Proto-oncogene tyrosine-protein kinase Src
There are 9 members of the Src family kinases: c-Src, Yes, Fyn, Fgr, Yrk, Lyn, Blk, Hck, and Lck. The expression of these Src ... Proto-oncogene tyrosine-protein kinase Src, also known as proto-oncogene c-Src, or simply c-Src (cellular Src; pronounced "sarc ... Proto-oncogene tyrosine-protein kinase Src) at the PDBe-KB. Portal: Biology (Articles with short description, Short description ... This proto-oncogene may play a role in the regulation of embryonic development and cell growth. When src is activated, it ...
CBL (gene)
"The proto-oncogene p120(Cbl) is a downstream substrate of the Hck protein-tyrosine kinase". Biochem. Biophys. Res. Commun. 257 ... "Membrane-anchored Cbl suppresses Hck protein-tyrosine kinase mediated cellular transformation". Oncogene. 21 (11): 1707-16. doi ... "The adapter type protein CMS/CD2AP binds to the proto-oncogenic protein c-Cbl through a tyrosine phosphorylation-regulated Src ... "The protein product of the c-cbl protooncogene is the 120-kDa tyrosine-phosphorylated protein in Jurkat cells activated via the ...
HCK
"The proto-oncogene p120(Cbl) is a downstream substrate of the Hck protein-tyrosine kinase". Biochemical and Biophysical ... Tyrosine-protein kinase HCK is an enzyme that in humans is encoded by the HCK gene. The protein encoded by this gene is a ... "Human protein-tyrosine kinase gene HCK: expression and structural analysis of the promoter region". Oncogene. 7 (5): 849-58. ... "Membrane-anchored Cbl suppresses Hck protein-tyrosine kinase mediated cellular transformation". Oncogene. 21 (11): 1707-16. doi ...
WD Repeat and Coiled Coil Containing Protein
Proto-oncogene associated with osteosarcomas. ETS1: Aids in pathogen and tumor defense. E2F6: Associated with the oncogenic ... WDCP has known interactions with HCK, where a proline-rich region of WDCP binds to the Src homology 3 domain of HCK. As ... SUMOylation can affect protein-protein interactions and affect protein ubiquitination. Palmitoylation is the addition of a ... Table 3. Table of WDCP protein Isoforms and Protein Information. The secondary structure of WDCP Protein Isoform 1 consists of ...
BCR (gene)
The BCR protein has been shown to interact with: Abl gene, CD117, CRKL FES, Grb2, GRB10, HCK, MLLT4, PXN, PIK3CG, PTPN6, PTPRT( ... "Regulation of Bcr-Abl-induced SAP kinase activity and transformation by the SHPTP1 protein tyrosine phosphatase". Oncogene. 17 ... "p210BCR/ABL induces formation of complexes containing focal adhesion proteins and the protooncogene product p120c-Cbl". ... The breakpoint cluster region protein (BCR) also known as renal carcinoma antigen NY-REN-26 is a protein that in humans is ...
List of MeSH codes (D12.776)
... proto-oncogene proteins c-fyn MeSH D12.776.624.664.700.181 - proto-oncogene proteins c-hck MeSH D12.776.624.664.700.182 - proto ... proto-oncogene proteins c-abl MeSH D12.776.624.664.700.168 - proto-oncogene proteins c-akt MeSH D12.776.624.664.700.169 - proto ... proto-oncogene proteins c-bcr MeSH D12.776.624.664.700.172 - proto-oncogene proteins c-cbl MeSH D12.776.624.664.700.174 - proto ... proto-oncogene proteins c-kit MeSH D12.776.624.664.700.184 - proto-oncogene proteins c-maf MeSH D12.776.624.664.700.185 - proto ...
List of MeSH codes (D08)
... proto-oncogene proteins c-fyn MeSH D08.811.913.696.620.682.725.800.590 - proto-oncogene proteins c-hck MeSH D08.811.913.696. ... proto-oncogene proteins c-cbl MeSH D08.811.464.938.750.562 - proto-oncogene proteins c-mdm2 MeSH D08.811.464.938.750.750 - skp ... proto-oncogene proteins b-raf MeSH D08.811.913.696.620.682.700.559.842.500 - proto-oncogene proteins c-raf MeSH D08.811.913.696 ... proto-oncogene proteins c-akt MeSH D08.811.913.696.620.682.700.759 - proto-oncogene proteins c-bcr MeSH D08.811.913.696.620.682 ...
GRB2
RET proto-oncogene, SH2B1, SH3KBP1, SHC1, SOS1, Src, Syk, TNK2, TrkA, VAV1, VAV2, VAV3, and Wiskott-Aldrich syndrome protein. ... Warmuth M, Bergmann M, Priess A, Häuslmann K, Emmerich B, Hallek M (December 1997). "The Src family kinase Hck interacts with ... "The protein product of the c-cbl protooncogene is the 120-kDa tyrosine-phosphorylated protein in Jurkat cells activated via the ... SH3 domain-mediated protein-protein interaction blocking drug". Oncogene. 21 (13): 2037-50. doi:10.1038/sj.onc.1205271. PMID ...
Tyrosine kinase
This growth factor receptor is called c-kit and is produced by a proto-oncogene (c-kit). Mutation of c-kit causes the ... Tyrosine-protein kinase HCK) at the PDBe-KB. Overview of all the structural information available in the PDB for UniProt: ... Tyrosine Phosphate ATP Protein tyrosine kinase proteins contain a Protein kinase domain, which consists of an N-terminal lobe ... Protein tyrosine kinase plays a role in this task, too. A protein tyrosine kinase called pp125, also referred to as focal ...
ABL (gene)
The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell ... Warmuth M, Bergmann M, Priess A, Häuslmann K, Emmerich B, Hallek M (December 1997). "The Src family kinase Hck interacts with ... Activity of ABL1 protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene ... Tyrosine-protein kinase ABL1 also known as ABL1 is a protein that, in humans, is encoded by the ABL1 gene (previous symbol ABL ...
Src family kinase
Proto-oncogene tyrosine-protein kinase Src Myristoylation SH2 domain SH3 domain Parsons SJ, Parsons JT (October 2004). "Src ... Hck, Blk, and Lyn in the SrcB subfamily, and Frk in its own subfamily. Frk has homologs in invertebrates such as flies and ... It allows for weak protein-protein and protein-lipid interactions. Myristoylation aids in the membrane association of Src ... Src family kinases interact with many cellular cytosolic, nuclear and membrane proteins, modifying these proteins by ...