"Entrez Gene: SAM domain, SH3 domain and nuclear localization signals 1". Retrieved 2017-09-28. Zhu YX, Benn S, Li ZH, Wei E, ... Brandt S, Ellwanger K, Beuter-Gunia C, Schuster M, Hausser A, Schmitz I, Beer-Hammer S (2010). "SLy2 targets the nuclear SAP30/ ... "The SH3-SAM adaptor HACS1 is up-regulated in B cell activation signaling cascades". J. Exp. Med. 200 (6): 737-47. doi:10.1084/ ...

Cokol M, Nair R, Rost B (November 2000). "Finding nuclear localization signals". EMBO Reports. 1 (5): 411-5. doi:10.1093/embo- ... "Analysis and prediction of leucine-rich nuclear export signals". Protein Engineering, Design & Selection. 17 (6): 527-36. doi: ... improved protein subcellular localization prediction with refined localization subcategories and predictive capabilities for ... Zhu PP, Li WC, Zhong ZJ, Deng EZ, Ding H, Chen W, Lin H (February 2015). "Predicting the subcellular localization of ...

Identification of a functional nuclear localization signal". The Journal of Biological Chemistry. 274 (40): 28405-12. doi: ... Somasekaram A, Jarmuz A, How A, Scott J, Navaratnam N (October 1999). "Intracellular localization of human cytidine deaminase. ...

The protein also has a nuclear localization signal. C6orf201 has a conserved alpha helix and a conserved beta strand in the ... In humans this gene encodes for a nuclear protein that is primarily expressed in the testis. In humans, the gene is 51,558 base ... C6orf201 is predicted to be a nuclear protein. C6orf201 has multiple predicted PKC and CKII phosphorylation sites in humans. ...

The protein even possesses one nuclear localization signal. The secondary structure of WDR53 has been predicted to be ... signal transduction, transcription regulation, apoptosis etc.). In H. sapiens, it has been shown to be highly expressed in the ...

... contains a nuclear localization signal, The135-Leu144. Secondary structure of C21orf58 is predicted to consist ... Immunocytochemistry revealed localization of C21orf58 to nucleoplasm and nuclear bodies. Presence of a nuclear localization ... suggested nuclear localization. Predictions across orthologs agreed with nuclear localization. C21orf58 is constitutively ... The predicted isoelectric point is 10.06, supporting predicted nuclear localization. Human protein C21orf58 Isoform 1 is rich ...

It includes the nuclear localization signal (NLS), the nuclear export signal (NES) and the oligomerisation domain (OD). The NLS ... Nuclear Localization Signaling (NLS) domain, residues 316-325. homo-oligomerisation domain (OD): residues 307-355. ... Mechanical signals such as hypoxia affect levels of p53 in these niche cells through the hypoxia inducible factors, HIF-1α and ... Lim ST, Chen XL, Lim Y, Hanson DA, Vo TT, Howerton K, Larocque N, Fisher SJ, Schlaepfer DD, Ilic D (January 2008). "Nuclear FAK ...

The shuttling of Rev is regulated by its nuclear localization signal and its nuclear export signal. Once Rev is inside the ... The domain also contains a nuclear localization signal. Rev's nuclear export signal is located in residues 71-82 of the C- ... A nuclear localization signal is encoded in the rev gene, which allows the Rev protein to be localized to the nucleus, where it ... containing a nuclear localization signal (NLS), allows Rev to enter the nucleus. Entry requires binding between a Rev multimer ...

This variant has a bipartite nuclear localization signal. H2B.Z is an apicomplexan specific variant that is known to interact ...

This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation. MED14 ... dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4". ... dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4". ... Wang, G; Cantin G T; Stevens J L; Berk A J (Jul 2001). "Characterization of mediator complexes from HeLa cell nuclear extract ...

This new function may involve a nuclear localization signal. Moreover, a mitochondrial localization signal is also generated. ... At prometaphase when the nuclear membrane dissociates and spindle microtubules cross over the nuclear region, survivin stays ... To determine the localization of exogenously expressed survivin-2B and survivin-deltaEx3, fusion constructs of the proteins ... The localization of the three variants (survivin, Survivin-2B, and survivin-deltaEx3) differ, however, when cotransfected ...

There is also a predicted bipartite nuclear localization signal. C16orf78 has restricted expression toward the testis, with ... protein localization predictor". Nucleic Acids Research. 35 (Web Server): W585-W587. doi:10.1093/nar/gkm259. PMC 1933216. PMID ...

The nuclear localization signal is somewhat low at 0.75. Orthologs (P. troglodytes, S. dumerili, and C. asiatica ) were used to ... The prediction for localization of ZNF337 is highest in the nucleus (nuclear) at 95.7% followed by 4.3% in the mitochondria ( ... Thus, ZNF337 is predicted to have no N-terminal signal peptide. Also, Reinhardt's method for cytoplasmic/nuclear discrimination ... A prediction for a new signal peptide is very low and negative at -3.83. The GvH is also very negative at -8.69 (with a ...

"Functional analysis of eukaryotic 20S proteasome nuclear localization signal". Experimental Cell Research. 225 (1): 67-74. doi: ... UPS proteolysis plays a major role in responses of cancer cells to stimulatory signals that are critical for the development of ... Karin M, Delhase M (February 2000). "The I kappa B kinase (IKK) and NF-kappa B: key elements of proinflammatory signalling". ... Redox Signaling. 21 (17): 2322-43. doi:10.1089/ars.2013.5823. PMC 4241867. PMID 25133688. Wang ZV, Hill JA (February 2015). " ...

It has a nuclear localization signal in the protein sequence and a miRNA target region in the mRNA sequence. FAM78B has one ... Conserved nuclear localization signal (RPKR) from aa 248-252. FAM78B is generally ubiquitously expressed and is highly ...

B1MaV has nuclear localization signals within its protein sequences. These amino acid sequences tag the protein for import into ... "Nuclear localization sequence", Wikipedia, 2019-09-19, retrieved 2019-11-27 Peña, Eduardo José; Robles Luna, Gabriel; Zanek, ... the cell's nucleus via nuclear transport mechanisms of the cell. B1MaV is translated from mRNA which is complementary to the ...

Nuclear localization signals allow proteins to be able to enter the nucleus, but many nuclear proteins possess their own. PANO1 ... Using PSORTII, 3 discrimination of nuclear localization signals were identified. Pat4 (RRRR) at position 200, Pat7 (RRRR) at ... 3 bipartite nuclear localization signals as well as arginine-rich and proline-rich regions. ... Chen MW, Wu XJ (January 2018). "SLC25A22 Promotes Proliferation and Metastasis of Osteosarcoma Cells via the PTEN Signaling ...

There is a nuclear localization signal at residues 298-301. There are also two peroxisomal targeting signals at residues 451- ... N-acetylation is predicated at the second residue; this modification affects stability and localization. There are 6 motifs ... nuclear-cytosolic transport, and transcriptional regulation. PSORTII data predicts that c14orf93 is localized to the nucleus. ...

The actin sequence does not contain a nuclear localization signal. The small size of actin (about 43 kDa) allows it to enter ... Actin is a molecule that integrates cytoplasmic and nuclear signal transduction pathways. An example is the activation of ... Nuclear actin was first noticed and described in 1977 by Clark and Merriam. Authors describe a protein present in the nuclear ... Nuclear actin exists mainly as a monomer, but can also form dynamic oligomers and short polymers. Nuclear actin organization ...

"TBX5 nuclear localization is mediated by dual cooperative intramolecular signals". Journal of Molecular and Cellular Cardiology ... The activation of Tbx5 and other T-box proteins by Hox genes activates signaling cascades that involve the Wnt signaling ... Ultimately, Tbx5 leads to the development of apical ectodermal ridge (AER) and zone of polarizing activity (ZPA) signaling ... Hatcher CJ, Goldstein MM, Mah CS, Delia CS, Basson CT (September 2000). "Identification and localization of TBX5 transcription ...

Takemoto Y, Tashiro S, Handa H, Ishii S (August 1994). "Multiple nuclear localization signals of the B-myb gene product". FEBS ... The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in ...

Multiple conserved nuclear localization signals were also predicted within the QSER1 protein by pSORT. Predictions of the QSER1 ... Nuclear localization was predicted by pSORT. This property was conserved from the human QSER1 to the coelacanth QSER1. ... This condition is associated with altered expression of genes involved in immune responses, signaling, cell growth, and ... Science Signaling. 4 (178): rs4. doi:10.1126/scisignal.2001484. PMID 21693764. S2CID 649212. Bruderer R, Tatham MH, ...

"Classical nuclear localization signals: definition, function, and interaction with importin alpha". Journal of Biological ... a multipurpose nuclear-transport receptor". Trends in Cell Biology (in English and English). 14 (9): 505-514. doi:10.1016/J.TCB ...

"Classical nuclear localization signals: definition, function, and interaction with importin alpha". The Journal of Biological ... Unlike most signal sequences, signal patches are not cleaved after sorting is complete. In addition to intrinsic signaling ... as signal peptides or signal sequences and was awarded the 1999 Nobel prize in Physiology for the same. Signal peptides serve ... the signal peptide is generally cleaved by a signal peptidase. Consequently, most mature proteins do not contain signal ...

The localization of C16orf82 within a cell has been predicted to be nuclear. A bipartite nuclear localization signal can be ... a program for detecting sorting signals in proteins and predicting their subcellular localization". Trends in Biochemical ... Human intronless genes represent a unique subset of the genome that are often involved in signaling, sperm formation, immune ...

A Nuclear Localization Signal is observed at amino acids 393-403. The NLS is highly conserved in mammals, birds, and reptiles. ... The promoter contains binding sites for Ikaros2, Nuclear Factor Y, and at least three binding sites for Pleomorphic adenoma ... FAM208b has potential for SUMOylation SUMOylation has been observed to play a role in nuclear transport, which would aid ... The peptide sequence lacks a signal sequence either at the N-terminus or internally. No transmembrane domains have been ...

A bipartite nuclear localization signal is predicted at position 128 - 143, which is highly conserved in mammalian orthologs ( ... A bipartite nuclear localization signal is predicted at position 128 - 143. The following post-translational modifications are ... shows localization in the cytosol. Immunohistochemistry imaging of human prostate tissue also suggests cytosolic localization. ... A few notable examples include: LATS2: Negatively regulates YAP1 in the Hippo signaling pathway that plays a pivotal role in ...

"Human ribosomal protein L5 contains defined nuclear localization and export signals". J. Biol. Chem. 275 (16): 12061-8. doi: ... Michael WM, Dreyfuss G (1996). "Distinct domains in ribosomal protein L5 mediate 5 S rRNA binding and nucleolar localization". ... Jäkel S, Görlich D (1998). "Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in ...

This gene encodes a protein containing four conserved nuclear localization signals. The encoded protein may function during the ... 1990). "Nance-Horan syndrome: localization within the region Xp21.1-Xp22.3 by linkage analysis". Am. J. Hum. Genet. 47 (1): 13- ... 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635-48. doi:10.1016/ ... 2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. ...

... is known to bind to the nuclear localization signal (NLS) sequence of nucleus targeted proteins. After this ... Kobe, Bostjan (1 April 1999). "Autoinhibition by an internal nuclear localization signal revealed by the crystal structure of ... "Classical Nuclear Localization Signals: Definition, Function, and Interaction with Importin α". Journal of Biological Chemistry ... binding site on the influenza a virus nucleoprotein NP is a nonconventional nuclear localization signal". Journal of Virology. ...