In cell biology, a lymphokine-activated killer cell (also known as a LAK cell) is a white blood cell that has been stimulated ... Lymphokine-Activated+Killer+Cells at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Cell biology ... The mechanism of LAK cells is distinctive from that of natural killer cells because they can lyse cells that NK cells cannot. ... "Cannabinoids increase lung cancer cell lysis by lymphokine-activated killer cells via upregulation of ICAM-1". Biochemical ...
Dummer, R.; Schäfer, E.; Eilles, C.; Börner, W.; Burg, G., (1991). Lymphokine-activated killer-cell traffic in metastatic ... and Hodgkin cell specific antigen on atypical cells in lymphomatoid papulosis. 2nd Internat. Conference on Malignant Lymphoma. ... A.; Wiede, J. (1991). A Subcutaneous Delta-Positive T-Cell Lymphoma That Produces Interferon Gamma. N. Engl J Med 325:1078-1081 ... Then, pattern-diagnostic of lymphoproliferative skin infiltrates (T- and B-cell pattern), and Characterization of CD 30- ...
Natural killer cell Natural killer T cell Lymphokine-activated killer cell Interleukin Cancer immunotherapy Schmidt-Wolf, IG; ... CIK cells is distinctive from that of natural killer cells or LAK cells because they can lyse cells that NK cells and LAK cells ... Cytokine-induced killer cells (CIK) cells are a group of immune effector cells featuring a mixed T- and natural killer (NK) ... CIK cells have, as a key feature, a double T-cell and NK cell-like phenotype. This unique combination of T-cell and NK-cell ...
It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell ... The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions ... Inohara H, Akahani S, Koths K, Raz A (1996). "Interactions between galectin-3 and Mac-2-binding protein mediate cell-cell ... Cell. Proteomics. 3 (7): 715-28. doi:10.1074/mcp.M400015-MCP200. PMID 15084671. v t e (Articles with short description, Short ...
... lymphokine-activated killer T-cell-originated protein kinase, specifically expressed in the testis and activated lymphoid cells ... Lymphokine-activated killer T-cell-originated protein kinase is an enzyme that in humans is encoded by the PBK gene. The ... 2007). "T-lymphokine-activated killer cell-originated protein kinase functions as a positive regulator of c-Jun-NH2-kinase 1 ... Overview of all the structural information available in the PDB for UniProt: Q96KB5 (Lymphokine-activated killer T-cell- ...
Cell types that can be used in this way are natural killer (NK) cells, lymphokine-activated killer cells, cytotoxic T cells and ... The activated T cells interact with the viruses to become CAR T cells. The interleukins stimulate these CAR T cells to ... In normal physiology T-cells are activated by two signals: the T-cell receptor binding to an antigen-MHC complex and T-cell ... Fc receptors are found on many immune system cells, including NK cells. When NK cells encounter antibody-coated cells, the ...
This may be because VAP-1 is involved in binding TIL, lymphokine-activated killer cells, and natural killer cells to the ... Bustelo XR, Barbacid M (May 1992). "Tyrosine phosphorylation of the vav proto-oncogene product in activated B cells". Science. ... Cell processes involved in insulin resistance are often associated with elevated VAP-1 expression and modified GLUT expression ... Solé M, Unzeta M (Nov 2011). "Vascular cell lines expressing SSAO/VAP-1: a new experimental tool to study its involvement in ...
... of the human granzyme H gene directs expression to T/natural killer cell progenitors and lymphokine-activated killer cells in ... "Natural killer cell-derived human granzyme H induces an alternative, caspase-independent cell-death program". Blood. 110 (2): ... Edwards KM, Kam CM, Powers JC, Trapani JA (1999). "The human cytotoxic T cell granule serine protease granzyme H has ... Johnson H, Scorrano L, Korsmeyer SJ, Ley TJ (2003). "Cell death induced by granzyme C". Blood. 101 (8): 3093-101. doi:10.1182/ ...
... that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells". Proc Natl Acad Sci USA 1994, 91( ... stimulates T-cell proliferation and the induction of lymphokine-activated killer cells". Proc Natl Acad Sci USA 1994, 91(11): ... "Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells and cytokine production during first-in- ... "Immunoglobulin gene rearrangement and cell surface antigen expression of acute lymphocyte leukemias of T-cell and B-cell ...
Till date different kinds of autologous and allogenic immune cells such as lymphokine-activated killer(LAK)cells, Natural ... Kimura H, Yamaguchi Y (July 1997). "A phase III randomized study of interleukin-2 lymphokine-activated killer cell ... Upon encountering a tumor cell, the activated NK cell attaches to the membrane of the cancer cell and injects toxic granules ... In less than five minutes, the cancer cell dies and the NK cell moves on to its next target cancer cell. A single NK cell can ...
... killer cells, natural MeSH A11.118.637.555.567.537.500 - killer cells, lymphokine-activated MeSH A11.118.637.555.567.550 - ... cho cells MeSH A11.251.210.505 - l cells (cell line) MeSH A11.251.210.520 - llc-pk1 cells MeSH A11.251.210.700 - 3t3 cells MeSH ... activated killer MeSH A11.627.624.880 - u937 cells MeSH A11.627.635.350 - granulocyte precursor cells MeSH A11.635.500.700 - ... activated killer MeSH A11.872.378.590 - myeloid progenitor cells MeSH A11.872.378.590.270 - erythroid progenitor cells MeSH ...
... killer cells, natural MeSH A15.145.229.637.555.567.537.500 - killer cells, lymphokine-activated MeSH A15.145.229.637.555.567. ... killer cells MeSH A15.382.490.555.567.537 - killer cells, natural MeSH A15.382.490.555.567.537.500 - killer cells, lymphokine- ... activated killer MeSH A15.378.316.340 - granulocytes MeSH A15.378.316.340.350 - granulocyte precursor cells MeSH A15.378. ... foam cells MeSH A15.382.680.397.376 - giant cells, foreign-body MeSH A15.382.680.397.380 - giant cells, langhans MeSH A15.382. ...
... suppress natural killer cell lysis and significantly reduce lymphokine-activated killer cell viability and recovery. ... Furthermore, genetic alterations in asbestos-activated macrophages may result in the release of potent mesothelial cell ... Also, heating itself damages the malignant cells more than the normal cells.[citation needed] Multimodal therapy, which ... Mesothelioma cells proved susceptible to in vitro lysis by LAK cells following activation by interleukin-2 (IL-2), but patients ...
ISO 4217 currency code Lymphokine-activated killer cell Aklavik/Freddie Carmichael Airport, Northwest Territories, Canada, IATA ...
Junctional diversity Killer activation receptor Kinase tyrosine-based inhibitory motif Kinetic-segregation model of T cell ... binding protein Low-affinity nerve growth factor receptor LPHN1 Lymphocyte function-associated antigen 1 Lymphokine ... Psychosomatic medicine PtERV1 Pus Rabbit hybridoma RANK RANKL Recombination signal sequences Recombination-activating gene ... CCR9 CCRL1 CCRL2 CD117 CD32B CD4 CD4+ T cells and antitumor immunity CD74 CD94/NKG2 Cell-mediated immunity CELSR1 Central ...
"Activation and expression of the nuclear factors of activated T cells, NFATp and NFATc, in human natural killer cells: ... and lymphokine genes and expression of their products in human natural killer cells". The Journal of Experimental Medicine. 167 ... This CD16-induced expression of cytokine mRNA in NK cells is mediated by the nuclear factor of activated T cells (NFATp), a ... While FcγRIIIa is expressed on mast cells, macrophages, and natural killer cells as a transmembrane receptor, FcγRIIIb is only ...
IFNγ signaling can initially originate from Natural Killer (NK) cells, but adaptive immune cells are required to sustain a ... A macrophage-activating factor (MAF) is a lymphokine or other receptor based signal that primes macrophages towards ... The phrase 'alternatively activated macrophage' is used to refer to M2 macrophages. Regulatory macrophages do not fit into the ... Macrophage-Activating+Factors at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Cytokines). ...
LAK cells (Lymphokine-activated killer) are a laboratory/clinical subset of NK Cells promoted by IL-2 to attack tumor cells. ... B cells Large Pre-B cells => Small Pre-B cells Immature B cells B Cells => (B1 cells; B2 cells) Plasma cells Pro-T cells T- ... natural killer cells (NKs) and (4) dendritic cells (DCs). T cells, B cells and NK cells (and all other Innate lymphoid cells) ... NKT cells see Natural Killer T cell main article Natural Killer T Cells. Human NK T cells are a unique population (which ...
65 kDa immunoglobulin-like transmembrane glycoprotein expressed on the surface of natural killer cells, NK T cell, B cells, ... NK cells activated with interferon α can kill HCV-infected cells in a DNAM-1 dependent manner. During the bacterial infection ... dendritic cells, monocytes and on infected or transformed cells. DNAM-1 promotes lymphocyte signaling, lymphokine secretion and ... 2006). "Expression of human CD226 on T cells and natural killer cells and of soluble CD226 in plasma of HIV-1-infected Chinese ...
... lymphokine-activated killer cell - lymphoma - lymphomatoid granulomatosis - lymphoproliferative disorder - lymphosarcoma - ... cell - cell differentiation - cell motility - cell proliferation - cell respiration - cell adhesion - cellular adoptive ... systemic therapy T cell - T-3 - T-cell depletion - T-cell lymphoma - T138067 - T4N5 liposomal lotion - T900607 - TAC-101 - ... basal cell - basal cell carcinoma - basal cell nevus syndrome - basophil - batimastat - BAY 12-9566 - BAY 43-9006 - BAY 56-3722 ...
... kidney mesangial cells, Langerhans cells, dermal dendritic cells, natural killer cells, large granular lymphocytes, microglia, ... IL-1α is also known as fibroblast-activating factor (FAF), lymphocyte-activating factor (LAF), B-cell-activating factor (BAF), ... Lymphokine Research. 5 (2): 105-18. PMID 3486328. Barland CO, Zettersten E, Brown BS, Ye J, Elias PM, Ghadially R (Feb 2004). " ... IL-1α is produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It ...
IL-13 is a cytokine secreted by T helper type 2 (Th2) cells, CD4 cells, natural killer T cell, mast cells, basophils, ... secretion from activated human B cells. Deletion of IL-13 from mice does not markedly affect either Th2 cell development or ... March 1993). "Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses". Nature. 362 (6417): 248- ... Most normal cells, such as immune cells or endothelial cells, express very low or undetectable levels of IL-13 receptors. ...
... lymphocyte activating factor, mitogenic protein, T-cell replacing factor III, B-cell activating factor, B-cell differentiation ... IL2 is a lymphokine that induces the proliferation of responsive T cells. In addition, it acts on some B cells, via receptor- ... Zhang C, Zhang J, Niu J, Zhou Z, Zhang J, Tian Z (Aug 2008). "Interleukin-12 improves cytotoxicity of natural killer cells via ... The protein, which exists in vivo as a monomer, is produced in activated T cells and mast cells, and is activated by the ...
On the other side of things, there are natural killer cells; these cells have the ability to take down larger in size threats ... Besedovsky HO, Del Rey A, Sorkin E (1986). "Integration of Activated Immune Cell Products in Immune Endocrine Feedback Circuits ... a unique lymphokine made by normal T lymphocytes and a T cell hybridoma". Journal of Immunology. 132 (2): 821-7. doi:10.4049/ ... and T helper cells (Th1 cells), but upregulates interleukin 4, interleukin 10, and interleukin 13 by Th2 cells. This results in ...
August 2004). "The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and ... February 2009). "A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity". Nature. 457 (7230 ... In addition, IL-26 activates extracellular signal-regulated kinases (ERK)-1/2, c-Jun N-terminal kinase (JNK), mitogen-activated ... CD4+ T cells polarized toward a regulatory phenotype (Treg), naïve CD4+ T cells, and T helper 2 cells show low or no expression ...