Pharmacokinetics
Clinical pharmacokinetics (arising from the clinical use of population pharmacokinetics) is the direct application to a ... Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug ... In pharmacokinetics, steady state refers to the situation where the overall intake of a drug is fairly in dynamic equilibrium ... Pharmacokinetics is often studied using mass spectrometry because of the complex nature of the matrix (often plasma or urine) ...
Compartment (pharmacokinetics)
In pharmacokinetics, a compartment is a defined volume of body fluids, typically of the human body, but also those of other ... Various multi-compartment models can be used in the areas of pharmacokinetics and pharmacology, in the support of efforts in ...
Pharmacokinetics simulation
... gives an insight to drug efficacy and safety before exposure of individuals to the new drug that ... Pharmacokinetics simulation is a simulation method used in determining the safety levels of a drug during its development. ... Pharmacokinetics simulations help in addition in therapy planning, to stay within the therapeutic range under various ...
Clinical Pharmacokinetics
... is a peer-reviewed medical journal published by Adis International (Springer Nature) that covers ... topics related to pharmacokinetics. According to the Journal Citation Reports, the journal has a 2022 Impact Factor™ of 4.5 ...
Pharmacokinetics of progesterone
The pharmacokinetics of progesterone, concerns the pharmacodynamics, pharmacokinetics, and various routes of administration of ... Pharmacodynamics of progesterone Pharmacokinetics of estradiol Pharmacodynamics of estradiol Pharmacokinetics of testosterone ... Pharmacokinetics following percutaneous administration". European Journal of Drug Metabolism and Pharmacokinetics. 23 (3): 397- ... The pharmacokinetics of progesterone are dependent on its route of administration. The medication is approved in the form of ...
Pharmacokinetics of estradiol
The pharmacokinetics of estradiol, including its bioavailability, metabolism, biological half-life, and other parameters, ... Lobo RA, Cassidenti DL (January 1992). "Pharmacokinetics of oral 17 beta-estradiol". J Reprod Med. 37 (1): 77-84. PMID 1548642 ... Stege R, Gunnarsson PO, Johansson CJ, Olsson P, Pousette A, Carlström K (May 1996). "Pharmacokinetics and testosterone ... Garza-Flores J (April 1994). "Pharmacokinetics of once-a-month injectable contraceptives". Contraception. 49 (4): 347-59. doi: ...
Pharmacokinetics of testosterone
Pharmacodynamics of estradiol Pharmacokinetics of estradiol Pharmacodynamics of progesterone Pharmacokinetics of progesterone ... The pharmacokinetics of testosterone cypionate are said to be the same as those of testosterone enanthate, with "extremely ... The pharmacokinetics of testosterone, including its bioavailability, metabolism, biological half-life, and other parameters, ... Wilson DM, Kiang TK, Ensom MH (March 2018). "Pharmacokinetics, safety, and patient acceptability of subcutaneous versus ...
Infectious Disease Pharmacokinetics Laboratory
The Infectious Disease Pharmacokinetics Laboratory (IDPL) is a research facility that is affiliated with the College of ... The Infectious Disease Pharmacokinetics Laboratory also serves as a national reference center for the determination of serum ... "Infectious Disease Pharmacokinetics Laboratory » College of Pharmacy » University of Florida". "Emerging Pathogens Institute - ...
Area under the curve (pharmacokinetics)
In the field of pharmacokinetics, the area under the curve (AUC) is the definite integral of the concentration of a drug in ... This is an example of a PK/PD model, which combines pharmacokinetics and pharmacodynamics. Cmax (pharmacology) Cmean ( ... In pharmacokinetics, bioavailability generally refers to the fraction of a drug that is absorbed systemically and is thus ... "Clinical Pharmacokinetics of Gentamicin in Various Patient Populations and Consequences for Optimal Dosing for Gram-Negative ...
Injection (medicine)
ISBN 978-1-58212-126-0. {{cite book}}: ,work= ignored (help) Fan J, de Lannoy IA (January 2014). "Pharmacokinetics". ... "Chapter 6. Absorption/Transport Mechanisms". Handbook of Basic Pharmacokinetics … Including Clinical Applications, Seventh ...
Nitrofurantoin
Conklin JD (1978). "The pharmacokinetics of nitrofurantoin and its related bioavailability". Pharmacokinetics. Antibiotics and ...
CYP2E1
p. 9 (Section 5. Pharmacokinetics). Retrieved 5 December 2015. "Verapamil: Drug information. Lexicomp". UpToDate. Retrieved ...
Zopiclone
The pharmacokinetics of zopiclone are altered by aging and are influenced by renal and hepatic functions. In severe chronic ... Viron B, De Meyer M, Le Liboux A, Frydman A, Maillard F, Mignon F, Gaillot J (April 1990). "Steady state pharmacokinetics of ... Sex and race have not been found to interact with pharmacokinetics of zopiclone. The melting point of zopiclone is 178 °C. ... The terminal elimination half-life of zopiclone ranges from 3.5 to 6.5 hours (5 hours on average). The pharmacokinetics of ...
Cmax (pharmacology)
Cavg (pharmacology) Area under the curve (pharmacokinetics) Tracy TS (2004). "Pharmacokinetics". In Stitzel RE, Craig CF (eds ... "Statistics and Pharmacokinetics in Clinical Pharmacology Studies" (PDF). Archived from the original (PDF) on 2013-11-13. Urso R ... It is a standard measurement in pharmacokinetics. Cmax is the opposite of Cmin, which is the minimum (or trough) concentration ... Blardi P, Giorgi G (March 2002). "A short introduction to pharmacokinetics". Eur Rev Med Pharmacol Sci. 6 (2-3): 33-44. PMID ...
Childbirth
Tsatsaris, Vassilis; Cabrol, Dominique; Carbonne, Bruno (2004). "Pharmacokinetics of tocolytic agents". Clinical ...
Racemization
2004). "Clinical pharmacokinetics of thalidomide". Clinical Pharmacokinetics. 43 (5): 311-327. doi:10.2165/00003088-200443050- ...
Effects of cannabis
Grotenhermen F (2003). "Pharmacokinetics and pharmacodynamics of cannabinoids". Clinical Pharmacokinetics. 42 (4): 327-60. doi: ...
Physiologically based pharmacokinetic modelling
Lutz, R.J.; Dedrick, R.L.; Tuey, D.; Sipes, G.; Anderson, M.W.; Matthews, H.B. (1984). "Comparison of the pharmacokinetics of ... Dedrick, R.L.; Forrester, D.D.; Cannon, J.N.; El Dareer, S.M.; Mellett, L.B. (1973). "Pharmacokinetics of 1-beta-D- ... Modeling inputs is necessary to come up with a meaningful description of a chemical's pharmacokinetics. The following examples ... Bogen, K.T.; Hall, L.C. (1989). "Pharmacokinetics for regulatory risk analysis: The case of 1,1,1-trichloroethane (methyl ...
Hydroxyzine
Simons FE, Simons KJ, Frith EM (January 1984). "The pharmacokinetics and antihistaminic of the H1 receptor antagonist ... Paton DM, Webster DR (1985). "Clinical pharmacokinetics of H1-receptor antagonists (the antihistamines)". Clinical ...
Hasan B. Alam
Clinical Pharmacokinetics. 57 (2): 209-219. doi:10.1007/s40262-017-0553-1. ISSN 1179-1926. PMC 5699961. PMID 28497259. "Hasan B ...
Modafinil sulfone
Robertson, P (2002). "Effect of modafinil on the pharmacokinetics of ethinyl estradiol and triazolam in healthy volunteers". ... Robertson, Philmore; Hellriegel, Edward T. (2003). "Clinical Pharmacokinetic Profile of Modafinil". Clinical Pharmacokinetics. ... "Comparison of the Single-Dose Pharmacokinetics and Tolerability of Modafinil and Dextroamphetamine Administered Alone or in ...
Primidone
An update". Clinical Pharmacokinetics. 31 (3): 198-214. doi:10.2165/00003088-199631030-00004. PMID 8877250. S2CID 22081046. ... Drug Metabolism and Pharmacokinetics. 22 (4): 276-286. doi:10.2133/dmpk.22.276. PMID 17827782. Archived from the original on ...
Bilastine
... has linear pharmacokinetics in the 2.5-220 mg dose range in healthy adult subjects without evidence of accumulation ... Clinical Pharmacokinetics. 48 (8): 543-554. doi:10.2165/11317180-000000000-00000. PMID 19705924. S2CID 552051. Church MK (2021 ...
Metformin
February 2011). "Clinical pharmacokinetics of metformin". Clinical Pharmacokinetics. 50 (2): 81-98. doi:10.2165/11534750- ... "Effect of cephalexin on the pharmacokinetics of metformin in healthy human volunteers". Drug Metabolism and Drug Interactions. ... Updates in Pharmacokinetics and Pharmacodynamics". Current Pharmaceutical Design. 23 (17): 2532-2550. doi:10.2174/ ...
Side effects of cyproterone acetate
Mahler C, Verhelst J, Denis L (May 1998). "Clinical pharmacokinetics of the antiandrogens and their efficacy in prostate cancer ... Mahler C, Verhelst J, Denis L (May 1998). "Clinical pharmacokinetics of the antiandrogens and their efficacy in prostate cancer ... ". Clinical Pharmacokinetics. 34 (5): 405-17. doi:10.2165/00003088-199834050-00005. PMID 9592622. S2CID 25200595. Chang C (22 ...
Donepezil
Clinical Pharmacokinetics. 52 (4): 225-241. doi:10.1007/s40262-013-0038-9. PMID 23408070. S2CID 1686999. "Donepezil: ...
Diazepam
Bateman DN (1986). "The action of cisapride on gastric emptying and the pharmacodynamics and pharmacokinetics of oral diazepam ... Riss J, Cloyd J, Gates J, Collins S (August 2008). "Benzodiazepines in epilepsy: pharmacology and pharmacokinetics". Acta ... Back DJ, Orme ML (June 1990). "Pharmacokinetic drug interactions with oral contraceptives". Clinical Pharmacokinetics. 18 (6): ...
Zimelidine
Clinical Pharmacokinetics. 8 (6): 530-40. doi:10.2165/00003088-198308060-00004. PMID 6228368. S2CID 42052631. Barondes, Samuel ...
Alpha-1 blocker
Franco-Salinas, Gabriela; de la Rosette, Jean J. M. C. H.; Michel, Martin C. (March 2010). "Pharmacokinetics and ... Roehrborn, C. G. (December 2001). "Alfuzosin: overview of pharmacokinetics, safety, and efficacy of a clinically uroselective ... Clinical Pharmacokinetics. 49 (3): 177-188. doi:10.2165/11317580-000000000-00000. ISSN 1179-1926. PMID 20170206. S2CID ...
Levomefolic acid
... comparison of clinical pharmacokinetics and pharmacodynamics". Clinical Pharmacokinetics. 49 (8): 535-48. doi:10.2165/11532990- ...