Phosphocreatine
The cell's ability to generate phosphocreatine from excess ATP during rest, as well as its use of phosphocreatine for quick ... Once inside the cells it is transformed into phosphocreatine by the enzyme complex creatine kinase. Phosphocreatine is able to ... Phosphocreatine can be broken down into creatinine, which is then excreted in the urine. A 70 kg man contains around 120 g of ... Phosphocreatine can anaerobically donate a phosphate group to ADP to form ATP during the first five to eight seconds of a ...
Fabio Cannavaro
Phosphocreatine is formed naturally within the body, with over 95% of the compound stored within the muscle cells. The body ... The substance was found to be neoton (phosphocreatine), which is used in cardiac surgery to protect the heart during periods of ... "Phosphocreatine". Faqs.org. Retrieved 7 June 2010. "Cannavaro injection video troubles Italian sports executive". Yahoo! Sports ...
Creatine phosphate shuttle
This makes conversion of creatine to phosphocreatine a highly favored reaction. Phosphocreatine is a very-high-energy compound ... Thus, phosphocreatine breaks down to creatine, giving its inorganic phosphate for ATP formation. This is done by the enzyme ... This is part of phosphocreatine metabolism. In mitochondria, Adenosine triphosphate (ATP) levels are very high as a result of ... At the onset of exercise phosphocreatine is broken down to provide ATP for muscle contraction. ATP hydrolysis results in ...
Creatine
The discovery of phosphocreatine was reported in 1927. In the 1960s, creatine kinase (CK) was shown to phosphorylate ADP using ... The typical creatine content of skeletal muscle (as both creatine and phosphocreatine) is 120 mmol per kilogram of dry muscle ... Creatine itself can be phosphorylated by creatine kinase to form phosphocreatine, which is used as an energy buffer in skeletal ... 95% of the human body's total creatine and phosphocreatine stores are found in skeletal muscle, while the remainder is ...
Creatinine
... it becomes the high-energy compound phosphocreatine. Creatine conversion to phosphocreatine is catalyzed by creatine kinase; ... Creatinine itself is produced via a biological system involving creatine, phosphocreatine (also known as creatine phosphate), ...
Fibromyalgia
Phosphocreatine is used in the phosphagen system to produce ATP. The study found that low creatine and low phosphocreatine were ... The fibromyalgia patients were found to have lower phosphocreatine (PCr) and lower creatine (Cr) than the control group. ... and phosphocreatine, and increased levels of AMP and creatine (use of creatine kinase and myokinase in the phosphagen system ... Low phosphocreatine levels may disrupt glutamate neurotransmission within the brains of those with fibromyalgia. Glutamate/ ...
Albrecht Kossel
Another was Otto Folin, an American chemist who discovered Phosphocreatine. In 1923, Kossel was honored by being named ...
P. T. Narasimhan
Mora B.; Narasimhan P.T.; Ross B.D.; Allman J.; Barker P. B. (1991). "P Saturation Transfer and Phosphocreatine Imaging in the ...
CKMT1A
Kekelidze T, Khait I, Togliatti A, Benzecry JM, Wieringa B, Holtzman D (December 2001). "Altered brain phosphocreatine and ATP ...
Altitude training
Bogdanis, GC; Nevill, ME; Boobis, LH; Lakomy, HK (1 March 1996). "Contribution of phosphocreatine and aerobic metabolism to ... Possible physiological advantages from RSH include compensatory vasodilation and regeneration of phosphocreatine (PCr). The ...
Ion chromatography
The functions of these isoenzymes are to convert creatine, using ATP, into phosphocreatine expelling ADP. Mini columns were ...
Exercise physiology
The quick energy sources consist of the phosphocreatine (PCr) system, fast glycolysis, and adenylate kinase. All of these ... This enzyme catalyzes a reaction that combines phosphocreatine and adenosine diphosphate (ADP) into ATP and creatine. This ... resource is short lasting because oxygen is required for the resynthesis of phosphocreatine via mitochondrial creatine kinase. ...
In vivo magnetic resonance spectroscopy
Adenosine triphosphate
"The Determination of Phosphorus and the Discovery of Phosphocreatine and ATP: the Work of Fiske and SubbaRow". Journal of ...
Creatinolfosfate
... not to be confused with phosphocreatine. v t e (Articles with changed EBI identifier, ECHA InfoCard ID from Wikidata, Articles ...
List of biochemists
... responsible for elucidating the role of phosphocreatine in energy production in muscles. Member Natl. Acad. Sci. USA Joseph ...
Chemotaxonomy
Generally, there are two types of phosphagens in animals, phosphoarginine (PA) in invertebrates and phosphocreatine (PC) in ...
Strength training
The increase in mean power output was attributed to creatine's ability to counteract the lack of intramuscular phosphocreatine ... such as the buildup of lactic acid and the depletion of adenosine triphosphate and phosphocreatine. Resting 3-5 minutes between ...
Bioenergetic systems
Two of the three depend upon the food eaten, whereas the other depends upon a chemical compound called phosphocreatine. The ... phosphocreatine circuit' for cellular energy homeostasis". The Biochemical Journal. 281 (Pt 1): 21-40. doi:10.1042/bj2810021. ... When the phosphagen system has been depleted of phosphocreatine (creatine phosphate), the resulting AMP produced from the ...
Sarcomere
... which facilitates the reaction of ADP and phosphocreatine into ATP and creatine. The interaction between actin and myosin ...
Isozyme
... catalyses the interconversion of phospho creatine to creatine . CPK exists in 3 isoenzymes. Each isoenzymes is a dimer of 2 ...
Creatine kinase
... (CK), also known as creatine phosphokinase (CPK) or phosphocreatine kinase, is an enzyme (EC 2.7.3.2) expressed ... CK catalyses the conversion of creatine and uses adenosine triphosphate (ATP) to create phosphocreatine (PCr) and adenosine ... While mitochondrial creatine kinase is directly involved in the formation of phosphocreatine from mitochondrial ATP, cytosolic ... Mitochondrial creatine kinase (CKm) is present in the mitochondrial intermembrane space, where it regenerates phosphocreatine ( ...
Phosphoramidate
Two examples of natural phosphoramidates are phosphocreatine and the phosphoramidate formed when histidine residues in ...
Cerebral creatine deficiency
In affected individuals with all three disorders, there is an almost complete absence of creatine and phosphocreatine in the ...
CKM (gene)
The encoded protein reversibly catalyzes the transfer of "energy-rich" phosphate between ATP and creatine and between phospho-creatine ...
Anaerobic organism
creatine + ATP ⇌ phosphocreatine + ADP + H+ The reaction is reversible as well, allowing cellular ATP levels to be maintained ...
Biology of bipolar disorder
Downregulation of genes encoding for mitochondrial subunits, decreased concentration of phosphocreatine, decreased brain pH, ...
CKB (gene)
The encoded protein reversibly catalyzes the transfer of "energy-rich" phosphate between ATP and creatine or between phospho-creatine ...
Branched-chain amino acid
... and is responsible for transferring a phosphate group from ATP to create a phosphocreatine molecule. BCAA supplementation has ...
ATP:guanido phosphotransferase family
... generating phosphocreatine and ADP. Creatine kinase plays an important role in energy metabolism of vertebrates. There are at ...