Influenza Research Database: The Influenza Research Database (IRD)IRD Influenza Research Database BRCSquires, R.B.Global spread of H5N1 in 2006: The global spread of (highly pathogenic) H5N1 in birds is considered a significant pandemic threat.Ferret: The ferret (Mustela putorius furo) is the domesticated form of the European polecat, a mammal belonging to the same genus as the weasel, Mustela of the family Mustelidae.Harris & Yalden 2008, pp.Thomas Abney (judge): Sir Thomas Abney (1690 or 1691 – 1750) was an English barrister and later judge. He was the younger son of Sir Edward Abney (who in turn was the elder brother of Sir Thomas Abney, Lord Mayor of London), by his second wife, Judith, daughter and co-heir of Peter Barr, of London.California encephalitis virusInfluenza A virus subtype H5N1: Influenza A virus subtype H5N1, also known as A(H5N1) or simply H5N1, is a subtype of the influenza A virus which can cause illness in humans and many other animal species. A bird-adapted strain of H5N1, called HPAI A(H5N1) for highly pathogenic avian influenza virus of type A of subtype H5N1, is the highly pathogenic causative agent of H5N1 flu, commonly known as avian influenza ("bird flu").Grotto of the RedemptionRotavirus: Rotavirus is the most common cause of severe diarrhoea among infants and young children. It is a genus of double-stranded RNA virus in the family Reoviridae.Influenza A virus subtype H1N1: Influenza A (H1N1) virus is the subtype of influenza A virus that was the most common cause of human influenza (flu) in 2009, and is associated with the 1918 outbreak known as the Spanish Flu.Global Vaccines: Global Vaccines, Inc is a mission-driven non-profit company applying state-of-the-art science and innovative business strategies to design and develop affordable vaccines for people in poor countries.Neuraminidase inhibitor: Neuraminidase inhibitors are a class of drugs which block the neuraminidase enzyme. They are commonly used as antiviral drugs because they block the function of viral neuraminidases of the influenza virus, by preventing its reproduction by budding from the host cell.Mycovirus: Mycoviruses (ancient Greek μύκης mykes: fungus and Latin virus) are viruses that infect fungi. The majority of mycoviruses have double-stranded RNA (dsRNA) genomes and isometric particles, but approximately 30% have positive sense, single-stranded RNA (+ssRNA) genomes.Hexon protein: In molecular biology, the hexon protein is a major coat protein found in Adenoviruses. Hexon coat proteins are synthesised during late infection and form homo-trimers.Belmont Park, Exeter: Belmont Park (also called Belmont Pleasure Grounds) is a public park in Exeter, England provided by Exeter City Council.Flu season: Flu season is an annually recurring time period characterized by the prevalence of outbreaks of influenza (flu). The season occurs during the cold half of the year in each hemisphere.Branching order of bacterial phyla (Gupta, 2001): There are several models of the Branching order of bacterial phyla, one of these was proposed in 2001 by Gupta based on conserved indels or protein, termed "protein signatures", an alternative approach to molecular phylogeny. Some problematic exceptions and conflicts are present to these conserved indels, however, they are in agreement with several groupings of classes and phyla.Tadorninae: The Tadorninae is the shelduck-sheldgoose subfamily of the Anatidae, the biological family that includes the ducks and most duck-like waterfowl such as the geese and swans.Virulence: Virulence is, by MeSH definition, the degree of pathogenicity within a group or species of parasites as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenicity of an organism - its ability to cause disease - is determined by its virulence factors.British Poultry Standard: [Poultry Standard.png|thumb|right|The front cover of the 6th Edition of the British Poultry Standards.Generalized vaccinia: Generalized vaccinia is a cutaneous condition that occurs 6-9 days after vaccination, characterized by a generalized eruption of skin lesions, and caused by the vaccinia virus.Recombination (cosmology): In cosmology, recombination refers to the epoch at which charged electrons and protons first became bound to form electrically neutral hydrogen atoms.Note that the term recombination is a misnomer, considering that it represents the first time that electrically neutral hydrogen formed.Bird trapping: Bird trapping techniques to capture wild birds include a wide range of techniques that have their origins in the hunting of birds for food. While hunting for food does not require birds to be caught alive, some trapping techniques capture birds without harming them and are of use in ornithology research.PSI-6130Coles PhillipsHHV capsid portal protein: HHV Capsid Portal Protein, or HSV-1 UL-6 protein, is the protein which forms a cylindrical portal in the capsid of Herpes simplex virus (HSV-1). The protein is commonly referred to as the HSV-1 UL-6 protein because it is the transcription product of Herpes gene UL-6.Josiah WarrenDNA sequencer: A DNA sequencer is a scientific instrument used to automate the DNA sequencing process. Given a sample of DNA, a DNA sequencer is used to determine the order of the four bases: G (guanine), C (cytosine), A (adenine) and T (thymine).Wound tumor virus: Wound tumor virus is an invertebrate and plant virus found in the United States of America belonging to the genus Phytoreovirus and the family Reoviridae. The virus is a Type III virus under the Baltimore classification system; that is it has a double-stranded RNA genome.Nudivirus: A nudivirus (family Nudiviridae) is a large, rod-shaped virus with a circular, double stranded DNA genome of 96–231 kb. The genome encodes 98 to 154 open reading frames.Subtherapeutic antibiotic use in swine: Antibiotics are commonly used in commercial swine production in the United States and around the world. They are used for disease treatment, disease prevention and control, and growth promotion.Defective interfering particle: In virology, defective interfering particles (DIPs), also known as defective interfering viruses, are spontaneously generated virus mutants in which a critical portion of the particle's genome has been lost due to defective replication. DIPs are derived from and associated with their parent virus, and particles are classed as DIPs if they are rendered non-infectious due to at least one essential gene of the virus being lost or severely damaged as a result of the defection.Kennel clubReverse genetics: thumbnail|300px|[[Avian Flu vaccine development by Reverse Genetics techniques. Courtesy: National Institute of Allergy and Infectious Diseases]]Chicken as biological research model: Chickens (Gallus gallus domesticus) and their eggs have been used extensively as research models throughout the history of biology. Today they continue to serve as an important model for normal human biology as well as pathological disease processes.Sindbis virusInfluenza virus nucleoprotein: Influenza virus nucleoprotein (NP) is a structural protein which encapsidates the negative strand viral RNA. NP is one of the main determinants of species specificity.CD46: CD46 complement regulatory protein also known as CD46 (cluster of differentiation 46) and Membrane Cofactor Protein is a protein which in humans is encoded by the CD46 gene. CD46 is an inhibitory complement receptor.Rabies virus: The rabies virus is a neurotropic virus that causes rabies in humans and animals. Rabies transmission can occur through the saliva of animals and less commonly through contact with human saliva.Permissive temperature: The permissive temperature is the temperature at which a temperature sensitive mutant gene product takes on a normal, functional phenotype.http://www.Simon Carpenter: Dr. Simon Carpenter, Head of the Entomology and Modelling Group in the Vector-borne Diseases Programme at the UK Biotechnology and Biological Sciences Research Council Institute for Animal Health’s Pirbright Laboratory in Woking, Surrey, is an entomologist who was awarded the first Rooker Prize in 2009 in recognition of his research on biting midges that transmit bluetongue virus (BTV), the causative agent of bluetongue disease, an important orbivirus disease of ruminants.Schmallenberg virus: Schmallenberg virus is the informal name given to a recently isolated orthobunyavirus, which has not been given a formal name , initially reported in November 2011 to cause congenital malformations and stillbirths in cattle, sheep, goats, and possibly alpaca. It appears to be transmitted by midges (Culicoides spp.Baby hamster kidney cell: Baby Hamster Kidney fibroblasts (aka BHK cells) are an adherent cell line used in molecular biology.Plaque reduction neutralization test: The Plaque reduction neutralization test is used to quantify the titre of neutralising antibody for a virus.Hepatitis B virus precore mutant: A precore mutant is a variety of hepatitis B virus that does not produce hepatitis B virus e antigen (HBeAg). These mutants are important because infections caused by these viruses are difficult to treat, and can cause infections of prolonged duration and with a higher risk of liver cirrhosis.Distributed cache: In computing, a distributed cache is an extension of the traditional concept of cache used in a single locale. A distributed cache may span multiple servers so that it can grow in size and in transactional capacity.West Nile virus in the United States: The West Nile virus quickly spread across the United States after the first reported cases in Queens, New York in 1999. The virus is believed to have entered in an infected bird or mosquito, although there is no clear evidence.Bunyamwera virus: The Bunyamwera virus is a negative-sense single stranded enveloped RNA virus. It is the type species of the Orthobunyavirus genus, in the Bunyaviridae family.Pandemic: A pandemic (from Greek πᾶν pan "all" and δῆμος demos "people") is an epidemic of infectious disease that has spread through human populations across a large region; for instance multiple continents, or even worldwide. A widespread endemic disease that is stable in terms of how many people are getting sick from it is not a pandemic.Vesicular stomatitis virus: Vesicular stomatitis Indiana virus (VSIV) (often still referred to as VSV) is a virus in the family Rhabdoviridae; the well-known rabies virus belongs to the same family. VSIV can infect insects, cattle, horses and pigs.Phenotype microarray: The phenotype microarray approach is a technology for high-throughput phenotyping of cells.Intussusception (medical disorder)RNA-binding protein database: The RNA-binding Proteins Database (RBPDB) is a biological database of RNA-binding protein specificities that includes experimental observations of RNA-binding sites. The experimental results included are both in vitro and in vivo from primary literature.Natural transfer: The natural transfer (hypothesis or theory), in reference to the HIV/AIDS pandemic, states that humans first received HIV by contact with primates, presumably from a fight with a Chimpanzee during hunting or consumption of primate meat, and became contaminated with simian immunodeficiency virus (SIV). According to the 'Hunter Theory', the virus was transmitted from a chimpanzee to a human when a bushmeat hunter was bitten or cut while hunting or butchering an animal.