... at herkules.oulu.fi Ornithine+decarboxylase at the U.S. National Library of Medicine Medical Subject ... The enzyme ornithine decarboxylase (EC 4.1.1.17, ODC) catalyzes the decarboxylation of ornithine (a product of the urea cycle) ... Lysine 69 on ornithine decarboxylase (ODC) binds the cofactor pyridoxal phosphate to form a Schiff base. Ornithine displaces ... The ornithine decarboxylation reaction catalyzed by ornithine decarboxylase is the first and committed step in the synthesis of ...

... (ODC-AZ) is an ornithine decarboxylase inhibitor. It binds to, and destabilises, ornithine ... SGD entry for OAZ1 gene ornithine+decarboxylase+antizyme at the U.S. National Library of Medicine Medical Subject Headings ( ... Heller JS, Canellakis ES (1981). "Cellular control of ornithine decarboxylase activity by its antizyme". J. Cell. Physiol. 107 ... Human genes encoding Ornithine decarboxylase antizymes are OAZ1, OAZ2, and OAZ3. Matsufuji S, Matsufuji T, Miyazaki Y, Murakami ...

Ornithine Decarboxylase tests yield negative results. Treatment for shigellosis, independent of the subspecies, requires an ...

Ornithine decarboxylase antizyme is an enzyme that in humans is encoded by the OAZ1 gene. Ornithine decarboxylase catalyzes the ... The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ... "Entrez Gene: OAZ1 ornithine decarboxylase antizyme 1". Coffino P (2000). "Polyamines in spermiogenesis: not now, darling". Proc ... 2007). "Ornithine decarboxylase antizyme upregulates DNA-dependent protein kinase and enhances the nonhomologous end-joining ...

Ornithine decarboxylase antizyme 2 is an enzyme that in humans is encoded by the OAZ2 gene. Ornithine decarboxylase catalyzes ... The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ... "Entrez Gene: OAZ2 ornithine decarboxylase antizyme 2". Coffino P (2000). "Polyamines in spermiogenesis: not now, darling". Proc ... Zhou J, Atkins JF, Gesteland RF (Jul 1999). "Structure of human ornithine decarboxylase antizyme 2 gene". Gene. 232 (2): 165-71 ...

Ornithine decarboxylase Internal ribosome entry site Pyronnet, S; Pradayrol, L; Sonenberg, N (April 2000). "A cell cycle- ... It has been suggested that this IRES allows cap-independent translation of ornithine decarboxylase at the G2/M phase of the ... UTR of ornithine decarboxylase mRNA on its translation". Biochemical and Biophysical Research Communications. 364 (1): 124-130 ... "Ras transformation of RIE-1 cells activates cap-independent translation of ornithine decarboxylase: regulation by the Raf/MEK/ ...

Her work in this realm included investigations into enzymes including ornithine decarboxylase and histidine decarboxylase. She ... Guirard, B. M.; Snell, E. E. (1980-06-25). "Purification and properties of ornithine decarboxylase from Lactobacillus sp. 30a ... Guirard, B M; Tanase, S; Snell, E E (1984-01-01). "Pyridoxal-P dependent bacterial histidine decarboxylase". Progress in ... phosphate-dependent histidine decarboxylases from Klebsiella planticola and Enterobacter aerogenes". Journal of Bacteriology. ...

"An endosymbiont positively modulates ornithine decarboxylase in host trypanosomatids". Biochem Biophys Res Commun. 343 (2): 443 ... and that it helps the host in synthesising the amino acid arginine from ornithine. As more structural and molecular details ... "Endosymbiont as supplier of ornithine carbamoyltransferase in a trypanosomatid". Nature. 270 (5632): 52-53. Bibcode:1977Natur. ...

Examples of ATE1 targets which have been identified include ornithine decarboxylase., thyroglobulin, insulin, and neurotensin. ... "Post-translational arginylation of ornithine decarboxylase from rat hepatocytes". The Biochemical Journal. 267 (2): 343-348. ...

Ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine ... Ornithine decarboxylase (ODC) catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting ... 2000). "Degradation of ornithine decarboxylase by the 26S proteasome". Biochem. Biophys. Res. Commun. 267 (1): 1-6. doi:10.1006 ... "Cloning and sequencing of a human cDNA encoding ornithine decarboxylase antizyme inhibitor". Biochim Biophys Acta. 1353 (3): ...

Ornithine decarboxylase (ODC), is a labile protein that is the first rate-limiting enzyme in polyamine biosynthesis. Its ... Asher G, Bercovich Z, Tsvetkov P, Shaul Y, Kahana C (Mar 2005). "20S proteasomal degradation of ornithine decarboxylase is ...

November 2004). "Loss of methylthioadenosine phosphorylase and elevated ornithine decarboxylase is common in pancreatic cancer ... "Methylthioadenosine phosphorylase regulates ornithine decarboxylase by production of downstream metabolites". The Journal of ...

The most well-known example of a ubiquitin-independent proteasome substrate is the enzyme ornithine decarboxylase. Ubiquitin- ... Zhang M, Pickart CM, Coffino P (April 2003). "Determinants of proteasome recognition of ornithine decarboxylase, a ubiquitin- ...

Mello, F. G. De; Bachrach, U.; Nirenberg, M. (1976). "Ornithine and Glutamic Acid Decarboxylase Activities in the Developing ... giving space to Glutamate Decarboxylase. Years later, de Mello also discovered that GABA regulates Glutamate Decarboxylase ... de Mello, Fernando G. (1984-05-01). "GABA-mediated control of glutamate decarboxylase (GAD) in cell aggregate culture of chick ... Glutamate decarboxylase. This led him to hypothesize the existence of an alternative synthesis pathway for GABA. Indeed, ...

Grishin NV, Phillips MA, Goldsmith EJ (July 1995). "Modeling of the spatial structure of ornithine decarboxylases". Protein Sci ...

Ornithine decarboxylase can catalyse the decarboxylation of DFMO instead of ornithine (see the "DFMO inhibitor mechanism" ... "Mechanism of the irreversible inactivation of mouse ornithine decarboxylase by alpha-difluoromethylornithine. Characterization ... which is an analogue of the amino acid ornithine, and is used to treat African trypanosomiasis (sleeping sickness). ...

"Transcription factor ZBP-89 regulates the activity of the ornithine decarboxylase promoter". The Journal of Biological ...

In molecular biology, group IV pyridoxal-dependent decarboxylases are a family of enzymes comprising ornithine decarboxylase EC ... Group IV comprises eukaryotic ornithine and lysine decarboxylase and the prokaryotic biosynthetic type of arginine ... It is also known as the Orn/Lys/Arg decarboxylase class-II family. Pyridoxal-5'-phosphate-dependent amino acid decarboxylases ... Group I pyridoxal-dependent decarboxylases Group II pyridoxal-dependent decarboxylases Group III pyridoxal-dependent ...

... irreversibly binding to ornithine decarboxylase (ODC) and preventing the natural substrate ornithine from accessing the active ... It has been noted that ornithine decarboxylase (ODC) exhibits high activity in tumor cells, promoting cell growth and division ... Grishin NV, Osterman AL, Brooks HB, Phillips MA, Goldsmith EJ (November 1999). "X-ray structure of ornithine decarboxylase from ... There are two distinct active sites formed by the homodimerization of ornithine decarboxylase. The size of the opening to the ...

"Human ornithine decarboxylase paralogue (ODCp) is an antizyme inhibitor but not an arginine decarboxylase" (PDF). The ... "Human ornithine decarboxylase paralogue (ODCp) is an antizyme inhibitor but not an arginine decarboxylase" (PDF). The ... "Mouse ornithine decarboxylase-like gene encodes an antizyme inhibitor devoid of ornithine and arginine decarboxylating activity ... "Mouse ornithine decarboxylase-like gene encodes an antizyme inhibitor devoid of ornithine and arginine decarboxylating activity ...

March 1998). "Expression of ornithine decarboxylase mRNA and c-myc mRNA in breast tumours". International Journal of Oncology. ...

This enzyme is not found in humans, but the ortholog is ornithine decarboxylase. DAPDC is a PLP-dependent enzyme belonging to ... There is no process for producing lysine in humans, but ornithine decarboxylase shares many similarities with DAPDC. Both ... Fogle EJ, Toney MD (September 2011). "Analysis of catalytic determinants of diaminopimelate and ornithine decarboxylases using ... The enzyme diaminopimelate decarboxylase (EC 4.1.1.20) catalyzes the cleavage of carbon-carbon bonds in meso 2,6 ...

The increase in prolactin induces expression of the gene Odc (ornithine decarboxylase). The Odc gene produces the ODC protein, ...

... a new ornithine decarboxylase-positive species that may cause diarrhea". Journal of Clinical Microbiology. 25 (5): 900-906. doi ...

N V Grishin; M A Phillips; E J Goldsmith (July 1995). "Modeling of the spatial structure of eukaryotic ornithine decarboxylases ...

Grishin NV, Phillips MA, Goldsmith EJ (July 1995). "Modeling of the spatial structure of eukaryotic ornithine decarboxylases". ...

... metabolism is regulated by the activity of the enzyme ornithine decarboxylase (ODC). Polyamines are found in high ... Polyamines in cell cycle proliferation and cell death Ornithine Decarboxylase: Expression and regulation in rat brain and in ...

Biosynthesis begins with decarboxylation of ornithine by ornithine decarboxylase (ODC) to produce putrescine. Putrescine is ... Lamberts BL, Dewey LJ, Byerrum RU (May 1959). "Ornithine as a precursor for the pyrrolidine ring of nicotine". Biochimica et ...

Loetscher, P.; Pratt, G.; Rechsteiner, M. (1991-06-15). "The C terminus of mouse ornithine decarboxylase confers rapid ... first characterized in yeast to the PEST sequence of mouse ornithine decarboxylase. Degrons have been identified in prokaryotes ...

Eflornithine irreversible inhibits ornithine decarboxylase which is an important enzyme involved in hair growth. Elfornithine ...