The insulin-like growth factor-binding protein (IGFBP) serves as a transport protein for insulin-like growth factor 1 (IGF-1). ... "Role of insulin-like growth factor binding proteins in the control of IGF actions". Prog. Growth Factor Res. 6 (2-4): 357-66. ... November 1998). "Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): ... ISBN 81-7895-002-2. Insulin-like+growth+factor+binding+proteins at the U.S. National Library of Medicine Medical Subject ...

IGF2R is a multifunctional protein receptor that binds insulin-like growth factor 2 (IGF2) at the cell surface and mannose-6- ... Insulin-like growth factor 2 receptor has been shown to interact with M6PRBP1. The insulin-like growth factor 2 receptor ... Ilvesmäki V, Blum WF, Voutilainen R (1994). "Insulin-like growth factor binding proteins in the human adrenal gland". Mol. Cell ... Zhou J, Bondy C (1992). "Insulin-like growth factor-II and its binding proteins in placental development". Endocrinology. 131 ( ...

1993). "Binding of mutants of human insulin-like growth factor II to insulin-like growth factor binding proteins 1-6". J. Biol ... 1999). "Insulin-like growth factors (IGF-I, free IGF-I and IGF-II) and insulin-like growth factor binding proteins (IGFBP-2, ... "Entrez Gene: IGFBP6 insulin-like growth factor binding protein 6". Wood AW, Duan C, Bern HA (2005). "Insulin-like growth factor ... 2001). "Transferrin is an insulin-like growth factor-binding protein-3 binding protein". J. Clin. Endocrinol. Metab. 86 (4): ...

Insulin-like growth factor-binding protein 5 (IBF-5) is a protein that in humans is encoded by the IGFBP5 gene. An IGFBP5 gene ... 1999). "Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF ... Nam TJ, Busby W, Clemmons DR (1997). "Insulin-like growth factor binding protein-5 binds to plasminogen activator inhibitor-I ... Kiefer MC, Ioh RS, Bauer DM, Zapf J (1991). "Molecular cloning of a new human insulin-like growth factor binding protein". ...

2007). "N-Acetylgalactosaminyltransferase 14, a novel insulin-like growth factor binding protein-3 binding partner". Biochem. ... 2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and ... GALNT enzymes catalyze the first step in the O-glycosylation of mammalian proteins by transferring N-acetyl-D-galactosamine ( ... 2 (4): 630-640. doi:10.3892/mco.2014.294. PMC 4051573. PMID 24940508. Wu C, Yao G, Zou M, et al. ( ...

"Transferrin binds insulin-like growth factors and affects binding properties of insulin-like growth factor binding protein-3". ... "Factors regulating insulin-like growth factor-binding protein-3 binding, processing, and potentiation of insulin-like growth ... "Interaction of insulin-like growth factor binding protein-3 with latent transforming growth factor-beta binding protein-1". ... of insulin-like growth factor binding proteins and of the acid-labile subunit of the insulin-like growth factor ternary binding ...

"Transferrin binds insulin-like growth factors and affects binding properties of insulin-like growth factor binding protein-3". ... "Transferrin is an insulin-like growth factor-binding protein-3 binding protein". The Journal of Clinical Endocrinology and ... Transferrin has been shown to interact with insulin-like growth factor 2 and IGFBP3. Transcriptional regulation of transferrin ... Some invertebrates have proteins that act like transferrin found in the hemolymph. When not bound to iron, transferrin is known ...

Insulin-like growth factor-binding protein 2 is a protein that in humans is encoded by the IGFBP2 gene. GRCh38: Ensembl release ... Bach LA, Rechler MM (1996). "Measurement of insulin-like growth factor (IGF)-II binding to purified IGF binding proteins 1-6: ... 1991). "Two insulin-like growth factor (IGF)-binding proteins are responsible for the selective affinity for IGF-II of ... Chesik D, De Keyser J, Wilczak N (2007). "Insulin-like growth factor binding protein-2 as a regulator of IGF actions in CNS: ...

... insulin-like growth factor binding protein 1". Rajaram S, Baylink DJ, Mohan S (1998). "Insulin-like growth factor- ... Insulin-like growth factor-binding protein 1 (IBP-1) also known as placental protein 12 (PP12) is a protein that in humans is ... The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein ... 1993). "Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by ...

"Binding of mutants of human insulin-like growth factor II to insulin-like growth factor binding proteins 1-6". J. Biol. Chem. ... This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP ... "Purification of a colon cancer cell growth inhibitor and its identification as an insulin-like growth factor binding protein". ... The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non- ...

"Growth hormone binding protein, insulin-like growth factor-I and short stature in two pygmy populations from the Philippines". ... associated with low serum levels of insulin-like growth factor 1 and short stature. African Pygmies live in several ethnic ... Other evidence points towards unusually low levels of expression of the genes encoding the growth hormone receptor and growth ... Rozzi, Fernando V. Ramirez; Koudou, Yves; Froment, Alain; Le Bouc, Yves; Botton, Jérémie (2015-07-28). "Growth pattern from ...

"The heparin binding domain of insulin-like growth factor binding protein (IGFBP)-3 increases susceptibility of IGFBP-3 to ... factor IXa, factor Xa, factor XIa, factor XIIa, plasma kallikrein, and trypsin with amino acid and peptide thioesters: ... Thompson RE, Mandle R, Kaplan AP (1980). "Studies of binding of prekallikrein and Factor XI to high molecular weight kininogen ... Fujikawa K, Chung DW, Hendrickson LE, Davie EW (1986). "Amino acid sequence of human factor XI, a blood coagulation factor with ...

"Association of insulin-like growth factor I and insulin-like growth factor-binding protein-3 with intelligence quotient among 8 ... "Effect of insulin on the hepatic production of insulin-like growth factor-binding protein-1 (IGFBP-1), IGFBP-3, and IGF-I in ... The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system ... Insulin-like growth factor 2 (IGF-2, at times IGF-II) is thought to be a primary growth factor required for early development ...

"IGFALS insulin like growth factor binding protein acid labile subunit [Homo sapiens (human)]". NCBI - Gene. Retrieved 6 May ... "CCAAT/Enhancer-binding Protein Family Members Recruit the Coactivator CREB-binding Protein and Trigger Its Phosphorylation". ... "TATA-binding proteins". InterPro. Retrieved 6 May 2019. "SRY Gene". Genetics Home Reference. Vihervaara A, Sistonen L (2014). " ... 2016). "Heparin Decreases in Tumor Necrosis Factor α (TNFα)-induced Endothelial Stress Responses Require Transmembrane Protein ...

"Localization of the insulin-like growth factor I receptor binding sites for the SH2 domain proteins p85, Syp, and GTPase ... the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, ... tid gene defines a novel Ras GTPase-activating protein (RasGAP)-binding protein". J. Biol. Chem. 276 (16): 13087-95. doi: ... Sánchez-Margalet V, Najib S (October 2001). "Sam68 is a docking protein linking GAP and PI3K in insulin receptor signaling". ...

"Localization of the insulin-like growth factor I receptor binding sites for the SH2 domain proteins p85, Syp, and GTPase ... direct binding of the adapter protein Nck to the GTPase-activating protein-associated protein p62 by epidermal growth factor". ... Growth hormone receptor, HoxA10, Insulin receptor, Insulin-like growth factor 1 receptor, IRS1, Janus kinase 1, Janus kinase 2 ... Carter-Su C, Rui L, Stofega MR (2000). "SH2-B and SIRP: JAK2 binding proteins that modulate the actions of growth hormone". ...

2001). "Insulin-like growth factor binding proteins (IGFBPs) as potential physiological substrates for human kallikreins hK2 ... Kallikrein-2 is a protein that in humans is encoded by the KLK2 gene, and is particularly associated with prostatic tissue. ... 41 (4): 222-226. doi:10.1159/000154005. PMID 1783409. Schedlich LJ, Bennetts BH, Morris BJ (1988). "Primary structure of a ... 94 (4): 558-563. doi:10.1002/ijc.1501. PMID 11745444. S2CID 2826757. The MEROPS online database for peptidases and their ...

... , also known as pregnancy-associated plasma protein A, and insulin-like growth factor binding protein-4 protease is ... PAPPA is a secreted protease whose main substrate is insulin-like growth factor binding proteins. Pappalysin-1 is also used in ... PAPPA encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). PAPPA's ... Cleavage of the Met135-Lys bond in insulin-like growth factor binding protein (IGFBP)-4, and the Ser143-Lys bond in IGFBP-5 ...

Sara, V. R.; Hall, K. (July 1990). "Insulin-like growth factors and their binding proteins". Physiological Reviews. 70 (3): 591 ... Insulin growth factor-1 (IGF-1) is a hormone that is structurally very similar to insulin and mediates the effects of growth ... Laron, Z (1 October 2001). "Insulin-like growth factor 1 (IGF-1): a growth hormone". Molecular Pathology. 54 (5): 311-316. doi: ... Yamamoto, H; Murphy, L J (December 1994). "Generation of des-(1-3) insulin-like growth factor-I in serum by an acid protease". ...

... direct effects on steroidogenesis and insulin-like growth factor binding protein-1 (IGFBP-1) production". J Clin Endocrinol ... Poretsky and his coworkers also characterized related receptors in the ovary (insulin-like growth factor receptors, peroxisome- ... Poretsky, L; Smith, D; Seibel, M; Pazianos, A; Moses, AC; Flier, JS (1984). "Specific insulin binding sites in human ovary". J ... describing and characterizing insulin receptors in the human ovary. Before his research, the hormone insulin had been known to ...

Rajaram S, Baylink DJ, Mohan S. Insulin-like growth factor-binding proteins in serum and other biological fluids: regulation ... Linear growth is a complex process regulated by the growth hormone (GH) - insulin-like growth factor-1 (IGF-1) axis, the ... including the growth hormone, vitamin D, and others. These hormones promote the production of insulin-like growth factor-1 (IGF ... Le Roith D. The insulin-like growth factor system. Exp Diabesity Res 2003; 4(4): 205-12. ...

Sui D, Wilson JE (2000). "Interaction of insulin-like growth factor binding protein-4, Miz-1, leptin, lipocalin-type ... PGDS protein is a protein that in humans is encoded by the HPGDS gene. Prostaglandin-D synthase is a sigma class glutathione-S- ... 10 (4): 291-6. doi:10.1038/nsb907. PMID 12627223. S2CID 25214344. Ando M, Murakami Y, Kojima F, et al. (2003). "Retrovirally ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 4, All stub articles, ...

Sui D, Wilson JE (October 2000). "Interaction of insulin-like growth factor binding protein-4, Miz-1, leptin, lipocalin-type ... This protein has a molecular weight of 100 kDa and is composed of two highly similar 50-kDa domains at its N- and C-terminals. ... The transcription factor PU.1 is known to directly activate transcription of the antiapoptotic BCL2A1 gene or inhibit ... Unlike HK1 and HK2, HK3 lacks a mitochondrial binding sequence at its N-terminal. As a cytoplasmic isoform of hexokinase and a ...

Sui D, Wilson JE (Oct 2000). "Interaction of insulin-like growth factor binding protein-4, Miz-1, leptin, lipocalin-type ... Zinc finger and BTB domain-containing protein 17 is a protein that in humans is encoded by the ZBTB17 gene. ZBTB17 has been ... "Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1". The Journal of ... "Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1". The Journal of ...

"Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell ... An expert in the field, Cohen was president of the Growth Hormone Society and served on the Endocrine Society Steering ... Cohen and his team had been screening for proteins that interact with IGFBP3). Other mitochondrial peptides discovered by the ... insulin sensitivity, and inflammatory markers. Aging, 8(4), 796-808. http://doi.org/10.18632/aging.100943. "Small peptides show ...

... binding protein 3 Insulin-like growth factor-binding protein Methyl-CpG-binding domain protein 2 Growth hormone-binding protein ... DNA-binding protein Single-strand binding protein Telomere-binding protein RNA-binding protein Poly(A)-binding protein Nuclear ... binding protein Syntaxin binding protein 2 Oxysterol-binding protein E3 binding protein Iron-responsive element-binding protein ... cap-binding protein complex CREB-binding protein Calcium-binding protein Calcium-binding protein 1 S100 calcium-binding protein ...

... s contain several growth factors. Contents include insulin-like growth factor 1, platelet-derived growth factors, ... which is a heparin-binding chemokine) and other clotting proteins (such as thrombospondin, fibronectin, factor V, and von ... v t e v t e (Articles with short description, Short description is different from Wikidata, Growth factors, All stub articles, ... Willebrand factor). The alpha granules express the adhesion molecule P-selectin and CD63. These are transferred to the membrane ...

1994). "CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor- ... Karas M, Koval AP, Zick Y, LeRoith D (2001). "The insulin-like growth factor I receptor-induced interaction of insulin receptor ... proteins and the guanylnucleotide exchange factor SOS are differentially regulated by insulin and epidermal growth factor". J. ... "Identification of Tyr-762 in the platelet-derived growth factor alpha-receptor as the binding site for Crk proteins". Oncogene ...

2 with the insulin-like growth factor-I receptor". The Journal of Biological Chemistry. 273 (37): 24095-101. doi:10.1074/jbc. ... "Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation". The EMBO Journal. 18 (4): 904 ... "Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation". The EMBO Journal. 18 (4): 904 ... "The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop". The EMBO Journal. ...

... including insulin-like growth factor signalling, neuronal architecture, and viral budding. NEDD4 also is an essential protein ... The NDFIP1 and NDFIP2 proteins function as adaptor proteins that can facilitate NEDD4 binding to substrates that lack PY motifs ... In vivo, NEDD4 is involved in the regulation of insulin and insulin-like growth factor (IGF-1) signalling by regulating the ... amount of insulin receptor (IR) and insulin-like growth factor 1 receptor (IGF-1R) on the cell surface. The deletion of NEDD4 ...