The nuclear receptor 4A1 (NR4A1 for "nuclear receptor subfamily 4 group A member 1") also known as Nur77, TR3, and NGFI-B is a ... The other two members are Nuclear receptor 4A2 (NR4A2) and Nuclear receptor 4A3 (NR4A3). Nuclear receptor 4A1 has a high degree ... "Entrez Gene: NR4A1 nuclear receptor subfamily 4, group A, member 1". Chang C, Kokontis J, Liao SS, Chang Y (1989). "Isolation ... Nuclear receptor 4A1 (NR4A1) is a member of the NR4A nuclear receptor family of intracellular transcription factors. NR4A1 is ...
... group H, member 2). The liver X receptors (LXRs) were originally identified as orphan members of the nuclear receptor ... "Entrez Gene: NR1H2 nuclear receptor subfamily 1, group H, member 2". Song C, Hiipakka RA, Kokontis JM, Liao S (Jun 1995). " ... is a member of the nuclear receptor family of transcription factors. LXR-β is encoded by the NR1H2 gene (nuclear receptor ... a new member of the gene family encoding the human steroid hormone nuclear receptor". Gene. 147 (2): 273-6. doi:10.1016/0378- ...
... group H, member 4), is a nuclear receptor that is encoded by the NR1H4 gene in humans. FXR is expressed at high levels in the ... The bile acid receptor (BAR), also known as farnesoid X receptor (FXR) or NR1H4 (nuclear receptor subfamily 1, ... "Entrez Gene: NR1H4 nuclear receptor subfamily 1, group H, member 4". Forman BM, Goode E, Chen J, Oro AE, Bradley DJ, Perlmann T ... "Farnesoid X Receptor (NR1H4)". Nuclear Receptor Resource. Archived from the original on 2015-01-12. Retrieved 2015-01-12. ...
... group I, member 3 is a protein that in humans is encoded by the NR1I3 gene. CAR is a member of the nuclear receptor superfamily ... The constitutive androstane receptor (CAR) also known as nuclear receptor subfamily 1, ... CAR is a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. Unlike ... Baes M, Gulick T, Choi HS, Martinoli MG, Simha D, Moore DD (Mar 1994). "A new orphan member of the nuclear hormone receptor ...
... group I, member 2 (NR1I2) is a protein that in humans is encoded by the NR1I2 (nuclear Receptor subfamily 1, group I, member 2 ... also known as the steroid and xenobiotic sensing nuclear receptor (SXR) or nuclear receptor subfamily 1, ... "Entrez Gene: NR1I2 nuclear receptor subfamily 1, group I, member 2". Ricketts ML, Boekschoten MV, Kreeft AJ, Hooiveld GJ, Moen ... PXR belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding ...
The testicular receptor 2 (TR2) also known as NR2C1 (nuclear receptor subfamily 2, group C, member 1) is protein that in humans ... "Entrez Gene: NR2C1 nuclear receptor subfamily 2, group C, member 1". Chang C, Kokontis J, Acakpo-Satchivi L, Liao S, Takeda H, ... TR2 is a member of the nuclear receptor family of transcription factors. Testicular receptor 2 has been shown to interact with ... Lee CH, Chinpaisal C, Wei LN (Sep 1998). "A novel nuclear receptor heterodimerization pathway mediated by orphan receptors TR2 ...
"Entrez Gene: NR2F1 nuclear receptor subfamily 2, group F, member 1". Qiu Y, Krishnan V, Zeng Z, Gilbert DJ, Copeland NG, Gibson ... Nuclear Receptor subfamily 2, group F, member 1) is a protein that in humans is encoded by the NR2F1 gene. This protein is a ... member of nuclear hormone receptor family of steroid hormone receptors. Coup (chicken ovalbumin upstream promoter) ... a highly conserved protein with characteristics of a corepressor for members of the nuclear hormone receptor superfamily". ...
... is a nuclear receptor protein that in humans is encoded by the NR0B1 gene (nuclear receptor subfamily 0, group B, member 1). ... "Entrez Gene: NR0B1 nuclear receptor subfamily 0, group B, member 1". Walker AP, Chelly J, Love DR, Brush YI, Récan D, Chaussain ... "An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita". Nature. ... This gene encodes a protein that lacks the normal DNA-binding domain contained in other nuclear receptors. The encoded protein ...
... has been shown to activate expression of Nuclear receptor subfamily 5 group A member 1 (NR5A1). NR5A1 is involved in ... KIAA1257 is predicted to be localized to the nucleus and contains several nuclear localization signals. A summary of KIAA1257 ... Table 1 The protein KIAA1257 exists most commonly as a translation of the mRNA isoform X4, which is only half the length of ... flanked by Ras-related protein Rab-43 and several pseudogenes and on the opposite strand Acyl CoA dehydrogenase family member 9 ...
... retinoid receptor-related testis-associated receptor) or NR6A1 (nuclear receptor subfamily 6, group A, member 1), is a protein ... "Entrez Gene: NR6A1 nuclear receptor subfamily 6, group A, member 1". Knoll A, Schröpfer S, Puchta H. The RTR complex as ... of the repressor function of the nuclear orphan receptor retinoid receptor-related testis-associated receptor/germ cell nuclear ... binding properties of the nuclear orphan receptor germ cell nuclear factor/retinoid receptor-related testis-associated receptor ...
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein ... group F, member 2) is a nuclear receptor that in humans is encoded by the RORB gene. ... RAR-related orphan receptor beta (ROR-beta), also known as NR1F2 (nuclear receptor subfamily 1, ... nucleotide diphosphate kinase NM23 specifically interacts with members of the ROR/RZR nuclear orphan receptor subfamily". ...
... (PPAR-α), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1 ... PPAR-alpha is part of the subfamily of peroxisome proliferator-activated receptors. It was the first member of the PPAR family ... "Identification of nuclear receptor corepressor as a peroxisome proliferator-activated receptor alpha interacting protein". J. ... "The orphan nuclear hormone receptor LXR alpha interacts with the peroxisome proliferator-activated receptor and inhibits ...
... group B, member 3) is a nuclear receptor encoded by the RARG gene. Adapalene selectively targets retinoic acid receptor beta ... Retinoic acid receptor gamma (RAR-γ), also known as NR1B3 (nuclear receptor subfamily 1, ... "Identification of nuclear receptor corepressor as a peroxisome proliferator-activated receptor alpha interacting protein". The ... Retinoic acid receptor gamma has been shown to interact with NCOR1. Retinoic acid receptor GRCh38: Ensembl release 89: ...
... but it is closely related to other members of the nuclear receptor family and is functionally related to other nuclear receptor ... Rev-Erb beta (Rev-Erbβ), also known as nuclear receptor subfamily 1 group D member 2 (NR1D2), is a member of the Rev-Erb ... In mammals, the NR1D2 (nuclear receptor subfamily 1 group D member 2) gene encodes the protein Rev-Erbβ. Unlike NR1D1, the ... Enmark E, Kainu T, Pelto-Huikko M, Gustafsson JA (October 1994). "Identification of a novel member of the nuclear receptor ...
Nuclear receptor subfamily 5 group A member 1 (NR5A1), also known as SF1 or Ad4BP (MIM 184757), is located on the long arm of ... Shen, Wen-Hui; Moore, Chris C.D.; Ikeda, Yayoi; Parker, Keith L.; Ingraham, Holly A. (June 1994). "Nuclear receptor ... The NR5A1 is an orphan nuclear receptor that was first identified following the search for a common regulator of the cytochrome ... This receptor is a pivotal transcriptional regulator of an array of genes involved in reproduction, steroidogenesis and male ...
The glucocorticoid receptor (GR or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor ... The unbound receptor resides in the cytosol of the cell. After the receptor is bound to glucocorticoid, the receptor- ... a nuclear protein that interacts with and regulates transcriptional activity of androgen receptor and glucocorticoid receptor ... Kumar R, Thompson EB (May 1999). "The structure of the nuclear hormone receptors". Steroids. 64 (5): 310-319. doi:10.1016/S0039 ...
NR4A1 (nuclear receptor subfamily 4, group A, member 1) - This gene encodes nerve growth factor IB that is a member of the ... OR7E47P (olfactory receptor, family 7, subfamily E, member 47 pseudogene) - Olfactory receptors interact with odorant molecules ... The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding- ... Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are ...
... is a nuclear receptor protein that in humans is encoded by the NR1H3 gene (nuclear receptor subfamily 1, group H, member 3). ... The liver X receptors, LXRα (this protein) and LXRβ, form a subfamily of the nuclear receptor superfamily and are key ... "Entrez Gene: nuclear receptor subfamily 1". Gupta DS, Kaul D, Kanwar AJ, Parsad D (Jan 2010). "Psoriasis: crucial role of LXR- ... "The orphan nuclear hormone receptor LXR alpha interacts with the peroxisome proliferator-activated receptor and inhibits ...
The nuclear receptor 4A3 (NR4A3) (nuclear receptor subfamily 4, group A, member 3) also known as neuron-derived orphan receptor ... NR4A3 is a member of the nuclear receptor family of intracellular transcription factors. NR4A3 plays a central regulatory role ... Pearen MA, Ryall JG, Maxwell MA, Ohkura N, Lynch GS, Muscat GE (Nov 2006). "The orphan nuclear receptor, NOR-1, is a target of ... Pearen MA, Ryall JG, Maxwell MA, Ohkura N, Lynch GS, Muscat GE (Nov 2006). "The orphan nuclear receptor, NOR-1, is a target of ...
... (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types ... March 2001). "A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N- ... "The aryl hydrocarbon receptor interacts with estrogen receptor alpha and orphan receptors COUP-TFI and ERRalpha1". Archives of ... L'Horset F, Dauvois S, Heery DM, Cavaillès V, Parker MG (November 1996). "RIP-140 interacts with multiple nuclear receptors by ...
The nuclear receptor 4A2 (NR4A2) (nuclear receptor subfamily 4 group A member 2) also known as nuclear receptor related 1 ... "Entrez Gene: NR4A2 nuclear receptor subfamily 4, group A, member 2". Yi SH, He XB, Rhee YH, Park CH, Takizawa T, Nakashima K, ... NR4A2 is a member of the nuclear receptor family of intracellular transcription factors. NR4A2 plays a key role in the ... Nurr1+nuclear+receptor at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Articles with short ...
... nuclear receptor subfamily 5, group A, member 2) is a protein that in humans is encoded by the NR5A2 gene. LRH-1 is a member of ... Peng N, Kim JW, Rainey WE, Carr BR, Attia GR (Dec 2003). "The role of the orphan nuclear receptor, liver receptor homologue-1, ... Luo Y, Liang CP, Tall AR (Jul 2001). "The orphan nuclear receptor LRH-1 potentiates the sterol-mediated induction of the human ... Nitta M, Ku S, Brown C, Okamoto AY, Shan B (Jun 1999). "CPF: an orphan nuclear receptor that regulates liver-specific ...
... group B, member 2) is a nuclear receptor that in humans is encoded by the RARB gene. This gene encodes retinoic acid receptor ... Retinoic acid receptor beta (RAR-beta), also known as NR1B2 (nuclear receptor subfamily 1, ... a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to ... Retinoic acid receptor beta has been shown to interact with NR4A2. Retinoic acid receptor GRCh38: Ensembl release 89: ...
... (HNF4A) also known as NR2A1 (nuclear receptor subfamily 2, group A, member 1) is a nuclear ... "The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms ... "Exclusive homodimerization of the orphan receptor hepatocyte nuclear factor 4 defines a new subclass of nuclear receptors". ... dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4". ...
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. In humans, 4 isoforms of RORα ... "The orphan nuclear receptor RORα and group 3 innate lymphoid cells drive fibrosis in a mouse model of Crohn's disease". Science ... RAR-related orphan receptor alpha (RORα), also known as NR1F1 (nuclear receptor subfamily 1, group F, member 1) is a nuclear ... nucleotide diphosphate kinase NM23 specifically interacts with members of the ROR/RZR nuclear orphan receptor subfamily". ...
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form ... group C, member 3) is a type II nuclear receptor functioning as a transcription factor that in humans is encoded by the PPARG ... also known as the glitazone reverse insulin resistance receptor, or NR1C3 (nuclear receptor subfamily 1, ... January 2002). "Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor ...
... (RXR-alpha), also known as NR2B1 (nuclear receptor subfamily 2, group B, member 1) is a nuclear ... Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of ... "The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms ... Kliewer SA, Umesono K, Mangelsdorf DJ, Evans RM (January 1992). "Retinoid X receptor interacts with nuclear receptors in ...
Nuclear receptor subfamily 2 group E member 1) is a protein that in humans is encoded by the NR2E1 gene. TLX is a member of the ... nuclear receptor family of intracellular transcription factors. TLX regulates the expression of another nuclear receptor, RAR. ... "Cell-type-specific regulation of the retinoic acid receptor mediated by the orphan nuclear receptor TLX". Molecular and ... "Cell-type-specific regulation of the retinoic acid receptor mediated by the orphan nuclear receptor TLX". Molecular and ...
... (TR-alpha) also known as nuclear receptor subfamily 1, group A, member 1 (NR1A1), is a nuclear ... a highly conserved protein with characteristics of a corepressor for members of the nuclear hormone receptor superfamily". ... The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for ... interactions of thyroid hormone receptor with retinoid-X receptor, nuclear factor kappa B, Sp1, and Tat". Transactions of the ...
SMAD family member 7, nuclear receptor subfamily 4 group A member 1, and homeobox protein SIX3, and represses BCL11B as well as ... The novel sequence harbors a nuclear receptor binding motif LXXLL which confers MTA1 with an ability to interact with estrogen ... receptor alpha or other type I nuclear receptors. The ZG29p variant represents the c-terminal MTA1 with two proline-rich SH3 ... Kumar R, Gururaj AE (2008). "Coregulators as Oncogenes and Tumor Suppressors". In O'Malley BW, Kumar R (eds.). Nuclear Receptor ...