HMG-CoASqualaneLovastatinLanosterol 14 alpha-demethylase: ==Introduction==HMG-CoA reductase: HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-CoA reductase, officially abbreviated HMGCR) is the rate-controlling enzyme (NADH-dependent, ; NADPH-dependent, ) of the mevalonate pathway, the metabolic pathway that produces cholesterol and other isoprenoids. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor as well as oxidized species of cholesterol.Geranic acidPhenylpropanoic acidSterol carrier protein: A:437-540 A:437-540 A:628-731Undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase: Undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase (, PglC) is an enzyme with system name UDP-N,N'-diacetylbacillosamine:tritrans,heptacis-undecaprenyl-phosphate N,N'-diacetylbacillosamine transferase. This enzyme catalyses the following chemical reactionCholestyramineDolichol kinase deficiency: Dolichol kinase deficiency is a cutaneous condition caused by a mutation in the dolichol kinase gene.CholesterolLarix kaempferi: Larix kaempferi, known as Japanese larch or karamatsu (唐松) in Japanese) is a species of larch native to Japan, in the mountains of Chūbu and Kantō regions in central Honshū.Farjon, A.Thiosalicylic acidSteptoean positive carbon isotope excursion: The Steptoean Positive Carbon Isotope Excursion (SPICE) was a geological event which occurred about 500 million years ago at the end of the Cambrian Period. The SPICE event was a sudden reversal of the anoxia (lack of oxygen) that had steadily spread throughout the oceans during the Cambrian which also affected the atmosphere.Butyl acetate (disambiguation): Butyl acetate most often refers to n-butyl acetate. However, there are other isomers that may be considered to be butyl acetates:StatinPrenylation: Prenylation (also known as isoprenylation or lipidation) is the addition of hydrophobic molecules to a protein or chemical compound. It is usually assumed that prenyl groups (3-methyl-but-2-en-1-yl) facilitate attachment to cell membranes, similar to lipid anchors like the GPI anchor, though direct evidence is missing.Chromatographic response function: Chromatographic response function, often abbreviated to CRF, is a coefficient which measures the quality of the separation in the result of a chromatography.List of important publications in medicine: The definitive bibliographic source of books and articles demonstrating the history of medicine and identifying the first publications in the field is "Garrison and Morton". (Morton, Leslie T.RosuvastatinNADH:ubiquinone reductase (non-electrogenic): NADH:ubiquinone reductase (non-electrogenic) (, ubiquinone reductase, coenzyme Q reductase, dihydronicotinamide adenine dinucleotide-coenzyme Q reductase, DPNH-coenzyme Q reductase, DPNH-ubiquinone reductase, NADH-coenzyme Q oxidoreductase, NADH-coenzyme Q reductase, NADH-CoQ oxidoreductase, NADH-CoQ reductase) is an enzyme with system name NADH:ubiquinone oxidoreductase. This enzyme catalyses the following chemical reactionPravastatinTritium illumination: Tritium illumination is the use of gaseous tritium, a radioactive isotope of hydrogen, to create visible light. Tritium emits electrons through beta decay, and, when they interact with a phosphor material, fluorescent light is created, a process called radioluminescence.Dimethylallyl pyrophosphateOrange carotenoid N-terminal domain: In molecular biology the orange carotenoid N-terminal domain is a protein domain found predominantly at the N-terminus of the Orange carotenoid protein (OCP), and is involved in non-covalent binding of a carotenoid chromophore. It is unique for being present in soluble proteins, whereas the vast majority of domains capable of binding carotenoids are intrinsic membrane proteins.Phosphotransferase: Phosphotransferases are a category of enzymes (EC number 2.7) that catalyze phosphorylation reactions.Carbon-12: Carbon-12 is the more abundant carbon of the two stable isotopes, amounting to 98.93% of the element carbon; its abundance is due to the triple-alpha process by which it is created in stars.Mevalonate kinase deficiency: Mevalonate kinase deficiency, also called mevalonic aciduria, is an autosomal recessive metabolic disorder that disrupts the biosynthesis of cholesterol and isoprenoids.Pentane interference: Pentane interference or syn-pentane interaction is the steric hindrance that the two terminal methyl groups experience in one of the chemical conformations of n-pentane. The possible conformations are combinations of anti conformations and gauche conformations and are anti-anti, anti-gauche+, gauche+ - gauche+ and gauche+ - gauche− of which the last one is especially energetically unfavorable.Momilactone BDitrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific): Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific) (, RER2, Rer2p, Rer2p Z-prenyltransferase, Srt1p, Srt2p Z-prenyltransferase, ACPT, dehydrodolichyl diphosphate synthase 1) is an enzyme with system name (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 10--55 isopentenyl units). This enzyme catalyses the following chemical reactionElectron-capture mass spectrometry: Electron-capture mass spectrometry (EC-MS) is a type of mass spectrometry that uses electron capture ionization (ECI) to form negative ions from chemical compounds with positive electron affinities. The approach is particularly effective for electrophiles.Mycoplasma haemofelis: Mycoplasma haemofelis (formerly Haemobartonella felis) is a gram negative epierythrocytic parasitic bacterium. It often appears in bloodsmears as small (0.KIAA0895L: Uncharacterized protein KIAA0895-like also known as LOC653319, is a protein that in humans is encoded by the KIAA0895L gene.Liver sinusoid: A liver sinusoid is a type of sinusoidal blood vessel (with fenestrated, discontinuous endothelium) that serves as a location for the oxygen-rich blood from the hepatic artery and the nutrient-rich blood from the portal vein.SIU SOM Histology GIPhosphatidylinositol phosphate kinases: Phosphatidylinositol phosphate kinases (PIPK) are kinases that phosphorylate the phosphoinositides PtdInsP and PtdInsP2 that are derivatives of phosphatidylinositol (PtdIns). It has been found that PtdIns is only phosphorylated on three (3,4,5) of its five hydroxyl groups, possibly because D-2 and D-6 hydroxyl groups cannot be phosphorylated because of steric hindrance.