"Activation of the human mitochondrial transcription factor A gene by nuclear respiratory factors: a potential regulatory link ... "Entrez Gene: NRF1 nuclear respiratory factor 1". Wang C, Li Z, Lu Y, Du R, Katiyar S, Yang J, Fu M, Leader JE, Quong A, ... Novikoff PM, Pestell RG (2006). "Cyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and ... "Respiratory uncoupling induces delta-aminolevulinate synthase expression through a nuclear respiratory factor-1-dependent ...

"Nuclear localization domain of thyroid transcription factor-1 in respiratory epithelial cells". The Biochemical Journal. 328 ( ... Guazzi S, Price M, De Felice M, Damante G, Mattei MG, Di Lauro R (November 1990). "Thyroid nuclear factor 1 (TTF-1) contains a ... "Entrez Gene: NKX2-1". Guazzi S, Price M, De Felice M, Damante G, Mattei MG, Di Lauro R (November 1990). "Thyroid nuclear factor ... "Gene structure and expression of human thyroid transcription factor-1 in respiratory epithelial cells". The Journal of ...

... regulation by myogenin and nuclear respiratory factor-1". Gene. 344: 143-59. doi:10.1016/j.gene.2004.09.035. PMID 15656981. ... 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. ...

Many nuclear-derived transcription factors have played a role in respiratory chain expression. These factors may have also ... Nuclear respiratory factor (NRF-1) fuses to respiratory encoding genes proteins, to the rate-limiting enzyme in biosynthesis, ... The second nuclear respiratory factor (NRF-2) is necessary for the production of cytochrome c oxidase subunit IV (COXIV) and Vb ... and mtDNA regulatory factors are all encoded by nuclear genes. Because nuclear genes constitute the genetic foundation of all ...

... is regulated by nuclear respiratory factor 1". The Journal of Biological Chemistry. 285 (44): 33602-13. doi:10.1074/jbc. ... Eloranta, JJ; Zaïr, ZM; Hiller, C; Häusler, S; Stieger, B; Kullak-Ublick, GA (November 2009). "Vitamin D3 and its nuclear ... "Technical and biochemical factors affecting cerebrospinal fluid 5-MTHF, biopterin and neopterin concentrations". Molecular ...

"Nuclear respiratory factor 2 activates transcription of human mitochondrial translation initiation factor 2 gene". ... Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation ... The process is simpler in bacteria which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved ... Eukaryotic translation initiation factor 5B is a protein that in humans is encoded by the EIF5B gene. Accurate initiation of ...

... is regulated by nuclear respiratory factor 1". The Journal of Biological Chemistry. 285 (44): 33602-33613. doi:10.1074/jbc. ... Eloranta JJ, Zaïr ZM, Hiller C, Häusler S, Stieger B, Kullak-Ublick GA (November 2009). "Vitamin D3 and its nuclear receptor ...

"Cyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and mitochondrial function". Proceedings ... Baldin V, Lukas J, Marcote MJ, Pagano M, Draetta G (May 1993). "Cyclin D1 is a nuclear protein required for cell cycle ... Adnane J, Shao Z, Robbins PD (January 1999). "Cyclin D1 associates with the TBP-associated factor TAF(II)250 to regulate Sp1- ... Ratineau C, Petry MW, Mutoh H, Leiter AB (March 2002). "Cyclin D1 represses the basic helix-loop-helix transcription factor, ...

Lancet 1986;i:242-245.PMID 2418322 Barnes PJ, Karin M. Nuclear factor-κB: a pivotal transcription factor in chronic ... He has edited or co-edited over 50 books on asthma, COPD and respiratory pharmacology. His Web of Science h-index is over 200 ... In 1987 he was appointed to the established chair of thoracic medicine at NHLI and was head of respiratory medicine at Imperial ... Sir Peter John Barnes, FRCP, FCCP, FMedSci, FRS (born 29 October 1946) is a British respiratory scientist and clinician, a ...

Since NFE2L1 is referred to as Nrf1, it is often confused with nuclear respiratory factor 1 (Nrf1). NFE2L1 is a cap 'n' collar ... Nuclear factor erythroid 2-related factor 1 (Nrf1) also known as nuclear factor erythroid-2-like 1 (NFE2L1) is a protein that ... "The Fbw7 tumor suppressor regulates nuclear factor E2-related factor 1 transcription factor turnover through proteasome- ... Oh DH, Rigas D, Cho A, Chan JY (Nov 2012). "Deficiency in the nuclear-related factor erythroid 2 transcription factor (Nrf1) ...

2002). "Mutation of a nuclear respiratory factor 2 binding site in the 5' untranslated region of the ADSL gene in three ... Gugneja S, Virbasius CM, Scarpulla RC (1996). "Nuclear respiratory factors 1 and 2 utilize similar glutamine-containing ... non-DNA-binding subunits of human nuclear respiratory factor 2 share a conserved transcriptional activation domain". Mol. Cell ... 1997). "Functional domains of transcription factor hGABP beta1/E4TF1-53 required for nuclear localization and transcription ...

... by Nuclear Respiratory Factors (NRF-1 and NRF-2) and PGC-1 Family Coactivators". Mol. Cell. Biol. 25 (4): 1354-66. doi:10.1128/ ... a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 ( ... Serum-Inducible Coactivator of Nuclear Respiratory Factor 1-Dependent Transcription in Mammalian Cells". Mol Cell Biol. 21 (11 ... 2004). "SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic ...

... and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of ... serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells". Mol. Cell. Biol. 21 ( ... Fu M, Zhang J, Lin Y, Zhu X, Ehrengruber MU, Chen YE (July 2002). "Early growth response factor-1 is a critical transcriptional ... This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This ...

Several factors had to be considered in redevelopment. New specialties needed to be accommodated: neurology, coronary care, ... renal dialysis, respiratory research, vascular surgery, radiotherapy and nuclear medicine. Care in the community and district ... 48 During World War I hospital facilities were severely strained by several factors: soldiers from the Trentham Military Camp ...

"Increased expression of mitochondrial transcription factor A and nuclear respiratory factor-1 in skeletal muscle from aged ... Mitochondrial transcription factor A, abbreviated as TFAM or mtTFA, is a protein that in humans is encoded by the TFAM gene. ... Ngo, HB; Kaiser, JT; Chan, DC (30 October 2011). "The mitochondrial transcription and packaging factor Tfam imposes a U-turn on ... This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a ...

Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in ... Guo A, Nie F, Wong-Riley M (Feb 2000). "Human nuclear respiratory factor 2 alpha subunit cDNA: isolation, subcloning, ... GABPA has been shown to interact with Host cell factor C1, Sp1 transcription factor and Sp3 transcription factor. ETS ... non-DNA-binding subunits of human nuclear respiratory factor 2 share a conserved transcriptional activation domain". Molecular ...

... of hepatocyte nuclear factor/forkhead homologue 4 and characterization of gene expression in the developing respiratory and ... "Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain ... Murphy DB, Seemann S, Wiese S, Kirschner R, Grzeschik KH, Thies U (March 1997). "The human hepatocyte nuclear factor 3/fork ... You Y, Huang T, Richer EJ, Schmidt JE, Zabner J, Borok Z, Brody SL (April 2004). "Role of f-box factor foxj1 in differentiation ...

... by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators". Mol. Cell. Biol. 25 (4): 1354-66. doi:10.1128/ ... 2002). "Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA". Nat. Genet. 31 (3): 289-94. doi: ... 2002). "Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA". Nat. Genet. 31 (3): 289-94. doi: ... 2002). "Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA". Nat. Genet. 31 (3): 289-94. doi: ...

It is known to co-activate nuclear respiratory factor 2 (NRF2/GABPA), and together with NRF-2 coactivates nuclear respiratory ... activate the mitochondrial transcription factor A (tfam), which is directly responsible for transcribing nuclear-encoded ... c-Myc, a transcription factor, can be inhibited during its dimerization with Max protein by molecules such as IIA6B17 and ... Mitochondria are produced from the transcription and translation of genes both in the nuclear genome and in the mitochondrial ...

... and nuclear respiratory factors (NRFs)[citation needed]. PGC-1α provides a direct link between external physiological stimuli ... It is known to be activated by a host of factors, including: Reactive oxygen species and reactive nitrogen species, both formed ... This protein interacts with the nuclear receptor PPAR-γ, which permits the interaction of this protein with multiple ... regulates triglyceride metabolism by activation of the nuclear receptor FXR". Genes Dev. 18 (2): 157-69. doi:10.1101/gad. ...

... by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators". Mol. Cell. Biol. 25 (4): 1354-66. doi:10.1128/ ... 2002). "Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA". Nat. Genet. 31 (3): 289-94. doi: ... This protein is a transcription initiation factor for the mitochondrial RNA polymerase, POLRMT. Its paralog TFB1M can perform a ... Dimethyladenosine transferase 2; transcription factor B2, mitochondrial is an enzyme that in humans is encoded by the TFB2M ...

Marie S, Race V, Nassogne MC, Vincent MF, Van den Berghe G (Jul 2002). "Mutation of a nuclear respiratory factor 2 binding site ...

p53 clearly has two functions: one a nuclear role as a transcription factor, and the other a cytoplasmic role in regulating the ... p53 has been shown to regulate the shift from the respiratory to the glycolytic pathway. However, a mutation can damage the ... One key factor in healing is the regulation of cytokine gene expression, which enables complementary groups of cells to respond ... In addition, environmental factors such as carcinogens and radiation cause mutations that may contribute to the development of ...

... and nuclear factor kappa B (NF-κB), resulting in an antiviral state. Respiratory epithelial cells induce mitochondrial ROS in ... ROS then activate various transcription factors such as nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB ... The production of ROS is strongly influenced by stress factor responses in plants, these factors that increase ROS production ... After growth factor stimulation of RTKs, ROS can trigger activation of signaling pathways involved in cell migration and ...

A yeast nuclear gene (ATP10) encodes a product that is essential for the assembly of a functional mitochondrial ATPase complex ... Mutations in ATP10 induce a loss of rutamycin sensitivity in the mitochondrial ATPase, but do not affect the respiratory ... In molecular biology, ATP10 protein (mitochondrial ATPase complex subunit ATP10) is an ATP synthase assembly factor. It is ... Ackerman SH, Tzagoloff A (June 1990). "ATP10, a yeast nuclear gene required for the assembly of the mitochondrial F1-F0 complex ...

... it enhances the activity of transcription factors like nuclear respiratory factor 1 (NRF-1), myocyte enhancer factor 2 (MEF2), ... In the liver, AMPK inhibits gluconeogenesis by inhibiting transcription factors including hepatocyte nuclear factor 4 (HNF4) ... It is also regulated by several protein-protein interactions, and may either be activated or inhibited by oxidative factors; ... Two proteins are essential for the regulation of GLUT-4 expression at a transcriptional level - myocyte enhancer factor 2 (MEF2 ...

"Respiratory Syncytial Virus-Induced RANTES Production from Human Bronchial Epithelial Cells Is Dependent on Nuclear Factor-κB ... Nuclear Binding and Is Inhibited by Adenovirus-Mediated Expression of Inhibitor of κBα". Journal of Immunology. 161 (2): 1007- ...

... stimulate the anti-apoptoic factor Bcl-2 due to reactive oxygen species dependent transcriptional activation of nuclear factor ... Blarcamesine inhibits mitochondrial respiratory dysfunction and therefore prevents against oxidative stress and apoptosis. This ...

This causes the nuclear factor erythroid 2-related factor 2 (Nrf2)-regulated response pathway to induce antioxidant responses. ... 3-MC may cause respiratory tract irritation, skin irritation or eye irritation. 3-MC is mutagenic to human cells. Curren et al ...

Protein complex co-immunoprecipitation (Co-IP) experiments revealed interacting protein NRF1 nuclear respiratory factor 1 This ... as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear ...