Crabbé P, Heremans J (1967). "Selective IgA deficiency with steatorrhea. A new syndrome". Am J Med. 42 (2): 319-26. doi:10.1016 ... Collin P, Mäki M, Keyriläinen O, Hällström O, Reunala T, Pasternack A (1992). "Selective IgA deficiency and coeliac disease". ... The IgG antibody is similar to AGA IgA, but is found at higher levels in patients with the IgA-less phenotype. It is also ... Bateman EA, Ferry BL, Hall A, Misbah SA, Anderson R, Kelleher P (2004). "IgA antibodies of coeliac disease patients recognise a ...

Guidelines recommend that a total serum IgA level is checked in parallel, as people with coeliac with IgA deficiency may be ... ISBN 978-1-4614-8559-9. Cunningham-Rundles C (September 2001). "Physiology of IgA and IgA deficiency". J. Clin. Immunol. 21 (5 ... IgA deficiency is present in 2.3% of people with coeliac disease, and is itself associated with a tenfold increased risk of ... IgG class anti-DGP antibodies may be useful in people with IgA deficiency. In children younger than two years, anti-DGP ...

First to fully describe IgA deficiency. IgM deficiency selective deficiency to staphylococci. Early to recognise a circulating ... now IgA deficiency) Lancet i1968 110-114 Hobbs, J.R. IgM Deficiency (1975) Birth Defects: Original Article Series IX, 1, 112-6 ... Defined secondary deficiencies of B-cells> and T-cells and their possible treatments predictable by cytofluorometry In Bone ... 1972) Nature New Biology 235, 177-178 Hobbs, J.R. Secondary antibody deficiency,1968 Proc.R.Soc.Med. 61, 883-887 Hobbs, J.R. ...

... is also associated with induction of reversible IgA deficiency. Phenytoin may increase risk of suicidal thoughts or ... Gilhus NE, Aarli JA (1981). "The reversibility of phenytoin-induced IgA deficiency". Journal of Neurology. 226 (1): 53-61. doi: ... Vitamin D deficiency, as well as low calcium and phosphate in the blood cause decreased bone mineral density. Phenytoin is an ... Phenytoin acts by inhibiting this enzyme, thereby causing folate deficiency, and thus megaloblastic anemia. Other side effects ...

"TACI is mutant in common variable immunodeficiency and IgA deficiency". Nature Genetics. 37 (8): 829-34. doi:10.1038/ng1601. ...

Use is not recommended in people with some types of IgA deficiency. Use appears to be relatively safe during pregnancy. Human ... to IgG subclass deficiencies (usually involving IgG2 or IgG3), to other disorders in which antibodies are within a normal ... congenital acquired immune deficiency syndrome (AIDS) with recurrent bacterial infections. and for the immunomodulation in ... immunoglobulin-G-subclass deficiencies with recurrent infections; replacement therapy in myeloma or chronic lymphocytic ...

Ambrus M, Hernádi E, Bajtai G (May 1977). "Prevalence of HLA-A1 and HLA-B8 antigens in selective IgA deficiency". Clin. Immunol ... Ostergaard PA, Eriksen J (August 1979). "Association between HLA-A1,B8 in children with extrinsic asthma and IgA deficiency". ... but not with deficiency of serum IgA". Tissue Antigens. 23 (5): 280-3. doi:10.1111/j.1399-0039.1984.tb00046.x. PMID 6611606. ... However, some of this reaction can be attributed to the linkage of the HLA A1-B8-DR3-DQ2 haplotype to the IgA-less phenotype. A ...

Antibody deficiencies are also common, including common variable immunodeficiency and IgA deficiency. T-cell immunity is normal ... Wolf U, Reinwein H, Porsch R, Schröter R, Baitsch H (1965). "[Deficiency on the short arms of a chromosome No. 4]". ... Hanley-Lopez J, Estabrooks LL, Stiehm R (July 1998). "Antibody deficiency in Wolf-Hirschhorn syndrome". The Journal of ...

"Family and linkage study of selective IgA deficiency and common variable immunodeficiency". Clinical Immunology and ... immunoglobulin deficiencies, T-cell defects, and internal medicine. Paganelli is the section editor-in-chief for the journal ... his 2005 study linked positive family history to a higher risk for immunoglobulin A deficiency and common variable ... his analysis of patients with ataxia-telangiectasia revealed a range of immune system abnormalities including deficiencies in ...

September 2010). "Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency". Nature Genetics. 42 ...

IgA deficiency is an exception, and is present in 1 in 500 people. Some of the more frequently seen forms of PID include common ... Immune deficiencies can result in persistent or recurring infections, auto-inflammatory disorders, tumors, and disorders of ... By definition, primary immune deficiencies are due to genetic causes. They may result from a single genetic defect, but most ... Although there is a therapeutic option, gene therapy which has been in a trial for few immune deficiencies affecting the ...

2010). "Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency". Nat. Genet. 42 (9): 777-80. ...

Hauser GJ, Heiman I, Laurian L, Diamant S, Spirer Z (1981). "Selective IgA deficiency with multiple autoimmune disorders". ... Deficiency - Selenium and zinc deficiencies may play a role increasing risk of cancer. Selenium deficiency may also be an ... Anti-gliadin IgA antibodies are found also more commonly in patients with IgA Nephropathy. The paper finds a link between GSE ... Iron-deficiency anemia. Iron-deficiency anemia (IDA) may be the only symptom for CD, detected in subclinical CD and is ...

Finally, IgA deficiency is also sometimes associated with the development of autoimmune and atopic phenomena. Patients with ... T cell deficiency, often causes secondary disorders such as acquired immune deficiency syndrome (AIDS). Granulocyte deficiency ... Humoral immune deficiency (including B cell deficiency or dysfunction), with signs or symptoms depending on the cause, but ... Some deficiencies cause early mortality (before age one), others with or even without treatment are lifelong conditions that ...

Pathogenesis of IgA Deficiency 'In IgA-deficient patients, the common finding is a maturation defect in B cells to produce IgA ... Patients with Selective IgA deficiency rarely have severe reactions to blood transfusions. Although Selective IgA deficiency is ... Cunningham-Rundles C. (1990). "Genetic Aspects of IgA Deficiency". Adv Hum. Genet. Yel, L. (2010). "Selective IgA Deficiency". ... Selective IgA and CVID are found in the same family. Selective IgA deficiency is inherited in less than half of cases, but has ...

Finally, IgA deficiency is also sometimes associated with the development of autoimmune and atopic phenomena.[citation needed] ... patients are advised to avoid sunlight which may be responsible for vitamin D deficiency seen in this disease. Polymorphisms in ...

Greater care should be taken in people with protein S deficiency, IgA deficiency, or heart failure. Fresh frozen plasma is made ... Use in antithrombin III deficiency: FFP can be used as a source of antithrombin III in patients who are deficient of this ... Single-donor plasma is efficacious in the treatment of mild deficiencies of stable clotting factors. It also is of value in ... Indications for the use of FFP include the following: Replacement of isolated factor deficiencies: FFP is used to treat rare ...

Schaffer F, Palermos J, Zhu Z, Barger B, Cooper M, Volanakis J (1989). "Individuals with IgA deficiency and common variable ... Klemola T, Savilahti E, Koskimies S, Pelkonen P (1988). "HLA antigens in IgA deficient paediatric patients". Tissue Antigens. ... DQ2.5 is also linked to the IgA-less phenotype which may or may not increase susceptibility to diseases. This imposes a problem ...

IgA deficiency occurs in 1:500 of the population, as is suggested by a pallor in the gamma zone. Of note, hypogammaglobulinema ... IgA has the most anodal mobility and typically migrates in the region between the beta and gamma zones also causing a beta/ ... Note that immunoglobulins may also be found in other zones; IgA typically migrates in the beta-gamma zone, and in particular, ... A decreased band is seen in the deficiency state. It is decreased in the nephrotic syndrome and absence could indicate possible ...

Certain other immune deficiency states (e.g. common variable immunodeficiency and IgA deficiency) are also associated with ... December 2002). "Cancer risk among patients with IgA deficiency or common variable immunodeficiency and their relatives: a ...

... selective IgA deficiency and acquired immune deficiency syndrome (AIDS). Numerous studies have shown that erythrocyte ... It is believed that lead induced deficiency of the enzyme in maturing erythroid cells is responsible for basophilic stippling ... Boss GR, Thompson LF, O'Connor RD, Ziering RW, Seegmiller JE (April 1981). "Ecto-5'-nucleotidase deficiency: association with ... Such diseases include severe combined immuno-deficiency, Wiskott-Aldrich syndrome, congenital X-linked agammaglobulinemia, ...

CD19 deficiency, TACI (TNFRSF13B) deficiency, BAFF receptor deficiency. Normal numbers of B cells with decreased IgG and IgA ... btk deficiency, or Bruton's agammaglobulinemia), μ-Heavy chain deficiency, l 5 deficiency, Igα deficiency, BLNK deficiency, ... kappa chain deficiency, isolated IgG subclass deficiency, IgA with IgG subsclass deficiency, selective immunoglobulin A ... The most common such immunodeficiency is inherited selective IgA deficiency, occurring between 1 in 100 and 1 in 1000 persons, ...

... only to find out later they actually have selective IgA deficiency. Thus, another possible cause of false positives in a ... commonly seen in EBV infection as well as selective IgA deficiency. Heterophile antigen An immunoassay is a biochemical test, ... "Frequent false positive beta human chorionic gonadotropin tests in immunoglobulin A deficiency". Clinical and Experimental ...

Various proteins, such as antibodies directed against IgA or haptoglobin in people with IgA and haptoglobin deficiency have ... However, the literature is scarce and conflicting as passive infusion of anti-IgA antibodies in to recipients has not been ...

IgA deficiency MeSH C20.673.430.750 - IgG deficiency MeSH C20.673.480.040 - acquired immunodeficiency syndrome MeSH C20.673. ...

... the influence of maternal anti-IgA antibodies on the occurrence of IgA deficiency in the offspring. He and colleagues first ... he demonstrated the relationship of IgA deficiency in childhood rheumatic diseases, ...

Idiopathic thrombocytopenic purpura Iduronate 2-sulfatase deficiency IFAP syndrome IgA deficiency IgA nephropathy IgA ... congenital deficiency of Iodine antenatal infection Iodine deficiency Iophobia Iridocyclitis Iridogoniodysgenesis, dominant ... deficiency Internal carotid agenesis Intraocular lymphoma Interstitial cystitis Interstitial lung disease Interstitial ... Kartagener type Immune deficiency, familial variable Immune thrombocytopenia Immunodeficiency, primary Immunodeficiency, ...

IgA deficiencies, heterophile antibodies, enterocystoplasties, gestational trophoblastic diseases (GTD), and gestational ...

... because people with DOCK8 deficiency have low levels of IgM and an impaired secondary immune response. IgG and IgA levels are ... The signs and symptoms of DOCK8 deficiency are similar to the autosomal dominant form, STAT3 deficiency. However, in DOCK8 ... Children with DOCK8 deficiency do not tend to live long; sepsis is a common cause of death at a young age. CNS and vascular ... DOCK8 deficiency is very rare, estimated to be found in less than one person per million; there have been 32 patients diagnosed ...

Patients show markedly low immunoglobulin levels of IgG, IgA, and IgM. A new investigation has identified a seemingly ... LRBA deficiency presents as a syndrome of autoimmunity, lymphoproliferation, and humoral immune deficiency. Predominant ... LRBA deficiency is a rare genetic disorder of the immune system. This disorder is caused by a mutation in the gene LRBA. LRBA ... LRBA deficiency is caused by biallelic loss-of-function mutations in the gene LRBA. LRBA maps to human chromosome 4q31.3, has ...