Polyglutamic acid
... (PGA) is a polymer of the amino acid glutamic acid (GA). Depending on where the individual monomers connect, ... Because the glutamic acid has a chiral center, both forms of PGA can be made from L-glutamic acid, D-glutamic acid, or a ... Johnson, Leah C.; Akinmola, Adekunle Titus; Scholz, Carmen (March 2022). "Poly(glutamic acid): From natto to drug delivery ... Bhattacharyya, D (April 1998). "Novel poly-glutamic acid functionalized microfiltration membranes for sorption of heavy metals ...
Discrepin
... contains 38 amino acid residues. It has a polyglutamic acid at its N-terminal region. Discrepin has the α and β folds ... The α-helix is formed from amino acid Ser11 until Arg21. The three antiparallel β-sheets are formed from amino acid Ile2 until ... The first five toxins of this subfamily are very much alike, but discrepin only shares 50% amino acid homology with other ...
Gated drug delivery systems
"Polyglutamic Acid-Gated Mesoporous Silica Nanoparticles for Enzyme-Controlled Drug Delivery". Langmuir. 32 (33): 8507-8515. doi ... One study done by the Martinez-Manez lab in Valencia, Spain aimed to generate MSNs linked to poly-l-glutamic acid (PGA) gates ... Ideas such as steroid loaded poly (lactic-co-glycolic acid), PLGA, microparticles came into existence. The next major jump came ...
Bacillus
In vivo, B. anthracis produces a polypeptide (polyglutamic acid) capsule that kills it from phagocytosis. The genera Bacillus ... The cell wall is made of teichoic and teichuronic acids. B. subtilis is the first bacterium for which the role of an actin-like ... The ability of different species to ferment in the acid, neutral, and alkaline pH ranges, combined with the presence of ... acid-soluble spore proteins from the round-spore-forming bacteria Bacillus aminovorans, Sporosarcina halophila and S. ureae". ...
SKIDA1
The poly-glutamic acid region shows more conservation, and is found abbreviated in species as distantly related from humans as ... Human SKIDA1 contains two poly-alanine regions, one poly-histidine region, and one poly-glutamic acid region. It's unknown if ... The C-termini of SKIDA1 (amino acids 844-908) and EPOP (amino acids 313-379) have 52% identity. The C-terminus of EPOP binds to ... while isoform 2 is 827 amino acids long; isoform 2 is missing amino acids 240-318 from isoform 1. Isoform 1 is predicted to ...
Polycarboxylates
Polyamino acids like polyaspartic acid and polyglutamic acid have better biodegradability but lower chelating performance than ... They are polymers of acrylic acid or copolymers of acrylic acid and maleic acid. The polymer is used as the sodium salt (see: ...
Jyoti Prakash Tamang
1. 1. Pariyar, P., Yaduvanshi, P.S., Raghu, P. and Tamang, J.P. (2022). Screening of Poly-glutamic acid (PGA)-producing ... 6. Rai, R. and Tamang, J.P. (2022). In vitro and genetic screening of probiotic properties of lactic acid bacteria isolated ... Shangpliang, H.N.K. and Tamang, J.P. (2021). Phenotypic and genotypic characterizations of lactic acid bacteria isolated from ... Pradhan, P. and Tamang, J.P. (2021). Probiotic properties of lactic acid bacteria isolated from traditionally prepared dry ...
Small-angle X-ray scattering
Leisner, Dietrich; Imae, Toyoko (2003-08-01). "Interpolyelectrolyte Complex and Coacervate Formation of Poly(glutamic acid) ...
Natrialba
The osmotic pressure and these amino acids help to control the amount of salt within the cell. For instance, N. magadii is an ... nov., a novel extremely halophilic, aerobic, non-pigmented member of the Archaea from Egypt that produces extracellular poly(glutamic ... For example, their cellular machinery is adapted to high salt concentrations by having charged amino acids on their surfaces, ... Those harsh conditions resulted in changed composition of charged amino acids in the proteins (average isoelectric point is ...
Mono-BOC-cystamine
... chelates in poly(glutamic acid) Gd-DO3A conjugates for contrast-enhanced MR imaging". Magnetic Resonance Imaging. 24 (7): 931- ...
Crenolanib
... inhibits the ability of recombinant PDGFRβ to phosphorylate a synthetic tyrosine substrate (poly-glutamic acid- ...
Owais Mohammad
Zia Q, Khan AA, Swaleha Z, Owais M. Self-assembled amphotericin B-loaded polyglutamic acid nanoparticles: preparation, ... Dinh T, Zia Q, Zubair S, Stapleton P, Singh R, Owais M, Somavarapu S. Novel biodegradable poly(gamma-glutamic acid)- ... Nanomedicine Khan AA, Jabeen M, Khan AA, Owais M. Anticancer efficacy of a novel propofol-linoleic acid-loaded escheriosomal ... Liposomes have been widely considered useful as drug/enzyme/nucleic acid vehicles in therapy. However, their successful ...
Coulomb explosion
... the electrostatic repulsion of dissociated carboxyl groups of polyglutamic acid) may be part of the explosive action of ...
Gamma-glutamyl hydrolase
... folic acid conjugase, poly(gamma-glutamic acid) endohydrolase, polyglutamate hydrolase, poly(glutamic acid) hydrolase II, ...
List of MeSH codes (D12.125)
1-carboxyglutamic acid MeSH D12.125.067.750.400 - glutamates MeSH D12.125.067.750.400.700 - polyglutamic acid MeSH D12.125. ... 1-carboxyglutamic acid MeSH D12.125.119.450.400 - glutamates MeSH D12.125.119.450.400.700 - polyglutamic acid MeSH D12.125. ... 2-aminoadipic acid MeSH D12.125.119.170 - aspartic acid MeSH D12.125.119.170.150 - d-aspartic acid MeSH D12.125.119.170.275 - ... aspartic acid MeSH D12.125.067.500.150 - d-aspartic acid MeSH D12.125.067.500.275 - isoaspartic acid MeSH D12.125.067.500.400 ...
Anthrax toxin
1). The lethality of the disease is caused by the bacterium's two principal virulence factors: (i) the polyglutamic acid ... The disordered loop in domain 2 also has a pattern of alternating hydrophobic and hydrophilic amino acids, which is a pattern ... Additional electrophysiological measurements of cysteine substitutions place the amino acids of this loop inside the lumen of ... one of which lies with a Greek-key histidine within a cluster of polar amino acids. This cluster (including the two histidines ...
Cell-penetrating peptide
... poly-glutamic acid) and the linker, which confer the proper distance between these two charged residues in order to maximize ... Most CPP-nucleic acid complexes that have been proposed so far are formed through covalent bonding. A range of CPP-nucleic acid ... charged amino acids and non-polar, hydrophobic amino acids. These two types of structures are referred to as polycationic or ... CPPs typically have an amino acid composition that either contains a high relative abundance of positively charged amino acids ...
PGA
... a chemical substance that is a metabolic intermediate in both glycolysis and the Calvin cycle Polyglutamic acid, a polymer of ... the glutamic acid (one of proteinogenic amino acids) Polyglycolic acid, another name for polyglycolide Propylene glycol ... PGA Championship New Zealand PGA Championship South African PGA Championship Indonesia PGA Championship 3-Phosphoglyceric acid ...
Anthrax
... and a polyglutamic acid capsule. Nonetheless, the Vollum strain, developed but never used as a biological weapon during the ... which contains only the anthrax toxin virulence plasmid and not the polyglutamic acid capsule expressing plasmid. Strain 836, ... peracetic acid, ozone gas, hypochlorous acid, sodium persulfate, and liquid bleach products containing sodium hypochlorite. ... The lethality of the anthrax disease is due to the bacterium's two principal virulence factors: the poly-D-glutamic acid ...
Engineered CAR T cell delivery
used poly(β-amino ester) (PBAE) particles laden with polyglutamic acid (PGA), nuclear localization signals, and T-cell ... lactic acid) (PLA) nanoparticles to form the hydrogel, then mixed CAR-T cells and IL-15 into the matrix. The sustained release ... was shown to slowly but efficiently release IL-15 and CAR-T cells from a cross-linked hyaluronic acid matrix and poly(lactic-co ... such as the hyaluronic acid hydrogel system developed by Hu et al. This system, which targets melanoma through targeting the ...