"Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor". Nature. 377 (6548 ... The nuclear receptor co-repressor 2 (NCOR2) is a transcriptional coregulatory protein that contains several nuclear receptor- ... Chen JD, Evans RM (October 1995). "A transcriptional co-repressor that interacts with nuclear hormone receptors". Nature. 377 ( ... Chen JD, Evans RM (October 1995). "A transcriptional co-repressor that interacts with nuclear hormone receptors". Nature. 377 ( ...
The nuclear receptor co-repressor 1 also known as thyroid-hormone- and retinoic-acid-receptor-associated co-repressor 1 (TRAC-1 ... Nuclear receptor co-repressor 1 has been shown to interact with: Androgen receptor, CHD1, Calcitriol receptor GPS2, ... "Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor". Nature. 377 (6548 ... Tagami T, Lutz WH, Kumar R, Jameson JL (December 1998). "The interaction of the vitamin D receptor with nuclear receptor ...
"AHRR aryl-hydrocarbon receptor repressor [Homo sapiens (Human)] - Gene - NCBI". "NCOA2 nuclear receptor coactivator 2 [Homo ... The AHRR gene (i.e. gene for the aryl hydrocarbon receptor repressor protein) is located at band 15.33 on the short (or "p") ... gene for the nuclear receptor coactivator 2 protein) is located at band 13.3 on the long (or "q") arm of chromosome 8 (cite ... of AFST tissues detect cells bearing estrogen receptor, CD163 and NCOA2 proteins in 100% of cases; MUC1 (also termed EMA) ...
2004). "TIP27: a novel repressor of the nuclear orphan receptor TAK1/TR4". Nucleic Acids Res. 32 (14): 4194-204. doi:10.1093/ ... This gene encodes a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. ... 363 (2): 166-176. doi:10.1056/NEJMra0905980. PMID 20647212. Koontz JI, Soreng AL, Nucci M, et al. (2001). "Frequent fusion of ... 28 (2): 224-32. doi:10.1097/00000478-200402000-00010. PMID 15043312. S2CID 21043514. Nakajima T, Fujino S, Nakanishi G, et al ...
Klinge CM (May 2000). "Estrogen receptor interaction with co-activators and co-repressors". Steroids. 65 (5): 227-51. doi: ... These nuclear receptors are considered orphan receptors, as their endogenous ligands are still unknown. The nuclear receptor/ ... nuclear receptors led to the construction of a phylogenic tree of nuclear receptor that indicated that all nuclear receptors ... approved drugs target nuclear receptors. A number of nuclear receptors, referred to as orphan receptors, have no known (or at ...
... has been shown to interact with HDAC1, SRA1 and Nuclear receptor co-repressor 2. GRCh38: Ensembl release 89: ... In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; ... an integrator of transcriptional repression and nuclear receptor signaling". Proc. Natl. Acad. Sci. U.S.A. 99 (5): 2613-8. ... an inducible cofactor that integrates nuclear receptor repression and activation". Genes Dev. 15 (9): 1140-51. doi:10.1101/gad. ...
"An embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer". The EMBO Journal. 21 (13 ... TR2 is a member of the nuclear receptor family of transcription factors. Testicular receptor 2 has been shown to interact with ... Lee CH, Chinpaisal C, Wei LN (Sep 1998). "A novel nuclear receptor heterodimerization pathway mediated by orphan receptors TR2 ... "A constitutive nuclear localization signal from the second zinc-finger of orphan nuclear receptor TR2". The Journal of ...
You SH, Lim HW, Sun Z, Broache M, Won KJ, Lazar MA (February 2013). "Nuclear receptor co-repressors are required for the ... 280 (2): 192-200. doi:10.1016/j.canlet.2009.03.013. PMID 19345475. Patil V, Sodji QH, Kornacki JR, Mrksich M, Oyelere AK (May ... Within the Class I HDACs, HDAC 1, 2, and 3 are found primarily in the nucleus, whereas HDAC8 is found in both the nucleus and ... 20 (2): 182-187. doi:10.1038/nsmb.2476. PMC 3565028. PMID 23292142. Marks PA, Xu WS (July 2009). "Histone deacetylase ...
5 (2): R8. doi:10.1186/gb-2004-5-2-r8. PMC 395752. PMID 14759258. Osada H, Tatematsu Y, Saito H, et al. (2004). "Reduced ... HDAC10 has been shown to interact with Histone deacetylase 2 and Nuclear receptor co-repressor 2. Histone deacetylase GRCh38: ...
... has been shown to interact with Sirtuin 1 and Nuclear receptor co-repressor 1. GRCh38: Ensembl release 89: ENSG00000135547 ... Takata T, Ishikawa F (January 2003). "Human Sir2-related protein SIRT1 associates with the bHLH repressors HES1 and HEY2 and is ... Takata T, Ishikawa F (January 2003). "Human Sir2-related protein SIRT1 associates with the bHLH repressors HES1 and HEY2 and is ... In this mechanism, adjacent cells bind via transmembrane notch receptors. Two similar and redundant genes in mouse are required ...
ING1 and Nuclear receptor co-repressor 1, RBBP4, RBBP7, SIN3A, and YY1. GRCh38: Ensembl release 89: ENSG00000164105 - Ensembl, ... Underhill C, Qutob MS, Yee SP, Torchia J (December 2000). "A novel nuclear receptor corepressor complex, N-CoR, contains ... Underhill C, Qutob MS, Yee SP, Torchia J (December 2000). "A novel nuclear receptor corepressor complex, N-CoR, contains ... The DNA binding of SAP30 proteins is regulated by the nuclear signalling lipids, phosphoinositides (PI). SAP30 proteins provide ...
In the absence of hormone, TR forms a complex with corepressor proteins such as nuclear receptor co-repressor 1 (N-CoR) and 2 ( ... heterodimers with other nuclear receptors, or homodimers. Dimerizing with different nuclear receptors leads to the regulation ... The thyroid hormone receptor (TR) is a type of nuclear receptor that is activated by binding thyroid hormone. TRs act as ... THR commonly interacts with the retinoid X receptor (RXR), a nuclear retinoic acid receptor. TR/RXR heterodimers are the most ...
Chen JD, Evans RM (October 1995). "A transcriptional co-repressor that interacts with nuclear hormone receptors". Nature. 377 ( ... Retinoic acid receptor alpha (RAR-α), also known as NR1B1 (nuclear receptor subfamily 1, group B, member 1) is a nuclear ... RARA codes for the nuclear hormone receptor retinoic acid receptor, alpha subtype, a transcription factor. There are another ... Kliewer SA, Umesono K, Mangelsdorf DJ, Evans RM (January 1992). "Retinoid X receptor interacts with nuclear receptors in ...
NCoR (nuclear receptor co-repressor) directly binds to the D and E domains of nuclear receptors and represses their ... Lazar MA (2003). "Nuclear receptor corepressors". Nucl Recept Signal. 1: e001. doi:10.1621/nrs.01001. PMC 1402229. PMID ... Christian, Mark; White, Roger; Parker, Malcolm G. (August 2006). "Metabolic regulation by the nuclear receptor corepressor ... Privalsky, Martin L. (March 2004). "The Role of Corepressors in Transcriptional Regulation by Nuclear Hormone Receptors". ...
It self-dimerizes into, by default, a repressor state. Computer simulations based on this model shows that a ligand could ... The photoreceptor cell-specific nuclear receptor (PNR), also known as NR2E3 (nuclear receptor subfamily 2, group E, member 3), ... January 2002). "The nuclear receptor NR2E3 plays a role in human retinal photoreceptor differentiation and degeneration". ... January 2002). "The nuclear receptor NR2E3 plays a role in human retinal photoreceptor differentiation and degeneration". ...
Nuclear receptor co-repressor 2, Promyelocytic leukemia protein, Retinoid X receptor alpha, and Von Hippel-Lindau tumor ... The other two members are Nuclear receptor 4A2 (NR4A2) and Nuclear receptor 4A3 (NR4A3). Nuclear receptor 4A1 has a high degree ... The nuclear receptor 4A1 (NR4A1 for "nuclear receptor subfamily 4 group A member 1") also known as Nur77, TR3, and NGFI-B is a ... orphan+nuclear+receptor+NGFI-B at the U.S. National Library of Medicine Medical Subject Headings (MeSH) orphan+nuclear+receptor ...
... has been shown to interact with: KLF9, Nuclear receptor co-repressor 2, and UBE3A. Membrane progesterone ... The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found ... a member of the steroid-receptor superfamily of nuclear receptors. The single-copy human (hPR) gene uses separate promoters and ... Thénot S, Henriquet C, Rochefort H, Cavaillès V (May 1997). "Differential interaction of nuclear receptors with the putative ...
Nuclear receptor co-repressor 2, Promyelocytic leukemia protein and Src, and TEAD1. MKL1 Nuclear actin functions GRCh38: ... "Serum response factor-GATA ternary complex required for nuclear signaling by a G-protein-coupled receptor". Mol. Cell. Biol. 21 ... Matsuzaki K, Minami T, Tojo M, Honda Y, Saitoh N, Nagahiro S, Saya H, Nakao M (March 2003). "PML-nuclear bodies are involved in ... Lee SK, Kim JH, Lee YC, Cheong J, Lee JW (April 2000). "Silencing mediator of retinoic acid and thyroid hormone receptors, as a ...
Nuclear receptor co-repressor 1, Nuclear receptor co-repressor 2, PRKAR2A, and Zinc finger and BTB domain-containing protein 16 ... "Interactions between the leukaemia-associated ETO homologues of nuclear repressor proteins". Eur. J. Haematol. 71 (6): 439-47. ... McGhee L, Bryan J, Elliott L, Grimes HL, Kazanjian A, Davis JN, Meyers S (August 2003). "Gfi-1 attaches to the nuclear matrix, ... Odaka Y, Mally A, Elliott LT, Meyers S (2000). "Nuclear import and subnuclear localization of the proto-oncoprotein ETO (MTG8 ...
Nuclear receptor CO-Repressor (NCOR) NCOR1 (NCOR1) NCOR2 (NCOR2)/SMRT (Silencing Mediator (co-repressor) for Retinoid and ... Nuclear receptors bind to coactivators in a ligand-dependent manner. A common feature of nuclear receptor coactivators is that ... "Nuclear Receptor Signaling Atlas (Receptors, Coactivators, Corepressors and Ligands)". The NURSA Consortium. Retrieved 2008-02- ... form of the nuclear receptor (or possibly antagonist bound receptor). CtBP 602618 SIN3A (associates with class II histone ...
Nuclear receptor co-repressor 2, POU2AF1, RELA, Retinoid X receptor alpha, SNAPC4, Sp1 transcription factor, and TATA binding ... La Boissière S, Hughes T, O'Hare P (January 1999). "HCF-dependent nuclear import of VP16". EMBO J. 18 (2): 480-9. doi:10.1093/ ... La Boissière S, Hughes T, O'Hare P (1999). "HCF-dependent nuclear import of VP16". EMBO J. 18 (2): 480-9. doi:10.1093/emboj/ ... retinoid and thyroid hormone receptors interacts with octamer transcription factor-1 and acts as a transcriptional repressor". ...
Nuclear receptor co-repressor 2, P21, PCNA, PHF21A, Prohibitin, Promyelocytic leukemia protein, RAD9A, RBBP4, RBBP7, RCOR1, ... "Dual mechanisms of regulation of transcription of luteinizing hormone receptor gene by nuclear orphan receptors and histone ... "Dual mechanisms of regulation of transcription of luteinizing hormone receptor gene by nuclear orphan receptors and histone ... Zhang J, Kalkum M, Chait BT, Roeder RG (March 2002). "The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK ...
Nuclear receptor co-repressor 2, OGT, PHF12, Promyelocytic leukemia protein, RBBP4, RBBP7, SAP130, SAP30, SMARCA2, SMARCA4, ... "Dual mechanisms of regulation of transcription of luteinizing hormone receptor gene by nuclear orphan receptors and histone ... "Dual mechanisms of regulation of transcription of luteinizing hormone receptor gene by nuclear orphan receptors and histone ... Zhang J, Kalkum M, Chait BT, Roeder RG (March 2002). "The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK ...
Nuclear receptor co-repressor 1, Nuclear receptor co-repressor 2, P53, RPL11, Retinoblastoma protein, Retinoic acid receptor ... This forms a ring-like structure that binds to the nuclear matrix, forming a PML-Nuclear body (PML-NB). The edge of the ring- ... PML protein is a tumor suppressor protein required for the assembly of a number of nuclear structures, called PML-nuclear ... "Leukemia-associated retinoic acid receptor alpha fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodies ...
NCOR may also refer to: Nuclear receptor co-repressor 1 (NCOR1), a protein Nuclear receptor co-repressor 2 (NCOR2), a protein ...
NOTCH1 Nuclear receptor co-repressor 2, Nuclear receptor coactivator 1, PABPN1, RBPJ, Retinoblastoma protein, and SKI protein. ... This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D ... a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300". Biochemical and Biophysical Research ... and retinoid X receptor with vitamin D receptor helix H10 residues". The Journal of Biological Chemistry. 278 (10): 8224-8. doi ...
Nuclear receptor co-repressor 2, Promyelocytic leukemia protein RUNX1T1, Retinoic acid receptor alpha, SIN3A, SIN3B, and ZBTB32 ... Guidez F, Ivins S, Zhu J, Söderström M, Waxman S, Zelent A (1998). "Reduced retinoic acid-sensitivities of nuclear receptor ... 1997). "Leukemia-associated retinoic acid receptor α fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear ... Zinc finger and BTB domain-containing protein 16 has been shown to interact with: Angiotensin II receptor type 1, BCL6, BMI1, ...
Nuclear receptor co-repressor 1, Nuclear receptor co-repressor 2, Testicular receptor 2, YWHAB, YWHAE, and Zinc finger and BTB ... Franco PJ, Farooqui M, Seto E, Wei LN (August 2001). "The orphan nuclear receptor TR2 interacts directly with both class I and ... Huang EY, Zhang J, Miska EA, Guenther MG, Kouzarides T, Lazar MA (January 2000). "Nuclear receptor corepressors partner with ... Franco PJ, Li G, Wei LN (August 2003). "Interaction of nuclear receptor zinc finger DNA binding domains with histone ...
Chen JD, Evans RM (Oct 1995). "A transcriptional co-repressor that interacts with nuclear hormone receptors". Nature. 377 (6548 ... Thyroid hormone receptor alpha (TR-alpha) also known as nuclear receptor subfamily 1, group A, member 1 (NR1A1), is a nuclear ... The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for ... interactions of thyroid hormone receptor with retinoid-X receptor, nuclear factor kappa B, Sp1, and Tat". Transactions of the ...
... nuclear receptor-interacting factor 3-S28, SRC3-delta4-T56-S659-676, beta-catenin-S675, BAD-S111, BAD-S112, S136, MEK1-S298, ... SMART/HDAC1-associated repressor protein-S3486-T3568, Tubulin Cofactor B-S65-S128, Snail-S246 vascular endothelial-cadherin- ... Ku GM, Yablonski D, Manser E, Lim L, Weiss A (February 2001). "A PAK1-PIX-PKL complex is activated by the T-cell receptor ... Singh RR, Song C, Yang Z, Kumar R (May 2005). "Nuclear localization and chromatin targets of p21-activated kinase 1". The ...
"Repression of aryl hydrocarbon receptor (AHR) signaling by AHR repressor: role of DNA binding and competition for AHR nuclear ... Expression of the repressor is stimulated by the receptor/translocator heterodimer, thereby regulating receptor function ... in conjunction with the receptor's binding partner, aryl hydrocarbon receptor nuclear translocator (ARNT). The protein encoded ... The aryl-hydrocarbon receptor repressor also known as AHRR is a human gene. Dioxins and dioxin-like compounds are teratogens ...