... isoleucine-transfer RNA ligase, isoleucine-tRNA synthetase, and isoleucine translase. This enzyme participates in valine, ... In enzymology, an isoleucine-tRNA ligase (EC 6.1.1.5) is an enzyme that catalyzes the chemical reaction ATP + L-isoleucine + ... L-isoleucine, and tRNA(Ile), whereas its 3 products are AMP, diphosphate, and L-isoleucyl-tRNA(Ile). This enzyme belongs to the ... The systematic name of this enzyme class is L-isoleucine:tRNAIle ligase (AMP-forming). Other names in common use include ...
Pseudomonic acid inhibits isoleucine-tRNA ligase in bacteria, leading to depletion of isoleucyl-tRNA and accumulation of the ... This mechanism of action is shared with furanomycin, an analog of isoleucine. Inhibition of the tRNA ligase/synthase is brought ... Depletion of isoleucyl-tRNA results in inhibition of protein synthesis. The uncharged form of the tRNA binds to the aminoacyl- ... A proposed mode of action of pseudomonic acid as an inhibitor of isoleucyl-tRNA synthetase". The Journal of Biological ...
This enzyme participates in valine, leucine and isoleucine biosynthesis and aminoacyl-trna biosynthesis. As of late 2007, 5 ... and tRNA(Val), whereas its 3 products are AMP, diphosphate, and L-valyl-tRNA(Val). This enzyme belongs to the family of ligases ... The systematic name of this enzyme class is L-valine:tRNAVal ligase (AMP-forming). Other names in common use include valyl-tRNA ... In enzymology, a valine-tRNA ligase (EC 6.1.1.9) is an enzyme that catalyzes the chemical reaction ATP + L-valine + tRNAVal ...
This enzyme participates in valine, leucine and isoleucine biosynthesis and aminoacyl-trna biosynthesis. As of late 2007, 5 ... In enzymology, a leucine-tRNA ligase (EC 6.1.1.4) is an enzyme that catalyzes the chemical reaction ATP + L-leucine + tRNALeu ... and L-leucyl-tRNA(Leu). This enzyme belongs to the family of ligases, to be specific those forming carbon-oxygen bonds in ... aminoacyl-tRNA and related compounds. The systematic name of this enzyme class is L-leucine:tRNALeu ligase (AMP-forming). Other ...
... threonine-tRNA ligase EC 6.1.1.4: leucine-tRNA ligase EC 6.1.1.5: isoleucine-tRNA ligase EC 6.1.1.6: lysine-tRNA ligase EC 6.1. ... valine-tRNA ligase EC 6.1.1.10: methionine-tRNA ligase EC 6.1.1.11: serine-tRNA ligase EC 6.1.1.12: aspartate-tRNA ligase EC ... glycine-tRNA ligase EC 6.1.1.15: proline-tRNA ligase EC 6.1.1.16: cysteine-tRNA ligase EC 6.1.1.17: glutamate-tRNA ligase EC ... glutamine-tRNA ligase EC 6.1.1.19: arginine-tRNA ligase EC 6.1.1.20: phenylalanine-tRNA ligase EC 6.1.1.21: histidine-tRNA ...
"An RNA-modifying enzyme that governs both the codon and amino acid specificities of isoleucine tRNA". Molecular Cell. 12 (3): ... cytidine34 ligase (AMP-forming). This enzyme catalyses the following chemical reaction [tRNAIle2]-cytidine34 + L-lysine + ATP ... "The catalytic flexibility of tRNAIle-lysidine synthetase can generate alternative tRNA substrates for isoleucyl-tRNA synthetase ... TRNAIle-lysidine synthase (EC 6.3.4.19, TilS, mesJ (gene), yacA (gene), isoleucine-specific transfer ribonucleate lysidine ...
... glycine-trna ligase MeSH D08.811.464.263.200.400 - histidine-trna ligase MeSH D08.811.464.263.200.450 - isoleucine-trna ligase ... alanine-tRNA ligase MeSH D08.811.464.263.200.100 - arginine-tRNA ligase MeSH D08.811.464.263.200.150 - aspartate-tRNA ligase ... leucine-trna ligase MeSH D08.811.464.263.200.550 - lysine-trna ligase MeSH D08.811.464.263.200.600 - methionine-trna ligase ... serine-trna ligase MeSH D08.811.464.263.200.800 - threonine-tRNA ligase MeSH D08.811.464.263.200.850 - tryptophan-tRNA ligase ...
MetG1 (Methionine-tRNA ligase) is required for elongation of protein synthesis and the initiation of all mRNA translation ... It is proline and arginine rich and isoleucine, asparagine, phenylalanine, and tyrosine poor. The predicted secondary structure ... tRNA ligase GeneCard. 8orf58 Gene(Protein Coding) Chromosome 8 Open Reading Frame 58. [5]. v t e (Articles with short ... through initiator tRNA(fMet) aminoacylation. An important paralog of this gene is ENSG00000248235. Orthologs of the human gene ...
... tRNA) Triacsin C Thyroid-stimulating hormone (TSH) Thyrotropin-releasing hormone (TRH) Thyroxine (T4) Tocopherol (Vitamin E) ... Lactase Lactic acid Lactose Lanolin Lauric acid Lectin Leptin Leptomycin B Leucine Leukotriene Ligase Lignin Limonene Linalool ... growth factor Integral membrane protein Integrase Integrin Intein Interferon Interleukin Inulin Ionomycin Ionone Isoleucine ... Dextran Dextrin Dicer Dihydrotestosterone DNA DNA polymerase DNA ligase Dopamine Endonuclease Enzyme Ephedrine Epinephrine - ...
In eukaryotic cells, these N-terminal residues are recognized and targeted by ubiquitin ligases, mediating ubiquitination ... but also N-terminal Isoleucine and hence exhibits broad specificity (in comparison to its bacterial counterpart). Varshavsky A ... destabilising residues are modified by the attachment of a Primary destabilising residue by the enzyme leucyl/phenylalanyl-tRNA ...
... the phenylalanine-tRNA ligase beta-subunit, VARS, elongation factor Tu, the RNA polymerase beta-subunit, and the ribosomal ... K. muelleri" is usually capable of synthesizing 8 of its essential amino acids: leucine, valine, threonine, isoleucine, lysine ... K. muelleri" lacks a full set of Aminoacyl tRNA synthetases; surprisingly, however, it possesses all of the genes necessary to ... The proteins used were the DNA polymerase III beta-subunit, initiation factor IF-2, leucyl-tRNA synthetase, ...
... tRNA ↽ − − ⇀ aminoacyl − tRNA + AMP {\displaystyle {\ce {{Aminoacyl-AMP}+ tRNA <=> {aminoacyl-tRNA}+ AMP}}} The combination of ... The aspartate family of amino acids includes: threonine, lysine, methionine, isoleucine, and aspartate. Lysine and isoleucine ... Okazaki fragments are covalently joined by DNA ligase to form a continuous strand. Then, to complete DNA replication, RNA ... This reaction, called tRNA charging, is catalyzed by aminoacyl tRNA synthetase. A specific tRNA synthetase is responsible for ...
L-allo-isoleucine--holo-CmaA peptidyl-carrier protein ligase EC 6.2.1.47: Medium-chain-fatty-acid-(acyl-carrier-protein) ligase ... L-seryl-tRNA(Sec) selenium transferase EC 2.9.1.2: O-phospho-L-seryl-tRNA(Sec):L-selenocysteinyl-tRNA synthase Hydrolytic ... Glutarate-CoA ligase EC 6.2.1.7: Cholate-CoA ligase EC 6.2.1.8: Oxalate-CoA ligase EC 6.2.1.9: Malate-CoA ligase EC 6.2.1.10: ... ligase EC 6.2.1.23: Dicarboxylate-CoA ligase EC 6.2.1.24: Phytanate-CoA ligase EC 6.2.1.25: Benzoate-CoA ligase EC 6.2.1.26: o- ...
tRNA See transfer RNA. tRNA-ligase See aminoacyl-tRNA synthetase. twisting number Contents Top A B C D E F G H I J K L M N O P ... leucine instead of isoleucine) are also often classified as silent, since such mutations usually do not significantly affect ... Each tRNA contains a specific anticodon triplet corresponding to an amino acid that is covalently attached to the tRNA's ... uncharged tRNA A transfer RNA without an attached amino acid. Contrast charged tRNA. underdominance underwinding See negative ...
charged tRNA A transfer RNA to which an amino acid has been attached; i.e. an aminoacylated tRNA. Uncharged tRNAs lack amino ... leucine zipper ligase A class of enzymes which catalyze the joining of large molecules such as nucleic acids by forming one or ... Five amino acids (phenylalanine, isoleucine, threonine, tryptophan, and tyrosine) are both glucogenic and ketogenic. ... and most synthetases are cognate to several different tRNAs according to their specific anticodons. aminoacyl-tRNA (aa-tRNA) A ...