... also known as cytokeratin 3 is a protein that in humans is encoded by the KRT3 gene. Keratin 3 is a type II ... It is specifically found in the corneal epithelium together with keratin 12. Mutations in the KRT3 encoding this protein have ... v t e (Genes on human chromosome 12, Keratins, All stub articles, Human chromosome 12 gene stubs). ... "Mutations in cornea-specific keratin K3 or K12 genes cause Meesmann's corneal dystrophy". Nat. Genet. 16 (2): 184-7. doi: ...
... is a protein that in humans is encoded by the KRT12 gene. Keratin 12 is keratin found expressed in corneal epithelia ... 2000). "A novel keratin 12 mutation in a German kindred with Meesmann's corneal dystrophy". Br J Ophthalmol. 84 (5): 527-30. ... Chen YT, Tseng SH, Chao SC (2005). "Novel mutations in the helix termination motif of keratin 3 and keratin 12 in 2 Taiwanese ... 2004). "A novel arginine substitution mutation in 1A domain and a novel 27 bp insertion mutation in 2B domain of keratin 12 ...
Alpha-keratin (α-keratin) is a type of keratin found in vertebrates. It is the key structural material making up scales, hair, ... Keratin-associated proteins (KRTAPs) List of cutaneous conditions caused by mutations in keratins List of keratins expressed in ... The human genome has 54 functional annotated Keratin genes, 28 are in the Keratin type 1 family, and 26 are in the Keratin type ... For example, mouse thymic epithelial cells react with antibodies for keratin 5, keratin 8, and keratin 14. These antibodies are ...
The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein ... "Entrez Gene: KRT34 keratin 34". Yu J, Yu DW, Checkla DM, et al. (1993). "Human hair keratins". J. Invest. Dermatol. 101 (1 ... Keratin, type I cuticular Ha4 is a protein that in humans is encoded by the KRT34 gene. ... The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. 34βE12 ...
Structurally, the cyst is lined by thin epithelium and shows a lumen usually filled with desquamated keratin, occasionally ... and filled with keratin. Bohn also classified cysts in the alveolar ridges as mucous gland cysts. However, a century later it ... and are filled with keratin. They are caused by entrapped epithelium (fissural cyst) during the development of the palate. ... They are small white or yellow cystic vesicles (1 to 3 mm in size) often seen in the median palatal raphe of the mouth of ...
... is a protein that in humans is encoded by the KRT16 gene. Keratin 16 is a type I cytokeratin. It is paired with ... 2008). "Keratin and filaggrin expression in keratoacanthoma". J Eur Acad Dermatol Venereol. 22 (3): 353-5. doi:10.1111/j.1468- ... Rosenberg M, RayChaudhury A, Shows TB, Le Beau MM, Fuchs E (February 1988). "A group of type I keratin genes on human ... Rosenberg M, Fuchs E, Le Beau MM, Eddy RL, Shows TB (1991). "Three epidermal and one simple epithelial type II keratin genes ...
Both epithelial keratins and hard keratins can be further subdivided into type I (acidic) keratins and type II (neutral-basic) ... Keratins form heteropolymers consisting of a type I and a type II keratin. Keratins are generally expressed in particular pairs ... "keratins" or are sometimes referred to as "epithelial keratins" or "cytokeratins". The specialized keratins of hair and nail ... Keratin 6C (protein name K6C; gene name KRT6C), is a type II cytokeratin, one of a number of isoforms of keratin 6 encoded by ...
Is co-expressed with and binds to Keratin 10, a Type I keratin, to form a coiled coil heterotypic keratin chain. Keratin 1 and ... This difference is likely due to Keratin 9, rather than Keratin 10, being the major binding partner of Keratin 1 in acral (palm ... In contrast, basal layer keratinocytes express little to no Keratin 1. Mutations in KRT1, the gene encoding Keratin 1, have ... "New mutations in keratin 1 that cause bullous congenital ichthyosiform erythroderma and keratin 2e that cause ichthyosis ...
... is a member of the type I keratin family of intermediate filament proteins. Keratin 14 was the first type I keratin ... Keratin 14 is also known as cytokeratin-14 (CK-14) or keratin-14 (KRT14). In humans it is encoded by the KRT14 gene. Keratin 14 ... Chan Y, Anton-Lamprecht I, Yu QC, Jäckel A, Zabel B, Ernst JP, Fuchs E (November 1994). "A human keratin 14 "knockout": the ... Rosenberg M, Fuchs E, Le Beau MM, Eddy RL, Shows TB (1991). "Three epidermal and one simple epithelial type II keratin genes ...
... is a protein that in humans is encoded by the KRT9 gene. Keratin 9 is a type I cytokeratin. It is found only in the ... "Keratin 9 point mutation in the pedigree of epidermolytic hereditary palmoplantar keratoderma perturbs keratin intermediate ... 2009). "Keratin-9 gene mutation in epidermolytic palmoplantar keratoderma combined with knuckle pads in a large Chinese family ... Endo H, Hatamochi A, Shinkai H (1997). "A novel mutation of a leucine residue in coil 1A of keratin 9 in epidermolytic ...
... is one of the 27 different type II keratins expressed in humans. Keratin 6A was the first type II keratin sequence ... Both epithelial keratins and hard keratins can be further subdivided into type I (acidic) keratins and type II (neutral-basic) ... The expression of keratin 6A is often tested together with keratin 5, using CK5/6 antibodies, which target both keratin forms. ... Keratins form heteropolymers consisting of a type I and a type II keratin. Keratins are generally expressed in particular pairs ...
... , or α-keratin, is a type of keratin found in mammalian vertebrates. This protein is the primary component in ... Under high tension, alpha-keratin can even change into beta-keratin, a stronger keratin formation that has a secondary ... a type I alpha-keratin, to form the alpha-keratin complex of the epidermis layer of cells in the skin. Hard alpha-keratins, ... Alpha-keratins proteins can be one of two types: type I or type II. There are 54 keratin genes in humans, 28 of which code for ...
... also known as keratin 2E or keratin 2 is a protein that in humans is encoded by the KRT2A gene. Keratin 2A is a type ... 2001). "New mutations in keratin 1 that cause bullous congenital ichthyosiform erythroderma and keratin 2e that cause ... Keratin-2 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Genes on human chromosome 12, ... 1998). "A glutamate to lysine mutation at the end of 2B rod domain of keratin 2e gene in ichthyosis bullosa of Siemens". Acta ...
... , often abbreviated CK20, is a protein that in humans is encoded by the KRT20 gene. Keratin 20 is a type I ... "New consensus nomenclature for mammalian keratins". J. Cell Biol. 174 (2): 169-74. doi:10.1083/jcb.200603161. PMC 2064177. PMID ... Keratins, All stub articles, Human chromosome 17 gene stubs). ... 3): 261-3. PMID 12515621. Schweizer J, Bowden PE, Coulombe PA, ... 24 (3): 261-8. doi:10.1007/s00384-008-0613-y. PMID 19119477. S2CID 10831713. Wong CS, Cheung MT, Ma BB, et al. (2008). " ...
Keratin, type II cytoskeletal 8 also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that is encoded in ... Keratin 8 is often used together with keratin 18 and keratin 19 to differentiate cells of epithelial origin from hematopoietic ... "Keratin 8 phosphorylation by p38 kinase regulates cellular keratin filament reorganization: modulation by a keratin 1-like ... Keratin-8 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Genes on human chromosome 12, Keratins). ...
Phylogenetic studies of β-keratin sequences show that feather β-keratins evolved from scale β-keratins. The scale β-keratins ... alpha-keratin and beta-keratin. Alpha-keratin is seen in humans and other mammals, beta-keratin is present in birds and ... Beta-keratin (β-keratin) is a member of a structural protein family found in the epidermis of reptiles and birds. Beta-keratins ... Beta-keratin is harder than alpha-keratin. Structurally alpha-keratin have alpha-helical coiled coil structure while beta- ...
... (or cytokeratin 13) is a protein that in humans is encoded by the KRT13 gene. Keratin 13 is a type I cytokeratin, it ... 1999). "Identification of two novel mutations in keratin 13 as the cause of white sponge naevus". Oral Dis. 5 (4): 321-4. doi: ... 2001). "A novel mutation in the keratin 13 gene causing oral white sponge nevus". J. Dent. Res. 80 (3): 919-23. doi:10.1177/ ... Richard G, De Laurenzi V, Didona B, Bale SJ, Compton JG (December 1995). "Keratin 13 point mutation underlies the hereditary ...
Keratin, type I cytoskeletal 17 is a protein that in humans is encoded by the KRT17 gene. Keratin 17 is a type I cytokeratin. ... "Keratin 16 and keratin 17 mutations cause pachyonychia congenita". Nat Genet. 9 (3): 273-8. doi:10.1038/ng0395-273. PMID ... "Entrez Gene: KRT17 keratin 17". Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, ... Keratin 17 has been shown to interact with CCDC85B. GRCh38: Ensembl release 89: ENSG00000128422 - Ensembl, May 2017 GRCm38: ...
... or keratin-7 (K7) or sarcolectin (SCL) is a protein that in humans is encoded by the KRT7 gene. Keratin 7 is a type II keratin ... Keratin-7 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are ... "Entrez Gene: KRT7 keratin 7". Leong, Anthony S-Y; Cooper, Kumarason; Leong, F Joel W-M (2003). Manual of Diagnostic Cytology (2 ... Keratin-7 is found in simple glandular epithelia, and in transitional epithelium. Epithelial cells of the lung and breast both ...
... is a type II cytokeratin, one of a number of isoforms of keratin 6. It is found with keratin 16 and/or keratin 17 in ... This keratin 6 isoform is thought be less abundant than the closely related keratin 6A protein. Mutations in the gene encoding ... March 1995). "Keratin 16 and keratin 17 mutations cause pachyonychia congenita". Nat. Genet. 9 (3): 273-8. doi:10.1038/ng0395- ... Keratin 6B is associated with the PC-K6B subtype of pachyonychia congenita. McLean WH, Rugg EL, Lunny DP, et al. ( ...
Whittock NV, Eady RA, McGrath JA (January 2000). "Genomic organization and amplification of the human keratin 15 and keratin 19 ... Keratin 15 is a protein that in humans is encoded by the KRT15 gene. It has also been referred to as cytokeratin 15, K1CO and ... Keratin 15 is a type I cytokeratin. It is well-expressed in the basal layer of complex epithelia. However, acral keratinocytes ... Marchuk D, McCrohon S, Fuchs E (March 1985). "Complete sequence of a gene encoding a human type I keratin: sequences homologous ...
Keratin, type I cytoskeletal 4 also known as cytokeratin-4 (CK-4) or keratin-4 (K4) is a protein that in humans is encoded by ... "Allelic variations of human keratins K4 and K5 provide polymorphic markers within the type II keratin gene cluster on ... Keratin 4 is a type II cytokeratin. It is specifically found in differentiated layers of the mucosal and esophageal epithelia ... Chao SC, Tsai YM, Yang MH, Lee JY (June 2003). "A novel mutation in the keratin 4 gene causing white sponge naevus". Br. J. ...
... is a type I keratin. Keratin 19 is a member of the keratin family. The keratins are intermediate filament proteins ... Keratin 19 is often used together with keratin 8 and keratin 18 to differentiate cells of epithelial origin from hematopoietic ... Keratin, type I cytoskeletal 19 also known as cytokeratin-19 (CK-19) or keratin-19 (K19) is a 40 kDa protein that in humans is ... Keratin 19 is a type I keratin. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic ...
... is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic ... Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found ... 1996). "Dynamics of human keratin 18 phosphorylation: polarized distribution of phosphorylated keratins in simple epithelial ... Keratin 18 has been shown to interact with Collagen, type XVII, alpha 1, DNAJB6, Pinin and TRADD. GRCh38: Ensembl release 89: ...
... (AKD) is an emerging disease among wild birds in North America characterized by overgrowth and ... West, George C. (October 1959). "Effects of High Air Temperature on the Bill and Claw Keratin Structures of the Tree Sparrow". ... Zylberberg, Maxine; Van Hemert, Caroline; Handel, Colleen M.; DeRisi, Joseph L. (2018-06-15). "Avian keratin disorder of Alaska ... Wikimedia Commons has media related to Avian keratin disorder. (Articles with short description, Short description matches ...
Human Muse cells homed to the mouse epidermis expressed keratin 14 and human desmoglein-3. Notably, all the mice in the Muse ... 3][1][4][5][6] ] In the bone marrow, they represent one out of 3000 mono-nucleated cells. Other than mesenchymal tissues, Muse ... Y Fujita 1 2, T Nohara 1, S Takashima 1, K Natsuga 1, M Adachi 3, K Yoshida 3, S Shinkuma 4, T Takeichi 5, H Nakamura 1, O Wada ... Needless to inform that the positive SSEA-3 cells or Muse cells are fresh for maximum one day after sorting and if you sort the ...
These two groups of keratins were named as type I and type II keratins. These two categories also represent the first two ... The first sequences of keratins revealed that keratins could be grouped into two categories based on their sequence homologies ... Keratins Skin Epidermis Hanukoglu, I.; Fuchs, E. (Nov 1982). "The cDNA sequence of a human epidermal keratin: divergence of ... "The cDNA sequence of a Type II cytoskeletal keratin reveals constant and variable structural domains among keratins". Cell. 33 ...
The protein encoded by this gene is a member of the keratin gene family. It is one of the type I hair keratin genes which are ... "Entrez Gene: KRT33B keratin 33B". Yu J, Yu DW, Checkla DM, et al. (1993). "Human hair keratins". J. Invest. Dermatol. 101 (1 ... As a type I hair keratin, it is an acidic protein which heterodimerizes with type II hair keratin to form hair and nails. There ... Rogers MA, Schweizer J, Kreig T, Winter H (Nov 1995). "A novel human type I hair keratin gene: evidence for two keratin hHa3 ...
The protein encoded by this gene is a member of the keratin gene family. It is one of the type I hair keratin genes which are ... "Entrez Gene: KRT33A keratin 33A". Yu J, Yu DW, Checkla DM, et al. (1993). "Human hair keratins". J. Invest. Dermatol. 101 (1 ... As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. There are ... Rogers MA, Schweizer J, Kreig T, Winter H (Nov 1995). "A novel human type I hair keratin gene: evidence for two keratin hHa3 ...
These studies were published in the absence of knowledge of a keratin sequence. The first keratin sequences were determined by ... "The cDNA sequence of a Type II cytoskeletal keratin reveals constant and variable structural domains among keratins". Cell. 33 ... Hanukoglu I, Fuchs E (Nov 1982). "The cDNA sequence of a human epidermal keratin: divergence of sequence but conservation of ... These models have been confirmed by structural analyses of coiled-coil domains of keratins. Coiled coils usually contain a ...