Nalbuphine
... has weak or no affinity for the sigma receptor(s) (e.g., Ki > 100,000 nM). Nalbuphine is said to be more morphine- ... Nalbuphine is available in two concentrations, 10 mg and 20 mg of nalbuphine hydrochloride per mL. Both strengths contain 0.94 ... Further research is therefore needed to compare nalbuphine with other postoperative opioids. Although nalbuphine possesses ... Nalbuphine binds with high affinity to the MOR and KOR, and has relatively low affinity for the DOR. It behaves as a moderate- ...
Agonist-antagonist
Schmidt WK, Tam SW, Shotzberger GS, Smith DH, Clark R, Vernier VG (February 1985). "Nalbuphine". Drug and Alcohol Dependence. ... nalbuphine, κ-agonist/μ-antagonist analgesic Agonist-antagonist opioids usually have a ceiling effect - over particular dose ...
Dinalbuphine sebacate
Whereas nalbuphine must be injected every 4 to 6 hours, a single injection of DNS lasts for up to 7 to 10 days. It was invented ... Nalbuphine, and hence DNS, acts as a mixed agonist/antagonist opioid modulator, or more specifically as a moderate-efficacy ... The compound is a diester of nalbuphine (Nubain) joined via a sebacic acid linker, and acts as a long-lasting prodrug of ... Huang PW, Liu HT, Hsiong CH, Pao LH, Lu CC, Ho ST, Hu OY (July 2013). "Simultaneous determination of nalbuphine and its prodrug ...
Analgesic
"Nubain (nalbuphine) dosing, indications, interactions, adverse effects, and more". Medscape Reference. WebMD. Archived from the ... Errick JK, Heel RC (September 1983). "Nalbuphine. A preliminary review of its pharmacological properties and therapeutic ...
Dextrorphan
"Dextrophan and Nalbuphine; Removal from Schedules" (PDF). NARA. Retrieved June 26, 2023. Zawertailo LA, Kaplan HL, Busto UE, ...
Pain management in children
A 2014 Cochrane Review for nalbuphine for postoperative pain treatment in children, reported insufficient evidence of the ... Schnabel, Alexander; Reichl, Sylvia U.; Zahn, Peter K.; Pogatzki-Zahn, Esther (2014-07-31). "Nalbuphine for postoperative pain ... efficacy and adverse events of nalbuphine in this population; further research is needed in this area. Other side effects of ...
Nalmexone
Nalbuphine Oxymorphone Naloxone Naltrexone Pentazocine Macdonald F (1997). Dictionary of Pharmacological Agents. CRC Press. p. ...
Butorphanol
Levallorphan Nalbuphine Nalfurafine Nalorphine Xorphanol Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes ... "The kappa opioid nalbuphine produces gender- and dose-dependent analgesia and antianalgesia in patients with postoperative pain ...
Nalorphine
Diacetylnalorphine Levallorphan Nalbuphine Nalorphine dinicotinate Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias ...
Local anesthetic
Greenbaum, R. A.; Kaye, G.; Mason, P. D. (July 1987). "Experience with nalbuphine, a new opioid analgesic, in acute myocardial ...
Nalodeine
Levallorphan Norcodeine Nalbuphine Buprenorphine Diprenorphine Samidorphan Gavril Pasternak (17 April 2013). The Opiate ...
Ketorfanol
Butorphanol Levallorphan Levomethorphan Levorphanol Nalbuphine Xorphanol Elks J (14 November 2014). The Dictionary of Drugs: ...
Levomethorphan
Butorphanol Cyclorphan Levallorphan Levorphanol Nalbuphine Oxilorphan Proxorphan Racemorphan Xorphanol Anvisa (2023-03-31). " ...
Cyclorphan
237 Butorphanol Levomethorphan Levorphanol Nalbuphine Oxilorphan Proxorphan Xorphanol Maxwell Gordon (2 December 2012). ...
Oxilorphan
Butorphanol Cyclorphan Ketorfanol Levallorphan Levomethorphan Levorphanol Nalbuphine Proxorphan Xorphanol Elks J (14 November ...
Proxorphan
Butorphanol Cyclorphan Ketorfanol Levallorphan Levomethorphan Levorphanol Moxazocine Nalbuphine Oxilorphan Xorphanol Elks J (14 ...
Buprenorphine
Freye E (1987). "Interaction of Mixed Agonist-Antagonists with Different Receptor Sites Using Nalbuphine as a Model Substance ...
Ceiling effect (pharmacology)
... such as nalbuphine, serve as a classic example of the ceiling effect; increasing the dose of a narcotic frequently leads to ...
Levallorphan
Butorphanol Cyclorphan Dextrallorphan Levomethorphan Levorphanol Nalbuphine Nalodeine Nalorphine Oxilorphan Proxorphan ...
Nalfurafine
Asimadoline Butorphanol Difelikefalin Nalbuphine Nalmefene Naltriben Noribogaine RB-64 Salvinorin A Nunley JR, Lerma EV (3 July ...
Κ-opioid receptor
It is thought that the hallucinogenic and dysphoric effects of opioids such as butorphanol, nalbuphine, and pentazocine serve ... Examples of KOR agonists that have been used medically as analgesics include butorphanol, nalbuphine, levorphanol, levallorphan ... alkaloid Nalbuphine - partial agonist Nalfurafine - full agonist, atypical agonist (possibly biased or subtype-selective) ...
Xorphanol
6-Methylenedihydrodesoxymorphine Butorphanol Cyclorphan Ketorfanol Levallorphan Levomethorphan Levorphanol Nalmefene Nalbuphine ...
Propiram
... nalbuphine, pentazocine, dezocine and its relatives. With about 10% of the analgesic potency of morphine, 50 mg of propiram is ...
Anesthetic
Methadone Morphine Nalbuphine Oxycodone, not available intravenously in U.S. Oxymorphone Pentazocine Muscle relaxants do not ...
Opioid antagonist
... nalbuphine, pentazocine, and phenazocine. All of the aforementioned drugs may be described as opioid modulators instead of as ...
Federal Correctional Institution, Fairton
An investigation revealed that from July 2008 to July 2009, Walters stole the drug nalbuphine hydrochloride, an opiate-based ...
Poppy straw
... nalbuphine, naloxone, naltrexone, buprenorphine, butorphanol and etorphine. PSC is an alternative to bricks of opium as an ...
Single Convention on Narcotic Drugs
... tramadol tapentadol nalbuphine (agonist-antagonist opioid) butorphanol (agonist-antagonist opioid) There are of course many ...
List of opioids
6-Keto Nalbuphine Aknadinine Butorphanol Cephakicine Cephasamine Cyprodime Drotebanol Fenfangjine G Ketorfanol Nalbuphine ...
Convention on Psychotropic Substances
... and a similar drug adrafinil nalbuphine (agonist-antagonist opioid) nicotine (stimulant) propofol and fospropofol (anesthetics ...