MBInfo - Matrix metalloproteinases (MMPs) facilitate extracellular matrix disassembly The Matrix Metalloproteinase Protein ... Matrix metalloproteinases (MMPs), also known as matrix metallopeptidases or matrixins, are metalloproteinases that are calcium- ... "Cysteine array matrix metalloproteinase (CA-MMP)/MMP-23 is a type II transmembrane matrix metalloproteinase regulated by a ... a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase ...
Plant matrix metalloproteinases are metalloproteins and zinc enzymes found in plants. Matrix metalloproteinases (MMPs) are zinc ... Golldack, D., Popova, O., & Dietz, K. (2002). Mutation of the Matrix Metalloproteinase At2-MMP Inhibits Growth and Causes Late ... Golldack, D., Popova, O., & Dietz, K. (2002). Mutation of the Matrix Metalloproteinase At2-MMP Inhibits Growth and Causes Late ... In mammalian animals, extracellular matrix metalloproteinases (MMPs) modify the ECM to play significant roles in biological ...
... matrix metalloproteinase-23), a unique type of membrane-anchored matrix metalloproteinase and conditioned switching of its ... Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal ... Matrix metalloproteinase-23 is an enzyme that in humans is encoded by the MMP23B gene. This gene (MMP23B) encodes a member of ... Nagase H, Woessner JF (1999). "Matrix metalloproteinases". J. Biol. Chem. 274 (31): 21491-4. doi:10.1074/jbc.274.31.21491. PMID ...
Matrix metalloproteinase-16 is an enzyme that in humans is encoded by the MMP16 gene. Proteins of the matrix metalloproteinase ... "Entrez Gene: MMP16 matrix metallopeptidase 16 (membrane-inserted)". Nagase H, Woessner JF (1999). "Matrix metalloproteinases". ... Mattei MG, Roeckel N, Olsen BR, Apte SS (1997). "Genes of the membrane-type matrix metalloproteinase (MT-MMP) gene family, ... Jung M, Römer A, Keyszer G (2003). "mRNA expression of the five membrane-type matrix metalloproteinases MT1-MT5 in human ...
"Matrix metalloproteinases collagenase-2, macrophage elastase, collagenase-3, and membrane type 1-matrix metalloproteinase ... Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal ... "Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human optic nerve head astrocytes". Glia ... Matrix metalloproteinase-12 (MMP-12) also known as macrophage metalloelastase (MME) or macrophage elastase (ME) is an enzyme ...
"Matrix metalloproteinases collagenase-2, macrophage elastase, collagenase-3, and membrane type 1-matrix metalloproteinase ... Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal ... Matrix Breakdown, Atherosclerosis, and Vascular Remodeling Through a Novel Pathway Involving MMP13 (Matrix Metalloproteinase 13 ... It is a member of the matrix metalloproteinase (MMP) family. Like most MMPs, it is secreted as an inactive pro-form. MMP-13 has ...
Decreased expression of MMP-2 and MMP-3 matrix metalloproteinases, which are known to facilitate invasion and metastasis, ... Kessenbrock, K; Plaks, V; Werb, Z (2 April 2010). "Matrix metalloproteinases: regulators of the tumor microenvironment". Cell. ... 25 (13): 5363-79. doi:10.1128/MCB.25.13.5363-5379.2005. PMC 1156989. PMID 15964794. Shibata, A; Moiani, D; Arvai, AS; Perry, J ...
Matrix metalloproteinase 28, also known as epilysin, belongs to a family of proteins known as matrix metalloproteinases which ... Matrix metalloproteinases are commonly known to degrade the extracellular matrix, alongside regulating cell surface receptors ... June 2009). "Expression and function of matrix metalloproteinase (MMP)-28". Matrix Biology. 28 (5): 263-272. doi:10.1016/j. ... Matrix metalloproteinase 28 also known as epilysin is an enzyme that in humans is encoded by the MMP28 gene. ...
It contains a number of matrix metalloproteinase inhibitors. "Ferula persica Willd". Plants of the World Online. Royal Botanic ... Shahverdi, A.R.; Saadat, F.; Khorramizadeh, M.R.; Iranshahi, M.; Khoshayand, M.R. (2006). "Two matrix metalloproteinases ... 13 (9-10): 712-717. doi:10.1016/j.phymed.2006.01.003. PMID 16487689. v t e (Articles with short description, Short description ...
Murphy GJ, Murphy G, Reynolds JJ (September 1991). "The origin of matrix metalloproteinases and their familial relationships". ... Hz2V068 encodes a zinc-dependent matrix metalloprotease (ZnMc_MMP) and is most similar to Acyrthosiphon pisum MMP. This gene ... MMPs are important in cellular differentiation, morphogenesis, and pericellular proteolysis of the extracellular matrix and ... 94 (13): 6977-82. Bibcode:1997PNAS...94.6977W. doi:10.1073/pnas.94.13.6977. PMC 21270. PMID 9192677. Chen HQ, Chen KP, Yao Q, ...
Tetracyclines also have been found to inhibit matrix metalloproteinases. This mechanism does not add to their antibiotic ... Ryan ME, Usman A, Ramamurthy NS, Golub LM, Greenwald RA (February 2001). "Excessive matrix metalloproteinase activity in ... Retrieved 13 March 2017. Samuel D (1996). "Archaeology of ancient Egypt beer" (PDF). Journal of the American Society of Brewing ... Retrieved 13 March 2017. Chukwudi CU (August 2016). "rRNA Binding Sites and the Molecular Mechanism of Action of the ...
It is a potent pH buffer and has anti-matrix metalloproteinase activity, antioxidant and antiexcitotoxic properties and ... "Carnosine Protects against Cerebral Ischemic Injury by Inhibiting Matrix-Metalloproteinases". International Journal of ... Kim, EH; Kim, ES; Shin, D; Kim, D; Choi, S; Shin, YJ; Kim, KA; Noh, D; Caglayan, AB; Rajanikant, GK; Majid, A; Bae, ON (13 July ... 86 (13): 2984-91. doi:10.1002/jnr.21744. PMC 2805719. PMID 18543335. Rajanikant, GK; Zemke, D; Senut, MC; Frenkel, MB; Chen, AF ...
"The role of inflammation and matrix metalloproteinases in equine endometriosis". Journal of Veterinary Science. 13 (2): 171-177 ...
Hua, H.; Li, M.; Luo, T; Yin, Y.; Jiang, Y (2011). "Matrix Metalloproteinases in Tumorigenesis: an Evolving Paradigm". Cellular ... Metalloprotease inhibitors are cellular inhibitors of the Matrix metalloproteinases (MMPs). MMPs belong to a family of zinc- ... Brown, P. D. (1997). "Matrix metalloproteinase inhibitors in the treatment of cancer". Medical Oncology. 14 (1): 1-10. doi: ... Matrix metalloproteinase MMP inhibitors Collagen Cancer Periodontitis Arthritis Rheumatoid arthritis Osteoarthritis ...
Yuan W, Varga J (October 2001). "Transforming growth factor-beta repression of matrix metalloproteinase-1 in dermal fibroblasts ... Li Y, Li ZX, Jin T, Wang ZY, Zhao P (2017). "Tau Pathology Promotes the Reorganization of the Extracellular Matrix and Inhibits ... In the kidneys, TGF-B1 promotes accumulation of the extracellular matrix (ECM) by increasing its production and inhibiting its ... "Renal fibrosis is not reduced by blocking transforming growth factor-β signaling in matrix-producing interstitial cells". ...
Finally, many of these signaling processes can be regulated by matrix metalloproteinases (MMPs) as the targets of many MMPs are ... Ethell IM, Ethell DW (October 2007). "Matrix metalloproteinases in brain development and remodeling: synaptic functions and ... The hypothesized non-selective pathways indicate that the axons are guided to their destinations by the matrix through which ... or they may arise from changes activated in the extracellular matrix of the synaptic cleft. AChR experiences multimerization ...
February 2006). "Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix metalloproteinase (TIMP-1) in patients with ... A special role is played by Matrix metalloproteinases. These increase BBB T-cell permeability, specially in the case of MMP-9 ... Gray E, Thomas TL, Betmouni S, Scolding N, Love S (September 2008). "Elevated matrix metalloproteinase-9 and degradation of ... promoting inflammatory activity as well continued activation of proteins such as matrix metalloproteinases, which have ...
Jung JJ, Razavian M, Kim HY, Ye Y, Golestani R, Toczek J, Zhang J, Sadeghi MM (September 2016). "Matrix metalloproteinase ... Wehrli JM, Xia Y, Offenhammer B, Kleim B, Müller D, Bach DR (February 2023). "Effect of the Matrix Metalloproteinase Inhibitor ... Liu J, Xiong W, Baca-Regen L, Nagase H, Baxter BT (December 2003). "Mechanism of inhibition of matrix metalloproteinase-2 ... Liu J, Khalil RA (2017). "Matrix Metalloproteinase Inhibitors as Investigational and Therapeutic Tools in Unrestrained Tissue ...
People with recalcitrant recurrent corneal erosions often show increased levels of matrix metalloproteinase (MMP) enzymes. ... "Treatment of recalcitrant recurrent corneal erosions with inhibitors of matrix metalloproteinase-9, doxycycline and ... 132 (1): 8-13. doi:10.1016/S0002-9394(01)00913-8. PMID 11438047. Watson SL, Leung V (2018). "Interventions for recurrent ... 23 (7): 721-4. doi:10.3928/1081-597X-20070901-13. PMID 17912944. Huang, Yukan; Kheirkhah, Ahmad; Tseng, Scheffer C. G. (26 ...
"Functional analysis of the transcription factor ER71 and its activation of the matrix metalloproteinase-1 promoter". Nucleic ... 30 (13): 2972-9. doi:10.1093/nar/gkf390. PMC 117045. PMID 12087183. Imai Y, Nakada A, Hashida R, et al. (2002). "Cloning and ... 10 (5): 703-13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093. Buchberger A, Howard MJ, Proctor M, Bycroft M (2001). "The ...
Insights into the Role of Matrix Metalloproteinases in Precancerous Conditions and Colorectal Cancer;. Cancers (Basel). 2021 ... 2020 Winter;13(Suppl1):S47-S52. PMID 33585003; PMCID: PMC7881395. APC and AXIN2 Are Promising Biomarker Candidates for the ... Genes (Basel);. 2022 Apr 14;13(4):689. doi: 10.3390/genes13040689. PMID 35456495; PMCID: PMC9031605. ANRIL as a prognostic ...
Zhang C, Tang W, Li Y (2012-11-21). "Matrix metalloproteinase 13 (MMP13) is a direct target of osteoblast-specific ... causing the release of inflammatory cytokines and enhancing the breakdown of the bone matrix. In primary human cell cultures ... 13 (10): 2431-40. doi:10.1089/ten.2006.0406. PMC 2835465. PMID 17630878. Tu Q, Valverde P, Chen J (March 2006). "Osterix ...
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal ... Lee JM, Yin K, Hsin I, Chen S, Fryer JD, Holtzman DM, Hsu CY, Xu J (March 2005). "Matrix metalloproteinase-9 in cerebral- ... Li M, Yang G, Xie B, Babu K, Huang C (February 2014). "Changes in matrix metalloproteinase-9 levels during progression of ... Ramos-DeSimone N, Hahn-Dantona E, Sipley J, Nagase H, French DL, Quigley JP (May 1999). "Activation of matrix metalloproteinase ...
"Diffusion-weighted magnetic resonance imaging reversal by gene knockdown of matrix metalloproteinase-9 activities in live ... doi:10.1096/fj.13-234229. PMC 3868842. PMID 24115049. Liu CH, You Z, Liu CM, Kim YR, Whalen MJ, Rosen BR, Liu PK (March 2009 ... Retrieved 2017-01-13. Lefevre N, Naouri JF, Herman S, Gerometta A, Klouche S, Bohu Y (2016). "A Current Review of the Meniscus ... Retrieved 2017-10-13. Berger F, de Jonge M, Smithuis R, Maas M. "Stress fractures". Radiology Assistant. Radiology Society of ...
Hirano W, Gotoh I, Uekita T, Seiki M (Jun 2005). "Membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1 ( ... "Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the Cupin superfamily. A ...
... receptor-Ets protein interaction is a novel mechanism for steroid hormone-mediated down-modulation of matrix metalloproteinase ... 271 (39): 23907-13. doi:10.1074/jbc.271.39.23907. PMID 8798622. Wang ZY, Qiu QQ, Seufert W, Taguchi T, Testa JR, Whitmore SA, ... Mingot JM, Kostka S, Kraft R, Hartmann E, Görlich D (July 2001). "Importin 13: a novel mediator of nuclear import and export". ...
... via the inhibition of matrix metalloproteinase-2/-9 activity". Biochem. Biophys. Res. Commun. 330 (4): 1306-13. doi:10.1016/j. ... Alkaline hydrolysis 4.8 g sample tannin in 9 ml water are refluxed in 4.2 ml 40% NaOH for 6h at pH 12 - 13. Neutralization to ... Retrieved 2010-09-13. Pentagalloyl glucose on www.natural-specialities.com Archived 2010-10-12 at the Wayback Machine Haslam E ...
Ahn, G. O; Brown, J. M (2008). "Matrix Metalloproteinase-9 Is Required for Tumor Vasculogenesis but Not for Angiogenesis: Role ... Single-Agent Chemotherapy Induces Matrix Metalloproteinase-9 Expression and Accelerates Metastasis in Mice". Cancer Research. ... This effect is due to increased expression and activity of lysyl oxidase (LOX), an extracellular matrix remodeling enzyme ... Many of the growth factors, cytokines, extracellular matrix-modifying enzymes, and immune cells released during this process ...
In addition to producing VEGF-A, TAMs have been shown to modulate VEGF-A concentration through matrix metalloproteinase (MMP)-9 ... October 2000). "Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis". Nature Cell Biology. 2 (10): ... 6: 13. doi:10.12703/P6-13. PMC 3944738. PMID 24669294. Allavena P, Sica A, Solinas G, Porta C, Mantovani A (April 2008). "The ... doi:10.1158/0008-5472.CAN-13-2421. PMC 4137408. PMID 24638982. De Palma M, Venneri MA, Galli R, Sergi Sergi L, Politi LS, ...
Hsu, C. C.; Lai, S. C. (December 2007). "Matrix metalloproteinase-2, -9 and -13 are involved in fibronectin degradation of rat ... 13 (6 Pt 2): 896-901. doi:10.1161/01.hyp.13.6.896. PMID 2786848. S2CID 109606. Davis, Amy J. (January 1997). "The Heart of a ...