Octamer transcription factors are a family of transcription factors which binds to the "ATTTGCAT" DNA sequence. Their DNA- ... Octamer+transcription+factors at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Articles with short ... Zhao, FQ (1 June 2013). "Octamer-binding transcription factors: genomics and functions". Frontiers in Bioscience (Landmark ... "Characterization of chicken octamer-binding proteins demonstrates that POU domain-containing homeobox transcription factors ...

June 1998). "Recruitment of octamer transcription factors to DNA by glucocorticoid receptor". Molecular and Cellular Biology. ... "Selective binding of steroid hormone receptors to octamer transcription factors determines transcriptional synergism at the ... The biological response depends on the cell type.[citation needed] In the absence of activated GR, other transcription factors ... However activated GR can complex with these other transcription factors and prevent them from binding their target genes and ...

Sp1 transcription factor, and TATA binding protein. Octamer transcription factor GRCh38: Ensembl release 89: ENSG00000143190 - ... assembly factor, MAT1, targets and enhances CAK activity on the POU domains of octamer transcription factors". J. Biol. Chem. ... "Recruitment of octamer transcription factors to DNA by glucocorticoid receptor". Mol. Cell. Biol. 18 (6): 3416-30. doi:10.1128/ ... "Recruitment of Octamer Transcription Factors to DNA by Glucocorticoid Receptor". Mol. Cell. Biol. 18 (6): 3416-30. doi:10.1128/ ...

Octamer transcription factor GRCh38: Ensembl release 89: ENSG00000185668 - Ensembl, May 2017 "Human PubMed Reference:". ... "High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors". The EMBO Journal. ... POU domain, class 3, transcription factor 1 (also known as Oct-6) is a protein that in humans is encoded by the POU3F1 gene. ... "Entrez Gene: POU3F1 POU domain, class 3, transcription factor 1". Monuki ES, Kuhn R, Weinmaster G, Trapp BD, Lemke G (Sep 1990 ...

"High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors". The EMBO Journal. ... "Phage display screening reveals an association between germline-specific transcription factor Oct-4 and multiple cellular ... Transcription factors, All stub articles, Human chromosome 4 gene stubs). ... 14 (6): 1198-208. doi:10.1002/j.1460-2075.1995.tb07103.x. PMC 398197. PMID 7720710. Shykind BM, Kim J, Sharp PA (Jun 1995). " ...

"Assignment of the human gene for Oct-binding factor-1 (OBF1), a B-cell-specific coactivator of octamer-binding transcription ... "A B-cell coactivator of octamer-binding transcription factors". Nature. 373 (6512): 360-2. Bibcode:1995Natur.373..360G. doi: ... BOB1 is a transcriptional coactivator (i.e. a protein that controls the activity of transcription factors) which is expressed ... POU domain POU domain class 2 transcription factors: POU2F1, POU2F2, POU2F3 GRCh38: Ensembl release 89: ENSG00000110777 - ...

B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors". ... Roeder RG, Engelke DR, Luse DS, Segall J, Shastry BS, Weil PA (1979). "Factors involved in the transcription of purified genes ... Segall J, Matsui T, Roeder RG (Dec 1980). "Multiple factors are required for the accurate transcription of purified genes by ... Engelke DR, Ng SY, Shastry BS, Roeder RG (Mar 1980). "Specific interaction of a purified transcription factor with an internal ...

"Selective binding of steroid hormone receptors to octamer transcription factors determines transcriptional synergism at the ... The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcription factors. ... "Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR gamma and RXR ... "Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR gamma and RXR ...

Octamer-binding transcription factor 4, OCT-4, is a transcription factor protein that is encoded by the POU5F1 gene and is part ... Oct-4 (octamer-binding transcription factor 4), also known as POU5F1 (POU domain, class 5, transcription factor 1), is a ... assembly factor, MAT1, targets and enhances CAK activity on the POU domains of octamer transcription factors". The Journal of ... Oct-4 transcription factor is initially active as a maternal factor in the oocyte and remains active in embryos throughout the ...

The GCM motif has been shown to be a DNA binding domain that recognises preferentially the nonpalindromic octamer 5'-ATGCGGGT-3 ... In molecular biology, the GCM transcription factors are a family of proteins which contain a GCM motif. The GCM motif is a ... Schreiber J, Sock E, Wegner M (April 1997). "The regulator of early gliogenesis glial cells missing is a transcription factor ... In GCM transcription factors the N-terminal moiety contains a DNA-binding domain of 150 amino acids. Sequence conservation is ...

"Silencing mediator for retinoid and thyroid hormone receptors interacts with octamer transcription factor-1 and acts as a ... NCOR2/SMRT serves as a repressive coregulatory factor (corepressor) for multiple transcription factor pathways. In this regard ... facilitating the recruitment of histone deacetylases to the DNA promoters bound by its interacting transcription factors. It is ... "Arsenic trioxide is a potent inhibitor of the interaction of SMRT corepressor with Its transcription factor partners, including ...

... assembly factor, MAT1, targets and enhances CAK activity on the POU domains of octamer transcription factors". J. Biol. Chem. ... targets and enhances CAK activity on the POU domains of octamer transcription factors". J. Biol. Chem. 272 (47): 29852-8. doi: ... the fifth subunit of the core of the transcription/DNA repair factor TFIIH". EMBO J. 16 (5): 1093-102. doi:10.1093/emboj/16.5. ... "Isolation and characterization of two human transcription factor IIH (TFIIH)-related complexes: ERCC2/CAK and TFIIH". Proc. ...

Octamer transcription factor GRCh38: Ensembl release 89: ENSG00000184486 - Ensembl, May 2017 "Human PubMed Reference:". ... a nervous-system specific POU domain transcription factor binding to the octamer DNA motif". Nucleic Acids Research. 21 (2): ... which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and ... POU domain, class 3, transcription factor 2 is a protein that in humans is encoded by the POU3F2 gene. N-Oct-3 is a protein ...

In Drosophila, NURF interacts with the transcription factor GAGA to remodel chromatin at the hsp70 promoter, and null mutations ... NURF catalyzes nucleosome sliding in either direction on DNA without any apparent modifications to the histone octamer itself. ... NURF interacts with chromatin by binding to modified histones or interacting with various transcription factors. ... Nucleosome Remodeling Factor (NURF) is an ATP-dependent chromatin remodeling complex first discovered in Drosophila ...

Tantin D.; Schild-Poulter C.; Wang V.; Hache R.J.; Sharp P.A. (December 1, 2005). "The Octamer Binding Transcription Factor Oct ... Lee K.B.; Sharp P.A. (December 7, 2004). "Transcription-dependent Polyubiquitination of RNA Polymerase II Requires Lysine 63 of ... and has discovered a class of miRNAs that are produced from sequences adjacent to transcription start sites. His laboratory ... 30 (6): 279-81. doi:10.1016/j.tibs.2005.04.002. PMID 15950867. Johnson D.M.; Yamaji S.; Tennant J.; Srai S.K.; Sharp P.A. ( ...

Ben-Shushan E, Thompson JR, Gudas LJ, Bergman Y (April 1998). "Rex-1, a gene encoding a transcription factor expressed in the ... Rex1 participates in a network of transcription factors that all work to regulate each other via varying expression levels. The ... Rex1 was also found to inhibit NOTCH and STAT3, two transcription factors which lead to differentiation. Therefore, Rex1 ... April 2005). "Human bone marrow mesenchymal stem cells can express insulin and key transcription factors of the endocrine ...

Transcription factors Transcription factors with highest matrix scores that bind to sequences within the promoter (ID GXP_ ... CCCTC-binding factor) HDBP (Huntington's disease gene regulatory region) OCT1 (octamer binding protein) E2FF (E2F-myc activator ... C2H2 zinc finger transcription factor 7) EGRF (EGR/nerve growth factor induced protein) CDEF (cell cycle dependent element - ... 1499160) are shown below: STAT (signal transducer and activator of transcription) Muscle TATA box NOLF (neuron-specific ...

Transcriptions factors have different binding sites for its development, some examples are: GATA, activator protein 1 and 2 (AP ... and AP-2), and numerous potential Octamer-1 binding sites. A Glycogenin-1 deficiency leads to Glycogen storage disease type XV ... There are also nine E-boxes that bind the basic helix-loop-helix of muscle-specific transcription factors. The GYG1 gene is ... Transcription of human glycogenin-1 is mainly initiated at 80bp and 86bp upstream the translator's codon beginning. ...

Nuclear respiratory factor 1 RXR heterodimer binding sites GATA binding factors Nuclear receptor subfamily 2 factors Octamer ... transcription factors with a GCM DNA binding domain Signal transducer and activator of transcription Heat shock factors (2 ... More than one hundred transcription factor binding sites were predicted to be found in the megf8 promoter region through ... binding protein EGR/nerve growth factor induced protein C & related factors Neuron-restrictive silencer factor MEGF8 is ...

1.65 turns around histone protein octamers. DNA within nucleosomes is inaccessible to many transcription factors. Some ... Plant transcription factor database TcoF-DB: Database of transcription co-factors and transcription factor interactions ... This is also true with transcription factors: Not only do transcription factors control the rates of transcription to regulate ... an important class of transcription factors called general transcription factors (GTFs) are necessary for transcription to ...

"The transcription factor Spi-1/PU.1 interacts with the potential splicing factor TLS". The Journal of Biological Chemistry. 273 ... Hallier M, Tavitian A, Moreau-Gachelin F (May 1996). "The transcription factor Spi-1/PU.1 binds RNA and interferes with the RNA ... Hallier M, Tavitian A, Moreau-Gachelin F (May 1996). "The transcription factor Spi-1/PU.1 binds RNA and interferes with the RNA ... protein-associated splicing factor, and SF-1, a complex that also participates in repression of transcription". Endocrinology. ...

Pituitary-specific positive transcription factor 1, Pou1f1), Oct1 (Pou2f1), and the Caenorhabditis elegans factor Unc86, and ... and endocrine systems that functions on elements distinct from known octamer motifs". Proceedings of the National Academy of ... interacts with the Brn-3a POU transcription factor and inhibits its ability to activate transcription". Cancer Biology & ... interacts with the Brn-3a POU transcription factor and inhibits its ability to activate transcription". Cancer Biology & ...

Dantonel JC, Murthy KG, Manley JL, Tora L (1997). "Transcription factor TFIID recruits factor CPSF for formation of 3' end of ... Hoffmann A, Chiang CM, Oelgeschläger T, Xie X, Burley SK, Nakatani Y, Roeder RG (1996). "A histone octamer-like structure ... Transcription initiation factor TFIID subunit 12 is a protein that in humans is encoded by the TAF12 gene. Control of ... Overview of all the structural information available in the PDB for UniProt: Q16514 (Transcription initiation factor TFIID ...

1993). "In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factor". J. Virol ... Liu YZ, Latchman DS (1997). "The octamer-binding proteins Oct-1 and Oct-2 repress the HIV long terminal repeat promoter and its ... interaction between the HIV-1 Tat transactivator and the inhibitory domain of the Oct-2 cellular transcription factor". AIDS. ... 276 (36): 33741-6. doi:10.1074/jbc.M104617200. PMID 11447227. Boehm J, He Y, Greiner A, et al. (2001). "Regulation of BOB.1/OBF ...

"In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factor". Journal of ... Liu YZ, Latchman DS (February 1997). "The octamer-binding proteins Oct-1 and Oct-2 repress the HIV long terminal repeat ... interaction between the HIV-1 Tat transactivator and the inhibitory domain of the Oct-2 cellular transcription factor". AIDS. ... "Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA ...

Depending on the context, nucleosomes can inhibit or facilitate transcription factor binding. Nucleosome positions are ... which are known as a histone octamer. Each histone octamer is composed of two copies each of the histone proteins H2A, H2B, H3 ... presumably because transcription factor binding sites became more or less accessible, respectively. In general, only one or two ... such as transcription factors. Nucleosome free region typically spans for 200 nucleotides in S. cerevisiae Well-positioned ...

These regions tend to coincide with transcription factor genes expressed at low levels. Some of these factors, such as the Hox ... The basic structural unit of chromatin is the Nucleosome: this consists of the core octamer of histones (H2A, H2B, H3 and H4) ... This makes the DNA in the chromatin accessible for transcription factors, allowing the genes to be transcribed and expressed in ... This makes the DNA in the chromatin more accessible for transcription factors, allowing the genes to be transcribed and ...

In mouse ESCs, Sall4 was found to bind the essential stem cell factor, octamer-binding transcription factor 4 (Oct4), in two ... "Stemness-related factor Sall4 interacts with transcription factors Oct-3/4 and Sox2 and occupies Oct-Sox elements in mouse ... Sal-like protein 4 (SALL4) is a transcription factor encoded by a member of the Spalt-like (SALL) gene family, SALL4. The SALL ... a stem cell transcription factor". Cell Cycle. 13 (9): 1456-1462. doi:10.4161/cc.28418. PMC 4050143. PMID 24626181. Gao C, ...

Most of the time, between cell divisions, chromatin is optimized to allow easy access of transcription factors to active genes ... where the double helix is wrapped around the histone octamer containing two copies of each histone H2A, H2B, H3 and H4. Linker ... Many aspects of transcription are controlled by chemical modification on the histone proteins, known as the histone code. ... including factors like salt concentration, pH, and temperature. Under physiological conditions (e.g., near-neutral pH and ...

... sp4 transcription factor MeSH D12.776.930.632.500.100 - octamer transcription factor-1 MeSH D12.776.930.632.500.200 - octamer ... octamer transcription factor-3 MeSH D12.776.930.632.500.600 - octamer transcription factor-6 MeSH D12.776.930.632.625.500 - ... transcription factor brn-3b MeSH D12.776.930.632.625.875 - transcription factor brn-3c MeSH D12.776.930.635.600.100 - ets- ... mafg transcription factor MeSH D12.776.930.127.656.750.750 - mafk transcription factor MeSH D12.776.930.127.656.770 - nf-e2 ...