Muscarine
There are two mirror forms of muscarine, named: 2S-muscarine and 2R-muscarine. Figure 1. The structural formula of 2S-muscarine ... Muscarine, L-(+)-muscarine, or muscarin is a natural product found in certain mushrooms, particularly in Inocybe and Clitocybe ... Muscarine is readily soluble in water. The most likely way for muscarine to leave the blood is via renal clearance; it will ... Atropine is, like muscarine, an alkaloid but unlike muscarine is an antagonist of the muscarinic receptors. Hence, it inhibits ...
List of poisonous fungus species
Genest, K.; Hughes, D. W.; Rice, W. B. (1968-02-01). "Muscarine in Clitocybe species". Journal of Pharmaceutical Sciences. 57 ( ...
Inocybe
Many Inocybe species contain large doses of muscarine, and no easy method of distinguishing them from potentially edible ... Commonly the flesh contains muscarine. Originally placed in the family Cortinariaceae (later shown to be polyphyletic), ...
Oswald Schmiedeberg
In 1869 he demonstrated that muscarine had a similar effect on the heart as electrical stimulation of the vagus nerve. He also ... Das Muscarin. Das giftige Alkaloid des Fliegenpilzes (Agaricus muscarius L.) seine Darstellung, chemischen Eigenschaften, ... physiologischen Wirkungen, toxicologische Bedeutung und sein Verhältniss zur Pilzvergiftung im allgemeine, 1869 - Muscarine. ...
Arecoline
Chavibetol Muscarine "Poisons Standard October 2020". Federal Register of Legislation. The Australian Government. Ghelardini C ...
Inosperma maculatum
The mushroom is poisonous, containing muscarine compounds. Consumption of the mushroom could lead to a number of physiological ... Inosperma maculatum is poisonous, containing muscarine. Possible symptoms after consumption of I. maculatum mushrooms are ...
Inocybe geophylla
Like many fibrecaps, Inocybe geophylla contains muscarine. The symptoms are those of muscarine poisoning, namely, greatly ...
Clitocybe rivulosa
The main toxin in Clitocybe rivulosa is muscarine, and thus the symptoms are somewhat like that of nerve agent exposure, namely ... ISBN 0-7167-2649-1. Toxicity, Mushrooms - Muscarine (CS1 Latin-language sources (la), CS1 maint: location, CS1 French-language ... It contains potentially deadly levels of muscarine. A small whitish mushroom, the 3-4 cm diameter cap is funnel-shaped with ...
Clitocybe dealbata
The main toxic component of Clitocybe dealbata is muscarine, and thus the symptoms are like those of nerve agent poisoning, ... It contains potentially deadly levels of muscarine. Clitocybe dealbata was initially described by British naturalist James ... ISBN 0-7167-2649-1 Toxicity, Mushrooms - Muscarine (CS1: long volume value, CS1 maint: location, Articles with short ...
Adrenaline
Grossman M (1887). "Das muscarin-lungen-odem". Zeitschrift für klinische Medizin. 12: 550-591. Jackson DE (1912). "The ... system and the lungs was shown in 1887 when Grossman showed that stimulation of cardiac accelerator nerves reversed muscarine- ...
Inocybe whitei
It is considered poisonous as it contains muscarine. Similar species include Inocybe adaequata, Inocybe fraudans, and ...
Euphoria
Pilocarpine, arecoline and muscarine are rather selective parasympathetic agents; i.e., their cholinomimetic activity is ...
Clitocybe agrestis
Fruitbodies are poisonous as they contain the toxin muscarine. Harmaja H. (1969). "The genus Clitocybe (Agaricales) in ...
Inocybe rimosa
Its toxic ingredient is muscarine, discovered during the 1930s. Serious poisoning can result from consuming any quantity of the ...
Atropine
... or diphenhydramine can be used to treat muscarine intoxication.[medical citation needed] Atropine has been observed to ...
Clitocybe
Many small Clitocybe species contain the toxin muscarine, which was originally found in small amounts in the famous fly agaric ... A few members of the genus are considered edible; many others are poisonous, containing the toxin muscarine among others. ... However, the small white Clitocybe species contain muscarine in dangerous amounts, and two species in particular, the closely ... related Clitocybe dealbata and Clitocybe rivulosa, contain muscarine in such amounts that deaths have been recorded for eating ...
Muscarinic acetylcholine receptor M1
acetylcholine carbachol cevimeline muscarine oxotremorine pilocarpine vedaclidine xanomeline 77-LH-28-1 - brain penetrant ... Uchimura N, North RA (March 1990). "Muscarine reduces inwardly rectifying potassium conductance in rat nucleus accumbens ...
Muscarinic acetylcholine receptor
Inosperma erubescens
Inocybe erubescens contains a possibly fatal dose of the toxin muscarine. One fatality was recorded in Surrey in southern ... Toxicity, Mushrooms - Muscarine Wikimedia Commons has media related to Inocybe erubescens. (Articles with 'species' ...
Mushroom poisoning
Muscarine: Muscarine stimulates the muscarinic receptors of the nerves and muscles. Symptoms include sweating, salivation, ... Muscarine is found in mushrooms of the genus Omphalotus, notably the jack o' Lantern mushrooms. It is also found in A. muscaria ... Muscarine can also be found in some Inocybe species and Clitocybe species, in particular Clitocybe dealbata, and some red-pored ... Many Inocybe species such as Inocybe fastigiata and Inocybe geophylla contain muscarine Inosperma erubescens has caused death. ...
Pharmacophore
Kier LB (September 1967). "Molecular orbital calculation of preferred conformations of acetylcholine, muscarine, and muscarone ...
Alkaloid
260-263 Plemenkov, p. 242 Begley, Cofactor Biosynthesis John R. Lewis (2000). "Amaryllidaceae, muscarine, imidazole, oxazole, ...
Inocybe godeyi
The mushrooms are known to be poisonous, containing toxic compounds of muscarine. Consumption of the mushroom could lead to a ... I. godeyi is known to be poisonous, containing muscarine compounds, and consumption of the mushrooms can lead to SLUDGE ...
Inocybe praetervisa
It is inedible and probably poisonous due to the presence of muscarine. The ingestion of muscarine can lead to SLUDGE syndrome ... Mycologist Ian Robert Hall lists the mushroom as containing the poisonous compound muscarine. Consumption of muscarine could ...
Mycena pura
Given that it includes the toxin muscarine, it should not be consumed. Mycena pura does not appear to have any psychedelic ... The fungus also contains the mycotoxin muscarine, and the antifungal metabolite strobilurin D, the latter previously found in ...
History of catecholamine research
Electrical stimulation of the vagus nerve or injection of muscarine elicited peristalsis. This peristalsis was promptly ...
Inosperma bongardii
The fruit bodies are suspected to be toxic, as they contain muscarine. Fungi portal List of Inocybe species "GSD Species ...
Amanita muscaria
Muscarine, discovered in 1869, was long thought to be the active hallucinogenic agent in A. muscaria. Muscarine binds with ... The level of muscarine in A. muscaria is too low to play a role in the symptoms of poisoning. The major toxins involved in A. ... The levels of muscarine in Amanita muscaria are minute when compared with other poisonous fungi such as Inosperma erubescens, ... "The Hallucinogens Muscarine and Ibotenic Acid in the Middle Hindu Kush: A contribution on traditional medicinal mycology in ...
Chemical ecology
Similarly, the muscarinic acetylcholine receptor takes its name from the fungal toxin muscarine. In 1959, Adolf Butenandt ...
Acetylcholine receptor
The muscarine cholinergic receptor activates a G-protein when bound to extracellular ACh. The alpha subunit of the G-protein ... are particularly responsive to muscarine. Nicotinic and muscarinic are two main kinds of "cholinergic" receptors. Molecular ...