Commercially sold indinavir is indinavir anhydrous, which is indinavir with an additional amine in the hydroxyethylene backbone ... Boosted indinavir requires two 400-mg indinavir capsules with 1 to 2 100-mg ritonavir capsules twice a day. In both cases, the ... proved that indinavir was a clinically efficient drug based on data from human trials. They were able to show that indinavir, ... Indinavir wears off quickly after dosing. Unboosted indinavir requires a very precise dosing of 400 mg every eight hours to ...

"Patient Information about Crixivan for HIV (Human Immunodeficiency Virus) Infection" (PDF). Crixivan® (indinavir sulfate) ... such as from indinavir. Where a CT scan is unavailable, an intravenous pyelogram may be performed to help confirm the diagnosis ... with crystals of drug forming within the renal tract in some people currently being treated with agents such as indinavir, ...

October 2001). "Mechanism of indinavir-induced hyperbilirubinemia". Proceedings of the National Academy of Sciences of the ...

Various examples include isotretinoin, indinavir, and sorafenib. Isotretinoin (Accutane), an analog of vitamin A, is a ...

Certain antiretroviral medications (e.g. indinavir, nevirapine, ritonavir, saquinavir, etc.) Progestogens Some anticonvulsants ...

He was prescribed an unusual combination therapy: didanosine, indinavir and hydroxyurea. Hydroxyurea was the most unusual of ...

The first members of this class, saquinavir, ritonavir, and indinavir, were approved in late 1995-1996. Within 2 years, annual ... This lipodystrophy is colloquially known as "Crix belly", after indinavir (Crixivan). The Proteolysis Map Reverse-transcriptase ... 23 Amprenavir Atazanavir Darunavir Fosamprenavir Indinavir Lopinavir Nelfinavir Ritonavir Saquinavir Tipranavir Hepatitis C ...

The design of indinavir was guided by molecular modeling and the X-ray crystal structure of the inhibited enzyme complex. The ... Indinavir, which is a peptidomimetic hydroxyethylene HIV protease inhibitor, reached the market in 1996. ... Four months later, two other protease inhibitors, ritonavir and indinavir, were approved. In 2009, ten protease inhibitors have ... For instance, mutations at Leu90 evidently affect saquinavir and nelfinavir while indinavir activity is affected by mutations ...

Real world applications include Merck's industrial-scale synthesis of anti-HIV drug Crixivan (indinavir); the production of the ...

... indinavir, macrolide antibiotics, mycophenolate, digoxin and prednisolone. Voriconazole is well absorbed orally with a ...

Some of these substrates include colchicine, ciclosporin, dabigatran, digoxin, diltiazem, fexofenadine, indinavir, morphine, ...

... will lower the blood levels of most protease inhibitors, including amprenavir, atazanavir, and indinavir. At lowered ...

September 1997). "A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus ...

Extended follow-up of patients in a study of indinavir at 800 mg q8h (2.4 g/day), 1000 mg q8h (3.0 g/day) and 800 mg q6h (3.2 g ... in addition to providing clinical data leading to FDA approval of lamivudine, indinavir, ritonavir and saquinavir.[citation ...

Using indinavir in combination with the other two drugs did not increase the toxicity of the combination. Indinavir is a ... 2007). "Mitochondrial toxicity of indinavir, stavudine and zidovudine involves multiple cellular targets in white and brown ... zidovudine and indinavir (IDV) cause a decrease in mitochondrial respiration and an increase in mitochondrial mass in fat cells ...

"Treatment with Indinavir, Zidovudine, and Lamivudine in Adults with Human Immunodeficiency Virus Infection and Prior ...

Reduction in indinavir and delavirdine plasma levels have been shown to occur when administered simultaneously with didanosine ...

"Treatment with Indinavir, Zidovudine, and Lamivudine in Adults with Human Immunodeficiency Virus Infection and Prior ...

... indinavir, and prednisolone. Medical treatment has not proven consistently effective. Medical regimens have included tamoxifen ...

... indinavir, marijuana, and cimetidine. A 1997 study found an association between the SSRIs and mammoplasia in 23 (39%) of its 59 ...

People with HIV/AIDS taking atazanavir, darunavir, fosamprenavir, indinavir, lopinavir, nelfinavir, ritonavir, or saquinavir ...

Interactions of MGA include significantly decreased exposure to indinavir, which may necessitate an increased dosage of the ...

Common causes of drug-related cheilitis include Etretinate, Indinavir, Protease inhibitors, Vitamin A and Isotretinoin (a ...

Drugs such as protease inhibitors like Indinavir can also cause disorders of bilirubin metabolism by competitively inhibiting ...

... indinavir, and amantadine); anti-excitotoxic drugs (branched-chain amino acids, threonine, lamotrigine, gabapentin, nimodipine ...

An open-label study of twice daily indinavir 800/ritonavir 200 mg regimen in HIV-infected adults failing a protease inhibitor ...

3TC and indinavir were shown to cause study participants to lower their viral load to undetectable levels. The other was ... Simultaneous vs Sequential Initiation of Therapy With Indinavir, Zidovudine, and Lamivudine for HIV-1 Infection, JAMA, July 1, ...

... , Costatolide, and dihydrocostatolide can be used together with azidothymidine (AZT), indinavir, nelfinavir, and ...

... indinavir, boceprevir, telaprevir, telithromycin, and conivaptan). CYP3A4 inducers(Carbamazepine, rifampin, St. John's Wort, ...

... leading ritonavir and indinavir by a few months. This new class of antiretrovirals played a critical role in the development of ...