... is an enzyme which hydrolyses mannose. There are two types: alpha-Mannosidase beta-Mannosidase A deficiency is ... Mannosidases at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology v t e (EC 3.2.1, All stub ... A family of mannosidases are also responsible for processing newly formed glycoproteins in the endoplasmic reticulum into ...
... (EC 3.2.1.25}, mannanase, mannase, β-D-mannosidase, β-mannoside mannohydrolase, exo-β-D-mannanase, lysosomal β A ... "Entrez Gene: mannosidase". Chen H, Leipprandt JR, Traviss CE, Sopher BL, Jones MZ, Cavanagh KT, Friderici KH (February 1995). " ... 1994). "Human β-mannosidase deficiency associated with peripheral neuropathy". Ann. Neurol. 35 (1): 116-9. doi:10.1002/ana. ... 1998). "Human beta-mannosidase cDNA characterization and first identification of a mutation associated with human beta- ...
... α-D-mannosidase, p-nitrophenyl-α-mannosidase, α-D-mannopyranosidase, 1,2-α-mannosidase, 1,2-α-D-mannosidase, exo-α-mannosidase ... GeneReviews/NCBI/NIH/UW entry on Alpha-Mannosidosis OMIM entries on Alpha-Mannosidosis alpha-Mannosidase at the U.S. National ... Humans express the following three α-mannosidase isoenzymes: It can be utilized in experiments that determine the effects of ... Liberation of D-mannose from various glycoproteins by α-mannosidase isolated from jack bean meal". J. Biol. Chem. 241 (4): 1010 ...
... (EC 3.2.1.152, endo-beta-mannosidase) is an enzyme. This enzyme catalyses the ... Mannosylglycoprotein+endo-beta-mannosidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: ... Ishimizu T, Sasaki A, Okutani S, Maeda M, Yamagishi M, Hase S (September 2004). "Endo-beta-mannosidase, a plant enzyme acting ... "Partial purification and characterization of a novel endo-beta-mannosidase acting on N-linked sugar chains from Lilium ...
... may refer to: alpha-Mannosidase, an enzyme Mannosyl-oligosaccharide 1,2-alpha-mannosidase, an enzyme This ...
In enzymology, a 1,6-alpha-D-mannosidase (EC 3.2.1.163) is an enzyme that catalyzes the chemical reaction of separating the 1,6 ... purification and characterisation of two novel alpha-D-mannosidases from Aspergillus phoenicis". Carbohydr. Res. 340 (4): 609- ...
Mannosyl-oligosaccharide 1,2-α-mannosidase (EC 3.2.1.113, mannosidase 1A, mannosidase 1B, 1,2-α-mannosidase, exo-α-1,2- ... mannanase, mannose-9 processing α-mannosidase, glycoprotein processing mannosidase I, mannosidase I, Man9-mannosidase, ManI, 1, ... Tulsiani DR, Hubbard SC, Robbins PW, Touster O (April 1982). "α-D-Mannosidases of rat liver Golgi membranes: Mannosidase II is ... Kifunensine is a potent inhibitor of mannosidase I. Tabas I, Kornfeld S (November 1979). "Purification and characterization of ...
... (EC 3.2.1.78, endo-1,4-β-mannanase, endo-β-1,4-mannase, β-mannanase B, β-1, 4-mannan 4- ... Mannan+endo-1,4-beta-mannosidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology (EC ...
Glycoprotein endo-α-1,2-mannosidase (EC 3.2.1.130, glucosylmannosidase, endo-α-D-mannosidase, endo-α-mannosidase, ... MANEA Lubas WA, Spiro RG (March 1987). "Golgi endo-α-D-mannosidase from rat liver, a novel N-linked carbohydrate unit ... Glycoprotein+endo-alpha-1,2-mannosidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: ... glucosyl mannosidase)". Archives of Biochemistry and Biophysics. 277 (1): 114-21. doi:10.1016/0003-9861(90)90558-g. PMID ...
Mannan endo-1,6-α-mannosidase (EC 3.2.1.101, exo-1,6-β-mannanase, endo-α-1→6-D-mannanase, endo-1,6-β-mannanase, mannan endo-1,6 ... Mannan+endo-1,6-alpha-mannosidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology (EC ... mannosidase, 1,6-α-D-mannan mannanohydrolase) is an enzyme with systematic name 6-α-D-mannan mannanohydrolase. It catalyses the ...
... (EC 3.2.1.77, exo-1,2-1,3-α-mannosidase, 1,2-1,3-α-D-mannan mannohydrolase) is an enzyme with ... Mannan+1,2-(1,3)-alpha-mannosidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology (EC ... Mode of action of the Arthrobacter α-mannosidase on yeast mannan". The Journal of Biological Chemistry. 244 (3): 1052-9. PMID ... I. Purification and some properties of an α-mannosidase from an Arthrobacter species". The Journal of Biological Chemistry. 244 ...
... mannosidase II, exo-1,3-1,6-α-mannosidase, α-D-mannosidase II, α-mannosidase II, α-3,6-mannosidase, GlcNAc transferase I- ... dependent α1,3[α1,6]mannosidase, Golgi α-mannosidase II, ManII, 1,3(1,6)-α-D-mannosidase, 1,3-(1,6-)mannosyl-oligosaccharide α- ... Mannosidase II is the GlcNAcMAN5-cleaving enzyme in glycoprotein biosynthesis and mannosidases Ia and IB are the enzymes ... van den Elsen, J.M., Kuntz, D.A., Rose, D.R., "Structure of Golgi α-mannosidase II: a target for inhibition of growth and ...
... (EC 3.2.1.137, exo-1,2-1,6-alpha-mannosidase, 1,2-1,6-alpha-D-mannan D-mannohydrolase) is ... doi:10.1016/0304-4165(89)90069-x. Mannan+exo-1,2-1,6-alpha-mannosidase at the U.S. National Library of Medicine Medical Subject ... Takegawa K, Miki S, Jikibara T, Iwahara S (1989). "Purification and characterization of exo-α-D-mannosidase from a Cellulomonas ...
... beta-mannosidase (EC 3.2.1.25); myrosinase (EC 3.2.1.147). 6-phospho-beta-galactosidase InterPro: IPR005928 GBA3; KL; KLB; LCT ...
... CAZY GH_47 comprises enzymes with only one known activity; alpha-mannosidase (EC 3.2.1.113). ... Alpha-mannosidase is involved in the maturation of Asn-linked oligosaccharides. The enzyme hydrolyses terminal 1,2-linked alpha ... 2-mannosidase involved in the processing of asparagine-linked oligosaccharides". The Journal of Biological Chemistry. 269 (13 ...
... beta-mannosidase (EC 3.2.1.25); beta-glucuronidase (EC 3.2.1.31). These enzymes contain a conserved glutamic acid residue which ...
Inhibitors of B-Mannosidases?". Helv. Chim. Acta. 85 1118-. Cope, A.C.; Mehta, A.S. (1963). "Mechanism of the Hofmann ...
Beta-mannosidase "Mannosidosis, beta A, lysosomal , Genetic and Rare Diseases Information Center (GARD) - an NCATS Program". ... "OMIM Entry - * 609489 - MANNOSIDASE, BETA A, LYSOSOMAL; MANBA". www.omim.org. Retrieved 9 May 2018. Johnson, William (2015). ... The pathophysiology of this condition is better comprehended if one first looks at the normal function of beta-mannosidase, ... Beta-mannosidosis, also called lysosomal beta-mannosidase deficiency, is a disorder of oligosaccharide metabolism caused by ...
March 2001). "Mannosidase production by viridans group streptococci". J. Clin. Microbiol. 39 (3): 995-1001. doi:10.1128/JCM. ...
"Entrez Gene: MANEA mannosidase, endo-alpha". Land A, Braakman I (2001). "Folding of the human immunodeficiency virus type 1 ... Glycoprotein endo-alpha-1,2-mannosidase is an enzyme that in humans is encoded by the MANEA gene. GRCh38: Ensembl release 89: ... Spiro MJ, Bhoyroo VD, Spiro RG (1997). "Molecular cloning and expression of rat liver endo-alpha-mannosidase, an N-linked ...
4-beta-mannosidases. Mannan endo-1,4-beta-mannosidase hydrolyses mannan and galactomannan, but displays little activity towards ...
Stegelmeier BL, Ralphs MH, Gardner DR, Molyneux RJ, James LF (October 1994). "Serum alpha-mannosidase activity and the ... As the estimated intake of swainsonine increased, blood serum alpha-mannosidase activity and albumin decreased, and alkaline ... Swainsonine inhibits a lysosomal enzyme, alpha-mannosidase. This results in abnormal accumulation of the molecules normally ... and analyzing blood serum for alpha-mannosidase activity and swainsonine. In mule deer, clinical signs of locoism are similar ...
... glucosidases and mannosidases". J. Am. Chem. Soc. 65 (7): 1369-1380. doi:10.1021/ja01247a029. Liu Y, Zhou SH, Cheng YR, Chi Z, ...
The domain is predominantly found in the enzyme alpha-mannosidase. Henrissat B, Callebaut I, Fabrega S, Lehn P, Mornon JP, ... Glycoside hydrolase family 38 CAZY GH_38 comprises enzymes with only one known activity; alpha-mannosidase (EC 3.2.1.24) (EC ... "The structure of bovine lysosomal alpha-mannosidase suggests a novel mechanism for low-pH activation". Journal of Molecular ... 3.2.1.114). Lysosomal alpha-mannosidase is necessary for the catabolism of N-linked carbohydrates released during glycoprotein ...
... is a deficiency in mannosidase, an enzyme. There are two types: Alpha-mannosidosis and Beta-mannosidosis. ...
Hultberg B, Lundblad A, Masson PK, Ockerman PA (November 1975). "Specificity studies on alpha-mannosidases using ...
6-mannosidase EC 3.2.1.-, α-mannosidase EC 3.2.1.24, α-1,2-mannosidase EC 3.2.1.-, α-1,3-mannosidase EC 3.2.1.- and α-1,4- ... This domain occurs within alpha-1,2-mannosidases, which remove alpha-1,2-linked mannose residues from Man(9)(GlcNAc)(2) by ... Glycoside hydrolase family 92 includes enzymes with mannosyl-oligosaccharide α-1,2-mannosidase EC 3.2.1.113, mannosyl- ... mannosidase EC 3.2.1.- activities. It includes enzymes critical for the maturation of N-linked oligosaccharides and ER- ...
Mutations of the MAN2B1 gene result in the lack of production of the alpha-D-mannosidase enzyme or the production of a ... Alpha-mannosidosis is caused by genetic changes in the MAN2B1 gene, which codes for the lysosomal alpha-mannosidase enzyme. ... Velmanase alfa is a recombinant human lysosomal alpha-mannosidase. The most common adverse reactions include hypersensitivity ...
Epididymis-specific alpha-mannosidase precursor Mannosidase alpha class 2B member core-specific lysosomal alpha-1,6-Mannosidase ... "Entrez Gene: MAN2B2 mannosidase, alpha, class 2B, member 2". Land A, Braakman I (2001). "Folding of the human immunodeficiency ... Epididymis-specific alpha-mannosidase is an enzyme that in humans is encoded by the MAN2B2 gene. ... 1998). "Stage-specific expression of a mouse homologue of the porcine 135kDa alpha-D-mannosidase (MAN2B2) in type A ...
"Entrez Gene: MAN1B1 mannosidase, alpha, class 1B, member 1". Land A, Braakman I (2001). "Folding of the human immunodeficiency ... Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase is an enzyme that in humans is encoded by the MAN1B1 gene ... Tremblay LO, Herscovics A (Nov 1999). "Cloning and expression of a specific human alpha 1,2-mannosidase that trims Man9GlcNAc2 ... 2-mannosidase gene involved in N-glycan maturation". Glycobiology. 8 (6): 585-95. doi:10.1093/glycob/8.6.585. PMID 9592125. v t ...