... allowing detection of pancreatic pathology, especially cancer not yet visible on medical imaging.. Pancreatic juice is secreted ... "Optimization of Pancreatic Juice Collection: A First Step Toward Biomarker Discovery and Early Detection of Pancreatic Cancer ... Pancreatic juice is alkaline in nature due to the high concentration of bicarbonate ions. Bicarbonate is useful in neutralizing ... Pancreatic juice is a liquid secreted by the pancreas, which contains a number of digestive enzymes, including trypsinogen, ...
"The source of pancreatic juice bicarbonate." Journal of Biological Chemistry 140 (1941): 119-129. Tucker, Helen F.; Ball, Eric ... "The Source of Pancreatic Juice Bicarbonate" (1941, with Eric G. Ball, A. K. Solomon, and Birgit Vennesland) "The Activity of ... "The Activity of Carbonic Anydrase in Relation to the Secretion and Composition of Pancreatic Juice". The Journal of Biological ... Carbonic Anydrase in Relation to the Secretion and Composition of Pancreatic Juice" (1941, with Eric G. Ball) Tucker died in ...
Hyun J, Kothari H, Herm E, Mortenson J, Treadwell CR, Vahouny GV (1969). "Purification and properties of pancreatic juice ...
He studied bile and pancreatic juices. Some of this work was done with Friedrich Bidder. He studied chemical changes in blood ... He discovered hydrochloric acid in gastric juice and its chemical interaction with pepsin. ...
Fatal effect of the total loss of pancreatic juice. Proc. Soc. Exp. Biol. Med., 28:110-11. 1931 With M. L. Montgomery, J. C. ... On the corrosive properties of bile and pancreatic juice on living tissue in dogs. Arch. Surg., 108:680-84. 1976 With J. B. ... Gastric juice in duodenal and gastric ulcers. J. Am. Med. Assoc, 68:330-33. With J. J. Moorhead and F. W. Burcky. An ... Arteriosclerosis in pancreatic diabetes. Surgery, 8:353-61. 1942 With C. Vermeulen, D. E. Clark, O. C. Julian, and J. G. Allen ...
"Identification of pancreatic juice proteins as biomarkers of pancreatic cancer". Oncology Reports. 23 (6): 1683-92. doi:10.3892 ... "Protein profiling of human pancreatic islets by two-dimensional gel electrophoresis and mass spectrometry". Journal of Proteome ...
Gabriel Gustav Valentin notes the digestive activity of pancreatic juice. George Robert Gray begins publication in London of ...
Its function is to complete the process begun by pancreatic juice; the enzyme trypsin exists in pancreatic juice in the ... Intestinal juice (also called succus entericus) refers to the clear to pale yellow watery secretions from the glands lining the ... Colipase is necessary, along with bile salts, to enable lipase function.[citation needed] Intestinal juice also contains ... inactive form trypsinogen, it is activated by the intestinal enterokinase in intestinal juice. Trypsin can then activate other ...
It is produced by the pancreas and found in pancreatic juice, along with amylase, lipase, and chymotrypsinogen. It is cleaved ... Three isoforms of trypsinogens may be found in human pancreatic juice. These are the cationic, anionic, and meso trypsinogen, ... Trypsinogen is released by the pancreas into the second part of the duodenum, via the pancreatic duct, along with other ... Premature trypsin activation can be destructive and may trigger a series of events that lead to pancreatic self-digestion. In ...
This conserves pancreatic juices that would otherwise be lost. This surgery is performed by a pancreatic surgeon to avoid a ... Pancreatic pseudocysts are chronic collections of pancreatic fluid encased by a wall of nonepithelialized granulation tissue ... Cystogastrostomy can lead to pancreatic abscess and pancreatic duct leak. Stents can become blocked, leading to infection of ... Cystogastrostomy is a surgery to create an opening between a pancreatic pseudocyst and the stomach when the cyst is in a ...
1982). "Studies on prophospholipase A2 and its enzyme from human pancreatic juice. Catalytic properties and sequence of the N- ... Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is ... Seilhamer JJ, Randall TL, Yamanaka M, Johnson LK (1987). "Pancreatic phospholipase A2: isolation of the human gene and cDNAs ... Sternby B, Akerström B (1984). "Immunoreactive pancreatic colipase, lipase and phospholipase A2 in human plasma and urine from ...
One possible cause of impaired drainage of pancreatic juice is blockage of the sphincter of Oddi. A common cause of blockage is ... The sphincter regulates the secretion of pancreatic juice and bile into the duodenum. It also prevents reflux of duodenal ... controls the flow of bile and pancreatic juice out of the gallbladder and pancreas respectively through the ampulla of Vater ... Pancreatitis can result from a failure of pancreatic secretions to drain properly. ...
This supplies it with pancreatic juice from the exocrine pancreas, which aids in digestion. The pancreatic duct joins the ... The pancreatic duct, or duct of Wirsung (also, the major pancreatic duct due to the existence of an accessory pancreatic duct ... Pancreatic ductal carcinoma is a common form of pancreatic cancer. The pancreatic duct is also called the duct of Wirsung. This ... where it blocks the flow of both bile and pancreatic juice into the duodenum. Bile backing up into the pancreatic duct may ...
1988). "Characterization of two glycoproteins of human pancreatic juice: P35, a truncated protease E and P19, precursor of ... "Identification of a procarboxypeptidase A-truncated protease E binary complex in human pancreatic juice". FEBS Lett. 250 (2): ... Tani T, Ohsumi J, Mita K, Takiguchi Y (Feb 1988). "Identification of a novel class of elastase isozyme, human pancreatic ... Shen WF, Fletcher TS, Largman C (1987). "Primary structure of human pancreatic protease E determined by sequence analysis of ...
"Stimulatory effect of an endogenous peptide in rat pancreatic juice on pancreatic enzyme secretion in the presence of atropine ... It was purified from rat bile-pancreatic juice and the peptide sequence was elucidated. Monitor peptide is composed of 61 amino ... Monitor peptide, also known as pancreatic secretory trypsin inhibitor I (PSTI-I) or pancreatic secretory trypsin inhibitor 61 ( ... Rat Pancreatic Secretory Trypsin Inhibitor/Monitor Peptide Provides Protection against Premature Activation of Pancreatic Juice ...
... mix their production with acinar cells to make up the pancreatic juice. Ductal cells comprise about 10% of the ... Pancreatic adenocarcinoma cells resemble pancreatic ductal cells. Both cell groups show tubule formation, cuboidal shape, and ... Interlobular ducts originate from the main pancreatic duct and connect the various pancreatic lobes. In these lobes, the ... In fact, chronic pancreatitis often causes pancreatic adenocarcinoma. Pancreatic Ductal Adenocarcinoma (PDAC) is one of the ...
Patients who have pancreatic ductal adenocarcinoma show an overexpression of A1BG in pancreatic juice. A1BG is located on the ... DJ-1 and A1BG as overexpressed proteins in pancreatic juice from pancreatic ductal adenocarcinoma patients". BMC Cancer. 8: 241 ...
"Measurement of tryptic activity in intestinal juice as a diagnostic test of pancreatic disease." Gut 8, no. 4 (1967): 408-414 ...
When bile becomes blocked, pancreatic juices cannot be transported to the intestines. Bile leakage causes inflammation in ... Destruction of the billary tree means that there is a blockage in the pancreatic or bile duct. Bile ducts are vessels that ...
... is present in the pancreatic juice of several species". Biochim Biophys Acta. 1387 (1-2): 331-41. doi:10.1016/S0167-4838(98) ... Crenon I, Foglizzo E, Kerfelec B, Verine A, Pignol D, Hermoso J, Bonicel J, Chapus C (1998). "Pancreatic lipase-related protein ... De Caro J, Carriere F, Barboni P, Giller T, Verger R, De Caro A (1998). "Pancreatic lipase-related protein 1 (PLRP1) ... Withers-Martinez C; Carriere F; Verger R; Bourgeois D; C Cambillau (1996). "A pancreatic lipase with a phospholipase A1 ...
Gabriel Valentin showed pancreatic juices break down food in digestion. 1846 Justus Von Leibig discovered pancreatic juice ... "Pancreatic Diseases". Nih.gov. Retrieved 24 December 2016. "NLM Classification Home Page". Nih.gov. Retrieved 24 December 2016 ... C06.552 Liver Diseases C06.130 Biliary Tract Diseases C06.689 Pancreatic diseases 3. National Library of Medicine Catalogue WI ...
He co-authored his first scientific paper in 1906, titled Amylolytic inactivity of dialyzed pancreatic juice. His other initial ...
In the pancreas, FGF21 favors the formation of pancreatic juice through a β-klotho dependent mechanism. Whether an ... while conditions that promote energy storage induce WAT and pancreatic FGF21. The FGF superfamily comprehends nearly two dozen ...
"Retortamonas intestinalis in the pancreatic juice of a patient with small nodular lesions of the main pancreatic duct". ...
The pancreas produces and releases important digestive enzymes in the pancreatic juice that it delivers to the duodenum. The ... Aqueous pancreatic secretions from pancreatic duct cells contain bicarbonate ions which are alkaline and help with the bile to ... the duodenum via the pancreatic duct which it joins near to the bile duct's connection where both the bile and pancreatic juice ... This breaks down fats to some degree though is not as efficient as the pancreatic lipase. The pylorus, the lowest section of ...
Freeman TC, Davies R, Calam J (Dec 1990). "Interactions of pancreatic secretory trypsin inhibitor in small intestinal juice: ... Pancreatic secretory trypsin inhibitor (PSTI) also known as serine protease inhibitor Kazal-type 1 (SPINK1) or tumor-associated ... Tomita N, Horii A, Yamamoto T, Ogawa M, Mori T, Matsubara K (Dec 1987). "Expression of pancreatic secretory trypsin inhibitor ... Chen JM, Mercier B, Audrezet MP, Ferec C (Jan 2000). "Mutational analysis of the human pancreatic secretory trypsin inhibitor ( ...
Freeman TC, Davies R, Calam J (1990). "Interactions of pancreatic secretory trypsin inhibitor in small intestinal juice: its ...
In the duodenum pancreatic proteases (a component of pancreatic juice) cleave haptocorrin, releasing vitamin B12 in its free ...
In the first, he took out almost all of the pancreas, cutting off the supply of pancreatic juice entirely. He then left a small ... Claude Bernard demonstrated the function of pancreatic juice in digestion between 1849 and 1856, clarifying an important link ... Banting wrote a note on October 31 of that year describing his thinking: "Ligate pancreatic ducts of dog. Keep dogs alive till ... Now there was nothing new in the idea of producing degeneration or atrophy of the acinar tissues by ligating the pancreatic ...
"Preparation and characterization of reference materials for human pancreatic lipase: BCR 693 (from human pancreatic juice) and ... Pancreatic lipase, also known as pancreatic triacylglycerol lipase or steapsin, is an enzyme secreted from the pancreas. As the ... Unlike some pancreatic enzymes that are activated by proteolytic cleavage (e.g., trypsinogen), pancreatic lipase is secreted in ... "Entrez Gene: pancreatic lipase". Koop H (September 1984). "Serum levels of pancreatic enzymes and their clinical significance ...