Prolymphocytic leukemia
... is divided into two types according to the kind of cell involved: B-cell prolymphocytic leukemia and T- ... cell prolymphocytic leukemia. It is usually classified as a kind of chronic lymphocytic leukemia. Hsi, Eric D. (1 January 2012 ... v t e (Articles with short description, Short description is different from Wikidata, Lymphocytic leukemia, All stub articles, ... "12 - B-Cell Leukemias of Mature Lymphocytes". Hematopathology (Second ed.). W.B. Saunders. pp. 387-402. ISBN 978-1-4377-2606-0 ...
B-cell prolymphocytic leukemia
"Leukemia - B-cell Prolymphocytic Leukemia and Hairy Cell Leukemia: Treatment Options , Cancer.Net". Cancer.Net. 2012-06-25. ... It is a more aggressive, but still treatable, form of leukemia. Specifically, B-PLL is a prolymphocytic leukemia (PLL) that ... cite book}}: ,journal= ignored (help) "B-cell Prolymphocytic Leukemia (B-PLL) , Chronic Lymphocytic Leukemia". www.knowcancer. ... "Frequent deletions at 11q 23 and 13q14 in B cell prolymphocytic leukemia (B-PLL)". Leukemia. 14 (3): 427-30. doi:10.1038/sj.leu ...
T-cell prolymphocytic leukemia
... and T-prolymphocytic leukemia/T-cell lymphocytic leukemia. People affected by T-cell prolymphocytic leukemia typically have ... Most patients with T-cell prolymphocytic leukemia require immediate treatment. T-cell prolymphocytic leukemia is difficult to ... T-cell-prolymphocytic leukemia (T-PLL) is a mature T-cell leukemia with aggressive behavior and predilection for blood, bone ... "Inversions and tandem translocations involving chromosome 14q11 and 14q32 in T-prolymphocytic leukemia and T-cell leukemias in ...
Chronic lymphocytic leukemia
B cell prolymphocytic leukemia, and lymphoplasmacytic lymphoma. B cell prolymphocytic leukemia, a related, but more aggressive ... "France - Lymphoproliferative Syndrome B-Cell Prolymphocytic Leukemia ,". icgc.org. Retrieved 2016-11-18. "Hairy Cell Leukemia ... "T Cell Prolymphocytic Leukemia". AccessMedicine. Archived from the original on 2011-07-07. Retrieved 2009-02-04. Ascani S, ... However, these are now recognized as a separate disease group and are currently classified as T-cell prolymphocytic leukemias ( ...
Leukemia
T-cell prolymphocytic leukemia (T-PLL) is a very rare and aggressive leukemia affecting adults; somewhat more men than women ... Most people with T-cell prolymphocytic leukemia, a rare and aggressive leukemia with a median survival of less than one year, ... One subtype is B-cell prolymphocytic leukemia, a more aggressive disease. Acute myelogenous leukemia (AML) occurs far more ... Acute forms of leukemia are the most common forms of leukemia in children. Chronic leukemia is characterized by the excessive ...
Cancer immunotherapy
Dearden C (July 2012). "How I treat prolymphocytic leukemia". Blood. 120 (3): 538-51. doi:10.1182/blood-2012-01-380139. PMID ... peripheral T-cell lymphoma and T-cell prolymphocytic leukemia. CD52 is found on >95% of peripheral blood lymphocytes (both T- ... It is used in the treatment of chronic lymphocytic leukemia (CLL) because the cancerous cells of CLL are usually CD20- ... Castillo J, Perez K (2010). "The role of ofatumumab in the treatment of chronic lymphocytic leukemia resistant to previous ...
Prolymphocyte
Pluripotential hemopoietic stem cell Prolymphocytic leukemia "prolymphocytes in PLL". American Society of Hematology. 2013-07- ...
CD20
Tamayose K, Sato N, Ando J, Sugimoto K, Oshimi K (December 2002). "CD3-negative, CD20-positive T-cell prolymphocytic leukemia: ... It is found on B-cell lymphomas, hairy cell leukemia, B-cell chronic lymphocytic leukemia, and melanoma cancer stem cells. ... The anti-CD20 mAB ofatumumab (Genmab) was approved by FDA in October 2009 for chronic lymphocytic leukemia. The anti-CD20 mAB ... Leukemia. 17 (7): 1384-1389. doi:10.1038/sj.leu.2402978. PMID 12835728. Serke S, Schwaner I, Yordanova M, Szczepek A, Huhn D ( ...
Hairy cell leukemia
Similar to B-cell prolymphocytic leukemia (B-PLL) in chronic lymphocytic leukemia, HCL-V is a more aggressive disease. ... In 2013 the Hairy Cell Leukemia Foundation was created when the Hairy Cell Leukemia Consortium and the Hairy Cell Leukemia ... atypical chronic lymphocytic leukemia, B-cell prolymphocytic leukemia, or idiopathic myelofibrosis. When not further specified ... It is usually classified as a subtype of chronic lymphocytic leukemia (CLL). Hairy cell leukemia makes up about 2% of all ...
MTCP1
"A gene on chromosome Xq28 associated with T-cell prolymphocytic leukemia in two patients with ataxia telangiectasia". Leukemia ... in T-cell pro-lymphocytic leukaemia breaks within one gene and activates another". Oncogene. 8 (12): 3271-6. PMID 8247530. ... "The MTCP-1/c6.1B gene encodes for a cytoplasmic 8 kD protein overexpressed in T cell leukemia bearing a t(X;14) translocation ...
TCL1A
... an oncogene product involved in T-cell prolymphocytic leukemia, reveals a novel beta-barrel topology". Structure. 6 (2): 147-55 ... T-cell leukemia/lymphoma protein 1A is a protein that in humans is encoded by the TCL1A gene. TCL1A has been shown to interact ... Pekarsky Y, Hallas C, Croce CM (2001). "The role of TCL1 in human T-cell leukemia". Oncogene. 20 (40): 5638-43. doi:10.1038/sj. ... Kiss C, Nishikawa J, Takada K, Trivedi P, Klein G, Szekely L (2003). "T cell leukemia I oncogene expression depends on the ...
Fam158a
"Inversions and tandem translocations involving chromosome 14q11 and 14q32 in T-prolymphocytic leukemia and T-cell leukemias in ... T-Lymphocytic Leukemia with or without ataxia telangiectasia has been associated with inversions and tandem translocations of ...
RhoH
"Richter's and prolymphocytic transformation of chronic lymphocytic leukemia are associated with high mRNA expression of ... Leukemia. 21 (8): 1846-7. doi:10.1038/sj.leu.2404717. PMID 17443219. Traverse-Glehen A, Verney A, Baseggio L, Felman P, Callet- ... Leukemia. 21 (8): 1821-4. doi:10.1038/sj.leu.2404706. PMID 17476282. v t e (Articles with short description, Short description ... activation-induced cytidine deaminase and aberrant somatic hypermutation". Leukemia. 20 (6): 1089-95. doi:10.1038/sj.leu. ...
Leukemia cutis
... acute lymphoblastic leukemia, chronic lymphocytic leukemia, acute myeloid leukemia, and prolymphocytic leukemia. Granulocytic ... Leukemia cutis can occur in most forms of leukemia, including chronic myeloid leukemia, ... Leukemia cutis is the infiltration of neoplastic leukocytes or their precursors into the skin resulting in clinically ... This condition may be contrasted with leukemids, which are skin lesions that occur with leukemia, but which are not related to ...
Janus kinase 3
In addition, oncogenic JAK3 mutations have been identified in acute megakaryoblastic leukemia, T-cell prolymphocytic leukemia, ... JAK3 activating mutations are found in 16% of T-cell acute lymphoblastic leukemia (T-ALL) patients. ... and juvenile myelomonocytic leukemia and natural killer T-cell lymphoma (NK/T-lymphoma). Most mutations are located in the ... while activating Janus kinase 3 mutations lead to the development of leukemia. In addition to its well-known roles in T cells ...
TCL1 MTCP1 protein domain
These are overexpressed in T cell prolymphocytic leukemias as a result of chromosomal rearrangements that involve the ... They are, T-cell leukemia/lymphoma protein 1A TCL1A encoded by oncogene TCL-1 SWISSPROT and Protein p13 MTCP-1 encoded by MTCP- ...
Crystal Mackall
... to identify B-cell prolymphocytic leukemia and B-cell lymphoma. In 2022, Mackall was awarded $11.9 million from the California ... "FDA grants breakthrough therapy designation for new CAR T-cell therapy for B-cell acute lymphoblastic leukemia". National ... "Mackall awarded $11.9 million for anti-leukemia clinical trial". med.stanford.edu. 20 November 2017. Retrieved 2019-06-17. ... therapies for childhood leukemia and also developed a CAR targeting CD22 that is active in this disease and has received ...
Tower Cancer Research Foundation
Molecular allelokaryotyping of T-cell prolymphocytic leukemia cells with high density single nucleotide polymorphism arrays ...
Comparative genomic hybridization
... and also applied CGH to genomic DNA from patients affected with either Downs syndrome or T-cell prolymphocytic leukemia as well ... Array CGH is also frequently used in research and diagnostics of B cell malignancies, such as chronic lymphocytic leukemia. Cri ...
T-cell leukemia
Types include: Large granular lymphocytic leukemia Adult T-cell leukemia/lymphoma T-cell prolymphocytic leukemia In practice, ... T-cell leukemia describes several different types of lymphoid leukemia which affect T cells. ... Durer, Ceren; Babiker, Hani M. (2021). "Adult T Cell Leukemia". StatPearls. StatPearls Publishing. PMID 32644394. Retrieved 22 ... it can be hard to distinguish T-cell leukemia from T-cell lymphoma, and they are often grouped together. ...
International Classification of Diseases for Oncology
NOS M9832/3 Prolymphocytic leukemia, NOS M9833/3 B-cell prolymphocytic leukemia M9834/3 T-cell prolymphocytic leukemia M9835/3 ... NOS Blast cell leukemia Undifferentiated leukemia Stem cell leukemia M9805/3 Acute biphenotypic leukemia Acute leukemia of ... Leukemias M9860/3 Myeloid leukemia, NOS Non-lymphocytic leukemia, NOS Granulocytic leukemia, NOS Myelogenous leukemia, NOS ... leukemia Acute non-lymphocytic leukemia Acute granulocytic leukemia Acute myelogenous leukemia Acute myelocytic leukemia M9863/ ...
Index of oncology articles
... prolymphocytic leukemia - promegapoietin - promyelocytic leukemia - prophylactic cranial irradiation - prophylactic mastectomy ... acute lymphocytic leukemia - acute myelogenous leukemia - acute myeloid leukemia - acute nonlymphocytic leukemia - AD 32 - ... chronic leukemia - chronic lymphoblastic leukemia - chronic lymphocytic leukemia - chronic myelogenous leukemia - chronic ... myeloid leukemia - chronic myelomonocytic leukemia - chronic phase - chronic phase chronic myelogenous leukemia - CHS 828 - CI- ...
T(11:14)
... but also in B-cell prolymphocytic leukemia, in plasma cell leukemia, in splenic lymphoma with villous lymphocytes, in chronic ... lymphocytic leukemia, and in multiple myeloma. All these diseases involve B-lineage lymphocytes. In multiple myeloma, t(11;14) ...
List of diseases (P)
... familial Proliferating trichilemmal cyst Prolidase deficiency Prolymphocytic leukemia Properdin deficiency Prosencephaly ... arthritis Pavone-Fiumara-Rizzo syndrome Peanut hypersensitivity Pearson's marrow/pancreas syndrome Pediatric T-cell leukemia ... Phenylketonuric embryopathy Pheochromocytoma as part of NF Pheochromocytoma Philadelphia-negative chronic myeloid leukemia ...
Lymphoid leukemia
Other types include: Large granular lymphocytic leukemia Adult T-cell leukemia/lymphoma T-cell prolymphocytic leukemia In ... cell leukemia T-cell leukemia NK-cell leukemia The most common type of lymphoid leukemia is B-cell chronic lymphocytic leukemia ... B-cell prolymphocytic leukemia 9940/3 - Hairy cell leukemia T-cell leukemia describes several different types of lymphoid ... The most common T-cell leukemia is precursor T-cell lymphoblastic leukemia. It causes 15% of acute leukemias in childhood, and ...
Lymphoma
T-cell prolymphocytic leukemia T-cell large granular lymphocyte leukemia Aggressive NK cell leukemia Adult T-cell leukemia/ ... "Understanding Clinical Trials for Blood Cancers" (PDF). The Leukemia & Lymphoma Society. Leukemia and Lymphoma Society. ... indolent B-cell prolymphocytic leukemia Lymphoplasmacytic lymphoma (such as Waldenström macroglobulinemia) Splenic marginal ... "Chronic Leukemias". The Merck Manual of Geriatrics. Archived from the original on 2010-07-04. Lymphoma, Follicular at eMedicine ...
CKAP2
B-cell prolymphocytic leukemia, non-Hodgkin lymphoma, and in more than half cases of B-cell chronic lymphocytic leukemia. ...
B-cell leukemia
B-cell prolymphocytic leukemia 9835/3-9836/3 - Precursor B lymphoblastic leukemia 9940/3 - Hairy cell leukemia T-cell leukemia ... A B-cell leukemia is any of several types of lymphoid leukemia which affect B cells. Types include (with ICD-O code):[citation ... needed] 9823/3 - B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma 9826/3 - Acute lymphoblastic leukemia, mature B ... B-cell lymphoma "B-Cell Leukemia (Concept Id: C2004493) - MedGen - NCBI". www.ncbi.nlm.nih.gov. Retrieved 21 November 2021. ( ...
Hematologic disease
T-cell prolymphocytic leukemia (T-PLL) B-cell prolymphocytic leukemia (B-PLL) Chronic neutrophilic leukemia (CNL) Hairy cell ... Acute myelogenous leukemia (AML) Acute megakaryoblastic leukemia (AMKL), a sub-type of acute myelogenous leukemia Chronic ... leukemia (HCL) T-cell large granular lymphocyte leukemia (T-LGL) Aggressive NK-cell leukemia Hemochromatosis Asplenia ... Myelomas Multiple myeloma Waldenström macroglobulinemia Plasmacytoma Leukemias increased WBC Acute lymphocytic leukemia (ALL) ...
List of cancer types
T-cell lymphoma B-cell prolymphocytic leukemia Burkitt's lymphoma Chronic lymphocytic leukemia Chronic myelogenous leukemia ... leukemia Acute eosinophilic leukemia Acute lymphoblastic leukemia Acute myeloid leukemia Acute myeloid dendritic cell leukemia ... Lymphoma and leukemia: These two classes of cancer arise from immature cells that originate in the bone marrow, and are ... Acute lymphoblastic leukemia is the most common type of cancer in children, accounting for ~30% of cases. However, far more ...