... can interfere with the Lowry protein assay. Salts of imidazole where the imidazole ring is the cation are known as ... Imidazole and its derivatives have high affinity for metal cations. One of the applications of imidazole is in the purification ... Imidazole is a suitable buffer for pH 6.2 to 7.8,. Pure imidazole has essentially no absorbance at protein relevant wavelengths ... The name "imidazole" was coined in 1887 by the German chemist Arthur Rudolf Hantzsch (1857-1935). Imidazole is a planar 5- ...
... are a group of alkaloidss whose basic structure contains the imidazole ring system. In nature, imidazole ... One well-known imidazole alkaloid is pilocarpine, which is present in the leaves of Paraguay jaborandi. For instance, from the ... A well-known imidazole alkaloid is pilocarpine. Other representatives include. cynodin, cynometrin and odilin. (+)-Pilocarpine ... a variety of imidazole alkaloids, such as 2-deoxy-2-aminokealiiquinone and Naamine C, have been identified. Imbricatin has been ...
Other names in common use include imidazole acetylase, and imidazole acetyltransferase. Kinsky SC (January 1960). "Assay, ... In enzymology, an imidazole N-acetyltransferase (EC 2.3.1.2) is an enzyme that catalyzes the chemical reaction acetyl-CoA + ... The systematic name of this enzyme class is acetyl-CoA:imidazole N-acetyltransferase. ... imidazole ⇌ {\displaystyle \rightleftharpoons } CoA + N-acetylimidazole Thus, the two substrates of this enzyme are acetyl-CoA ...
... (PIPs) are a class of polyamides have the ability to bind to minor grooves found in the DNA helix ... Wu, Chunlei; Wang, Wei; Fang, Lijing; Su, Wu (July 2018). "Programmable pyrrole-imidazole polyamides: A potent tool for DNA ... Kawamoto, Yusuke; Bando, Toshikazu; Sugiyama, Hiroshi (May 2018). "Sequence-specific DNA binding Pyrrole-imidazole polyamides ...
Six imidazole ligands fit comfortably around octahedral metal centers, e.g., [Fe(imidazole)6]2+. The M-N(imidazole) bond is ... A transition metal imidazole complex is a coordination complex that has one or more imidazole ligands. Complexes of imidazole ... Nonetheless, complexes between low-valent metals and imidazole are well known, e.g., [Re(imidazole)3(CO)3]+. Imidazole is a ... Imidazole is a pure sigma-donor ligand. There is no evidence for pi backbonding in metal-imidazole complexes, a property that ...
The Debus-Radziszewski imidazole synthesis is a multi-component reaction used for the synthesis of imidazoles from a 1,2- ... The method is used commercially to produce several imidazoles. The process is an example of a multicomponent reaction. The ... Ebel, K., Koehler, H., Gamer, A. O., & Jäckh, R. "Imidazole and Derivatives." In Ullmann's Encyclopedia of Industrial Chemistry ... affords N-substituted imidazoles in good yields. This reaction has been applied to the synthesis of a range of 1,3- ...
... is an organic azide compound that can be used as an alternative to trifluoromethanesulfonyl azide. ... E. D. Goddard-Borger and R. V. Stick (2007). "An Efficient, Inexpensive, and Shelf-Stable Diazotransfer Reagent: Imidazole-1- ... E. D. Goddard-Borger and R. V. Stick (2011). "An Efficient, Inexpensive, and Shelf-Stable Diazotransfer Reagent: Imidazole-1- ... "Sensitivities of Some Imidazole-1-sulfonyl Azide Salts". J. Org. Chem. 77 (4): 1760-1764. doi:10.1021/jo202264r. PMID 22283437 ...
The enzyme purine imidazole-ring cyclase (EC 4.3.2.4) catalyzes the chemical reaction DNA 4,6-diamino-5-formamidopyrimidine ... "In situ enzymatic reclosure of opened imidazole rings of purines in DNA damaged by γ-irradiation". Proc. Natl. Acad. Sci. U.S.A ...
... imidazole, and one product, 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate. This enzyme belongs to the family of ... imidazole ⇌ {\displaystyle \rightleftharpoons } 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate Hence, this enzyme has ... The systematic name of this enzyme class is 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole carboxymutase. Other names in ... In enzymology, a 5-(carboxyamino)imidazole ribonucleotide mutase (EC 5.4.99.18) is an enzyme that catalyzes the chemical ...
... imidazole The 3 substrates of this enzyme are ATP, 5-amino-1-(5-phospho-D-ribosyl)imidazole ("AIR"), and HCO3−, whereas its 3 ... The systematic name of this enzyme class is 5-amino-1-(5-phospho-D-ribosyl)imidazole:carbon-dioxide ligase (ADP-forming). Meyer ... In enzymology, a 5-(carboxyamino)imidazole ribonucleotide synthase (EC 6.3.4.18) is an enzyme that catalyzes the chemical ... products are ADP, phosphate, and 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole. This enzyme belongs to the family of ligases ...
... (EC 5.3.1.16, N-(5-phospho-D- ... 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide+isomerase at the U.S. National Library ... imidazole-4-carboxamide Margolies MN, Goldberger RF (July 1966). "Isolation of the fourth (isomerase) of histidine biosynthesis ... imidazole-4-carboxamide ketol-isomerase) is an enzyme with systematic name 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino) ...
It is an imidazole and works by hindering the production of ergosterol required for the fungal cell membrane, thereby slowing ... As an antifungal, ketoconazole is structurally similar to imidazole, and interferes with the fungal synthesis of ergosterol, a ... Ketoconazole is a synthetic imidazole. It is a nonsteroidal compound. It is a racemic mixture of two enantiomers, ... 586-. ISBN 978-3-88763-075-1. Heeres J, Backx LJ, Mostmans JH, Van Cutsem J (August 1979). "Antimycotic imidazoles. part 4. ...
Anti-fungal: imidazoles, polyenes. Anti-glaucoma: adrenergic agonists, beta-blockers, carbonic anhydrase inhibitors/ ...
... is a valuable building block in organic synthesis, especially in the synthesis of heterocycles such as imidazoles. A ... Epub 2017 Jun 8. PMID: 28596309 Snyder, H. R.; Handrick, R. G.; Brooks, L. A. (1942). "Imidazole". Organic Syntheses. 22: 65.; ...
The imidazole antifungals contain a 1,3-diazole (imidazole) ring (two nitrogen atoms), whereas the triazole antifungals have a ... "Imidazole". pubchem.ncbi.nlm.nih.gov. Retrieved 2 December 2022. Ameen M (March 2010). "Epidemiology of superficial fungal ...
Snyder, H. R.; Handrick, R. G.; Brooks, L. A. (1942). "Imidazole". Organic Syntheses.; Collective Volume, vol. 3, p. 471 ...
J., Reedijk; G.C., Verschoor (1973-04-15). "Pyrazoles and imidazoles as ligands. XX. The crystal and molecular structure of ... octahedral geometries for Cadmium tetrafluoroborate complexes with nitrogen-containing ligands such as pyrazoles and imidazoles ...
Purines, pyrimidines, and imidazoles. Part XVII. A synthesis of willardiine". Journal of the Chemical Society (Resumed): 583. ...
With the N-methyl group, this particular derivative of imidazole cannot tautomerize. It is slightly more basic than imidazole, ... Reedijk,R. (1969). "Pyrazoles and imidazoles as ligands. II. Coordination compounds of N-methyl imidazole with metal ... The main one is acid-catalysed methylation of imidazole by methanol. The second method involves the Radziszewski reaction from ... Similarly, 1-methylimidazole may be synthesized by first deprotonating imidazole to form a sodium salt followed by methylation ...
1. Imidazole derivatives". Journal of Medicinal Chemistry. 24 (10): 1139-1148. doi:10.1021/jm00142a005. PMID 7199088. Cross, ... One convenient synthesis starts with the O-chloroethyl ether of p-hydroxybenzamide and proceeds bydisplacement with imidazole ... 1. 1-[(Aryloxy)alkyl]-1H-imidazoles". Journal of Medicinal Chemistry. 28 (10): 1427-1432. doi:10.1021/jm00148a009. PMID 3930740 ... Imidazoles, Benzoic acids, Ethanolamines, All stub articles, Blood and blood forming organ drug stubs). ...
Plasma half-life is 12 to 14 hours.[medical citation needed] Ebel K, Koehler H, Gamer AO, Jäckh R (2002). "Imidazole and ...
This bicyclic compound may be viewed as fused rings of the aromatic compounds benzene and imidazole. It is a white solid that ... doi:10.1002/14356007.a16_487.pub2 Grimmett, M. R. (1997). Imidazole and benzimidazole synthesis. Boston: Academic Press. ISBN 0 ...
Grimmett, M. R. (1997). Imidazole and Benzimidazole Synthesis. Academic Press. pp. 71ff. ISBN 9780080534459. (Articles without ...
... (Preferred IUPAC name: 4,5-dihydro-1H-imidazole) is one of three isomers of the nitrogen-containing heterocycle ... Ishihara M, Togo H (2006). "An Efficient Preparation of 2-Imidazolines and Imidazoles from Aldehydes with Molecular Iodine and ... Imidazoles can be prepared from dehydrogenation of imidazolines. As a structural analogue of 2-oxazolines, 2-imidazolines have ...
These include indoles, flavones, benzoflavones, imidazoles and pyridines. These compounds are metabolized rapidly, but ...
... is an imidazole derivative. Its antifungal activity has been demonstrated in in vivo and in vitro studies to be ... Imidazole antifungals, Lanosterol 14α-demethylase inhibitors, All stub articles, Antiinfective agent stubs, Genito-urinary ...
A novel synthesis of 5-amino-1-(.beta.-D-ribofuranosyl)imidazole-4-carboxamide and 5-amino-1-(.beta.-D-ribopyranosyl)imidazole- ... resulting in the formation of the imidazole ring. Reaction with alkoxide then converts the nitrile nearest the sugar to an ...
... is an antifungal medication of the imidazole class used to treat infections caused by a fungus or yeast. It is ... Antimycotic imidazole derivative. A displacement reaction between 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol and 2- ... Imidazole antifungals, Lanosterol 14α-demethylase inhibitors, Thiophenes). ...
A common base is imidazole. The titration cell also consists of a smaller compartment with a cathode immersed in the anode ...
This variety tolerates imidazole herbicides. It was bred by traditional breeding techniques that are not considered to be ...