... (EC 3.4.24.80, matrix metalloproteinase 14) is an enzyme. This enzyme catalyses the ... Membrane-type+matrix+metalloproteinase-1 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: ... Metalloproteinase Itoh Y, Takamura A, Ito N, Maru Y, Sato H, Suenaga N, Aoki T, Seiki M (September 2001). "Homophilic complex ...

"Entrez Gene: MMP16 matrix metallopeptidase 16 (membrane-inserted)". Nagase H, Woessner JF (1999). "Matrix metalloproteinases". ... Matrix metalloproteinase-16 is an enzyme that in humans is encoded by the MMP16 gene. Proteins of the matrix metalloproteinase ... Mattei MG, Roeckel N, Olsen BR, Apte SS (1997). "Genes of the membrane-type matrix metalloproteinase (MT-MMP) gene family, ... Jung M, Römer A, Keyszer G (2003). "mRNA expression of the five membrane-type matrix metalloproteinases MT1-MT5 in human ...

"Entrez Gene: MMP24 matrix metallopeptidase 24 (membrane-inserted)". Nagase H, Woessner JF (1999). "Matrix metalloproteinases". ... Matrix metalloproteinase-24 is an enzyme that in humans is encoded by the MMP24 gene. Proteins of the matrix metalloproteinase ... "Mint-3 regulates the retrieval of the internalized membrane-type matrix metalloproteinase, MT5-MMP, to the plasma membrane by ... 2008). "Expression of membrane-type 5 matrix metalloproteinase in human endometrium and endometriosis". Gynecol. Endocrinol. 23 ...

Seiki M (1999). "Membrane-type matrix metalloproteinases". APMIS. 107 (1): 137-143. doi:10.1111/j.1699-0463.1999.tb01536.x. ... Matrix metalloproteinases (MMP), which catalyse extracellular matrix degradation, have N-terminal domains that resemble PGBD. ... Yoshizaki T, Sato H, Furukawa M (2002). "Recent advances in the regulation of matrix metalloproteinase 2 activation: from basic ... "Analysis of the cell infiltrate and expression of proinflammatory cytokines and matrix metalloproteinases in arthroscopic ...

... activation of pro-matrix metalloproteinase-2 by leukolysin/membrane-type 6 matrix metalloproteinase/matrix metalloproteinase 25 ... Matrix metalloproteinase-25 is an enzyme that in humans is encoded by the MMP25 gene. Proteins of the matrix metalloproteinase ... 2000). "Membrane-type 6 matrix metalloproteinase (MT6-MMP, MMP-25) is the second glycosyl-phosphatidyl inositol (GPI)-anchored ... 1996). "The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and ...

"Testican 2 abrogates inhibition of membrane-type matrix metalloproteinases by other testican family proteins". Cancer Research ... are components of the extracellular matrix. SPOCK2 encodes a member of a novel Ca(2+)-binding proteoglycan family.[supplied by ...

"Claudin promotes activation of pro-matrix metalloproteinase-2 mediated by membrane-type matrix metalloproteinases". J. Biol. ... The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight ... Furuse M, Fujita K, Hiiragi T, Fujimoto K, Tsukita S (1998). "Claudin-1 and -2: novel integral membrane proteins localizing at ... is a member of an epithelial membrane protein superfamily". Gene. 226 (2): 285-95. doi:10.1016/S0378-1119(98)00553-8. PMID ...

"Claudin promotes activation of pro-matrix metalloproteinase-2 mediated by membrane-type matrix metalloproteinases". J. Biol. ... The protein encoded by this intron-less gene, a member of the claudin family, is an integral membrane protein and a component ... "Clostridium perfringens enterotoxin utilizes two structurally related membrane proteins as functional receptors in vivo". J. ...

Nakada M, Miyamori H, Yamashita J, Sato H (2003). "Testican 2 abrogates inhibition of membrane-type matrix metalloproteinases ...

It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Mutations in this ... Yana I, Weiss SJ (2000). "Regulation of Membrane Type-1 Matrix Metalloproteinase Activation by Proprotein Convertases". Mol. ...

Seiki M (2003). "Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion". Cancer Lett. 194 (1): 1-11. doi: ... Maskos K, Bode W (November 2003). "Structural basis of matrix metalloproteinases and tissue inhibitors of metalloproteinases". ... Okada Y, Hashimoto G (2001). "[Degradation of extracellular matrix by matrix metalloproteinases and joint destruction]". ... A specific region (183)RWTNNFREY(191) has been identified as a critical segment of matrix metalloproteinase 1 for the ...

Lafleur MA, Xu D, Hemler ME (April 2009). "Tetraspanin proteins regulate membrane type-1 matrix metalloproteinase-dependent ... Integral membrane proteins, All stub articles, Membrane protein stubs). ... Tetraspanin-12 is found in the membrane of a variety of cells. It has an unusually long C-terminal intracellular tail of ... a sheddase that interacts with a variety of adhesion molecules that are found on the cell membrane including L1-CAM, E-Cadherin ...

Matrix metalloproteinase-17 (MMP-17) also known as membrane-type matrix metalloproteinase 4 (MT-MMP 4) is an enzyme that in ... 2004). "Expression of membrane type-4 matrix metalloproteinase (metalloproteinase-17) by human eosinophils". Int. J. Biochem. ... 1999). "Human membrane type-4 matrix metalloproteinase (MT4-MMP) is encoded by a novel major transcript: isolation of ... 2000). "Membrane type 4 matrix metalloproteinase (MMP17) has tumor necrosis factor-alpha convertase activity but does not ...

Matrix metalloproteinase-19 (MMP-19) also known as matrix metalloproteinase RASI is an enzyme that in humans is encoded by the ... 1998). "Membrane-type 1 MMP (MMP-14) cleaves at three sites in the aggrecan interglobular domain". FEBS Lett. 430 (3): 186-90. ... Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal ... 2000). "Matrix metalloproteinases 19 and 20 cleave aggrecan and cartilage oligomeric matrix protein (COMP)". FEBS Lett. 478 (1- ...

1997). "Membrane-type matrix metalloproteinases 1 and 2 exhibit broad-spectrum proteolytic capacities comparable to many matrix ... Mattei MG, Roeckel N, Olsen BR, Apte SS (February 1997). "Genes of the membrane-type matrix metalloproteinase (MT-MMP) gene ... Takino T, Sato H, Shinagawa A, Seiki M (1995). "Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) ... 2003). "mRNA expression of the five membrane-type matrix metalloproteinases MT1-MT5 in human prostatic cell lines and their ...

Matrix metalloproteinases and NO present in inflamed tissue damage and degrade basal membrane, leading to development of IBD. ... Matrix metalloproteinases and cathepsins induced by inflammatory cytokines, together with RANKL, cause bone and cartilage ...

People with recalcitrant recurrent corneal erosions often show increased levels of matrix metalloproteinase (MMP) enzymes. ... Amniotic membrane tissue corneal bandages such as Prokera have been shown to be effective in alleviating RCE. These bandages ... "Treatment of recalcitrant recurrent corneal erosions with inhibitors of matrix metalloproteinase-9, doxycycline and ... It is thought that the natural regrowth of cells in the following days are better able to attach to the basement membrane to ...

Matrix metalloproteinases remove surrounding collagen, providing space for new blood vessels to grow. Craniotomy for unruptured ... The incision in the arachnoid membrane during the operation causes cerebrospinal fluid to leak into the subdural space, leading ... The resulting inflammation leads to new membrane formation through fibrosis and produces fragile and leaky blood vessels ...

MMPs are inhibited by tissue inhibitors of matrix metalloproteinases (TIMPs) which are found at lower levels in PPROM amniotic ... Breakdown of collagen: collagen is broken down by enzymes called matrix metalloproteinases (MMPs), which are found at higher ... Sealing membranes after rupture: Infection is the major risk associated with PROM and PPROM. By closing the ruptured membranes ... Prelabor rupture of membranes (PROM), previously known as premature rupture of membranes, is breakage of the amniotic sac ...

2005). "The membrane-anchored matrix metalloproteinase (MMP) regulator RECK in combination with MMP-9 serves as an informative ... 1998). "Regulation of matrix metalloproteinase-9 and inhibition of tumor invasion by the membrane-anchored glycoprotein RECK". ... In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key ... interacts with membrane type 1 matrix metalloproteinase and CD13/aminopeptidase N and modulates their endocytic pathways". J. ...

Hirano W, Gotoh I, Uekita T, Seiki M (Jun 2005). "Membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1 ( ... "Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the Cupin superfamily. A ...

"Collagen regulation of let-7 in pancreatic cancer involves TGF-β1-mediated membrane type 1-matrix metalloproteinase expression ...

... matrix metalloproteinases). There are at least eight human collagen receptors. Platelet membrane glycoproteins, mainly GPIa/IIa ... Collagen receptors are membrane proteins that bind the extracellular matrix protein collagen, the most abundant protein in ... Integrins function as the major cell receptor for extracellular matrix protein. These receptors comprise an α and β ... Receptor activation happens when collagen binds into preformed DDR dimers on cell membrane, when collagen is bound, a ...

Hydroxamates reduced the activity of ADAM17 and matrix metalloproteinases (MMPs), and attenuated expression of EMMPRIN, a tumor ... This resulted in less epithelial sloughing, improved protection of the basement membrane zone, and better epithelial-stromal ...

The ectodomain of the 44-kDa form of membrane type-1 matrix metalloproteinase does not modulate gelatinase A activation". J. ... membrane type 1-matrix metalloproteinase 1 (MT1-MMP)". J. Biol. Chem. 273 (2): 1216-22. doi:10.1074/jbc.273.2.1216. PMID ... "Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): Positive and negative regulators in tumor ... "Structural insight into the complex formation of latent matrix metalloproteinase 2 with tissue inhibitor of metalloproteinase 2 ...

The ectodomain of the 44-kDa form of membrane type-1 matrix metalloproteinase does not modulate gelatinase A activation". J. ... Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix (ECM) in normal ... "Structural insight into the complex formation of latent matrix metalloproteinase 2 with tissue inhibitor of metalloproteinase 2 ... "Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia ...

The activity of matrix metalloproteinases, specifically MMP-2 and MMP-9, are required for the penetration of the glia limitans ... This membrane lies deep to the pia mater and the subpial space and surrounds the perivascular spaces (Virchow-Robin spaces). ... These metalloproteinases allow immune cells to breach the glia limitans and reach the CNS parenchyma to attack the CNS ... This is most likely due to the biochemistry of the parenchymal basement membrane and the astrocytic foot processes. MMP-2 and ...

"Matrix metalloproteinases collagenase-2, macrophage elastase, collagenase-3, and membrane type 1-matrix metalloproteinase ... "Matrix metalloproteinase-13 predominates over matrix metalloproteinase-8 as the functional interstitial collagenase in mouse ... Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal ... Matrix Breakdown, Atherosclerosis, and Vascular Remodeling Through a Novel Pathway Involving MMP13 (Matrix Metalloproteinase 13 ...

2002). "The hemopexin-like C-terminal domain of membrane type 1 matrix metalloproteinase regulates proteolysis of a ... Jiang J, Zhang Y, Krainer AR, Xu RM (1999). "Crystal structure of human p32, a doughnut-shaped acidic mitochondrial matrix ... Jiang, Jianzhong (1999). "rystal structure of human p32, a doughnut-shaped acidic mitochondrial matrix protein". PNAS. 96 (7): ... Magallón-Tejada, Ariel (2016). "Cytoadhesion to gC1qR through Plasmodium falciparum Erythrocyte Membrane Protein 1 in Severe ...

... invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1- ... "Src-dependent phosphorylation of membrane type I matrix metalloproteinase on cytoplasmic tyrosine 573: role in endothelial and ... S1P or S1P analogs are likely to reach the binding pocket from within the cell membrane and not from the extracellular space, ...