SeroconversionCD4 immunoadhesin: CD4 immunoadhesin is a recombinant fusion protein consisting of a combination of CD4 and the fragment crystallizable region.Immunoglobulin heavy chainLennox–Gastaut syndromeImmunoglobulin light chainEva Engvall: Eva Engvall, born 1940, is one of the scientists who invented ELISA in 1971.Eva Engvall, The Scientist 1995, 9(18):8Polyclonal B cell response: Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell.Framework region: In molecular biology, a framework region is a region in the variable domain of a protein which belongs to the immunoglobulin superfamily, and which is less "variable" than the CDR.ATC code J06: ==J06A Immune sera==Toralizumab: IDEC}}Rubella virus: Rubella virus (RuV) is the pathogenic agent of the disease rubella, and is the cause of congenital rubella syndrome when infection occurs during the first weeks of pregnancy.Immunoglobulin class switching: Immunoglobulin class switching, also known as isotype switching, isotypic commutation or class-switch recombination (CSR), is a biological mechanism that changes a B cell's production of immunoglobulin (antibodies) from one type to another, such as from the isotype IgM to the isotype IgG. During this process, the constant-region portion of the antibody heavy chain is changed, but the variable region of the heavy chain stays the same (the terms "variable" and "constant" refer to changes or lack thereof between antibodies that target different epitopes).Sieved ultraspherical polynomials: In mathematics, the two families c(x;k) and B(x;k) of sieved ultraspherical polynomials, introduced by Waleed Al-Salam, W.R.Rheumatoid factor: Rheumatoid factor (RF) is the autoantibody (antibody directed against an organism's own tissues) that was first found in rheumatoid arthritis. It is defined as an antibody against the Fc portion of IgG (an antibody against an antibody).Immunoperoxidase: Immunoperoxidase is a type of immunostain used in molecular biology, medical research, and clinical diagnostics. In particular, immunoperoxidase reactions refer to a sub-class of immunohistochemical or immunocytochemical procedures in which the antibodies are visualized via a peroxidase-catalyzed reaction.Monoclonal antibody therapyFragment antigen-binding: The fragment antigen-binding (Fab fragment) is a region on an antibody that binds to antigens. It is composed of one constant and one variable domain of each of the heavy and the light chain.Anti-idiotypic vaccine: Anti-idiotypic vaccines comprise antibodies that have three-dimensional immunogenic regions, designated idiotopes, that consist of protein sequences that bind to cell receptors. Idiotopes are aggregated into idiotypes specific of their target antigen.PlasmacytomaSAG1 protein domain: In molecular biology, the SAG1 protein domain is an example of a group of glycosylphosphatidylinositol (GPI)-linked proteins named SRSs (SAG1 related sequence). SAG1 is found on the surface of a protozoan parasite Toxoplasma gondii.La Convalescence, les SaintesAssay sensitivity: Assay sensitivity is a property of a clinical trial defined as the ability of a trial to distinguish an effective treatment from a less effective or ineffective intervention. Without assay sensitivity, a trial is not internally valid and is not capable of comparing the efficacy of two interventions.Rubellatoma rubella: Rubellatoma rubella is a species of sea snail, a marine gastropod mollusk in the family Mangeliidae.Diary TourRadial immunodiffusion: Radial immunodiffusion (RID) or Mancini method, Mancini immunodiffusion or single radial immunodiffusion assay, is an immunodiffusion technique used in immunology to determine the quantity or concentration of an antigen in a sample. Antibody is incorporated into a medium such as an agar gel.Immunoelectrophoresis: Immunoelectrophoresis is a general name for a number of biochemical methods for separation and characterization of proteins based on electrophoresis and reaction with antibodies. All variants of immunoelectrophoresis require immunoglobulins, also known as antibodies, reacting with the proteins to be separated or characterized.Hemagglutination assay: The hemagglutination assay (or haemagglutination assay; HA) and the hemagglutination inhibition assay (HI) were developed in 1941–42 by American virologist George Hirst as methods for quantitating the relative concentration of viruses, bacteria, or antibodies.Immunoassay: An immunoassay is a biochemical test that measures the presence or concentration of a macromolecule in a solution through the use of an antibody or immunoglobulin. The macromolecule detected by the immunoassay is often referred to as an "analyte" and is in many cases a protein.ToxoplasmosisColes PhillipsRaji cell: Raji cell line is the first continuous human cell line from hematopoietic origin. The cell lines produce an unusual strain of Epstein-Barr virus which will both transform cord blood lymphocytes and induce early antigens in Raji cells.Hyperimmune globulin: Hyperimmune globulin is similar to intravenous immunoglobulin (IVIG) except that it is prepared from the plasma of donors with high titers of antibody against a specific organism or antigen. Some agents against which hyperimmune globulins are available include hepatitis B, rabies, tetanus toxin, varicella-zoster, etc.Bioline Reagents: Bioline Reagents is a primary manufacturer and developerBioline: The PCR Company | Company Profile of a wide range of specialised molecular biology products for the life science industry and research markets. It manufactures reagents including ultra-pure nucleotides, DNA polymerases and mixes, DNA markers, competent cells, products for RNA analysis and other general reagents for molecular biology.EthanethiolCongenital syphilisPolysaccharide encapsulated bacteriaDirect agglutination test: A direct agglutination test (DAT) is any test that uses whole organisms as a means of looking for serum antibodies. The abbreviation, DAT, is most frequently used for the serological test for visceral leishmaniasis.Prevalence: Prevalence in epidemiology is the proportion of a population found to have a condition (typically a disease or a risk factor such as smoking or seat-belt use). It is arrived at by comparing the number of people found to have the condition with the total number of people studied, and is usually expressed as a fraction, as a percentage or as the number of cases per 10,000 or 100,000 people.Cryptic self epitopes: In immunology, cryptic self epitopes are a source of autoimmunity.ImmunizationSomatic hypermutation: Somatic hypermutation (or SHM) is a cellular mechanism by which the immune system adapts to the new foreign elements that confront it (e.g.Symmetry element: A symmetry element is a point of reference about which symmetry operations can take place. In particular, symmetry elements can be centers of inversion, axes of rotation and mirror planes.Saint Louis University School of Public HealthPeriarteriolar lymphoid sheaths: Periarteriolar lymphoid sheaths (or periarterial lymphatic sheaths, or PALS) are a portion of the white pulp of the spleen. They are populated largely by T cells and surround central arteries within the spleen; the PALS T-cells are presented with blood borne antigens via myeloid dendritic cells.Dengue fever outbreaksNew Zealand rabbitHyper-IgM syndrome type 1Protein primary structure: The primary structure of a peptide or protein is the linear sequence of its amino acid structural units, and partly comprises its overall biomolecular structure. By convention, the primary structure of a protein is reported starting from the amino-terminal (N) end to the carboxyl-terminal (C) end.Autoantibody: An autoantibody is an antibody (a type of protein) produced by the immune system that is directed against one or more of the individual's own proteins. Many autoimmune diseases, (notably lupus erythematosus), are caused by such autoantibodies.Complement deficiency