Lipoprotein
... particles Lipoprotein(a) (LPA) is a lipoprotein particle of a certain phenotype High-density lipoproteins (HDL) collect fat ... The handling of lipoprotein particles in the body is referred to as lipoprotein particle metabolism. It is divided into two ... The links of mechanisms between different lipoprotein isoforms and risk for cardiovascular diseases, lipoprotein synthesis, ... Lipoproteins are larger and less dense when the fat to protein ratio is increased. They are classified on the basis of ...
Lipoprotein-X
... (Lp-X) is an abnormal low density lipoprotein found in cholestasis. Lipoprotein-X is a lamellar particle of 30 to ... The pathogenesis of lipoprotein-X in cholestasis is not totally resolved. Normally, the liver excretes lipoprotein complexes ... the formation of Lipoprotein-X in cholestasis. Lipoprotein-X is mainly removed by the reticuloendothelial system of the liver ... Using zonal ultracentrifugation, lipoprotein-X can be divided into three distinct populations: Lp-X1, Lp-X2, and Lp-X3, ...
Lipoprotein lipase
NIH/UW entry on Familial Lipoprotein Lipase Deficiency Gene therapy for lipoprotein lipase deficiency Lipoprotein+lipase at the ... "Entrez Gene: LPL lipoprotein lipase". Wang H, Eckel RH (2009). "Lipoprotein lipase: from gene to obesity". Am J Physiol ... Lipoprotein lipase (LPL) (EC 3.1.1.34, systematic name triacylglycerol acylhydrolase (lipoprotein-dependent)) is a member of ... Zechner R (1997). "The tissue-specific expression of lipoprotein lipase: implications for energy and lipoprotein metabolism". ...
Braun's lipoprotein
... (BLP, Lpp, murein lipoprotein, or major outer membrane lipoprotein), found in some gram-negative cell walls ... Large amounts of Braun's lipoprotein is present, more than any other protein in E. coli. Unlike other lipoproteins, it is ... Braun's lipoprotein binds to the pattern recognition receptor TLR2. Lpp induces adhesion of neutrophils to human endothelial ... The gene encoding Braun's lipoprotein initially produces a protein composed of 78 amino acids, which includes a 20 amino acid ...
Lipoprotein(a)
... is a low-density lipoprotein variant containing a protein called apolipoprotein(a). Genetic and epidemiological ... Lipoprotein Apolipoprotein Very-low-density lipoprotein Combined hyperlipidemia GRCh38: Ensembl release 89: ENSG00000198670 - ... Lipoprotein(a) [Lp(a)] consists of an LDL-like particle and the specific apolipoprotein(a), which is bound covalently to the ... Lipoprotein(a) - Lp(a) Desirable: 50 mg/dL (>125 nmol/L) Lp(a) appears with different isoforms (per kringle repeats) of ...
High-density lipoprotein
... (HDL) is one of the five major groups of lipoproteins. Lipoproteins are complex particles composed of ... Kwiterovich PO (Dec 2000). "The metabolic pathways of high-density lipoprotein, low-density lipoprotein, and triglycerides: a ... Unlike the larger lipoprotein particles, which deliver fat molecules to cells, HDL particles remove fat molecules from cells. ... With a size ranging from 5 to 17 nm, HDL is the smallest of the lipoprotein particles. It is the densest because it contains ...
Low-density lipoprotein
... very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), low-density lipoprotein (LDL) and high-density ... Low-density lipoprotein (LDL) is one of the five major groups of lipoprotein that transport all fat molecules around the body ... Lipoproteins transfer lipids (fats) around the body in the extracellular fluid, making fats available to body cells for ... Lipoproteins are complex particles composed of multiple proteins, typically 80-100 proteins per particle (organized by a single ...
Lipoprotein lipase deficiency
... is a genetic disorder in which a person has a defective gene for lipoprotein lipase, which leads ... More than 220 mutations in the LPL gene have been found to cause familial lipoprotein lipase deficiency so far.[citation needed ... "Familial lipoprotein lipase deficiency: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved 17 April 2019. Burnett, ... Familial lipoprotein lipase deficiency. Retrieved October 15, 2012. {{cite book}}: ,work= ignored (help) Gaudet, D; de Wal, J; ...
Intermediate-density lipoprotein
Intermediate-density lipoproteins (IDLs) belong to the lipoprotein particle family and are formed from the degradation of very ... low-density lipoproteins as well as high-density lipoproteins. IDL is one of the five major groups of lipoproteins ( ... The triglycerides in VLDL are removed in capillaries by the enzyme lipoprotein lipase, and the VLDL returns to the circulation ... refers to a density between that of high-density and low-density lipoproteins, it in fact refers to a density between that of ...
Lipolysis-stimulated lipoprotein receptor
... is a protein that in humans is encoded by the LSR gene. GRCh38: Ensembl release 89: ... "Entrez Gene: LSR lipolysis stimulated lipoprotein receptor". García JM, Peña C, García V, et al. (2008). "Prognostic value of ...
Lipoprotein-associated phospholipase A2
"The role of lipoprotein-associated phospholipase A2 in atherosclerosis may depend on its lipoprotein carrier in plasma". ... Lipoprotein-associated phospholipase A2 (Lp-PLA2) also known as platelet-activating factor acetylhydrolase (PAF-AH) is a ... May 2010). "Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative ... In the blood Lp-PLA2 travels mainly with low-density lipoprotein (LDL). Less than 20% is associated with high-density ...
Very low-density lipoprotein
... intermediate-density lipoprotein, low-density lipoprotein, high-density lipoprotein) that enable fats and cholesterol to move ... Very-low-density lipoprotein (VLDL), density relative to extracellular water, is a type of lipoprotein made by the liver. VLDL ... VLDL is converted in the bloodstream to low-density lipoprotein (LDL) and intermediate-density lipoprotein (IDL). VLDL ... "Proteome of human plasma very-low-density lipoprotein and low-density lipoprotein exhibits a link with coagulation and lipid ...
Lipoprotein receptor-related protein
... s, low density lipoprotein receptor-related proteins (HGNC) or prolow-density lipoprotein ... low density lipoprotein receptor-related protein associated protein 1) Lipoprotein receptor-related proteins are co-receptors ...
Low-density-lipoprotein receptor kinase
... low-density-lipoprotein] kinase, low-density lipoprotein kinase, low-density-lipoprotein receptor kinase (phosphorylating), and ... low-density-lipoprotein receptor]-L-serine]], whereas its two products are ADP and [[[low-density-lipoprotein receptor]-O- ... low-density-lipoprotein receptor]-L-serine O-phosphotransferase. Other names in common use include ATP:low-density-lipoprotein- ... low-density-lipoprotein receptor]-L-serine ⇌ {\displaystyle \rightleftharpoons } ADP + [low-density-lipoprotein receptor]-O- ...
Low-density lipoprotein receptor gene family
The low-density lipoprotein receptor gene family codes for a class of structurally related cell surface receptors that fulfill ... Li Y, Lu W, Marzolo MP, Bu G (May 2001). "Differential functions of members of the low density lipoprotein receptor family ... Beffert U, Stolt PC, Herz J (March 2004). "Functions of lipoprotein receptors in neurons". J. Lipid Res. 45 (3): 403-9. doi: ... Listed below are human proteins containing low-density lipoprotein receptor domains: C6; C7; 8A; 8B; C9; CD320; CFI; CORIN; ...
Low-density lipoprotein receptor-related protein 8
A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain". J Biol Chem. 271 ... Low-density lipoprotein receptor-related protein 8 (LRP8), also known as apolipoprotein E receptor 2 (ApoER2), is a protein ... Ma SL, Ng HK, Baum L, Pang JC, Chiu HF, Woo J, Tang NL, Lam LC (2003). "Low-density lipoprotein receptor-related protein 8 ( ... ApoER2 is a cell surface receptor that is part of the low-density lipoprotein receptor family. These receptors function in ...
Low-density lipoprotein receptor-related protein 4
... (LRP-4), also known as multiple epidermal growth factor-like domains 7 ( ... LRP-4 is a member of the Lipoprotein receptor-related protein family and may be a regulator of Wnt signaling. Mutations in this ... "Entrez Gene: low density lipoprotein receptor-related protein 4". Nakayama M, Nakajima D, Nagase T, Nomura N, Seki N, Ohara O ( ... "Molecular characterization and expression of the low-density lipoprotein receptor-related protein-10, a new member of the LDLR ...
Soluble low-density lipoprotein receptor-related protein
... (sLRP, LRP-515) is a biological substance naturally produced by the ... 1999). "Characterization of the soluble form of the low density lipoprotein receptor-related protein (LRP)". Exp. Cell Res. 251 ... 1997). "Soluble low density lipoprotein receptor-related protein (LRP) circulates in human plasma". J. Biol. Chem. 272 (38): ... 2007). "Clearance of amyloid-beta by circulating lipoprotein receptors". Nat. Med. 13 (9): 1029-1031. doi:10.1038/nm1635. PMC ...
Low-density lipoprotein receptor adapter protein 1
... is a protein that in humans is encoded by the LDLRAP1 gene. The protein ... "Entrez Gene: LDLRAP1 low density lipoprotein receptor adaptor protein 1". Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, ... 2004). "The modular adaptor protein ARH is required for low density lipoprotein (LDL) binding and internalization but not for ... 2006). "Adaptor protein ARH is recruited to the plasma membrane by low density lipoprotein (LDL) binding and modulates ...
Apheresis
LDL apheresis - removal of low density lipoprotein in patients with familial hypercholesterolemia. Lipoprotein(a) (Lp(a) ... "Lipoprotein (a)". CDC Office of Science (OS), Office of Genomics and Precision Public Health. U.S. Department of Health & Human ...
LDL receptor
The low-density lipoprotein receptor (LDL-R) is a mosaic protein of 839 amino acids (after removal of 21-amino acid signal ... "Low Density Lipoprotein Receptor". LOVD v.1.1.0 - Leiden Open Variation Database. Archived from the original on 2016-01-28. ... "LDLR low density lipoprotein receptor [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2016-10-10. ... "LDLR - Low-density lipoprotein receptor precursor - Homo sapiens (Human) - LDLR gene & protein". www.uniprot.org. Retrieved ...
List of OMIM disorder codes
ECM1 Lipoprotein glomerulopathy; 611771; APOE Lipoprotein lipase deficiency; 238600; LPL Lissencephaly 3; 611603; TUBA1A ...
Blood vessel disorder
Macrophages take up lipoprotein to form foam cells and release growth factor cytokines to attract more macrophages and smooth ... Lipoprotein level above > 25-30 mg/dl is considered more susceptible by blood vessel disorders. Some of the blood vessel ... A high-fat and high-cholesterol diet would result in an elevation of lipoprotein level, which is one of the constituents of ...
Paraoxonase
Because of their know association with high-density lipoprotein (HDL) and their effect on oxidized-LDL, PON1 and PON3 are ... Paraoxonase 1 also plays an important role as an antioxidant in preventing the oxidation of low-density lipoproteins (LDL), a ... "The Antioxidant Function of High Density Lipoproteins: A New Paradigm in Atherosclerosis." Revista Española De Cardiologia ... Parthasarathy S, Raghavamenon A, Garelnabi MO, Santanam N (2010). "Oxidized low-density lipoprotein". Free Radicals and ...
Alec Bangham
Horne, R. W.; Bangham, A. D.; Whittaker, V. P. (1963). "Negatively Stained Lipoprotein Membranes". Nature. 200 (4913): 1340. ...
Macromolecular assembly
Protein-lipid complexes: lipoprotein. The biomacromolecular complexes are studied structurally by X-ray crystallography, NMR ...
Liposome
Horne, R. W.; Bangham, A. D.; Whittaker, V. P. (1963). "Negatively Stained Lipoprotein Membranes". Nature. 200 (4913): 1340. ...
Chronic endothelial injury hypothesis
... making the lipoproteins water-soluble. Polyunsaturated fatty acids (PUFA) contained in the outer shell make the lipoproteins ... However, lipoproteins also contain antioxidants which protect the components, vitamin E and carotenoids being the two major ... ISBN 978-0-8493-2680-6. Bowry, V.W.; Ingold, K.U.; Stocker, R; R (1992). "Vitamin E in human low-density lipoprotein. When and ... Lipoproteins consist of a packaging of triglycerides and esterified cholesterol within a monolayer shell consisting of ...
Stefan D. Anker
Rauchhaus, M; Coats, AJ; Anker, SD (2000). "The endotoxin-lipoprotein hypothesis". Lancet. 356 (9233): 930-3. doi:10.1016/S0140 ...
Edward H. Kass
Sacks, Frank M.; Castelli, William P.; Donner, Allen; Kass, Edward H. (1975). "Plasma Lipids and Lipoproteins in Vegetarians ... "Plasma Lipoprotein Levels in Vegetarians". JAMA. 254 (10): 1337. doi:10.1001/jama.1985.03360100087019. Sacks, F. M.; Kass, E. H ...