Potassium channel opener: A potassium channel opener is a type of drug which facilitates ion transmission through potassium channels.Trans-tubular potassium gradient: The trans-tubular potassium gradient (TTKG) is an index reflecting the conservation of potassium in the cortical collecting ducts (CCD) of the kidneys. It is useful in diagnosing the causes of hyperkalemia or hypokalemia.Tertiapin: Tertiapin is a 21-amino acid peptide isolated from venom of the European honey bee (Apis mellifera). It blocks two different types of potassium channels, inward rectifier potassium channels (Kir) and calcium activated large conductance potassium channels (BK).Potassium channel blocker: Potassium channel blockers are agents which interfere with conduction through potassium channels.Voltage-gated potassium channel database: VKCDB (Voltage-gated potassium Channel DataBase) is a database of functional data about the voltage-gated potassium channels.Margatoxin: Margatoxin (MgTX) is a peptide that selectively inhibits Kv1.3 voltage-dependent potassium channels.Stretch-activated ion channel: Stretch-activated or stretch-gated ion channels are ion channels which open their pores in response to mechanical deformation of a neuron's plasma membrane. Also see mechanosensitive ion channels and mechanosensitive channels, with which they may be synonymous.Jacob Shaw (comics): Jacob Shaw is a fictional character in Marvel Comics, created by Ben Raab and Charlie Adlard. He is the father of Sebastian Shaw (the Black King of the Hellfire Club and enemy of the X-Men).Calcium-activated potassium channel: Calcium-activated potassium channels are potassium channels gated by calcium, or are structurally or phylogenetically related to calcium gated channels. In humans they are divided into BK channels, IK channels, and SK channels based on their conductance (big, intermediate, and small conductance).Voltage-dependent calcium channel: Voltage-dependent calcium channels (VDCC) are a group of voltage-gated ion channels found in the membrane of excitable cells (e.g.E-4031: E-4031 is an experimental class III antiarrhythmic drug that blocks potassium channels of the hERG-type.Kim I, Boyle KM, Carrol JL (2005) Postnatal development of E-4031-sensitive potassium current in rat carotid chemoreceptor cells.KCNB2: Potassium voltage-gated channel subfamily B member 2 is a protein that in humans is encoded by the KCNB2 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.Ankyrin-G binding motif of KCNQ2-3: In molecular biology, the ankyrin-G binding motif of KCNQ2-3 is a protein motif found in the potassium channels KCNQ2 and KCNQ3.Cardiac transient outward potassium currentList of MeSH codes (D12.776.543): This is a sub-part (membrane proteins only) of List of MeSH codes (D12.776), itself a part of the list of the "D" codes for MeSH.Tandem pore domain potassium channel: The two-pore-domain potassium channel (not to be confused with the small family of two-pore channels) a family of 15 members form what is known as "leak channels" which possess Goldman-Hodgkin-Katz (open) rectification. These channels are regulated by several mechanisms including oxygen tension, pH, mechanical stretch, and G-proteins .Reversal potential: In a biological membrane, the reversal potential (also known as the Nernst potential) of an ion is the membrane potential at which there is no net (overall) flow of that particular ion from one side of the membrane to the other. In the case of post-synaptic neurons, the reversal potential is the membrane potential at which a given neurotransmitter causes no net current flow of ions through that neurotransmitter receptor's ion channel.XEN-D0101: XEN-D0101 is a drug that was developed to treat atrial fibrillation. Xention, a biopharmaceutical company based in Cambridge, United Kingdom, created XEN-D0101 along with other ion channel-modulating drugs.ATC code C08: ==C08C Selective calcium channel blockers with mainly vascular effects==Patch clamp: The patch clamp technique is a laboratory technique in electrophysiology that allows the study of single or multiple ion channels in cells. The technique can be applied to a wide variety of cells, but is especially useful in the study of excitable cells such as neurons, cardiomyocytes, muscle fibers, and pancreatic beta cells.Periodic current reversalG protein-gated ion channelSK channel: SK channels (Small conductance calcium-activated potassium channels) are a subfamily of Ca2+-activated K+ channels. They are so called because of their small single channel conductance in the order of 10 pS.Chloride channel: C:88-438, A:88-438, B:88-438, F:88-438, A:88-438, B:88-438, B:88-438, A:88-438, B:88-438, B:88-438, B:88-438Tetraethylammonium chlorideElectrical conductivity meterOocyte selection: Oocyte selection is a procedure that is performed prior to in vitro fertilization, in order to use oocytes with maximal chances of resulting in pregnancy. In contrast, embryo selection takes place after fertilization.Ablomin: Ablomin is a toxin present in the venom of the Japanese Mamushi snake, which blocks L-type voltage-gated calcium channels.Neuronal calcium sensor: Neuronal Calcium Sensor is a large family of proteins which work as calcium dependent molecular switches and includes members like Frequenin (NCS1), recoverin, GCAP, neurocalcin, visinin etc. All the members carry 4 EF hand motifs (out of which only 2 or 3 bind calcium) and an N-myristoyl group.Scyllatoxin: Scyllatoxin (also leiurotoxin I) is a toxin, from the scorpion Leiurus quinquestriatus hebraeus, which blocks small-conductance Ca2+-activated K+ channels.CromakalimVentricular action potentialColes PhillipsProtein primary structure: The primary structure of a peptide or protein is the linear sequence of its amino acid structural units, and partly comprises its overall biomolecular structure. By convention, the primary structure of a protein is reported starting from the amino-terminal (N) end to the carboxyl-terminal (C) end.Fractional sodium excretion: The fractional excretion of sodium (FENa) is the percentage of the sodium filtered by the kidney which is excreted in the urine. It is measured in terms of plasma and urine sodium, rather than by the interpretation of urinary sodium concentration alone, as urinary sodium concentrations can vary with water reabsorption.Omega-grammotoxin SIA: Omega-grammotoxin SIA is a protein toxin that inhibits P, Q and N voltage-gated calcium channels (Ca2+ channels) in neurons.Inhibitor protein: The inhibitor protein (IP) is situated in the mitochondrial matrix and protects the cell against rapid ATP hydrolysis during momentary ischaemia. In oxygen absence, the pH of the matrix drops.Calcium signaling: Calcium ions are important for cellular signalling, as once they enter the cytosol of the cytoplasm they exert allosteric regulatory effects on many enzymes and proteins. Calcium can act in signal transduction resulting from activation of ion channels or as a second messenger caused by indirect signal transduction pathways such as G protein-coupled receptors.Burst kinetics: Burst kinetics is a form of enzyme kinetics that refers to an initial high velocity of enzymatic turnover when adding enzyme to substrate. This initial period of high velocity product formation is referred to as the "Burst Phase".Barium orthotitanate: Barium orthotitanate is the inorganic compound with the chemical formula Ba2TiO4. It is a colourless solid that is of interest because of its relationship to barium titanate, a useful electroceramic.Potassium deficiency (plants): ==Soil type and potassium deficiency==HSD2 neurons: HSD2 neurons are a small group of neurons in the brainstem which are uniquely sensitive to the mineralocorticosteroid hormone aldosterone, through expression of HSD11B2. They are located within the caudal medulla oblongata, in the nucleus of the solitary tract (NTS).Ion channelPotassium hydrogenacetylenedicarboxylate: Potassium hydrogenacetylenedicarboxylate is a potassium salt with chemical formula KC4HO4 or K+·HC4O4−, often abbreviated as KHadc. It is often called potassium hydrogen acetylenedicarboxylate or monopotassium acetylenedicarboxylate.TRPC: TRPC is a family of transient receptor potential cation channels in animals.Concentration effect: In the study of inhaled anesthetics, the concentration effect is the increase in the rate that the Fa(alveolar concentration)/Fi(inspired concentration) ratio rises as the alveolar concentration of that gas is increased. In simple terms, the higher the concentration of gas administered, the faster the alveolar concentration of that gas approaches the inspired concentration.BenzopyranAcanthophis: Acanthophis is a genus of elapid snakes. Commonly called death adders, they are native to Australia, New Guinea and nearby islands, and are among the most venomous snakes in the world.Cell membraneCalcium-activated potassium channel beta subunit: In molecular biology, the calcium-activated potassium channel beta subunit is a family of proteins comprising the beta subunits of calcium-activated potassium channels.Bay K8644Molecular modificationCaesium bromideSilent mutation: Silent mutations are mutations in DNA that do not significantly alter the phenotype of the organism in which they occur. Silent mutations can occur in non-coding regions (outside of genes or within introns), or they may occur within exons.FERM domain: In molecular biology, the FERM domain (F for 4.1 protein, E for ezrin, R for radixin and M for moesin) is a widespread protein module involved in localising proteins to the plasma membrane.RetigabineAcid-sensing ion channel: Acid-Sensing Ion Channels (ASICs) are neuronal voltage-insensitive cationic channels activated by extracellular protons. ASIC proteins are a subfamily of the ENaC/Deg superfamily of ion channels.DiazoxideTRPV1: The transient receptor potential cation channel subfamily V member 1 (TrpV1), also known as the capsaicin receptor and the vanilloid receptor 1, is a protein that, in humans, is encoded by the TRPV1 gene. It was the first isolated member of the transient receptor potential vanilloid receptor proteins that in turn are a sub-family of the transient receptor potential protein group.DaptomycinTRPM: TRPM is a family of transient receptor potential ion channels (the "M" stands for "melastatin"). Functional TRPM channels are believed to form tetramers.Reaction coordinateRubidium standard: A rubidium standard or rubidium atomic clock is a frequency standard in which a specified hyperfine transition of electrons in rubidium-87 atoms is used to control the output frequency. It is the most inexpensive, compact, and widely used type of atomic clock, used to control the frequency of television stations, cell phone base stations, in test equipment, and global navigation satellite systems like GPS.
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