Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a cytoplasmatic protein encoded by gene PTPN22 and a member of ... Tyrosine-protein phosphatase non-receptor type 22) at the PDBe-KB. (Articles with short description, Short description matches ... "Association of inhibitory tyrosine protein kinase p50csk with protein tyrosine phosphatase PEP in T cells and other hemopoietic ... PEST family of protein tyrosine phosphatases. This protein is also called "PEST-domain Enriched Phosphatase" ("PEP") or " ...

... thyrotropin receptor, protein tyrosine phosphatase nonreceptor type 22 (PTPN22), and cytotoxic T-lymphocyte-associated antigen ... Other types may not stimulate the thyroid gland, but prevent TSI and TSH from binding to and stimulating the receptor. Another ... The three types of autoantibodies to the TSH receptor currently recognized are: Thyroid stimulating immunoglobulins: these ... in which the body produces antibodies that are specific to a self-protein - the receptor for thyroid-stimulating hormone. ( ...

In addition to HLA-DR, the protein tyrosine phosphatase, non-receptor type 22 (lymphoid) (1p13.2 - PTPN22), "CT/TT" genotype ... 2006). "Association of the protein tyrosine phosphatase, non-receptor type 8 R620W polymorphism with anti-topoisomerase I- and ... also called anti-topoisomerase I after the type I topoisomerase target) is a type of antinuclear autoantibody seen mainly in ... Diseases with ATA are autoimmune disease because they react with self-proteins. They are also referred to as anti-DNA ...

... into 38 classical PTPs 21 receptor tyrosine phosphatases 17 nonreceptor-type PTPs 61 VH-1-like or dual-specific phosphatases ( ... "The crystal structure of human receptor protein tyrosine phosphatase kappa phosphatase domain 1". Protein Sci. 15 (6): 1500- ... a protein]-tyrosine phosphate + H2O = [a protein]-tyrosine + phosphate Protein tyrosine (pTyr) phosphorylation is a common post ... Protein tyrosine phosphatases (EC 3.1.3.48, systematic name protein-tyrosine-phosphate phosphohydrolase) are a group of enzymes ...

"Receptor-type protein-tyrosine phosphatase-kappa regulates epidermal growth factor receptor function". J Biol Chem. 280 (52): ... The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Protein tyrosine phosphatases ... Receptor-type tyrosine-protein phosphatase kappa is an enzyme that in humans is encoded by the PTPRK gene. PTPRK is also known ... "Entrez Gene: PTPRK protein tyrosine phosphatase, receptor type, K". {{cite web}}: Missing or empty ,url= (help) Zhang Y, ...

Tyrosine-protein phosphatase non-receptor type 1 also known as protein-tyrosine phosphatase 1B (PTP1B) is an enzyme that is the ... "Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible ... Receptor Kinase Activity by Protein Tyrosine Phosphatase 1B (PTP-1B) and Enhanced IGF-I-Mediated Suppression of Apoptosis and ... "Protein tyrosine phosphatase 1B interacts with the activated insulin receptor". Diabetes. 45 (10): 1379-85. doi:10.2337/ ...

"A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome". Molecular Cell. 65 (2): 347-360. doi: ... Zinc finger CCHC-type containing 18 (ZCCHC18) is a protein that in humans is encoded by ZCCHC18 gene. It is also known as Smad- ... to map the PPIs between human receptor tyrosine kinases (RTKs) and phosphatases. By examining RNA-seq data from The Cancer ... While interrogating 4440 tumor samples from 15 cancer types from TCGA, the analysis showed a vary protein mutation frequency in ...

Receptor-type tyrosine-protein phosphatase mu is an enzyme that in humans is encoded by the PTPRM gene. The protein encoded by ... Protein tyrosine phosphatases are protein enzymes that remove phosphate moieties from tyrosine residues on other proteins. ... "Entrez Gene: PTPRM protein tyrosine phosphatase, receptor type, M". Tonks NK, Yang Q, Flint AJ, Gebbink MF, Franza BR, Hill DE ... "Receptor protein tyrosine phosphatases, cell adhesion and signal transduction". Advances in Protein Phosphatases. 8: 241-71. ...

"Phosphorylation-dependent regulation of Kv2.1 Channel activity at tyrosine 124 by Src and by protein-tyrosine phosphatase ... The type of pore domain (number of subunits) determines if the channel has the typical 6 transmembrane (protein) spanning ... These channels can also act as effectors in downstream signaling in G-protein coupled receptor transduction. KCNB1's regulation ... channels in mice lacking protein tyrosine phosphatase epsilon". The EMBO Journal. 19 (15): 4036-45. doi:10.1093/emboj/19.15. ...

... receptor tyrosine phosphatase family and encodes a single-pass type I membrane protein with two cytoplasmic tyrosine-protein ... Receptor-type tyrosine-protein phosphatase zeta also known as phosphacan is an enzyme that in humans is encoded by the PTPRZ1 ... "Entrez Gene: PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1". Krueger NX, Saito H (1992). "A human ... "Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases ...

April 2022). "Protein tyrosine phosphatase receptor δ serves as the orexigenic asprosin receptor". Cell Metabolism. 34 (4): 549 ... There has been evidence connecting asprosin secretion from wild-type human dermal fibroblasts suggesting that it may be ... Asprosin's orexigenic effects are mediated through binding to protein tyrosine phosphatase receptor delta (PTPRD). Genetic ... The first indication that asprosin was in fact a cerebrospinal fluid (CSF) protein, in addition to being a plasma protein, was ...

... a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer". Science. 275 (5308): 1943- ... Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R (Dec 1993). "A C. elegans mutant that lives twice as long as wild type". ... Schuur ER, Loktev AV, Sharma M, Sun Z, Roth RA, Weigel RJ (2001). "Ligand-dependent interaction of estrogen receptor-alpha with ... Forkhead box protein O4 is a protein that in humans is encoded by the FOXO4 gene. FOXO4 is a member of the forkhead family ...

Smad target gene protein tyrosine phosphatase receptor type kappa is required for TGF-{beta} function". Molecular and Cellular ... Tiganis T (January 2002). "Protein tyrosine phosphatases: dephosphorylating the epidermal growth factor receptor". IUBMB Life. ... mediates binding of the protein-tyrosine phosphatase SHP-1 to the epidermal growth factor receptor and attenuation of receptor ... "Association of SH2 domain protein tyrosine phosphatases with the epidermal growth factor receptor in human tumor cells. ...

Protein tyrosine phosphatase (PTP), non-receptor type 5, also known as STEP (STriatal-Enriched protein tyrosine Phosphatase), ... "Entrez Gene: PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)". Li X, Luna J, Lombroso PJ, Francke U ... Protein tyrosine phosphatase non-receptor type 5 is an enzyme that in humans is encoded by the PTPN5 gene. ... "Molecular cloning of a novel receptor-type protein tyrosine phosphatase from murine fetal liver". Gene. 194 (2): 241-7. doi: ...

Receptor-type tyrosine-protein phosphatase PCP-2 (also known as PTP-pi, PTP lambda, hPTP-J, PTPRO and PTP psi), is an enzyme ... "Entrez Gene: PTPRU protein tyrosine phosphatase, receptor type, U". Crossland S, Smith PD, Crompton MR (1996). "Molecular ... "Characterization of the adhesive properties of the type IIb subfamily receptor protein tyrosine phosphatases". Cell Commun ... "Involvement of beta3A subunit of adaptor protein-3 in intracellular trafficking of receptor-like protein tyrosine phosphatase ...

Xu X, Hong Y, Kong C, Xu L, Tan J, Liang Q, Huang B, Lu J (2008). "Protein tyrosine phosphatase receptor-type O (PTPRO) is co- ... Zhuo de X, Niu XH, Chen YC, Xin DQ, Guo YL, Mao ZB (2010). "Vitamin D3 up-regulated protein 1(VDUP1) is regulated by FOXO3A and ... Tran U, Zakin L, Schweickert A, Agrawal R, Döger R, Blum M, De Robertis EM, Wessely O (2010). "The RNA-binding protein bicaudal ... The oncogenic potential of these non-protein encoding genes was first identified in mouse viral tumorigenesis screens. In ...

Protein tyrosine phosphatase non-receptor type 7 is an enzyme that in humans is encoded by the PTPN7 gene. The protein encoded ... "Entrez Gene: PTPN7 protein tyrosine phosphatase, non-receptor type 7". Pettiford SM, Herbst R (February 2000). "The MAP-kinase ... receptors in rat basophilic leukemia 2H3 cells induces tyrosine phosphorylation of the cytosolic protein-tyrosine phosphatase ... protein-tyrosine phosphatase, nonreceptor-type 11) mutations in seven Japanese patients with Noonan syndrome". J. Clin. ...

... cytoskeletal-associated protein that binds a PEST-type protein-tyrosine phosphatase". J. Biol. Chem. 273 (46): 30487-96. doi: ... 1997). "Wiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor ... Banin S, Gout I, Brickell P (1999). "Interaction between Wiskott-Aldrich Syndrome protein (WASP) and the Fyn protein-tyrosine ... Bear JE, Rawls JF, Saxe CL (1998). "SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late ...

"Receptor protein tyrosine phosphatase alpha participates in the m1 muscarinic acetylcholine receptor-dependent regulation of ... This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed ... "Receptor protein tyrosine phosphatase alpha participates in the m1 muscarinic acetylcholine receptor-dependent regulation of ... "Tyrosine phosphorylation of Kv1.2 modulates its interaction with the actin-binding protein cortactin". The Journal of ...

"Intracellular substrates of brain-enriched receptor protein tyrosine phosphatase rho (RPTPrho/PTPRT)". Brain Research. 1116 (1 ... Marcozzi C, Burdett ID, Buxton RS, Magee AI (February 1998). "Coexpression of both types of desmosomal cadherin and plakoglobin ... The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus ... Desmoglein-1 is a protein that in humans is encoded by the DSG1 gene. Desmoglein-1 is expressed everywhere in the skin ...

December 1999). "HCPTPA, a protein tyrosine phosphatase that regulates vascular endothelial growth factor receptor-mediated ... and expression of human red cell-type acid phosphatase, a cytoplasmic phosphotyrosyl protein phosphatase". The Journal of ... It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein ... April 2016). "Low-Molecular-Weight Protein Tyrosine Phosphatase Predicts Prostate Cancer Outcome by Increasing the Metastatic ...

Wu DW, Stark KC, Dunnington D, Dillon SB, Yi T, Jones C, Pelus LM (February 2000). "SH2-Containing protein tyrosine phosphatase ... It is a member of the Janus kinase family and has been implicated in signaling by members of the type II cytokine receptor ... "Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1". ... the GM-CSF receptor family (IL-3R, IL-5R and GM-CSF-R), the gp130 receptor family (e.g., IL-6R), and the single chain receptors ...

Tyrosine-protein phosphatase non-receptor type 6, also known as Src homology region 2 domain-containing phosphatase-1 (SHP-1), ... "Entrez Gene: PTPN6 protein tyrosine phosphatase, non-receptor type 6". Amin S, Kumar A, Nilchi L, Wright K, Kozlowski M (August ... "Specific dephosphorylation of the Lck tyrosine protein kinase at Tyr-394 by the SHP-1 protein-tyrosine phosphatase". J. Biol. ... The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling ...

Kinases phosphorylate proteins and phosphatases dephosphorylate proteins. Many enzymes and receptors are switched "on" or "off ... tyrosine and histidine residues in eukaryotic proteins. Histidine phosphorylation of eukaryotic proteins appears to be much ... Because of the ease with which proteins can be phosphorylated and dephosphorylated, this type of modification is a flexible ... In prokaryotic proteins phosphorylation occurs on the serine, threonine, tyrosine, histidine or arginine or lysine residues. ...

Kinases phosphorylate proteins and phosphatases dephosphorylate proteins. Many enzymes and receptors are switched "on" or "off ... tyrosine and histidine residues in eukaryotic proteins. Histidine phosphorylation of eukaryotic proteins appears to be much ... Because of the ease with which proteins can be phosphorylated and dephosphorylated, this type of modification is a flexible ... In prokaryotic proteins phosphorylation occurs on the serine, threonine, tyrosine, histidine or arginine or lysine residues. ...

Kinases phosphorylate proteins and phosphatases dephosphorylate proteins. Many enzymes and receptors are switched "on" or "off ... tyrosine and histidine residues in eukaryotic proteins. Histidine phosphorylation of eukaryotic proteins appears to be much ... Because of the ease with which proteins can be phosphorylated and dephosphorylated, this type of modification is a flexible ... In prokaryotic proteins phosphorylation occurs on the serine, threonine, tyrosine, histidine or arginine or lysine residues. ...

Receptor-type tyrosine-protein phosphatase F is an enzyme that, in humans, is encoded by the PTPRF gene. The protein encoded by ... "Entrez Gene: PTPRF protein tyrosine phosphatase, receptor type, F". Bonvini P, An WG, Rosolen A, Nguyen P, Trepel J, Garcia de ... "Modulation of insulin signal transduction by eutopic overexpression of the receptor-type protein-tyrosine phosphatase LAR". Mol ... "Insulin receptor protein-tyrosine phosphatases. Leukocyte common antigen-related phosphatase rapidly deactivates the insulin ...

Receptor-type tyrosine-protein phosphatase H is an enzyme that in humans is encoded by the PTPRH gene. The protein encoded by ... "Entrez Gene: PTPRH protein tyrosine phosphatase, receptor type, H". Noguchi T, Tsuda M, Takeda H, et al. (2001). "Inhibition of ... 2004). "Identification of protein tyrosine phosphatases with specificity for the ligand-activated growth hormone receptor". Mol ... 2001). "Gene for the human transmembrane-type protein tyrosine phosphatase H (PTPRH): genomic structure, fine-mapping and its ...

Kinases phosphorylate proteins and phosphatases dephosphorylate proteins. Many enzymes and receptors are switched "on" or "off ... The name of this modification indicates the protein phosphorylation of tyrosine 41 on histone H3 protein subunit: The addition ... Because of the ease with which proteins can be phosphorylated and dephosphorylated, this type of modification is a flexible ... tyrosine and histidine residues in eukaryotic proteins. Histidine phosphorylation of eukaryotic proteins appears to be much ...

Kinases phosphorylate proteins and phosphatases dephosphorylate proteins. Many enzymes and receptors are switched "on" or "off ... tyrosine and histidine residues in eukaryotic proteins. Histidine phosphorylation of eukaryotic proteins appears to be much ... Because of the ease with which proteins can be phosphorylated and dephosphorylated, this type of modification is a flexible ... In prokaryotic proteins phosphorylation occurs on the serine, threonine, tyrosine, histidine or arginine or lysine residues. ...