Billingham RE (1966). "The biology of graft-versus-host reactions". Harvey Lectures. 62 (62): 21-78. PMID 4875305. Yasuda H, ... Hale G, Waldmann H (May 1994). "Control of graft-versus-host disease and graft rejection by T cell depletion of donor and ... A wide range of host antigens can initiate graft-versus-host disease, among them the human leukocyte antigens (HLA). However, ... Chronic graft-versus-host disease also attacks the above organs, but over its long-term course can also cause damage to the ...
Clark DA, Chaput A, Tutton D (March 1986). "Active suppression of host-vs-graft reaction in pregnant mice. VII. Spontaneous ... This is the same mechanism used by parasitic nematodes to avoid detection by the immune system of their host. There is presence ... Arora N, Sadovsky Y, Dermody TS, Coyne CB (May 2017). "Microbial Vertical Transmission during Human Pregnancy". Cell Host & ...
Clark DA, Chaput A, Tutton D (March 1986). "Active suppression of host-vs-graft reaction in pregnant mice. VII. Spontaneous ...
Clark DA, Chaput A, Tutton D (March 1986). "Active suppression of host-vs-graft reaction in pregnant mice. VII. Spontaneous ... This is the same mechanism used by parasitic nematodes to avoid detection by the immune system of their host. Also, there is ... Antinuclear antibodies cause an inflammation in the uterus that does not allow it to be a suitable host for implantation of the ...
Chronic graft-versus-host disease The history of preceding hematopoietic cell transplant is helpful for diagnosis Psoriasis ... Sometimes dental materials or certain medications can cause a lichenoid reaction. They can also occur in association with graft ... Vargas-Díez E, García-Díez A, Marín A, Fernández-Herrera J (May 2005). "Life-threatening graft-vs-host disease". Clinics in ... mainly Hypersensitivity reaction Restorative material (e.g. amalgam and composite) or drugs can cause hypersensitivity reaction ...
... is seen in graft-versus-host disease (GVHD) developed after a hematopoietic stem cell transplant (bone ... It is also a common manifestation of a skin reaction to the antibiotic amoxicillin or chemotherapy drugs. Cutaneous ... "Dermatologic Manifestations of Graft Versus Host Disease: Introduction, Clinical Overview, Pathophysiology". June 10, 2021 - ... List of cutaneous conditions "Allergic Reactions and Chemotherapy - Managing Side Effects - Chemocare". chemocare.com. " ...
"Pathogenesis of a local graft versus host reaction: immunogenicity of circulating host leukocytes". Science. 159 (3820): 1250-1 ... 210-1. ISBN 978-88-470-0374-3. Snell, George D. (1957). "The homograft reaction". Annual Review of Microbiology. 11: 439-58. ... by George Davis Snell and the term coined in 1968 when Elkins and Guttmann showed that leukocytes present in a donor graft ...
Savage WJ (June 2016). "Transfusion Reactions". Hematology/Oncology Clinics of North America. 30 (3): 619-634. doi:10.1016/j. ... Transfusion-associated graft-versus-host disease (TA-GvHD) is a rare complication of blood transfusion, in which the ... A Case of Fetal-Induced Graft-versus-Host Disease Fung MK, Grossman BJ, Hillyer CD, Westhoff CM (2014). Technical manual (18th ... Gupta A, Bansal D, Dass R, Das A (December 2004). "Transfusion associated graft versus host disease" (PDF). Indian Pediatrics. ...
Elkins, W.R., Guttmann, R.D.: Pathogenesis of a local graft versus host reaction. Immunogenicity of circulating host leucocytes ... Guttmann, R.D., Kraus, E.D., Dolan, M.F.: Rejection of isogeneic murine skin grafts following exposure to allogeneic ...
The most common adverse reactions include infections, graft-versus-host disease, and infusion reactions. Omidubicel is composed ...
Woodruff JM, Hansen JA, Good RA, Santos GW, Slavin RE (December 1976). "The pathology of the graft-versus-host reaction (GVHR) ... Upon histology, graft versus host disease may present with crypt cell necrosis and breakdown products within the crypts ... In patients who have undergone transplantation, graft versus host disease may also be a differential diagnosis. This response ...
Foundation Plant Services (FPS) offers testing via leaf graft. Hosts of Strawberry latent C virus include strawberry. ... virus is diagnosed by cross infection of one of the alternate hosts which are herbaceous or by polymerase chain reaction (PCR ... Tomato ringspot virus is diagnosed by cross infection of an herbaceous alternate host. Hosts include strawberry. Hosts of ... Hosts include strawberry. Pandemis pyrusana is present and eats the leaves of several crops. Hosts include strawberry. Clepsis ...
... graft versus host reaction, GVHR); rejection of H2-incompatible grafts (skin, heart, bone marrow, etc.) by the recipients; and ... Skin grafting and other methods indicated inbreeding within the demes, but sharing of certain alleles between the demes ... were also responsible for the rejection of incompatible grafts. Klein, with his coworker Vera Hauptfeld and his wife Dagmar ... The cells with receptors for self-molecules must be eliminated to prevent an immune reaction against the individual's own ...
His most important contribution to embryology was in his early investigation of the "graft-host" reaction. This seminal work ...
... a graft-versus-host reaction occurred; this was known as the Simonsen phenomenon. Their work in this system would later help to ... Burnet was involved in work relating to autoimmune diseases and the graft-versus-host reaction, and increasingly in theoretical ... Burnet's work on graft-versus-host was in collaboration with Lone Simonsen between 1960 and 1962. Simonsen had shown in 1957 ... He conducted research into the agglutinin reactions in typhoid fever, leading to his first scientific publications. He decided ...
In acute graft-versus-host disease, the most common hematologic adverse reactions include anemia, thrombocytopenia, and ... Ruxolitinib is also indicated for the treatment of steroid-refractory acute graft-versus-host disease in people who are twelve ... The indication was further expanded in the US in September 2021, for the treatment of chronic graft-versus-host disease (cGVHD ... In May 2019, the indication for ruxolitinib was expanded in the US to include steroid-refractory acute graft-versus-host ...
In addition, he foresaw the concept of graft-versus-host responses. Despite these research results, clinical application ... who also believed that immunological reactions explained graft rejection. Dempster and his associates demonstrated that ... irradiating the whole body could suppress delayed type hypersensitivity reactions and the response to skin allografts. This ...
Other side effects have included diarrhea, nosebleeds, sepsis, graft vs host disease, and pneumonia. Pregnant women should not ... There is a high risk of bleeding and some people have had hypersensitivity reactions to defibrotide. Common adverse effects, ... Some people have hypersensitivity reactions. Defibrotide was approved for medical use in the European Union in October 2013, in ... and allergic reactions. Defibrotide should not be used in people who are having bleeding complications or who are taking blood ...
One hypothesis is that these fetal cells might trigger a graft-versus-host reaction leading to autoimmune disease. This offers ... The fetal microchimerism may trigger a fetus versus host reaction and therefore may play a role in the pathogenesis of ... Two types of thyroid disease, Hashimoto's thyroiditis (HT) and Graves' disease (GD), show similarities to graft vs host disease ... or acuteness of bone marrow transplantation graft-versus-host disease is reduced, when recipients of donor stem cells are NIMA- ...
Penninger J, Hála K, Wick G. "Inrathymic nurse cell lymphocytes can induce a specific graft-versus-host reaction." J Exp Med ... Chicken TNC-T cells exhibit greater graft vs host reactivity than peripheral blood T cells or ET cells when TNCs from one ...
The success of a biomaterial relies on the host tissue's reaction with the foreign material. Specific reactions between the ... Graft-versus-host disease is an auto- and alloimmune disorder, exhibiting a variable clinical course. It can manifest in either ... Host response is defined as the "response of the host organism (local and systemic) to the implanted material or device". Most ... Velnar, Tomaz; Bunc, Gorazd; Klobucar, Robert; Gradisnik, Lidija (2016). "Biomaterials and host versus graft response: a short ...
Transfusion-associated graft versus host disease frequently occurs in immunodeficient patients where recipient's body failed to ... Febrile nonhemolytic reactions are, along with allergic transfusion reactions, the most common type of blood transfusion ... July 2015). "A systematic review of transfusion-associated graft-versus-host disease". Blood. 126 (3): 406-414. doi:10.1182/ ... However, this type of transfusion reaction is less severe when compared to acute haemolytic transfusion reaction. ...
... as a results of host-against-self reaction, where immune cells initiate tissue-specific destruction. Similarly, allografting ... results in a strong immune response, which clinically necessitates a continued immunosuppression to maintain graft survival. ... December 2018). "Cytolytic Activity (CYT) Score Is a Prognostic Biomarker Reflecting Host Immune Status in Hepatocellular ... proving the importance of immune reaction in breast cancer. It was also shown that ICR classification is dependent upon ...
GvL is a part of the reaction of the graft against the host. Whereas graft-versus-host-disease (GvHD) has a negative impact on ... Rezvani AR, Storb RF (May 2008). "Separation of graft-vs.-tumor effects from graft-vs.-host disease in allogeneic hematopoietic ... Warren EH, Deeg HJ (April 2013). "Dissecting graft-versus-leukemia from graft-versus-host-disease using novel strategies". ... CD73-generated adenosine limits the severity of graft vs. host disease but also constrains the allogeneic graft vs. tumor ...
... those at risk of transfusion-associated graft versus host disease). Fisk JM, Pisciotto PT, Snyder EL, Perrota PL (2007). " ... Side effects can include allergic reactions such as anaphylaxis, infection, and lung injury. Bacterial infections are ... Side effects can include allergic reactions such as anaphylaxis, infection, and lung injury. Bacterial infections are ... which decreases the risk of having a transfusion reaction. They can be treated with ultraviolet light which decreases the risk ...
Graft-versus-host disease (GVHD) is a major barrier for allogeneic stem cell transplant because of the immune reactions of ... Thus, cyclophosphamide preconditioning of recipient hosts (for donor T cells) has been used to enhance immunity in naïve hosts ... GVHD can often be avoided by T-cell depletion of the graft. The use of a high dose cyclophosphamide post-transplant in a half ... Adverse drug reactions from cyclophosphamide are related to the cumulative medication dose and include chemotherapy-induced ...
... and graft versus host disease. It was approved for medical use in the United States in October 2021. Allogeneic processed ... The most common adverse reactions include high blood pressure, cytokine release syndrome, low blood magnesium levels, rash, low ...
Bone marrow transplants require a complete match on six key antigens, which are measures of graft-versus-host reaction, known ... The high relapse rates after autologous or syngeneic transplant and the benefit of a graft-vs.-leukemia effect of an allogeneic ...
Graft formation improves the overall hydrophilicity of the material through a ratio of how much glycolic acid and lactic acid ... It is a requirement of biomaterials in which the surface modified material will cause no harm to the host, and the material ... It is described to be non-toxic, no induced adverse reactions such as chronic inflammatory response with unusual tissue ... Successful attempts at grafting biomolecules onto polymers have been made using photochemical modification of biomaterials. ...
If the donor white blood cells are not irradiated, the recipient may be at risk of developing graft-versus-host disease. ... which can predispose them to transfusion reactions, decrease the lifespan of donor white blood cells in their circulation, and ... which can cause graft-versus-host disease in the recipient, so it is often exposed to radiation to inactivate these cells.: 628 ... because antibodies against donor granulocytes can reduce the effectiveness of the transfusion and cause transfusion reactions ...