... The amount of IL-18 receptor mRNA in the endometrium as well as the ratio of the amount of binding protein to interleukin is ...
Mechanistically, it was observed that 14-3-3ζ downregulates IL-1β and upregulates the IL-1 receptor antagonist, which results ... October 2020). "14-3-3ζ-TRAF5 axis governs interleukin-17A signaling". Proceedings of the National Academy of Sciences of the ... Furthermore, 14-3-3ζ may regulate glucose receptor trafficking in response to insulin levels through its interaction with IRS1 ... The physiological significance of its antigenic role remains unknown Intracellular 14-3-3ζ plays a role in interleukin-17 ...
Interleukin Interleukin 8 Interleukin 8 receptor, beta Interleukin receptor Interleukin-8 receptor GRCh38: Ensembl release 89: ... "Assignment of the genes encoding human interleukin-8 receptor types 1 and 2 and an interleukin-8 receptor pseudogene to ... Interleukin 8 receptor, alpha is a chemokine receptor. This name and the corresponding gene symbol IL8RA have been replaced by ... "Entrez Gene: IL8RA interleukin 8 receptor, alpha". Bergin DA, Reeves EP, Meleady P, Henry M, McElvaney OJ, Carroll TP, Condron ...
IL7R-α is a type I cytokine receptor and is a subunit of the functional Interleukin-7 receptor and Thymic Stromal Lymphopoietin ... "Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor ... "Entrez Gene: IL7R interleukin 7 receptor". Goodwin RG, Friend D, Ziegler SF, Jerzy R, Falk BA, Gimpel S, Cosman D, Dower SK, ... Interleukin-7 receptor subunit alpha (IL7R-α) also known as CD127 (Cluster of Differentiation 127) is a protein that in humans ...
Interleukin 8 receptor, alpha Interleukin 8 Interleukin Interleukin receptor Cluster of differentiation G protein-coupled ... "Assignment of the genes encoding human interleukin-8 receptor types 1 and 2 and an interleukin-8 receptor pseudogene to ... "Assignment of the genes encoding human interleukin-8 receptor types 1 and 2 and an interleukin-8 receptor pseudogene to ... Interleukin 8 receptor, beta is a chemokine receptor. IL8RB is also known as CXCR2, and CXCR2 is now the IUPHAR Committee on ...
"The interleukin-1 receptor/Toll-like receptor superfamily: signal generators for pro-inflammatory interleukins and microbial ... The term interleukin-1 includes IL-1α, IL-1β and Interleukin 1 receptor antagonist (IL-1Ra). IL-1Rs are involved in immune host ... There are four main groups of TIR domain-containing proteins in animals; Toll-like receptors, Interleukin-1 receptor (IL-1R), ... O'Neill LA (December 2008). "The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress". Immunological ...
"Notch Receptors and Smad3 Signaling Cooperate in the Induction of Interleukin-9-Producing T Cells". Immunity. 36 (4): 623-634. ... IL-2 is critical for interleukin-9 production by TH9 cells. IL-1 may induce IL-9 in some cases, and IL-33 is able to induce IL- ... NF-κB and NFAT1, are needed for a TCR-induced interleukin-9 production by TH9 cells. STAT5, downstream factor of IL-2, induce ... Additionally, they are defined by their high secretion of interleukin9. Besides IL-9, TH9 cells also produce IL-10 and IL-21. ...
"Interleukin-17 family and IL-17 receptors". Cytokine & Growth Factor Reviews. 14 (2): 155-74. doi:10.1016/S1359-6101(03)00002-9 ... Interleukin-25 (IL-25) - also known as interleukin-17E (IL-17E) - is a protein that in humans is encoded by the IL25 gene on ... April 2015). "Interleukin-17B Antagonizes Interleukin-25-Mediated Mucosal Inflammation". Immunity. 42 (4): 692-703. doi:10.1016 ... Angkasekwinai P, Park H, Wang YH, Wang YH, Chang SH, Corry DB, Liu YJ, Zhu Z, Dong C (July 2007). "Interleukin 25 promotes the ...
Tabira T, Chui DH, Fan JP, Shirabe T, Konishi Y (1998). "Interleukin-3 and interleukin-3 receptors in the brain". Ann. N. Y. ... interleukin-3 (IL-3), and interleukin-5 (IL-5) receptor complexes to chromosome 22q13.1". Human Genetics. 93 (2): 198-200. doi: ... Klein BK, Feng Y, McWherter CA, Hood WF, Paik K, McKearn JP (1997). "The receptor binding site of human interleukin-3 defined ... The signal transmission is ensured by high affinity between cell surface interleukin-3 receptor and IL-3. This high affinity ...