Extended-spectrum penicillin: The extended-spectrum penicillins are a group of antibiotics that have the widest antibacterial spectrum of all penicillins.Comprehensive Pharmacy Review, Leon Shargel, 6th edition, p917 Some sources identify them with antipseudomonal penicillins,Elsevier's Integrated Review Pharmacology, By Mark Kester, Kelly Dowhower Karpa, Kent E.BenzylpenicillinPropicillinProcaine benzylpenicillinCatalytic triad: A catalytic triad refers to the three amino acid residues that function together at the centre of the active site of some hydrolase and transferase enzymes (e.g. proteases, amidases, esterases, acylases, lipases and β-lactamases). An Acid-Base-Nucleophile triad is a common motif for generating a nucleophilic residue for covalent catalysis. The residues form a charge-relay network to polarise and activate the nucleophile, which attacks the substrate, forming a covalent intermediate which is then hydrolysed to regenerate free enzyme. The nucleophile is most commonly a serine or cysteine amino acid, but occasionally threonine. Because enzymes fold into complex three-dimensional structures, the residues of a catalytic triad can be far from each other along the amino-acid sequence (primary structure), however, they are brought close together in the final fold.Benzathine benzylpenicillinBacitracinQuellung reaction: The Quellung reaction is a biochemical reaction in which antibodies bind to the bacterial capsule of Streptococcus pneumoniae, Klebsiella pneumoniae, Neisseria meningitidis, Haemophilus influenzae, Page 340 Escherichia coli, and Salmonella. The antibody reaction allows these species to be visualized under a microscope.AmpicillinOST4: In molecular biology, OST4 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4) is a subunit of the oligosaccharyltransferase complex.Discovery and development of cephalosporins: Cephalosporins are a broad class of bactericidal antibiotics that include the β-lactam ring and share a structural similarity and mechanism of action with other β-lactam antibiotics (e.g.Cutaneous group B streptococcal infection: Cutaneous group B streptococcal infection may result in orbital cellulitis or facial erysipelas in neonates.Neisseria gonorrhoeae: Neisseria gonorrhoeae, also known as gonococci (plural), or gonococcus (singular), is a species of Gram-negative coffee bean-shaped diplococci bacteria responsible for the sexually transmitted infection gonorrhea.CloxacillinDrug allergyGonorrhea: Clap}}List of sorghum diseases: This article is a list of diseases of sorghum (Sorghum bicolor).Erythromycin 3''-O-methyltransferase: Erythromycin 3-O-methyltransferase (, EryG) is an enzyme with system name S-adenosyl-L-methionine:erythromycin C 3-O-methyltransferase. This enzyme catalyses the following chemical reactionCeftriaxoneStreptococcus dysgalactiae: Streptococcus dysgalactiae is a species of Streptococcus.CefotaximeStreptococcal pharyngitisBeta-lactamaseResistome: The resistome is a proposed expression by Gerard D. Wright for the collection of all the antibiotic resistance genes and their precursors in both pathogenic and non-pathogenic bacteria.CarbenicillinPenicillium funiculosum: Penicillium funiculosum is a plant pathogen infecting pineapples.GentamicinLactamFerric uptake regulator family: In molecular biology, the ferric uptake regulator (FUR) family of proteins includes metal ion uptake regulator proteins. These are responsible for controlling the intracellular concentration of iron in many bacteria.TonsillitisInfective endocarditisPeptidoglycan binding domainStaphylococcus cohnii: Staphylococcus cohnii is a Gram positive, coagulase-negative member of the bacterial genus Staphylococcus consisting of clustered cocci. The species commonly lives on human skin; clinical isolates have shown high levels of antibiotic resistance.ClindamycinStreptomycinProbenecid and colchicine: Probenecid with colchicine is a combination medication used to treat gout. Brand names include ColBenemid, Col-Probenecid, and Proben-C.AmoxicillinHistory of syphilis: The history of syphilis has been well studied, but the exact origin of syphilis is unknown. There are two primary hypotheses: one proposes that syphilis was carried to Europe from the Americas by the crew of Christopher Columbus, the other proposes that syphilis previously existed in Europe but went unrecognized.Eagle's minimal essential medium: Eagle's minimal essential medium (EMEM) is a cell culture medium developed by Harry Eagle that can be used to maintain cells in tissue culture.Chloramphenicol acetyltransferaseCefuroximeMeticillinTrans-activating crRNA: In molecular biology, trans-activating crRNA (tracrRNA) is a small trans-encoded RNA. It was first discovered in the human pathogen Streptococcus pyogenes.Exogenous bacteria: Exogenous bacteria are microorganisms introduced to closed biological systems from the external world. They exist in aquatic and terrestrial environments, as well as the atmosphere.List of strains of Escherichia coli: Escherichia coli is a well studied bacterium that was first identified by Theodor Escherich, after whom it was later named.Neisseria meningitidis: Neisseria meningitidis, often referred to as meningococcus, is a gram negative bacterium that can cause meningitis and other forms of meningococcal disease such as meningococcemia, a life-threatening sepsis. The bacterium is referred to as a coccus because it is round, and more specifically, diplococcus because of its tendency to form pairs.SaPI: SaPIs (Staphylococcus aureus or superantigen pathogenicity islands) are a family of mobile genetic elements resident in the genome of some strains of Staphylococcus aureus. Much like bacteriophages, SaPIs can be transferred to uninfected cells and integrate into the host chromosome.Macrolide: The macrolides are a group of drugs (typically antibiotics) whose activity stems from the presence of a macrolide ring, a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached. The lactone rings are usually 14-, 15-, or 16-membered.Phenyl acetateCefiximeTicarcillin/clavulanic acid: Ticarcillin/clavulanic acid, or co-ticarclav, is a combination antibiotic consisting of ticarcillin, a β-lactam antibiotic, and clavulanic acid, a β-lactamase inhibitor. This combination results in an antibiotic with an increased spectrum of action and restored efficacy against ticarcillin-resistant bacteria that produce certain β-lactamases.Streptococcus agalactiae: Streptococcus agalactiae (also known as Group B streptococcus or GBS) is a gram-positive coccus with a tendency to form chains (streptococcus), beta-hemolytic, catalase-negative, and facultative anaerobe. Streptococcus agalactiae is the species designation for streptococci belonging to the group B of the Rebecca Lancefield classification.Carboxypeptidase A inhibitor: In molecular biology, the carboxypeptidase A inhibitor family is a family of proteins which is represented by the well-characterised metallocarboxypeptidase A inhibitor (MCPI) from potatoes, which belongs to the MEROPS inhibitor family I37, clan IE. It inhibits metallopeptidases belonging to MEROPS peptidase family M14, carboxypeptidase A.NEK8: Serine/threonine-protein kinase Nek8, also known as never in mitosis A-related kinase 8, is an enzyme that in humans is encoded by the NEK8 gene.AllysineVancomycinCHAP domain: In molecular biology, the CHAP domain is a region between 110 and 140 amino acids that is found in proteins from bacteria, bacteriophages, archaea and eukaryotes of the Trypanosomidae family. The domain is named after the acronym cysteine, histidine-dependent amidohydrolases/peptidases.ATC code S01: ==S01A Anti-infectives==Enterococcus faecalis: Enterococcus faecalis – formerly classified as part of the group D Streptococcus system – is a Gram-positive, commensal bacterium inhabiting the gastrointestinal tracts of humans and other mammals. Like other species in the genus Enterococcus, E.Sarcina (genus): Sarcina is a genus of Gram-positive cocci bacteria in the family Clostridiaceae. A synthesizer of microbial cellulose, they have a cuboidal cell arrangement.CefalexinSortasePGLO: The pGLO plasmid is an engineered plasmid used in biotechnology as a vector for creating genetically modified organisms. The plasmid contains several reporter genes, most notably for the green fluorescent protein (GFP) and the ampicillin resistance gene.CodinaeopsinGroup A streptococcal infectionChronic recurrent erysipelas: Chronic recurrent erysipelas is a cutaneous condition with several predisposing factors including alcoholism, diabetes, and tinea pedis (athlete's foot).Cell envelope antibiotic: A cell envelope antibiotic is an antibacterial that acts primarily at the level of the cell envelope.Cell envelope: The cell envelope comprises the inner cell membrane and the cell wall of a bacterium, if present, plus a bacterial outer membrane, if one is present (i.e.
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