Bridget Jones: Bridget Jones is a franchise based on the fictional character with the same name, Bridget Jones. British writer Helen Fielding started her Bridget Jones's Diary column in The Independent in 1995, while chronicling the life of Bridget Jones as a thirtysomething single woman in London as she tries to make sense of life and love with the help of a surrogate "urban family" of friends in the 1990s.CD4 immunoadhesin: CD4 immunoadhesin is a recombinant fusion protein consisting of a combination of CD4 and the fragment crystallizable region.SeroconversionImmunoglobulin heavy chainLennox–Gastaut syndromeImmunoglobulin light chainFramework region: In molecular biology, a framework region is a region in the variable domain of a protein which belongs to the immunoglobulin superfamily, and which is less "variable" than the CDR.Sieved ultraspherical polynomials: In mathematics, the two families c(x;k) and B(x;k) of sieved ultraspherical polynomials, introduced by Waleed Al-Salam, W.R.Immunoglobulin class switching: Immunoglobulin class switching, also known as isotype switching, isotypic commutation or class-switch recombination (CSR), is a biological mechanism that changes a B cell's production of immunoglobulin (antibodies) from one type to another, such as from the isotype IgM to the isotype IgG. During this process, the constant-region portion of the antibody heavy chain is changed, but the variable region of the heavy chain stays the same (the terms "variable" and "constant" refer to changes or lack thereof between antibodies that target different epitopes).Polyclonal B cell response: Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell.Fragment antigen-binding: The fragment antigen-binding (Fab fragment) is a region on an antibody that binds to antigens. It is composed of one constant and one variable domain of each of the heavy and the light chain.ATC code J06: ==J06A Immune sera==Diary TourEva Engvall: Eva Engvall, born 1940, is one of the scientists who invented ELISA in 1971.Eva Engvall, The Scientist 1995, 9(18):8Somatic hypermutation: Somatic hypermutation (or SHM) is a cellular mechanism by which the immune system adapts to the new foreign elements that confront it (e.g.PlasmacytomaAnti-idiotypic vaccine: Anti-idiotypic vaccines comprise antibodies that have three-dimensional immunogenic regions, designated idiotopes, that consist of protein sequences that bind to cell receptors. Idiotopes are aggregated into idiotypes specific of their target antigen.Coles PhillipsSecretory componentMonoclonal antibody therapyHypogammaglobulinemia