Pyridoxal
... that are capable of producing pyridoxal. Pyridoxal is involved in what is believed to be the most ancient reaction of aerobic ... Pyridoxal is one form of vitamin B6. Some medically relevant bacteria, such as those in the genera Granulicatella and ... Pyridoxal phosphate "Protein Domain Structure Uncovers the Origin of Aerobic Metabolism and the Rise of Planetary Oxygen", ... In in vitro culture, these pyridoxal-dependent bacteria may only grow in areas surrounding colonies of bacteria from other ...
Pyridoxal phosphate
... (PLP, pyridoxal 5'-phosphate, P5P), the active form of vitamin B6, is a coenzyme in a variety of enzymatic ... Pyridoxal phosphate has numerous roles in human body. A few examples below: Metabolism and biosynthesis of serotonin. Pyridoxal ... Pyridoxal phosphate is a cofactor of ornithine carboxylase. Transamination. Pyridoxal phosphate takes part in decomposition and ... PLP is synthesized from pyridoxal by the enzyme pyridoxal kinase, requiring one ATP molecule. PLP is metabolized in the liver. ...
Pyridoxal oxidase
In enzymology, a pyridoxal oxidase (EC 1.2.3.8) is an enzyme that catalyzes the chemical reaction pyridoxal + H2O + O2 ⇌ {\ ... I. Preliminary studies of pyridoxal oxidase". Mol. Gen. Genet. 180 (2): 449-453. doi:10.1007/BF00425861. Portal: Biology v t e ... The systematic name of this enzyme class is pyridoxal:oxygen 4-oxidoreductase. This enzyme participates in vitamin B6 ... Hanly EW (1980). "Preliminary characterization and physical properties of pyridoxal oxidase activity from Drosophila ...
Pyridoxal kinase
Other names in common use include pyridoxal kinase (phosphorylating), pyridoxal 5-phosphate-kinase, pyridoxal phosphokinase, ... In enzymology, a pyridoxal kinase (EC 2.7.1.35) is an enzyme that catalyzes the chemical reaction ATP + pyridoxal ⇌ {\ ... displaystyle \rightleftharpoons } ADP + pyridoxal 5'-phosphate Thus, the two substrates of this enzyme are ATP and pyridoxal, ... "Biosynthesis of pyridoxal phosphate by liver sections of rat in vitro". Byull. Eksp. Biol. Med. 22: 40-43. Portal: Biology v t ...
Pyridoxal phosphatase
The enzyme pyridoxal phosphatase (EC 3.1.3.74) catalyzes the reaction pyridoxal 5′-phosphate + H2O ⇌ {\displaystyle \ ... Jang, Y.M.; Kim, DW; Kang, TC; Won, MH; Baek, NI; Moon, BJ; Choi, SY; Kwon, OS (2003). "Human pyridoxal phosphatase. Molecular ... The systematic name is pyridoxal-5′-phosphate phosphohydrolase. Other names in common use include vitamine B6 (pyridoxine) ... Fonda ML, Zhang YN (1995). "Kinetic mechanism and divalent metal activation of human erythrocyte pyridoxal phosphatase". Arch. ...
Pyridoxal 4-dehydrogenase
In enzymology, a pyridoxal 4-dehydrogenase (EC 1.1.1.107) is an enzyme that catalyzes the chemical reaction pyridoxal + NAD+ ... The systematic name of this enzyme class is pyridoxal:NAD+ 4-oxidoreductase. This enzyme is also called pyridoxal dehydrogenase ... Pyridoxal dehydrogenase and 4-pyridoxolactonase". J. Biol. Chem. 244 (10): 2585-9. PMID 4306030. Portal: Biology v t e (EC 1.1. ... displaystyle \rightleftharpoons } 4-pyridoxolactone + NADH + H+ Thus, the two substrates of this enzyme are pyridoxal and NAD+ ...
Magnesium pyridoxal 5-phosphate glutamate
... (trade name Sedalipid) is a hypolipidemic agent. Schuitemaker GE, van der Pol GA, ... Aretz CP, Dinant GJ (2001). "A placebo-controlled, double-blind, randomised trial of magnesium-pyridoxal-5'-phosphate-glutamate ...
Group III pyridoxal-dependent decarboxylases
Group I pyridoxal-dependent decarboxylases Group II pyridoxal-dependent decarboxylases Group IV pyridoxal-dependent ... Pyridoxal-5'-phosphate-dependent amino acid decarboxylases can be divided into four groups based on amino acid sequence. Group ... The major domain contains a conserved lysine residue, which is the site of attachment of the pyridoxal-phosphate group. ... In molecular biology, group III pyridoxal-dependent decarboxylases are a family of bacterial enzymes comprising ornithine ...
Group II pyridoxal-dependent decarboxylases
Group I pyridoxal-dependent decarboxylases Group III pyridoxal-dependent decarboxylases Group IV pyridoxal-dependent ... Pyridoxal-5'-phosphate-dependent amino acid decarboxylases can be divided into four groups based on amino acid sequence. Group ... In molecular biology, group II pyridoxal-dependent decarboxylases are family of enzymes including aromatic-L-amino-acid ... Sandmeier E, Hale TI, Christen P (May 1994). "Multiple evolutionary origin of pyridoxal-5'-phosphate-dependent amino acid ...
Group IV pyridoxal-dependent decarboxylases
Group I pyridoxal-dependent decarboxylases Group II pyridoxal-dependent decarboxylases Group III pyridoxal-dependent ... Pyridoxal-5'-phosphate-dependent amino acid decarboxylases can be divided into four groups based on amino acid sequence. Group ... The proteins contain a conserved lysine residue which is known, in mouse ODC to be the site of attachment of the pyridoxal- ... In molecular biology, group IV pyridoxal-dependent decarboxylases are a family of enzymes comprising ornithine decarboxylase EC ...
Group I pyridoxal-dependent decarboxylases
Group II pyridoxal-dependent decarboxylases Group III pyridoxal-dependent decarboxylases Group IV pyridoxal-dependent ... GDC consists of four proteins P, H, L and T. Pyridoxal-5'-phosphate-dependent amino acid decarboxylases can be divided into ... The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor, carbon dioxide is released and ... In molecular biology, the group I pyridoxal-dependent decarboxylases, also known as glycine cleavage system P-proteins, are a ...
Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing)
Pyridoxal 5′-phosphate synthase (glutamine hydrolysing) (EC 4.3.3.6, PdxST) is an enzyme with systematic name D-ribose 5- ... Pyridoxal+5'-phosphate+synthase+(glutamine+hydrolyzing) at the U.S. National Library of Medicine Medical Subject Headings (MeSH ... Hanes JW, Keresztes I, Begley TP (July 2008). "13C NMR snapshots of the complex reaction coordinate of pyridoxal phosphate ... Raschle T, Amrhein N, Fitzpatrick TB (September 2005). "On the two components of pyridoxal 5'-phosphate synthase from Bacillus ...
Diaminopimelate decarboxylase
"Pyridoxal phosphate". Pubchem. Retrieved 2018-03-09. Gillner DM, Becker DP, Holz RC (February 2013). "Lysine biosynthesis in ... It employs the cofactor pyridoxal phosphate, also known as PLP, which participates in numerous enzymatic transamination, ... Portal: Biology (EC 4.1.1, Pyridoxal phosphate enzymes, Enzymes of known structure). ...
Branched-chain amino acid aminotransferase
Pyridoxal Phosphate Enzymology. 1814 (11): 1405-6. doi:10.1016/j.bbapap.2011.08.007. PMID 21871586. Yennawar NH, Islam MM, ... Like other transaminase enzymes (as well as many enzymes of other classes), BCATs require the cofactor pyridoxal-5'-phosphate ( ... Toney MD (November 2011). "Pyridoxal phosphate enzymology". Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. ...
PDXK
Pyridoxal kinase is an enzyme that in humans is encoded by the PDXK gene. The protein encoded by this gene phosphorylates ... "Entrez Gene: PDXK pyridoxal (pyridoxine, vitamin B6) kinase". Chern CJ, Beutler E (1976). "Biochemical and electrophoretic ... 2004). "Expression of a novel pyridoxal kinase mRNA splice variant, PKH-T, in human testis". Asian J. Androl. 6 (2): 83-91. ... Hanna MC, Turner AJ, Kirkness EF (May 1997). "Human pyridoxal kinase. cDNA cloning, expression, and modulation by ligands of ...
3-Hydroxyisonicotinaldehyde
HINA has been used as an analogue of pyridoxal 5′-phosphate, the active form of the coenzyme vitamin B6. It is an especially ... Harris, C.; Johnson, R.; Metzler, D. (1976). "Band-shape analysis and resolution of electronic spectra of pyridoxal phosphate ... doi:10.1016/0304-5102(91)85059-B. Nakamoto, Kazuo; Martell, A. E. (1959). "Pyridoxine and Pyridoxal Analogs. IV. Ultraviolet ... Heinert, Dietrich; Martell, Arthur E. (1958). "Studies on pyridoxine and pyridoxal analogs-I". Tetrahedron. 3: 49-61. doi: ...
Histidine decarboxylase
"Pyridoxal phosphate-dependent decarboxylase". InterPro. Toney MD (January 2005). "Reaction specificity in pyridoxal phosphate ... HDC contains several regions that are sequentially and structurally similar to those in a number of other pyridoxal-dependent ... The enzyme employs a pyridoxal 5'-phosphate (PLP) cofactor, in similarity to many amino acid decarboxylases. Eukaryotes, as ... Histidine decarboxylase is a group II pyridoxal-dependent decarboxylase, along with aromatic-L-amino-acid decarboxylase, and ...
Cystathionine beta-lyase
The enzyme belongs to the γ-family of PLP-dependent enzymes due to its use of a pyridoxal-5'-phosphate (PLP) cofactor to cleave ... Clausen T, Huber R, Laber B, Pohlenz HD, Messerschmidt A (September 1996). "Crystal structure of the pyridoxal-5'-phosphate ... John RA (April 1995). "Pyridoxal phosphate-dependent enzymes". Biochimica et Biophysica Acta (BBA) - Protein Structure and ... Alexander FW, Sandmeier E, Mehta PK, Christen P (February 1994). "Evolutionary relationships among pyridoxal-5'-phosphate- ...
Arginine decarboxylase
The process consumes a proton in the decarboxylation and employs a pyridoxal-5'-phosphate (PLP) cofactor, similar to other ... John RA (April 1995). "Pyridoxal phosphate-dependent enzymes". Biochimica et Biophysica Acta (BBA) - Protein Structure and ... EC 4.1.1, Pyridoxal phosphate enzymes, Enzymes of known structure). ... Toney MD (January 2005). "Reaction specificity in pyridoxal phosphate enzymes". Archives of Biochemistry and Biophysics. 433 (1 ...
Pyridoxine 5'-phosphate synthase
pdxJ plays a role in the DXP-dependent pathway of pyridoxal phosphate. The DXP-dependent pathway is found predominantly in ... Mukherjee T, Hanes J, Tews I, Ealick SE, Begley TP (November 2011). "Pyridoxal phosphate: biosynthesis and catabolism". ... Mittenhuber G (January 2001). "Phylogenetic analyses and comparative genomics of vitamin B6 (pyridoxine) and pyridoxal ... a vitamer of pyridoxal phosphate). In the first step of this condensation reaction, the amine group of HAP forms a Schiff base ...
4-pyridoxolactonase
Pyridoxal dehydrogenase and 4-pyridoxolactonase". J. Biol. Chem. 244 (10): 2585-9. PMID 4306030. Portal: Biology v t e ( ...
Acetylornithine transaminase
It employs one cofactor, pyridoxal phosphate. As of late 2007, 6 structures have been solved for this class of enzymes, with ... Portal: Biology v t e (Articles with short description, Short description matches Wikidata, EC 2.6.1, Pyridoxal phosphate ...
Beta-alanine-pyruvate transaminase
Portal: Biology v t e (Articles with short description, Short description is different from Wikidata, EC 2.6.1, Pyridoxal ... It employs one cofactor, pyridoxal phosphate. HAYAISHI O, NISHIZUKA Y, TATIBANA M, TAKESHITA M, KUNO S (1961). "Enzymatic ...
Asparagine-oxo-acid transaminase
Portal: Biology v t e (EC 2.6.1, Pyridoxal phosphate enzymes, Enzymes of unknown structure, All stub articles, EC 2.6 stubs). ... It employs one cofactor, pyridoxal phosphate. MEISTER A, FRASER PE (1954). "Enzymatic formation of L-asparagine by ...
Adenosylmethionine-8-amino-7-oxononanoate transaminase
Portal: Biology v t e (EC 2.6.1, Pyridoxal phosphate enzymes, Enzymes of known structure, All stub articles, EC 2.6 stubs). ... It employs one cofactor, pyridoxal phosphate. As of late 2007, 11 structures have been solved for this class of enzymes, with ...
L-seryl-tRNASec selenium transferase
Portal: Biology v t e (EC 2.9.1, Pyridoxal phosphate enzymes, Enzymes of unknown structure, All stub articles, Transferase ... It employs one cofactor, pyridoxal phosphate. Forchhammer K, Bock A (1991). "Selenocysteine synthase from Escherichia coli. ...
Threonine aldolase
It employs one cofactor, pyridoxal phosphate. As of late 2007, 5 structures have been solved for this class of enzymes, with ... Portal: Biology v t e (Protein pages needing a picture, Genes on human chromosome 17, EC 4.1.2, Pyridoxal phosphate enzymes, ...
5-aminovalerate transaminase
It employs one cofactor, pyridoxal phosphate. Ichihara A, Ichihara EA, Suda M (1960). "Metabolism of L-lysine by bacterial ... Portal: Biology v t e (Articles with short description, Short description matches Wikidata, EC 2.6.1, Pyridoxal phosphate ...
D-amino-acid transaminase
Portal: Biology v t e (EC 2.6.1, Pyridoxal phosphate enzymes, Enzymes of known structure, All stub articles, EC 2.6 stubs). ... It employs one cofactor, pyridoxal phosphate. As of late 2007, 8 structures have been solved for this class of enzymes, with ...
Aminobenzoate decarboxylase
Portal: Biology v t e (EC 4.1.1, Pyridoxal phosphate enzymes, Enzymes of unknown structure, All stub articles, EC 4.1 stubs). ... The systematic name of this enzyme class is aminobenzoate carboxy-lyase (aniline-forming). It employs one cofactor, pyridoxal ...