RNA-Seq). Recently some progress has been made to characterize known isoforms of regeneration associated genes (RAGs) using RNA ... So it's hypothesized that Pten J2 works as regulatory RNA to inhibit the activity of Pten. Protein isoform Mitchell PJ, Tjian R ... Four Atf3 isoforms were identified in dorsal root ganglia (DRG) so far. These four isoforms differ in TSS, and one differs in ... "Isoform diversity and regulation in peripheral and central neurons revealed through RNA-Seq". PLOS ONE. 7 (1): e30417. Bibcode: ...

Isoforms at the RNA level are readily characterized by cDNA transcript studies. Many human genes possess confirmed alternative ... G6PDA: normal ratio of active isoforms in cells of any tissue is 1:1 shared with G6PDG. This is precisely the normal isoform ... While many perform the same or similar biological roles, some isoforms have unique functions. A set of protein isoforms may be ... MeSH entry protein isoforms Definitions Isoform (CS1 errors: missing periodical, Articles with short description, Short ...

IsoDOT - Differential RNA-isoform Expression. Limma Limma powers differential expression analyses for RNA-sequencing and ... RNA-Skim RNA-Skim: a rapid method for RNA-Seq quantification at transcript-level. rSeq rSeq is a set of tools for RNA-Seq data ... The traditional RNA-Seq methodology is commonly known as "bulk RNA-Seq", in this case RNA is extracted from a group of cells or ... Rail-RNA Scalable analysis of RNA-seq splicing and coverage. RAP RNA-Seq Analysis Pipeline, a new cloud-based NGS web ...

PELP1 binds RNA, and participates in RNA splicing. The PELP1-regulated genome includes several uniquely spliced isoforms. ... Currently, there are two known isoforms (long 3.8 Kb and short 3.4 Kb) and short isoform is widely expressed in cancer cells. ... Mechanistic studies showed that PELP1 interaction with the arginine methyltransferase PRMT6 plays a role in RNA splicing. PELP1 ... plays critical roles in 60S ribosomal subunit synthesis and ribosomal RNA transcription. The SENP3-associated complex ...

RNA-seq data shows increased CXorf38 expression in a variety of cancers with the greatest expression in endometrial cancer, ... Isoform 1, the canonical sequence, has 7 exons. The remaining isoforms are missing various exons and/or have varying 5'UTR or ... CXorf38 isoform 1 is predicted to have various post-translational modifications such as N-terminal methionine cleavage, ... Yang F, Babak T, Shendure J, Disteche CM (May 2010). "Global survey of escape from X inactivation by RNA-sequencing in mouse". ...

These unique combinations of exons are termed RNA transcript isoforms. The transcriptome is a set of all RNA, including rRNA, ... RNA-seq uses reverse transcriptase to convert the mRNA template to cDNA. During library preparation, the cDNA is fragmented ... After sequencing RNA-seq analysis can then be performed. Noninvasive method for capturing mRNA from single cells in living, ... The current RNA capture methods involve sorting cells in suspension from acutely dissociated tissue, and thus can lose ...

Shur I, Ben-Avraham D, Benayahu D (June 2004). "Alternatively spliced isoforms of a novel stromal RNA regulating factor". Gene ... RNA. 14 (10): 2038-49. doi:10.1261/rna.1212008. PMC 2553740. PMID 18719244. Wu Z, Yates AL, Hoyne GF, Goodnow CC (July 2010). " ... "Consequences of increased CD45RA and RC isoforms for TCR signaling and peripheral T cell deficiency resulting from ...

... protein Isoform 1 is 365 amino acids long. Isoform 2 and Isoform 3 are 357 and 300 amino acids respectively. There is a ... C8orf58 chromosome 8 open reading frame 58 [Homo sapiens (human)]. [3] RNA Folding Form TargetScan Human NCBI Protein. ... C8orf58 Isoform 1 has a molecular weight of 39.7 kDa and an isoelectric point of 8.29. It is proline and arginine rich and ... Uncharacterized protein C8orf58 isoform 1 [Homo sapiens].[4] SDSC Biology Workbench Chou-Fasman Secondary Structure Prediction ...

It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y ... Alternative splicing results in multiple transcript variants encoding different isoforms. GRCh38: Ensembl release 89: ... 2000). "Identification of two novel proteins that interact with germ-cell-specific RNA-binding proteins DAZ and DAZL1". ... 1995). "Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene ...

RNA splicing is another mechanism influencing NKG2D ligand expression. For MICA, ULBP4 and ULBP5, alternative splicing isoforms ... In mice, alternative splicing generates two distinct NKG2D isoforms: the long one (NKG2D-L) and the short one (NKG2D-S). NKG2D- ... In mice, both NKG2D isoforms were detected. During resting state, predominance of long forms of NKG2D is typical, while in ... 2009-02-18). "Cellular expression, trafficking, and function of two isoforms of human ULBP5/RAET1G". PLOS ONE. 4 (2): e4503. ...

1992). "Multiple Rh messenger RNA isoforms are produced by alternative splicing". Blood. 80 (4): 1074-8. doi:10.1182/blood. ... Alternative splicing of this gene results in four transcript variants encoding four different isoforms. A recent study in the ...

"protein YIF1A isoform 2 [Homo sapiens] - Protein - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2020-07-28. "protein YIF1A isoform 1 ... "RBPDB: The database of RNA-binding specificities". rbpdb.ccbr.utoronto.ca. Retrieved 2020-08-01. "SAPS < Sequence Statistics < ... The longest protein isoform of YIF1A is 293 amino acids in length. It has an observed molecular weight of approximately 32.0 ... YIF1A has isoforms 1 and 2, with exons 8 and 7 respectively. The two transcripts undergo alternate splicing and are translated ...

"Transmembrane protein 171 isoform X1". NCBI Protein. "RBPDB: The database of RNA-binding protein specificities". "Anti-TMEM171 ... TMEM171 has isoforms 1, 2, and X1, with 4 exons each. The 3 transcripts undergo alternate in-frame splicing and are translated ... The longest protein isoform of TMEM171 is 324 amino acids in length and has an observed molecular weight of approximately 44 ... Hao S, Lv J, Yang Q, Wang A, Li Z, Guo Y, Zhang G (April 2019). "Identification of Key Genes and Circular RNAs in Human Gastric ...

It is alternatively spliced into multiple isoforms. Long noncoding RNA GRCh38: Ensembl release 89: ENSG00000240288 - Ensembl, ... In molecular biology, ghrelin opposite strand (non-protein coding), also known as GHRLOS, is a long non-coding RNA. It is ... a candidate non-coding RNA gene". BMC Mol Biol. 9: 95. doi:10.1186/1471-2199-9-95. PMC 2621237. PMID 18954468. (Genes on human ...

Micro RNA (miR-483) over expression has been shown to knock down C16orf82 expression. The C16orf82 protein is 154 amino acids ... There are no known variants or isoforms of C16orf82. C16orf82 contains one domain, DUF4694, which currently has a function that ... both by microarray experiments as well as RNA-seq. C16orf82 expression is also highly variable between individuals, with some ...

With the accumulation of RNA-seq data that are capable of estimating expression profiles for alternatively spliced isoforms, ... "Systematically differentiating functions for alternatively spliced isoforms through integrating RNA-seq data". PLOS ... Li HD, Menon R, Omenn GS, Guan Y (August 2014). "The emerging era of genomic data integration for analyzing splice isoform ... While techniques such as microarray analysis, RNA interference, and the yeast two-hybrid system can be used to experimentally ...

... (maternally expressed 3) is a maternally expressed, imprinted long non-coding RNA gene. At least 12 different isoforms of ... Zhang X, Zhou Y, Mehta KR, Danila DC, Scolavino S, Johnson SR, Klibanski A (November 2003). "A pituitary-derived MEG3 isoform ... Long noncoding RNA GRCh38: Ensembl release 89: ENSG00000214548 - Ensembl, May 2017 "Human PubMed Reference:". National Center ... August 2007). "Activation of p53 by MEG3 non-coding RNA". The Journal of Biological Chemistry. 282 (34): 24731-42. doi:10.1074/ ...

Alternatively spliced transcript variants encoding different isoforms have been identified[citation needed]. Somatic mutations ... This gene encodes a small (~35 kDa) subunit which plays a critical role in RNA splicing by recognizing and binding to AG ... "Entrez Gene: U2AF1 U2 small nuclear RNA auxiliary factor 1". Zamore PD, Green MR (1989). "Identification, purification, and ... U2 small nuclear RNA auxiliary factor 1 has been shown to interact with: ASF/SF2, NXF1, RP9, SMNDC1, U2AF2, and ZRANB2. GRCh38 ...

No evidence for micro RNA or pseudogenes has been found. The gene does not have various isoforms, only transcript variant 1X ...

Arzalluz-Luque Á, Conesa A (August 2018). "Single-cell RNAseq for the study of isoforms-how is that possible?". Genome Biology ... An RNA timestamp is a technology that enables the age of any given RNA transcript to be inferred by exploiting RNA editing. In ... An RNA timestamp can be tagged to a RNA of interest, thus new RNA timestamps will be generated with transcriptional pulses of ... A RNA timestamp is a repetitive reporter RNA motif that gradually undergoes adenosine to inosine (A-to-I) edits. RNA timestamps ...

Each of these proteins have different isoforms due to differential RNA splicing. The isoforms of GRIP-1 are named GRIP-1a and ... it now appears that the GRIP-1 isoforms are involved differentially with the stabilization of AMPA receptors after being ... GRIP-1b while those of ABP-L are distinguished as ABP-L and pABP-L. The apparent difference in both cases is that one isoform ( ...

... messenger RNA is alternatively spliced to produce three predicted protein isoforms. Starting from the N-terminus, the ... Isoforms two and three have missing or incomplete C-terminal SET domains respectively. G9A-like protein (GLP) shares an ... canonical isoform one has eight ankyrin repeats, a pre-SET, and a SET domains. ...

Circular RNAs are the predominant transcript isoform from hundreds of human genes in diverse cell types. PLoS One 2012;7(2): ... Circular RNAs are abundant, conserved, and associated with ALU repeats. RNA 2013;19(2):141-57. Zhang Y, Zhang XO, Chen T, et al ... RNA splicing is a process in molecular biology where a newly-made precursor messenger RNA (pre-mRNA) transcript is transformed ... RNA 2014;20(9):1476-87. Virtual Cell Animation Collection: mRNA Splicing RNA+Splicing at the U.S. National Library of Medicine ...

"Systematically Differentiating Functions for Alternatively Spliced Isoforms through Integrating RNA-seq Data". PLOS ... "The emerging era of genomic data integration for analyzing splice isoform function". Trends in Genetics. 30 (8): 340-7. doi: ... activity Predicting binding sites of Calmodulin binding proteins Predicting function for alternatively spliced isoforms Li, ...

Combined RNA-Seq and proteomics analyses have revealed striking differential expression of splice isoforms of key proteins in ... For instance, isoform.io, a platform guided by protein structure predictions, has evaluated hundreds of thousands of isoforms ... There are two major types of cis-acting RNA sequence elements present in pre-mRNAs and they have corresponding trans-acting RNA ... RNA. 14 (5): 802-13. doi:10.1261/rna.876308. PMC 2327353. PMID 18369186. Barash Y, Calarco JA, Gao W, Pan Q, Wang X, Shai O, et ...

Probable RNA-binding protein 23 is a protein that in humans is encoded by the RBM23 gene. This gene encodes a member of the ... Multiple transcript variants encoding different isoforms have been found for this gene. GRCh38: Ensembl release 89: ... "Entrez Gene: RBM23 RNA binding motif protein 23". Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to ... Overview of all the structural information available in the PDB for UniProt: Q86U06 (Probable RNA-binding protein 23) at the ...

"U1 snRNP determines mRNA length and regulates isoform expression". Cell. 150 (1): 53-64. doi:10.1016/j.cell.2012.05.029. PMC ... U1 spliceosomal RNA is the small nuclear RNA (snRNA) component of U1 snRNP (small nuclear ribonucleoprotein), an RNA-protein ... Page for U1 spliceosomal RNA at Rfam (GO template errors, Small nuclear RNA, Spliceosome, RNA splicing). ... MicroRNA Small nuclear RNA U2 spliceosomal RNA Nagai K, Muto Y, Pomeranz Krummel DA, Kambach C, Ignjatovic T, Walke S, ...

Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ... 40S ribosomal protein S4, Y isoform 1 is a protein that in humans is encoded by the RPS4Y1 gene. Cytoplasmic ribosomes, ... Watanabe M, Zinn AR, Page DC, Nishimoto T (1993). "Functional equivalence of human X- and Y-encoded isoforms of ribosomal ... The 3 isoforms encoded by these genes are not identical, but appear to be functionally equivalent. Ribosomal protein S4 belongs ...

Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ... 40S ribosomal protein S4, X isoform is a protein that in humans is encoded by the RPS4X gene. Ribosomes, organelles that ... Watanabe M, Zinn AR, Page DC, Nishimoto T (1993). "Functional equivalence of human X- and Y-encoded isoforms of ribosomal ... The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the ...

... is a micropeptide encoded in the mitochondrial genome by the 16S ribosomal RNA gene, MT-RNR2. Its structure contains a ... It is not entirely sure whether these paralogous isoforms are completely unexpressed. The expressed peptide contains a three- ... Humanin is encoded in the mitochondrial genome by the 16S ribosomal RNA gene, MT-RNR2. Multiple paralogs are found in the ... "Evidence for potential functionality of nuclearly-encoded humanin isoforms". Genomics. 94 (4): 247-56. doi:10.1016/j.ygeno. ...

RNA splicing studies are focused on understanding the regulation of different transcript isoforms. Single cell transcriptomics ... Chen KH, Boettiger AN, Moffitt JR, Wang S, Zhuang X (April 2015). "RNA imaging. Spatially resolved, highly multiplexed RNA ... RNA expression can serve as a proxy for protein abundance. However, protein abundance is governed by the complex interplay ... The first step in quantifying the transcriptome is to convert RNA to cDNA using reverse transcriptase so that the contents of ...

Two transcript variants encoding two different isoforms have been found for this gene. Also, at least two other transcript ... the protein is also encoded by some RNA viruses of the Potyviridae family. ...

The co-assembly of these two isoforms generate receptors with reduced calcium permeability. RNA editing of the Q/R site can ... The type of RNA editing that occurs in the pre-mRNA of GluR6 is Adenosine to Inosine (A to I) editing. A to I RNA editing is ... as well as RNA splicing, is determined by RNA editing events of the individual subunits, explaining their extremely high ... This can lead to translation of a protein isoform due to a change in its primary protein structure. Therefore, editing can also ...