... is also used to treat short QT syndrome. Eli Lilly has discontinued manufacture of parenteral quinidine gluconate in ... Quinidine-based ligands are used in AD-mix-β for Sharpless asymmetric dihydroxylation. Quinidine sulfate is used in the ... The dose of quinidine (10mg two times daily) is about 1/40th of a relatively low antiarrhythmic dose (400mg, twice or 3 times ... Quinidine is also an inhibitor of the cytochrome P450 enzyme 2D6, and can lead to increased blood levels of lidocaine, beta ...
... dextromethorphan hydrobromide 30 mg/quinidine sulfate 10 mg (N=110) Nuedexta - dextromethorphan hydrobromide 20 mg/quinidine ... Quinidine sulfate affects the way the heart beats, and is generally used in people with certain heart rhythm disorders. It is ... Dextromethorphan/quinidine is a combination of these two generic drugs, and is the first FDA-approved drug for the treatment of ... "Quinidine sulfate". PDRhealth™. 2016. Archived from the original on 2015-09-05. Retrieved 2016-02-18. "Label: NUEDEXTA- ...
Quinidine is an antiarrhythmic drug that may reduce the chance of serious abnormal heart rhythms occurring in some people with ... Yang F, Hanon S, Lam P, Schweitzer P (April 2009). "Quinidine revisited". The American Journal of Medicine. 122 (4): 317-21. ... Belhassen B, Glick A, Viskin S (September 2004). "Efficacy of quinidine in high-risk patients with Brugada syndrome". ... while quinidine may be used longer term. Testing people's family members may be recommended. The condition affects between 1 ...
... (and quinidine) are used as the chiral moiety for the ligands used in Sharpless asymmetric dihydroxylation as well as ... No injectable preparation of quinine is licensed in the US; quinidine is used instead. Quinine is a flavor component of tonic ... Centers for Disease Control and Prevention (April 1991). "Treatment with quinidine gluconate of persons with severe Plasmodium ... September 2005). "Effects of quinine, quinidine, and chloroquine on alpha9alpha10 nicotinic cholinergic receptors". Molecular ...
... 's Class 1a activity is similar to that of quinidine in that it targets sodium channels to inhibit conduction. ... Quinidine, procainamide and disopyramide". Drug Safety. 5 (6): 393-420. doi:10.2165/00002018-199005060-00002. PMID 2285495. ... in higher doses compared to quinidine. Levites proposed a possible secondary mode of action for disopyramide, against reentrant ... "Effects of intravenous disopyramide and quinidine on normal myocardium and on the characteristics of arrhythmias: ...
Dykstra SJ, Minielli JL, Lawson JE, Ferguson HC, Dungan KW (September 1973). "Lysergic acid and quinidine analogs. 2-(o- ...
Quinimax and quinidine are the two most commonly used alkaloids related to quinine in the treatment or prevention of malaria. ... Quinidine is a direct derivative of quinine. It is a distereoisomer, thus having similar anti-malarial properties to the parent ... Quinidine is recommended only for the treatment of severe cases of malaria. Warburg's tincture was a febrifuge developed by ... Quinimax is a combination of four alkaloids (quinine, quinidine, cinchonine and cinchonidine). This combination has been shown ...
Quinidine : Increased anticholinergic action (particular on AV conduction). Antipsychotics : Long term use of trihexyphenidyl ...
Quinidine : Increased anticholinergic action (particular on AV conduction). Antipsychotics : Long-term use of biperiden may ...
While procainamide and quinidine may be used in the conversion of atrial fibrillation to normal sinus rhythm, they should only ... Class Ia agents include quinidine, procainamide and disopyramide. Class Ib antiarrhythmic agents are sodium channel blockers. ... because procainamide and quinidine can increase the conduction through the AV node and may cause 1:1 conduction of atrial ...
It has a quinidine-like anti-arrhythmic effect. It has vasodilatory properties and can therefore reduce blood pressure. ...
Procainamide, quinidine and disopyramide are Class Ia agents. Class 1b drugs lengthen phase 3 repolarization. They include ...
Two more key alkaloids, quinidine and cinchonidine, were later identified and it became a routine in quinology to examine the ... The bark contains alkaloids, including quinine and quinidine. Cinchona is the only economically practical source of quinine, a ... Cinchona alkaloids include: cinchonine and cinchonidine (stereoisomers with R1 = vinyl, R2 = hydrogen) quinine and quinidine ( ...
Medications indicated for: Irregular heartbeat, e.g. disopyramide, quinidine. Drug-induced arrhythmia worsened by ...
... taken with quinidine was found to produce respiratory depression, indicative of central opioid action. High doses of ... Concurrent administration of P-glycoprotein inhibitors such as quinidine potentially allows loperamide to cross the blood-brain ... Common P-glycoprotein inhibitors include quinidine, ritonavir, and ketoconazole. Loperamide is capable of decreasing the ...
Quinidine may interact with chlorpromazine to increase myocardial depression. Likewise, it may also antagonize the effects of ... Other drugs that prolong the QT interval, such as quinidine, verapamil, amiodarone, sotalol and methadone, may also interact ...
Quinidine also increases levels of amikacin in the body. The NSAID indomethacin can increase serum aminoglycoside levels in ...
Relevance to dextromethorphan/quinidine (Nuedexta®) clinical use". Pharmacol. Ther. 164: 170-82. doi:10.1016/j.pharmthera. ...
Due to the loss of Indonesia in World War II, the source for cinchona alkaloids, a precursor of quinidine, was reduced. This ... As a result, procaine was discovered, which has similar cardiac effects as quinidine. In 1936 it was found by Mautz that by ... These were the cardiac glycosides, quinidine, propranolol, lidocaine and diphenylhydantoin. In January 1996, extended release ... but it had the same toxicity profile as quinidine, and it could cause systemic lupus erythematosus-like syndrome. These ...
Woodhall B, Sealy WC, Hall KD, Floyd WL (July 1960). "Craniotomy under conditions of quinidine-protected cardioplegia and ... Woodhall B, Sealy WC, Hall KD, Floyd WL (July 1960). "Craniotomy under conditions of quinidine-protected cardioplegia and ... Woodhall B, Sealy WC, Hall KD, Floyd WL (July 1960). "Craniotomy under conditions of quinidine-protected cardioplegia and ...
Quinidine, reduces urinary excretion of quinidine, hence increasing the potential for toxicity. Salicylates, potential for ...
Quinidine toxicity can lead to cinchonism and also to quinine amaurosis.[citation needed] Those experiencing amaurosis are ...
Other alkaloids that are extracted from this tree include cinchonine, cinchonidine and quinidine. Standley, Paul C. (1936). " ...
Drugs such as quinidine may be both reverse use dependent and use dependent. Examples of calcium-activated potassium channel ... Reverse use dependent drugs that slow heart rate (such as quinidine) can be less effective at high heart rates. The ... such as quinidine) are more efficacious at preventing a tachyarrhythmia than converting someone into normal sinus rhythm.[ ... Bupivacaine Quinidine Fluoxetine Seproxetine (Norfluoxetine) 12-O-tetradecanoylphorbol-13-acetate (TPA) (phorbol 12-myristate ...
Protoporphyrin IX Complexes of the Antimalarial Cinchona Alkaloids Quinine and Quinidine". ACS Chemical Biology. 7 (4): 666-71 ...
April 2007). "Electrical storms in Brugada syndrome successfully treated with isoproterenol infusion and quinidine orally". ...
... shows membrane-stabilizing effects like quinidine, possibly accounting for its antiarrhythmic effects. It also acts as ...
... concomitant administration of fluconazole and quinidine, especially when fluconazole is administered in high dosages; take ...
... and Quinidine". Annual Review of Pharmacology and Toxicology. 16: 189-99. doi:10.1146/annurev.pa.16.040176.001201. PMID 779614 ...
Long QT syndrome Torsades de pointes Roden DM, Woosley RL, Primm RK (1986). "Incidence and clinical features of the quinidine- ... TdP is seen more frequently with therapeutic levels of quinidine. Sodium blocking activity is dominant with subtherapeutic ... blocking activity takes precedence over the sodium channel blocking activity Disopyramide Procainamide Propafenone Quinidine ...