Methyl methanesulfonate
... Scorecard.org Accessed 14 Feb 08 Medical.Webends.com: Methyl Methanesulfonate Archived 2008-02-15 at ... Methyl methanesulfonate (MMS), also known as methyl mesylate, is an alkylating agent and a carcinogen. It is also a suspected ... "Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double-strand breaks". Nucleic ... Methyl esters, Methylating agents, Mesylate esters, Reagents for organic chemistry, IARC Group 2A carcinogens). ...
DNA repair and recombination protein RAD54-like
Mutants of hRAD54 are extremely sensitive to x-rays, as well as methyl methanesulfonate (MMS). These mutants are most likely ...
RAD51
"The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment". Proceedings of ...
Tetrahymena
Treatment with the DNA alkylating agent methyl methanesulfonate also resulted in substantially elevated Rad 51 protein levels. ...
Tetrahymena thermophila
Treatment with the DNA alkylating agent methyl methanesulfonate also resulted in substantially elevated Rad 51 protein levels. ...
Botryosphaeran
... and methyl methanesulfonate in Jurkat cells. Botryosphaeran exhibits hypoglycaemic activity (lowering of blood glucose levels) ... Botryosphaeran exhibited antigenotoxic activity against damage induced by methyl methanesulfonate, in normal and tumorigenic ( ...
Bloom syndrome
Human BLM cells are sensitive to DNA damaging agents such as UV and methyl methanesulfonate, indicating deficient repair ...
Gcn2
... radiation and exposure to methyl methanesulfonate (MMS). Thereby the cell prevents passing the G1 checkpoint and starting DNA ...
Ataxia telangiectasia and Rad3 related
... and methyl methanesulfonate. Deficiency of mei-41(ATR) also causes reduced spontaneous allelic recombination (crossing over) ...
RecQ helicase
Cells from humans with Bloom syndrome are sensitive to DNA damaging agents such as UV and methyl methanesulfonate indicating ...
POLD1
In the presence of DNA damage or replication stress (UV light, methyl methanesulfonate, hydroxyurea or aphidicolin), the POLD4/ ...
Colostrinin
Likewise, Colostrinin reduced the frequency of mutation caused by two mutagenic agents, methyl methane sulfonate and mitomycin- ...
Somatic recombination
MMS22L
Methyl methanesulfonate-sensitivity protein 22-like also known as MMS22-like, DNA repair protein is a protein that in humans is ...
Cajuína
... against methyl methanesulfonate, 4-nitroquinoline N-oxide and benzo[a]pyrene". Genetics and Molecular Biology. 31 (3): 759-766 ...
Saccharomyces cerevisiae
Herpes simplex virus
Enhanced survival of HSV-1 due to MR occurs upon exposure to different DNA damaging agents, including methyl methanesulfonate, ...
Almoxatone
... methyl]-2-oxazolidinone methanesulphonate (compound MD 780236) and the enzyme-catalysed oxidation of this compound as competing ...
Dimethyl sulfoxide
... a mutagenic alkylating compound Methyl methanesulfonate, another methylating agent Gloria Ramirez, also known as the "Toxic ... With methyl iodide it forms trimethylsulfoxonium iodide, [(CH3)3SO]I: (CH3)2SO + CH3I → [(CH3)3SO]I This salt can be ... N-methyl-2-pyrrolidone, and hexamethylphosphoramide (HMPA). DMSO is frequently used as a solvent for chemical reactions ... On the effect of nitric acid on methyl sulfide and ethyl sulfide]. In Erlenmeyer, E.; Rieckher, T.; Volhard, J.; Liebig, J.; ...
Dimethyl sulfite
SOCl2 + 2 CH3OH → (CH3O)2SO + 2 HCl Methyl methanesulfonate, a chemical with the same molecular formula but different ... this intermediate will exist only fleetingly in the presence of methanol and as such its decomposition to methyl chloride and ...
MMS
NASA Massachusetts Medical Society Methyl methanesulfonate Moment magnitude scale of earthquake energy Multiscale Modeling and ...
List of MeSH codes (D02)
... ethyl methanesulfonate MeSH D02.455.326.146.100.050.500.500 - methyl methanesulfonate MeSH D02.455.326.146.100.250 - hepes MeSH ... ethyl methanesulfonate MeSH D02.886.645.600.055.050.510.500 - methyl methanesulfonate MeSH D02.886.645.600.055.050.632 - sodium ... methyl methacrylates MeSH D02.241.081.069.800.550.450 - methyl methacrylate MeSH D02.241.081.069.800.550.500 - polymethyl ... methyl n-butyl ketone MeSH D02.522.585.175 - acetoacetates MeSH D02.522.585.342 - acetone MeSH D02.522.675.500 - methadyl ...
DNA ligase
T4 ligase mutants have increased sensitivity to both UV irradiation and the alkylating agent methyl methanesulfonate indicating ...
Adaptive response
It has been also demonstrated that alkB is required for reactivation of MMS-treated (methylating agent methyl methanesulfonate ... Ada protein can repair the damage by transferring methyl groups from O6-methylguanine or O4-methylthymine to Cys321 and also ... Sedgwick, B., Robins, P., Totty, Nick., Lindahl, Tomas.Functional Domains and Methyl Acceptor Sites of the Escherichia coli Ada ... which covalently transfers alkyl groups from the damaged DNA to one of its two active methyl acceptor cysteine residues: Cys69 ...
C2H6O3S
Methyl methanesulfonate This set index page lists chemical structure articles associated with the same molecular formula. If an ...
IARC group 2A
... inorganic Malathion 5-Methoxypsoralen Methyl methanesulfonate Mercaptobenzothiozole MNNG (N-Methyl-N'-nitro-N-nitrosoguanidine ... N-Methyl-N-nitrosourea Nitrate or nitrite (ingested) under conditions that result in endogenous nitrosation ortho-Nitroanisole ...
Mitotic recombination
Escherichia virus T4
Allopregnanolone
3α-hydroxy-3β-methyl-5α-pregnan-20-one), hydroxydione (21-hydroxy-5β-pregnane-3,20-dione), minaxolone (11α-(dimethylamino)-2β- ... 20-dioxo-5α-pregnan-21-yl methanesulfonate), and renanolone (3α-hydroxy-5β-pregnan-11,20-dione). The 21-hydroxylated derivative ... and the 3β-methyl analogue of allopregnanolone, ganaxolone, is under development to treat epilepsy and other conditions, ...
List of neurosteroids
2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1'-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation ... 20-dioxo-5α-pregnan-21-yl methanesulfonate - GABAA receptor positive allosteric modulator Posovolone (Co 134444): 3β-Hydroxy-21 ... 3β-methyl-5α-pregnan-3α-ol-20-one - GABAA receptor positive allosteric modulator Hydroxydione: 21-hydroxy-5β-pregnane-3,20- ... 3α-hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1'-yl)-19-nor-5β-pregnan-20-one - GABAA receptor positive allosteric modulator The ...