1,8-Naphthyridine
... is an organic compound with the formula C8H6N2. It is the most well-studied of the six isomeric ... V. P. Litvinov (2006). Advances in the Chemistry of Naphthyridines. Advances in Heterocyclic Chemistry. Vol. 91. pp. 189-300. ... Enoxacin, nalidixic acid, and trovafloxacin are 1,8-naphthyridine derivatives with antibacterial properties related to the ... With flanking nitrogen centers, 1,8-naphthyridine serves as a binucleating ligand in coordination chemistry. International ...
Gabriel-Colman rearrangement
Allen, C. F. H. (1950). "The Naphthyridines". Chemical Reviews. 47 (2): 275-305. doi:10.1021/cr60147a004. PMID 24538878. Hauser ...
Diazanaphthalene
Paudler, William W.; Kress, Thomas J. (1968). "Naphthyridine chemistry. IX. Bromination and animation of the 1,X-naphthyridines ... and phthalazine six naphthyridines with one N atom in each ring Desmond J. Brown, Jonathan A. Ellman, Edward C. Taylor: The ... Chemistry of Heterocyclic Compounds, The Naphthyridines, John Wiley & Sons, 2007. ...
Nalidixic acid
In a technical sense, it is a naphthyridone, not a quinolone: its ring structure is a 1,8-naphthyridine nucleus that contains ... Lesher GY, Froelich EJ, Gruett MD, Bailey JH, Brundage RP (September 1962). "1,8-Naphthyridine Derivatives. A New Class of ... Naphthyridines, WIN compounds, Carboxylic acids, Topoisomerase inhibitors). ...
Phthalazine
It is isomeric with other naphthyridines including quinoxaline, cinnoline and quinazoline. Phthalazine can be obtained by the ...
Cinnoline
It is isomeric with other naphthyridines including quinoxaline, phthalazine and quinazoline. The free base can be obtained as ...
Quinoxaline
It is isomeric with other naphthyridines including quinazoline, phthalazine and cinnoline. It is a colorless oil that melts ...
Extended metal atom chains
The organic ligands often pyridylamide, pyridone, naphthyridine, or their derivatives. Each metal atom is six-coordinate, ...
Dabur Research Foundation
2009). "Anticancer and immunomodulatory activities of novel 1,8-naphthyridine derivatives". Journal of Enzyme Inhibition and ...
Streptomyces albogriseolus
Li, Xiao-Ling; Xu, Min-Juan; Zhao, Yi-Lei; Xu, Jun (2010). "A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces ...
Topoisomerase inhibitor
... naphthyridines as topoisomerase I inhibitors and potential anticancer agents". J. Med. Chem. 53 (24): 8716-26. doi:10.1021/ ...
Surface plasmon resonance microscopy
DNA array is fabricated to test the G-G mismatch stabilizing properties of the naphthyridine dimer. Each of the four ... First G-G mismatch pair is stabilized by attaching it with the ligand, naphthyridine dimer, through hydrogen bonding which make ... the SPR difference image corresponding to the addition of sequence 2 in the presence of the naphthyridine dimer shows that, in ...
Riccardo Cortese
2004). "A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of ...
Pazinaclone
Reaction of 2-amino-7-chloro-1,8-naphthyridine with phthalic anhydride leads to the corresponding phthalimide. Selective ...
Camphorsulfonic acid
... naphthyridines Utilizing the Openshaw-Whittaker Hexahydrobenzo[a]quinolizinone Resolution". Heterocycles. 31 (2): 353. doi: ...
NK1 receptor antagonist
... such as an eight-membered ring introduced into the naphthyridine ring. Chemotherapy-induced emesis is a major problem in cancer ...
Anisopus mannii
A novel chemical structure, "anisopusine"- a 1,7-naphthyridine alkaloid - was extracted from the dichloromethane soluble ...
PIP4K2A
"Discovery and Characterization of the Potent and Highly Selective 1,7-Naphthyridine-Based Inhibitors BAY-091 and BAY-297 of the ...
Amfonelic acid
US patent 3590036, "Naphthyridine-3-carboxylic Acids, Their Derivatives and Preparation Thereof" Aceto MD, Botton I, Martin R, ...
Vosaroxin
... is a naphthyridine analog of the anticancer quinolone derivatives (AQDs), a class of compounds that has not been used ...
Pagoclone
... and pazinaclone both contain an isoindolone structural motif Reaction of 2-Amino-7-chloro-1,8-naphthyridine with ... "2-Amino naphthyridine derivative, its preparation and its use", issued 12 March 1996, assigned to Rhone Poulenc Rorer SA. Atack ...
Edward Sucharda
Niementowski . It included the development of synthesis of azaaromatic compounds: derivatives of pyridine, naphthyridine and ...
Quinolone antibiotic
The first generation of the quinolones began following introduction of the related, but structurally distinct naphthyridine- ...
Cefaparole
I. Synthesis and antibacterial activity of 7 beta-[D-2-[(4-hydroxy-1,5-naphthyridine-3-carbonylamino)- and (4-hydroxypyridine-3 ...
SB-334867
Naphthyridines, Ureas, All stub articles, Sedative stubs). ...
Suriclone
Naphthyridines, Piperazines, Sedatives, Dithianes, Nitrogen heterocycles, Sulfur heterocycles, Heterocyclic compounds with 2 ...
SX-3228
Naphthyridines). ...
Philasterides dicentrarchi
Other studies investigating the in vitro effects of several new synthetic compounds, including 2 naphthyridines, 2 ...
Alatrofloxacin
Naphthyridines, Carboxylic acids, All stub articles, Antibiotic stubs). ...
Silmitasertib
Among a large series of compounds built around a benzo[c]-[2,6]naphthyridine-8-carboxylic acid scaffold, CX-4945 was chosen for ... January 2011). "Discovery and SAR of 5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid (CX-4945), the first ... Naphthyridines, Orphan drugs, Protein kinase inhibitors, Carboxylic acids, Chloroarenes, All stub articles, Antineoplastic and ...