Secondary hyperalgesia describes pain sensitivity that occurs in surrounding undamaged tissues. Opioid-induced hyperalgesia may ... Where hyperalgesia has been produced by chronic high doses of opioids, reducing the dose may result in improved pain management ... Hyperalgesia can be experienced in focal, discrete areas, or as a more diffuse, body-wide form. Conditioning studies have ... Hyperalgesia is induced by platelet-activating factor (PAF) which comes about in an inflammatory or an allergic response. This ...
"Victorian Halls released Hyperalgesia @ Bottom Lounge". The Deli Magazine. May 19, 2015. Retrieved June 30, 2017. "Hyperalgesia ... Hyperalgesia is the second full-length studio album by American alternative rock band Victorian Halls. The album, that contains ...
... (OIH) or opioid-induced abnormal pain sensitivity, also called paradoxical hyperalgesia, is an ... Opioid-induced hyperalgesia has also been criticized as overdiagnosed among chronic pain patients, due to poor differential ... Ketamine, an NMDA antagonist, has been shown to prevent the extended use of opioid in post-operative hyperalgesia when it is ... Although tolerance and opioid-induced hyperalgesia both result in a similar need for dose escalation to receive the same level ...
Pöyhiä R, Vainio A (January 2006). "Topically administered ketamine reduces capsaicin-evoked mechanical hyperalgesia". The ... and hyperalgesia. Symptoms may change over time, and they can vary from person to person. The more dynamic symptoms (especially ... Evidence of hyperalgesia (to pinprick) and/or allodynia (to light touch and/or temperature sensation and/or deep somatic ... mechanical hyperalgesia) and showed a "significantly increased activation" of not just the S1 cortex (contralateral), S2 ( ...
Mao J (19 April 2016). Opioid-Induced Hyperalgesia. CRC Press. pp. 127-. ISBN 978-1-4200-8900-4. Archived from the original on ... Lee M, Silverman SM, Hansen H, Patel VB, Manchikanti L (2011). "A comprehensive review of opioid-induced hyperalgesia". Pain ... It may also prevent opioid-induced hyperalgesia and postanesthetic shivering. For chronic pain, ketamine is used as an ...
Hyperalgesia Opioid-induced hyperalgesia (OIH) has been evident in patients after chronic opioid exposure. Adverse effects of ... Opioid induced hyperalgesia more commonly occurs with chronic use or brief high doses but some research suggests that it may ... Opioid-induced hyperalgesia - where individuals using opioids to relieve pain paradoxically experience more pain as a result of ... Long-term opioid use can cause opioid-induced hyperalgesia, which is a condition in which the patient has increased sensitivity ...
Pretreatment with MK-801 significantly reduced SP induced hyperalgesia. Intrathecal MK-801 also blocked hyperalgesia resulting ... Allodynia and hyperalgesia were experimentally induced by administration of CCK into the RVM. Spinal administration of SB- ... Behavioral hyperalgesia in inflammatory pain states is closely correlated with phosphorylation of spinal NMDA receptors. To ... Injection of the CCK-saporin conjugate also reversed allodynia and hyperalgesia in a nerve injury model, producing the same ...
"VICTORIAN HALLS Release Hyperalgesia". Mass Movement. 19 May 2015. Retrieved 22 June 2017. "VICTORIAN HALLS announce "All My ... Their second full-length studio album, "Hyperalgesia" was recorded in Gossip Studios, Chicago, and released in May 2015 with ... Hyperalgesia, while maintaining the overall characteristic experimental-rock feel of Victorian Halls' music, is a much more ...
It is different from hyperalgesia, an exaggerated response from a normally painful stimulus. The term comes from Ancient Greek ... Coutaux A, Adam F, Willer JC, Le Bars D (2005). "Hyperalgesia and allodynia: peripheral mechanisms". Joint Bone Spine. 72 (5): ...
Normally hyperalgesia ceases when inflammation goes down, however, sometimes genetic defects and/or repeated injury can result ... This is commonly known as hyperalgesia. Inflammation is one common cause that results in the sensitization of nociceptors. ...
This can cause allodynia or hyperalgesia. In individuals with chronic pain, EEGs showed altered brain activity, suggesting pain ... opioid-induced hyperalgesia, physical dependence, addiction, abuse, and overdose. Alternative medicine refers to health ...
Evidence for a link between PGE2 and hyperalgesia comes from an antisense deoxynucleotide knockdown of Nav1.8 in the DRG of ... Lai J, Porreca F, Hunter JC, Gold MS (2004). "Voltage-gated sodium channels and hyperalgesia". Annual Review of Pharmacology ... Therefore, Nav1.8 contributes to hyperalgesia (increased sensitivity to pain) and allodynia (pain from stimuli that do not ... hyperalgesia). The increased levels of nerve growth factor and tumour necrosis factor-α (TNF-α) causes the upregulation of ...
"Effects of Pregabalin on Mechanical Hyperalgesia". ClinicalTrials.gov. United States National Library of Medicine. 4 April 2007 ...
It has anti-hyperalgesia effects in animals. SIB-1757 along with other mGluR5 antagonists has been shown to have ...
His studies on the basic mechanisms involved in the development of inflammatory hyperalgesia led to the discovery that a select ... II-Prostaglandins hyperalgesia: the peripheral analgesic activity of morphine, enkephalins and opioid antagonists. ... Bradykinin initiates cytokine mediated inflammatory hyperalgesia. Brazilian Journal of Pharmacological Sciences. vol. 110, p. ... group made a relevant contribution to the role of bradykinin and of cytokines in the development of inflammatory hyperalgesia. ...
Sommer C, Schäfers M, Marziniak M, Toyka KV (June 2001). "Etanercept reduces hyperalgesia in experimental painful neuropathy". ...
People with this problem probably have hyperalgesia. The Fear of Pain Questionnaire (currently the FPQ-III), a mental health ...
Opioid-induced hyperalgesia Kraychete, DC; Sakata, RK (July 2012). "Use and rotation of opioids in chronic non-oncologic pain ...
Epub 2015 Mar 31.] The original Hp peptide reduces sensitivity to painful stimuli in an experimental model of hyperalgesia. Hp ... March 2005). "Antinociceptive action of hemopressin in experimental hyperalgesia". Peptides. 26 (3): 431-6. doi:10.1016/j. ...
DuPen A, Shen D, Ersek M (September 2007). "Mechanisms of opioid-induced tolerance and hyperalgesia". Pain Management Nursing. ...
Opioid-induced hyperalgesia is when exposure to opioids increases the sensation of pain (hyperalgesia) and can even make non- ... Opioid tolerance should not be confused with opioid-induced hyperalgesia. The symptoms of these two conditions can appear very ... Oxford University Press, 2004). Bannister K (June 2015). "Opioid-induced hyperalgesia: where are we now?". Current Opinion in ...
"CXCR4 signaling mediates morphine-induced tactile hyperalgesia". Brain, Behavior, and Immunity. 25 (3): 565-73. doi:10.1016/j. ... of CXCR4 signalling by plerixafor has also unexpectedly been found to be effective at counteracting opioid-induced hyperalgesia ...
DuPen A, Shen D, Ersek M (September 2007). "Mechanisms of opioid-induced tolerance and hyperalgesia". Pain Management Nursing. ...
These patient often have a lower pain threshold with balloon distension of the bowel (visceral hyperalgesia), or they have ... Narcotic bowel syndrome (NBS)/ Opioid-induced GI hyperalgesia E. Gallbladder and sphincter of Oddi disorders E1. Biliary pain ... Basic and clinical aspects of visceral hyperalgesia. Gastroenterology 1994;107:271-293 Zhou Q, Zhang B, Verne GE. Intestinal ...
It was developed as a potential analgesic, and blocks the development of hyperalgesia following exposure to cold temperatures ... Gong K, Jasmin L (February 2017). "Sustained Morphine Administration Induces TRPM8-Dependent Cold Hyperalgesia". The Journal of ...
Syriatowicz, J. P.; Hu, D.; Walker, J. S.; Tracey, D. J. (1999). "Hyperalgesia due to nerve injury: Role of prostaglandins". ... a compound that sensitizes neurons to mechanical stimuli and mechanical hyperalgesia) which further supports a role for HT ...
... hyperalgesia is believed to involve the activation of cholecystokinin receptors. Stewart-Williams and Podd argue that ... For example, precisely the same inert agents can produce analgesia and hyperalgesia, the first of which, from this definition, ... Verbal suggestion can cause hyperalgesia (increased sensitivity to pain) and allodynia (perception of a tactile stimulus as ... Colloca, Luana; Benedetti, Fabrizio (2007). "Nocebo hyperalgesia: How anxiety is turned into pain". Current Opinion in ...
Hyperalgesia is directly involved with spinal NMDA receptors. Administered NMDA antagonists in a clinical setting produce ...
"Opioid-Induced Hyperalgesia: How Opioids Can Increase Pain". Hospital for Special Surgery. Retrieved 5 September 2022. " ...
Nature (2008) 2002: Shin J et al., Bradykinin-12-lipoxygenase-VR1 signaling pathway for inflammatory hyperalgesia. Proc Natl ... 2002). "Bradykinin-12-lipoxygenase-VR1 signaling pathway for inflammatory hyperalgesia". Proc. Natl. Acad. Sci. USA. 99 (15): ...