Mefloquine
Alcohol use should be avoided during treatment with mefloquine. Specifically it is used as mefloquine hydrochloride. Mefloquine ... Mefloquine is used to both prevent and treat certain forms of malaria. Mefloquine is useful for the prevention of malaria in ... "Lariam (Mefloquine) in the Armed Forces". Gofton TE, Al-Khotani A, O'Farrell B, Ang LC, McLachlan RS (April 2011). "Mefloquine ... Mefloquine was number 142,490 of a total of 250,000 antimalarial compounds screened during the study. Mefloquine was the first ...
Mepacrine
See mefloquine for more information. In addition to medical applications, mepacrine is an effective in vitro research tool for ... Chloroquine Amodiaquine Pamaquine Mefloquine "Quinacrine Shortage & What the ACR Is Doing about It". 13 March 2019 [8 February ... It is related to chloroquine and mefloquine. Although formerly available from compounding pharmacies, as of August 2020 it is ...
Kyle Brown (Canadian soldier)
An official inquiry in 1997 considered whether mefloquine, an anti-malarial drug that troops were taking, known to trigger ... ISBN 978-0770427559 "The mefloquine issue". Department of National Defence. 1997. Archived from the original on 2007-02-12. ...
Project 523
Arnold was among those who developed mefloquine in 1979 and was planning to test the new drug in China. He and his wife Moui ... Jiang, Jing-Bo; Guo, Xing-Bo; Li, Guo-Qiao; Cheung Kong, Yun; Arnold, Keith (1982). "Antimalarial activity of mefloquine and ... in which they reported the comparative efficacy of artemisinin and mefloquine on chloroquine-resistant Plasmodium falciparum. ...
Chloroquine
In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. The Centers ... and Mefloquine- may increase risk of convulsions. Chloroquine, in overdose, has a risk of death of about 20%. It is rapidly ...
Malaria
Artesunate plus mefloquine performs better than mefloquine alone in treating uncomplicated falciparum malaria in low ... Cochrane Infectious Diseases Group) (October 2005). "Artesunate plus mefloquine versus mefloquine for treating uncomplicated ... Doxycycline and the atovaquone/proguanil are better tolerated while mefloquine is taken once a week. Areas of the world with ... Mefloquine is more effective than sulfadoxine-pyrimethamine in preventing malaria for HIV-negative pregnant women. ...
Quinine
ISBN 978-1-59376-049-6. Stockwell JR (October 1982). "Aeromedical considerations of malaria prophylaxis with mefloquine ...
Malaria prophylaxis
Mefloquine is sometimes preferred due to its once a week dose, however mefloquine is not always as well tolerated when compared ... People who take mefloquine may be more likely to experience minor side effects such as sleep disturbances, depressed mood, and ... Mefloquine, doxycycline, and atovaquone-proguanil appear to be equally effective at reducing the risk of malaria for short-term ... Chloroquine, proguanil, mefloquine, and doxycycline are suppressive prophylactics. This means that they are only effective at ...
Progressive multifocal leukoencephalopathy
Gofton, T. E.; Al-Khotani, A.; O'Farrell, B.; Ang, L. C.; McLachlan, R. S. (June 2010). "Mefloquine in the treatment of ... the first case report appeared of a PML patient being successfully treated with the antimalarial drug mefloquine with activity ...
Roche
Lariam (mefloquine), for malaria (both prevention and treatment). Lexotanil (bromazepam), for anxiety disorders. Librax ( ...
Substance-induced psychosis
The related quinoline derivative mefloquine (Lariam) has also been associated with psychosis. some over-the-counter drugs, ... Encephalopathy and memory disorders during treatments with mefloquine]". Rev Méd Interne (in French). 14 (8): 788-91. doi: ...
Larium
A common misspelling of the drug name Lariam (Mefloquine). This disambiguation page lists articles associated with the title ...
Antimalarial medication
... of patients treated with mefloquine (in one hospital-based study). Mefloquine can only be taken for a period up to six months ... Mefloquine is effective in prophylaxis and for acute therapy. It is now used solely for the prevention of resistant strains of ... Mefloquine was developed during the Vietnam War and is chemically related to quinine. It was developed to protect American ... It is especially useful in areas where there is known to be a high level of resistance to chloroquine, mefloquine, and sulfa ...
Sanjeev Krishna
July 2004). "Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number". The Lancet. 364 (9432): 438 ... August 2006). "Decreasing pfmdr1 Copy Number in Plasmodium falciparum Malaria Heightens Susceptibility to Mefloquine, ...
INTERFET logistics
Subsequent trials of mefloquine in East Timor in 2001 and 2002 found that about 6.5 per cent of soldiers suffered side effects ... For those who suffered adverse side effects, a weekly dose of 250 milligrams (3.9 gr) of mefloquine was substituted. A terminal ... The falciparum cases were treated with a combination of quinine, mefloquine and doxycycline, while the vivax cases were treated ... Kitchener, Scott J.; Nasveld, Peter E.; Gregory, Robin M.; Edstein, Michael D. (21 February 2005). "Mefloquine and Doxycycline ...
Atovaquone
Malarone has fewer side effects and is more expensive than mefloquine. Resistance has been observed. For babesia, it is often ...
5-HT2A receptor
Mefloquine, an antimalarial drug, also produces psychiatric side effects which may be mediated through 5-HT2A and/or 5-HT2C ... July 2014). "Mefloquine and psychotomimetics share neurotransmitter receptor and transporter interactions in vitro". ...
WHO Model List of Essential Medicines
Artesunate/mefloquine (artesunate + mefloquine) Artesunate/pyronaridine tetraphosphate (artesunate + pyronaridine ... To be used in combination with either amodiaquine, mefloquine, or sulfadoxine + pyrimethamine. Other combinations that deliver ... Doxycycline Mefloquine Primaquine Quinine Sulfadoxine/pyrimethamine (sulfadoxine + pyrimethamine) Amodiaquine + sulfadoxine/ ... pyrimethamine (Co-packaged) Chloroquine Doxycycline Mefloquine Proguanil Sulfadoxine/pyrimethamine (sulfadoxine + pyrimethamine ...
WHO Model List of Essential Medicines for Children
Artesunate/mefloquine (artesunate + mefloquine) Artesunate/pyronaridine tetraphosphate (artesunate + pyronaridine ... To be used in combination with either amodiaquine, mefloquine or sulfadoxine + pyrimethamine. Other combinations that deliver ... Doxycycline Mefloquine Primaquine Quinine Sulfadoxine/pyrimethamine (sulfadoxine + pyrimethamine) Amodiaquine + sulfadoxine/ ... pyrimethamine (Co-packaged) Chloroquine Doxycycline Mefloquine Proguanil Sulfadoxine/pyrimethamine (sulfadoxine + pyrimethamine ...
COVID-19 drug repurposing research
Antiparasitics that have been investigated include chloroquine, hydroxychloroquine, mefloquine, ivermectin, and atovaquone. ...
Valproate
Mefloquine: may increase valproate metabolism combined with the direct epileptogenic effects of mefloquine. Oral contraceptives ...
Schistosomiasis
Mefloquine, which has previously been used to treat and prevent malaria, was recognised in 2008-2009 to be effective against ... Xiao SH (November 2013). "Mefloquine, a new type of compound against schistosomes and other helminthes in experimental studies ... Other possible treatments include a combination of praziquantel with metrifonate, artesunate, or mefloquine. A Cochrane review ...
Quinism
Neuropsychiatric quinism is a chronic encephalopathy due to intoxication by mefloquine, quinacrine, chloroquine. It is ... Chronic Encephalopathy Caused by Poisoning by Mefloquine and Related Quinoline Drugs". Veteran Psychiatry in the US. pp. 315- ... "Identification of a Syndrome Class of Neuropsychiatric Adverse Reactions to Mefloquine from Latent Class Modeling of FDA ...
Organofluorine chemistry
Examples include 5-fluorouracil, fluoxetine (Prozac), paroxetine (Paxil), ciprofloxacin (Cipro), mefloquine, and fluconazole. ... mefloquine, and fluconazole. Fluorine-substituted ethers are volatile anesthetics, including the commercial products ...
Plasmodium vivax
Mefloquine is a good alternative and in some countries is more readily available. Atovaquone-proguanil is an effective ... Maguire, J. D.; Marwoto, H.; Richie, T. L.; Fryauff, D. J.; Baird, J. K.; Baird, JK (15 April 2006). "Mefloquine Is Highly ...
Artesunate
Often it is used as part of combination therapy, such as artesunate plus mefloquine. It is not used for the prevention of ... There is moderate-quality evidence that treatment with artesunate plus mefloquine is superior to treatment with artesunate plus ... Peixoto HM, Marchesini PB, de Oliveira MR (November 2016). "Efficacy and safety of artesunate-mefloquine therapy for treating ...
Haloalkane
... mefloquine and fluconazole. Fluorine-substituted ethers are volatile anesthetics, including the commercial products ...
Fitness to dive
Mefloquine is seldom reported to have side-effects, but some people are allergic to it. Side effects include nausea, dizziness ... but the use of Mefloquine is not accepted by all diving medicine specialists. Antimalarial drug prophylaxis recommendations ...
Achalasia microcephaly
It was noted that only 5.4% of pregnancies under the medication of Mefloquine experienced abnormalities. This is the first case ... Unlike previous cases, the condition was attributed to the anti-malaria drug, Mefloquine, which was prescribed during pregnancy ...
IHCH-7113
AAZ-A-154 Efavirenz Lisuride Mefloquine NDTDI RH-34 SCHEMBL5334361 WAY-163909 Robichaud AJ, et al. Substituted heterocycle ...