... is an organic compound with the formula C8H6N2. It is the most well-studied of the six isomeric ... V. P. Litvinov (2006). Advances in the Chemistry of Naphthyridines. Advances in Heterocyclic Chemistry. Vol. 91. pp. 189-300. ... Enoxacin, nalidixic acid, and trovafloxacin are 1,8-naphthyridine derivatives with antibacterial properties related to the ... With flanking nitrogen centers, 1,8-naphthyridine serves as a binucleating ligand in coordination chemistry. International ...
Allen, C. F. H. (1950). "The Naphthyridines". Chemical Reviews. 47 (2): 275-305. doi:10.1021/cr60147a004. PMID 24538878. Hauser ...
Paudler, William W.; Kress, Thomas J. (1968). "Naphthyridine chemistry. IX. Bromination and animation of the 1,X-naphthyridines ... and phthalazine six naphthyridines with one N atom in each ring Desmond J. Brown, Jonathan A. Ellman, Edward C. Taylor: The ... Chemistry of Heterocyclic Compounds, The Naphthyridines, John Wiley & Sons, 2007. ...
In a technical sense, it is a naphthyridone, not a quinolone: its ring structure is a 1,8-naphthyridine nucleus that contains ... Lesher GY, Froelich EJ, Gruett MD, Bailey JH, Brundage RP (September 1962). "1,8-Naphthyridine Derivatives. A New Class of ... Naphthyridines, WIN compounds, Carboxylic acids, Topoisomerase inhibitors). ...
It is isomeric with other naphthyridines including quinoxaline, cinnoline and quinazoline. Phthalazine can be obtained by the ...
It is isomeric with other naphthyridines including quinoxaline, phthalazine and quinazoline. The free base can be obtained as ...
It is isomeric with other naphthyridines including quinazoline, phthalazine and cinnoline. It is a colorless oil that melts ...
The organic ligands often pyridylamide, pyridone, naphthyridine, or their derivatives. Each metal atom is six-coordinate, ...
2009). "Anticancer and immunomodulatory activities of novel 1,8-naphthyridine derivatives". Journal of Enzyme Inhibition and ...
Li, Xiao-Ling; Xu, Min-Juan; Zhao, Yi-Lei; Xu, Jun (2010). "A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces ...
... naphthyridines as topoisomerase I inhibitors and potential anticancer agents". J. Med. Chem. 53 (24): 8716-26. doi:10.1021/ ...
DNA array is fabricated to test the G-G mismatch stabilizing properties of the naphthyridine dimer. Each of the four ... First G-G mismatch pair is stabilized by attaching it with the ligand, naphthyridine dimer, through hydrogen bonding which make ... the SPR difference image corresponding to the addition of sequence 2 in the presence of the naphthyridine dimer shows that, in ...
2004). "A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of ...
Reaction of 2-amino-7-chloro-1,8-naphthyridine with phthalic anhydride leads to the corresponding phthalimide. Selective ...
... naphthyridines Utilizing the Openshaw-Whittaker Hexahydrobenzo[a]quinolizinone Resolution". Heterocycles. 31 (2): 353. doi: ...
... such as an eight-membered ring introduced into the naphthyridine ring. Chemotherapy-induced emesis is a major problem in cancer ...
A novel chemical structure, "anisopusine"- a 1,7-naphthyridine alkaloid - was extracted from the dichloromethane soluble ...
"Discovery and Characterization of the Potent and Highly Selective 1,7-Naphthyridine-Based Inhibitors BAY-091 and BAY-297 of the ...
US patent 3590036, "Naphthyridine-3-carboxylic Acids, Their Derivatives and Preparation Thereof" Aceto MD, Botton I, Martin R, ...
... is a naphthyridine analog of the anticancer quinolone derivatives (AQDs), a class of compounds that has not been used ...
... and pazinaclone both contain an isoindolone structural motif Reaction of 2-Amino-7-chloro-1,8-naphthyridine with ... "2-Amino naphthyridine derivative, its preparation and its use", issued 12 March 1996, assigned to Rhone Poulenc Rorer SA. Atack ...
Niementowski . It included the development of synthesis of azaaromatic compounds: derivatives of pyridine, naphthyridine and ...
The first generation of the quinolones began following introduction of the related, but structurally distinct naphthyridine- ...
I. Synthesis and antibacterial activity of 7 beta-[D-2-[(4-hydroxy-1,5-naphthyridine-3-carbonylamino)- and (4-hydroxypyridine-3 ...
Naphthyridines, Ureas, All stub articles, Sedative stubs). ...
Naphthyridines, Piperazines, Sedatives, Dithianes, Nitrogen heterocycles, Sulfur heterocycles, Heterocyclic compounds with 2 ...
Other studies investigating the in vitro effects of several new synthetic compounds, including 2 naphthyridines, 2 ...
Naphthyridines, Carboxylic acids, All stub articles, Antibiotic stubs). ...
Among a large series of compounds built around a benzo[c]-[2,6]naphthyridine-8-carboxylic acid scaffold, CX-4945 was chosen for ... January 2011). "Discovery and SAR of 5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid (CX-4945), the first ... Naphthyridines, Orphan drugs, Protein kinase inhibitors, Carboxylic acids, Chloroarenes, All stub articles, Antineoplastic and ...