Peptides. 27 (4): 911-6. doi:10.1016/j.peptides.2005.12.014. PMID 16476508. Steckelings, U; Kaschina, E; Unger, T (2005). "The ... Peptides. 26 (11): 2274-9. doi:10.1016/j.peptides.2005.04.025. PMID 16137788. "Master Journal List". Intellectual Property & ... "Peptides". 2020 Journal Citation Reports. Web of Science (Science ed.). Thomson Reuters. 2021. Official website (Articles with ... Peptides is a monthly peer-reviewed scientific journal covering the biochemistry, neurochemistry, pharmacology, and biological ...
... are one of the largest families of neuropeptides, found from amphibians to mammals. They were so named due ... Tachykinin peptides are also involved in inflammation, and tachykinin receptor antagonists have been researched for use in ... The genes also code for multiple splice forms that are made up of different sets of peptides. Tachykinins excite neurons, evoke ... Neuropeptide K and neuropeptide gamma are N-terminally longer versions of neurokinin A that appear to be final peptide products ...
... are a family of short (23 amino acids) insect peptides that halt metamorphosis of insects from larvae to ... These peptides contain one disulphide bridge. The family includes growth-blocking peptide (GBP) of Mythimna separata (Oriental ... "Structure of the insect cytokine peptide plasmatocyte-spreading peptide 1 from Pseudoplusia includens". Journal of Biological ... as well as plasmatocyte-spreading peptide (PSP1). Skinner WS, Dennis PA, Li JP, Summerfelt RM, Carney RL, Quistad GB (July 1991 ...
... including antimicrobial peptides, in a protein sequence PeptideRanker Bioactive peptide, including antimicrobial peptide, ... Antimicrobial peptides (AMPs), also called host defence peptides (HDPs) are part of the innate immune response found among all ... The peptide-lipid pore complex becomes intrinsically disordered, with the orientation of the peptide not well defined. Several ... Antimicrobial peptides are generally between 12 and 50 amino acids. These peptides include two or more positively charged ...
... include: Casomorphin (from milk) Gluten exorphin (from gluten) Gliadorphin/gluteomorphin (from gluten) ... Rubiscolin (from spinach) Soymorphin-5 (from soy) Oryzatensin (from rice) v t e v t e (Peptides, Opioids, All stub articles, ...
... are a family of highly potent antimicrobial peptides with a large spectrum of activity, which ... A number of these defence peptides are secreted from the skin of frogs and other amphibians, including the opiate-like ... Conlon JM, Kolodziejek J, Nowotny N (August 2009). "Antimicrobial peptides from the skins of North American frogs". Biochimica ... Haney EF, Hunter HN, Matsuzaki K, Vogel HJ (August 2009). "Solution NMR studies of amphibian antimicrobial peptides: linking ...
The final peptides are eight to fourteen residues long. Erspamer V, Erspamer GF, Mazzanti G, Endean R (1984). "Active peptides ... Bombesin-like peptides comprise a large family of peptides which were initially isolated from amphibian skin, where they ... Bombesin-like peptides, like many other active peptides, are synthesized as larger protein precursors that are enzymatically ... In mammals and birds two categories of bombesin-like peptides are known, gastrin-releasing peptide (GRP), which stimulates the ...
In genetic engineering, the 2A peptides are used to cleave a longer peptide into two shorter peptides. The 2A peptides can be ... 2A self-cleaving peptides, or 2A peptides, is a class of 18-22 aa-long peptides, which can induce ribosomal skipping during ... resulting in the peptide located upstream of the 2A peptide to have extra amino acids on its C-terminal end while the peptide ... These peptides share a core sequence motif of DxExNPGP, and are found in a wide range of viral families. 2A peptides are used ...
... renal peptides, respiratory peptides, opioid peptides, neurotrophic peptides, and blood-brain peptides. Some ribosomal peptides ... fungal peptides, invertebrate peptides, amphibian/skin peptides, venom peptides, cancer/anticancer peptides, vaccine peptides, ... immune/inflammatory peptides, brain peptides, endocrine peptides, ingestive peptides, gastrointestinal peptides, cardiovascular ... Amylin AGG01 Aromatic short peptides Biomimetic peptides Peptide amphiphiles Peptide dendrimers B-type Natriuretic Peptide (BNP ...
... forms a peptide bond). A peptide bond can be broken by hydrolysis (the addition of water). The hydrolysis of peptide bonds in ... Peptides and proteins are chains of amino acids held together by peptide bonds (and sometimes by a few isopeptide bonds). ... However, not all peptide groups have the same effect on folding; nonnative isomers of other peptide groups may not affect ... Some peptides, like alpha-amanitin, are called ribosomal peptides as they are made by ribosomes, but many are nonribosomal ...
Opioid peptides or opiate peptides are peptides that bind to opioid receptors in the brain; opiates and opioids mimic the ... Such peptides may be produced by the body itself, for example endorphins. The effects of these peptides vary, but they all ... Exorphins include opioid food peptides like Gluten exorphin and opioid food peptides and are mostly contained in cereals and ... hemoglobin-derived opioid peptides, including hemorphin-4, valorphin, and spinorphin, among others. While not peptides, codeine ...
... has immunotoxic as well as neurotoxic properties due to different active sites of the MCD peptide. The MCD peptide ... MCD peptide is a cationic 22-amino acid residue peptide with two disulfide bridges. Although the MCD peptide sequence shows ... Buku, A (1999). "Mast cell degranulating (MCD) peptide: a prototypic peptide in allergy and inflammation". Peptides. 20 (3): ... MCD peptide is a component of bumblebee (Megabombus pennsylvanicus) venom. In addition to MCD peptide, melittin and apamin have ...
Peptides with multiple, tandem staples are sometimes referred to as stitched peptides. Among other applications, peptide ... A stapled peptide is a short peptide, typically in an alpha-helical conformation, that is constrained by a synthetic brace (" ... Beta-peptide Druggability Non-proteinogenic amino acids Peptide synthesis Peptidomimetic Peptoid Douse, CH; Maas, SJ; Thomas, ... Since this first proof of principle, peptide stapling technology has been applied to numerous peptide templates, allowing the ...
A peptide library is a tool for studying proteins. Peptide libraries typically contain a large number of peptides that have a ... This form of peptide synthesis is limited to a peptide chain length of approximately 70 amino acids, and is generally ... Large random peptide libraries are often used for the synthesis of certain peptide molecules, such as ultra-large chemical ... "Peptide Library services". www.genscript.com. Archived from the original on 2022-03-14. Retrieved 2022-07-21. Peptide library ...
... s are hormones whose molecules are peptides. Peptide hormones have shorter amino acid chain lengths than protein ... vasoactive intestinal peptide (VIP) Siddle K, Hutton JC (1991). Peptide Hormone Secretion/Peptide Hormone Action: A Practical ... Like all peptides, peptide hormones are synthesized in cells from amino acids according to mRNA transcripts, which are ... When a peptide hormone binds to a receptor on the surface of the cell, a second messenger appears in the cytoplasm, which ...
... , and its modified analog Dala1-peptide T-amide (DAPTA), a drug in clinical trials, is a short peptide derived from ... Jul 2003). "Antiviral and immunological benefits in HIV patients receiving intranasal peptide T (DAPTA)". Peptides. 24 (7): ... Peptide T has several positive effects related to HIV disease and Neuro-AIDS. A FDG-PET neuro-imaging study in an individual ... Peptide T clinical development was stopped due to the propensity of the liquid nasal spray to lose potency upon storage and ...
A peptide microarray (also commonly known as peptide chip or peptide epitope microarray) is a collection of peptides displayed ... However, peptide synthesis on chip allows the parallel synthesis of tens of thousands of peptides providing larger peptide ... Peptides are ideally covalently linked through a chemoselective bond leading to peptides with the same orientation for ... The assay principle of peptide microarrays is similar to an ELISA protocol. The peptides (up to tens of thousands in several ...
The initial peptides were successfully used to kill B-cell lymphoma cancer cells. The reference synthetic short peptide was ... Photoactivated peptides are modified natural or synthetic peptides the functions of which can be activated with light. This can ... Caged peptides which contain photocleavable protecting groups belong to irreversibly activated peptides. Reversible activation/ ... in the side chains or in the backbone of peptide templates to get the photo-controlled peptides, which can reversibly change ...
... was first discovered in 1984 by Fushiki et al. It was purified from rat bile-pancreatic juice and the peptide ... Monitor peptide is composed of 61 amino acids with a molecular weight of approximately 6500 daltons and is basic (PI = 9.0), ... Monitor peptide, also known as pancreatic secretory trypsin inhibitor I (PSTI-I) or pancreatic secretory trypsin inhibitor 61 ( ... Monitor peptide binds to intestinal epithelial cells and induces CCK-release, which enhances pancreatic secretion in the ...
Cyclic peptides in plants are synthesized via a two-step process; the translation of a linear peptide chain, and its subsequent ... Cyclic peptides can be classified according to the types of bonds that comprise the ring. Homodetic cyclic peptides, such as ... Other bicyclic peptides include echinomycin, triostin A, and Celogentin C. There are a number of bi and monocyclic peptides ... Cyclic peptides tend to be extremely resistant to the process of digestion, making them of interest to scientists working on ...
... also known as amyloid β- peptide (Aβ)17-40/42 is the peptide resulting from the α- and γ-secretase cleavage from the ... However, p3 peptide's role in these diseases is not truly known yet. There is little information related to the p3 peptides ... This confirms the absence of N-terminal domain Aβ1-16 in p3 peptides. p3 peptide generates from the 17-40 or 17-42 sequence of ... That is why p3 peptide represents the benign form of amyloid. Energy plays a very important role in p3 peptides. While Aβ ...
Peptide-based synthetic vaccines (epitope vaccines) are subunit vaccines made from peptides. The peptides mimic the epitopes of ... The peptides can be specially designed for specificity. A single peptide vaccine can be designed to have multiple epitopes to ... Gp100 peptide vaccine is studied to treat melanoma. To generate a greater in vitro CTL response, the peptide, gp100:209-217( ... IC41 is a peptide vaccine candidate against the Hepatitis C virus. It consists of five synthetic peptides along with the ...
... , also known as peptide histidine isoleucine, is a peptide which functions as a hormone. This peptide contains a ... "Differential Effects of Peptide Histidine Isoleucine (PHI) and Related Peptides on Stimulation and Suppression of Neuroblastoma ... "Peptides that Regulate Food Intake Effect of peptide histidine isoleucine on consummatory behavior in rats". American Journal ... Peptide histidine isoleucine (PHI) is part of family that plays a vital role in the cell growth rate such as in the intestine ...
Each nonribosomal peptide synthetase can synthesize only one type of peptide. Nonribosomal peptides often have cyclic and/or ... Nonribosomal peptides (NRP) are a class of peptide secondary metabolites, usually produced by microorganisms like bacteria and ... Nonribosomal peptides are synthesized by one or more specialized nonribosomal peptide-synthetase (NRPS) enzymes. The NRPS genes ... Nonribosomal peptides are synthesized by nonribosomal peptide synthetases, which, unlike the ribosomes, are independent of ...
This class of model peptides has proved useful for studying the impact of changes in lipid composition on peptide insertion. ... WALP peptides are a class of synthesized, membrane-spanning α-helices composed of tryptophan (W), alanine (A), and leucine (L) ... Following detailed experimental studies by various techniques, the WALP and related peptides have become commonly used model ... Killian, J.Antoinette (2003). "Synthetic peptides as models for intrinsic membrane proteins". FEBS Letters. 555 (1): 134-138. ...
There are three main types of natriuretic peptides: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C- ... Additionally, there are three natriuretic peptide receptors: Natriuretic Peptide Receptor-A (NPR-A), Natriuretic Peptide ... Recent advances in the biology of natriuretic peptides (NPs) have led to the developing of "designer" NPs. These peptides have ... While inhibiting enzymatic degradation of peptides can boost endogenous peptides, it may not be enough to achieve optimal ...
... which is commonly referred to as the signal peptide, signal sequence or leader peptide. Signal peptides form alpha-helical ... A target peptide is a short (3-70 amino acids long) peptide chain that directs the transport of a protein to a specific region ... Target+Peptide at the U.S. National Library of Medicine Medical Subject Headings (MeSH) SPdb (Signal Peptide DataBase) ... Like most signal peptides, mitochondrial targeting signals and plastid specific transit peptides are cleaved once targeting is ...
Chemerin peptides are short peptides (on the order of 9 amino acids) that are produced from the carboxyl terminus of the ... Cash, J; Greaves DR (May 2010). "Chemerin peptides promote phagocytosis in a ChemR23 and Syk dependent manner". J. Immunol. 184 ... A particular synthetic chemerin-derived peptide, termed C15, was developed at Oxford University. It showed anti-inflammatory ... "Synthetic chemerin-derived peptides suppress inflammation through ChemR23". J. Exp. Med. 205 (4): 767-75. doi:10.1084/jem. ...
... (PYY) also known as peptide tyrosine tyrosine is a peptide that in humans is encoded by the PYY gene. Peptide YY is ... Peptide YY is related to the pancreatic peptide family by having 18 of its 36 amino acids located in the same positions as ... Sandström O, El-Salhy M (February 2002). "Ontogeny and the effect of aging on pancreatic polypeptide and peptide YY". Peptides ... Imamura M (February 2002). "Effects of surgical manipulation of the intestine on peptide YY and its physiology". Peptides. 23 ( ...
... is a form of computing which uses peptides, instead of traditional electronic components. The basis of this ... For instance, while DNA is made of four building blocks, peptides are made of twenty building blocks. The peptide-antibody ... Similar to DNA computing, the parallel interactions of peptide sequences and antibodies have been used by this model to solve a ... ISBN 978-3-540-43775-8. Hubert Hug & Rainer Schuler (2001). "Strategies for the development of a peptide computer". ...