Protoporphyrin IX
... contains a porphine core, a tetrapyrrole macrocycle with a marked aromatic character. Protoporphyrin IX is ... the enzyme magnesium chelatase converts it into Mg-protoporphyrin IX. Protoporphyrin IX reacts with iron salts in air to give ... which is oxidized to protoporphyrin IX. The last step is mediated by the enzyme protoporphyrinogen oxidase. Protoporphyrin IX ... Protoporphyrin IX is an organic compound, classified as a porphyrin, that plays an important role in living organisms as a ...
Zinc protoporphyrin
... (ZPP) refers to coordination complexes of zinc and protoporphyrin IX. It is a red-purple solid that is ... Measurement of zinc protoporphyrin in red cells has been used for screening for lead poisoning. and for iron deficiency. Zinc ... Verschoor M, Herber R, Zielhuis R, Wibowo A (1987). "Zinc protoporphyrin as an indicator of lead exposure: precision of zinc ... Wang S, Hannafon BN, Lind SE, Ding WQ (2015-05-22). Tan M (ed.). "Zinc Protoporphyrin Suppresses β-Catenin Protein Expression ...
Magnesium protoporphyrin IX methyltransferase
... magnesium protoporphyrin IX ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + magnesium protoporphyrin IX 13- ... In enzymology, a magnesium protoporphyrin IX methyltransferase (EC 2.1.1.11) is an enzyme that catalyzes the chemical reaction ... The systematic name of this enzyme class is S-adenosyl-L-methionine:magnesium-protoporphyrin-IX O-methyltransferase. This ... 4. S-ADENOSYLMETHIONINEMAGNESIUM PROTOPORPHYRIN METHYLTRANSFERASE". Biochem. J. 88: 325-34. PMC 1202116. PMID 14063871. ...
Magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + 2 H2O (1c) 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + ... 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + H2O (1b) 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ... Magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase (EC 1.14.13.81), is an enzyme with systematic name magnesium- ... It is therefore more accurate to show the individual steps as follows: (1a) magnesium-protoporphyrin IX 13-monomethyl ester + 2 ...
Urine test strip
... protoporphyrin and protein. The system's cells convert the protoporphyrin into unconjugated bilirubin that passes through the ...
Porphyrinogen
Protoporphyrinogen IX, precursor to protoporphyrin IX. A variety of synthetic porphyrinogens have been produced and studied in ...
Chlorophyll b
Willows, Robert D. (2003). "Biosynthesis of chlorophylls from protoporphyrin IX". Natural Product Reports. 20 (6): 327-341. doi ... forming protoporphyrin IX. Chlorophyll synthase is the enzyme that completes the biosynthesis of chlorophyll b by catalysing ...
Magnesium chelatase
... protoporphyrin IX Mg-chelatase, magnesium-protoporphyrin IX chelatase, magnesium-protoporphyrin chelatase, magnesium-chelatase ... Mg-protoporphyrin IX + 2 H+ The four substrates of this enzyme are ATP, protoporphyrin IX, Mg2+, and H2O; its four products are ... Magnesium-chelatase is a three-component enzyme (EC 6.6.1.1) that catalyses the insertion of Mg2+ into protoporphyrin IX. This ... The systematic name of this enzyme class is Mg-protoporphyrin IX magnesium-lyase. Other names in common use include ...
Coproporphyrinogen III oxidase
Sano S, Granick S (April 1961). "Mitochondrial coproporphyrinogen oxidase and protoporphyrin formation". The Journal of ...
Chlorophyllide-a oxygenase
Willows, Robert D. (2003). "Biosynthesis of chlorophylls from protoporphyrin IX". Natural Product Reports. 20 (6): 327-341. doi ...
Protochlorophyllide reductase
Willows, Robert D. (2003). "Biosynthesis of chlorophylls from protoporphyrin IX". Natural Product Reports. 20 (6): 327-341. doi ...
Chlorophyll synthase
Willows RD (June 2003). "Biosynthesis of chlorophylls from protoporphyrin IX". Natural Product Reports. 20 (3): 327-341. doi: ...
Protochlorophyllide
KEGG compound database entry [1] Willows, Robert D. (2003). "Biosynthesis of chlorophylls from protoporphyrin IX". Natural ...
Chlorophyll
Willows RD (June 2003). "Biosynthesis of chlorophylls from protoporphyrin IX". Natural Product Reports. 20 (3): 327-41. doi: ...
Chlorophyllide a reductase
Willows RD (June 2003). "Biosynthesis of chlorophylls from protoporphyrin IX". Natural Product Reports. 20 (3): 327-41. doi: ...
Chlorophyll a
Willows, Robert D. (2003). "Biosynthesis of chlorophylls from protoporphyrin IX". Natural Product Reports. 20 (6): 327-341. doi ... forming protoporphyrin IX. Chlorophyll synthase is the enzyme that completes the biosynthesis of chlorophyll a by catalysing ...
Chlorophyllide
... which is oxidised to the fully aromatic protoporphyrin IX. Insertion of iron into protoporphyrin IX in for example mammals ... The metal is inserted into protoporphyrin IX by the enzyme magnesium chelatase which catalyzes the reaction EC 6.6.1.1 ... Bollivar DW, Beale SI (September 1996). "The Chlorophyll Biosynthetic Enzyme Mg-Protoporphyrin IX Monomethyl Ester (Oxidative) ... Willows, Robert D. (2003). "Biosynthesis of chlorophylls from protoporphyrin IX". Natural Product Reports. 20 (6): 327-341. doi ...
Bacteriochlorophyll
Willows, Robert D. (2003). "Biosynthesis of chlorophylls from protoporphyrin IX". Natural Product Reports. 20 (6): 327-341. doi ...
Divinyl chlorophyllide a 8-vinyl-reductase
Willows, Robert D. (2003). "Biosynthesis of chlorophylls from protoporphyrin IX". Natural Product Reports. 20 (6): 327-341. doi ...
Erythropoietic porphyria
Levels of free protoporphyrin decreased significantly as there was iron available for the FECH to produce heme. Levels of zinc- ... Because there is a buildup of protoporphyrin IX with no malfunction of the FECH enzyme, all the available Fe2+ is used in the ... XDEPP is characterized by a buildup of protoporphyrin IX caused by in increased level of function in the ALAS2 enzyme. ... protoporphyrin, however did not decrease. X-linked sideroblastic anemia or "X-linked dominant erythropoietic protoporphyria", ...
Protoporphyrinogen IX
It is a direct precursor of protoporphyrin IX. The compound is a porphyrinogen, meaning that it has a non-aromatic ... By the action of protoporphyrinogen oxidase, protoporphyrinogen IX is later converted into protoporphyrin IX, the first colored ...
Porphyrin
Simplified view of heme, a complex of a protoporphyrin IX. A geoporphyrin, also known as a petroporphyrin, is a porphyrin of ... Octaethylporphyrin (H2OEP) is a synthetic analogue of protoporphyrin IX. Unlike the natural porphyrin ligands, OEP2− is highly ... Representative porphyrins and derivatives Derivatives of protoporphyrin IX are common in nature, the precursor to hemes. ... Tetraphenylporphyrin (H2TPP)is another synthetic analogue of protoporphyrin IX. Unlike the natural porphyrin ligands, TPP2− is ...
Porphine
Many porphyrins are found in nature with the dominant example being protoporphyrin IX. Many synthetic porphyrins are also known ... Common porphyrins Derivatives of protoporphyrin IX are common in nature, the precursor to hemes. Octaethylporphyrin (H2OEP) is ... Tetraphenylporphyrin (H2TPP)is another synthetic analogue of protoporphyrin IX. Unlike the natural porphyrin ligands, TPP2− is ... a synthetic analogue of protoporphyrin IX. Unlike the natural porphyrin ligands, OEP2− is highly symmetrical. ...
Carol Remmer Angle
Angle, C. R.; Kuntzelman, D. R. (1989). "Increased erythrocyte protoporphyrins and blood lead-a pilot study of childhood growth ...
Parent structure
Protoporphyrin IX is a natural derivative of the parent porphine. Octaethylporphyrin is a synthetic derivative of the parent ...
Liquid biopsy
For example, isolation of protoporphyrin IX from blood samples can be used as a diagnostic tool for atherosclerosis. Cancer ... "Liquid biopsy of atherosclerosis using protoporphyrin IX as a biomarker". The Analyst. 139 (6): 1383-8. Bibcode:2014Ana... ...
Heme oxygenase
In most cases, HMOX selectively cleaves heme (iron protoporphyrin IX) at the α-methine bridge. The resulting bilirubin contains ... HMOX1 is inhibited by certain porphyrins such as zinc protoporphyrin. HMOX is involved in numerous cellular operations. The ... see protoporphyrin IX for further information on the Fischer nomenclature system). Drosophila melanogaster contains a unique ... the suffix IXα to identify the composition of its structure by indicating its parent molecule was protoporphyrin IX cleaved at ...
Ferrochelatase
... protoporphyrin + Fe2+ Ferrochelatase catalyzes the insertion of ferrous iron into protoporphyrin IX in the heme biosynthesis ... Protoporphyrin ferrochelatase (EC 4.98.1.1, formerly EC 4.99.1.1, or ferrochelatase; systematic name protoheme ferro-lyase ( ... Ferrochelatase can also insert other divalent metal ions into protoporphyrin. Some ions, such as Zn+2, Ni, and Co form other ... In less than five percent of cases, accumulation of protoporphyrin in the liver results in cholestasis (blockage of bile flow ...
Methyl aminolevulinate
It is a prodrug that is metabolized to protoporphyrin IX. It is marketed as Metvix. Metvix cream is applied topically and some ...
Pulse generator
2001). "Protoporphyrin IX Occurs Naturally in Colorectal Cancers and Their Metastases". Cancer Research. 61 (3): 991-999Z. ...