Humans and other animals must ingest histidine or histidine-containing proteins. The biosynthesis of histidine has been widely ... In a histidine proton shuttle, histidine is used to quickly shuttle protons. It can do this by abstracting a proton with its ... For histidine, for adults 19 years and older, 14 mg/kg body weight/day. Supplemental histidine is being investigated for use in ... Histidine forms complexes with many metal ions. The imidazole sidechain of the histidine residue commonly serves as a ligand in ...
In terms of enzymology, a histidine kinase (EC 2.7.13.3, EnvZ, histidine protein kinase, protein histidine kinase, protein ... protein L-histidine ⇌ {\displaystyle \rightleftharpoons } ADP + protein N-phospho-L-histidine. Thus, the two substrates of this ... the widespread existence of protein histidine phosphorylation distinct from that of two-component histidine kinases has been ... The histidine phosphorylation site is located at His-260. The N, G1, F and G2 boxes are contained in the C-terminal catalytic ...
In enzymology, a histidine transaminase (EC 2.6.1.38) is an enzyme that catalyzes the chemical reaction L-histidine + 2- ... Other names in common use include histidine aminotransferase, and histidine-2-oxoglutarate aminotransferase. This enzyme ... Wickremasinghe R, Hedegaard J, Roche J (1967). "Degradation de la L-histidine chez Escherichia coli B: formation de l'acide ... The systematic name of this enzyme class is L-histidine:2-oxoglutarate aminotransferase. ...
HDC decarboxylates histidine through the use of a PLP cofactor initially bound in a Schiff base to lysine 305. Histidine ... In humans, histidine decarboxylase is encoded by the HDC gene. Histidine decarboxylase is a group II pyridoxal-dependent ... "Entrez Gene: histidine decarboxylase". Riley WD, Snell EE (October 1968). "Histidine decarboxylase of Lactobacillus 30a. IV. ... HDC is highly specific for its histidine substrate. Histidine decarboxylase is the primary biological source of histamine. ...
... histidine):pyruvate aminotransferase, histidine:pyruvate aminotransferase, and L-phenylalanine(L-histidine):pyruvate ... In enzymology, a phenylalanine(histidine) transaminase (EC 2.6.1.58) is an enzyme that catalyzes the chemical reaction L- ... Minatogawa Y, Noguchi T, Kido R (January 1977). "Species distribution and properties of hepatic phenylalanine (histidine): ... Other names in common use include phenylalanine (histidine) aminotransferase, phenylalanine( ...
... may refer to: Histidine kinase, an enzyme Protein-histidine tele-kinase, an enzyme Protein-histidine ... pros-kinase, an enzyme This disambiguation page lists articles associated with the title Protein histidine kinase. If an ...
In enzymology, a histidine-tRNA ligase (EC 6.1.1.21) is an enzyme that catalyzes the chemical reaction ATP + L-histidine + ... This enzyme participates in histidine metabolism and aminoacyl-trna biosynthesis. Histidine-tRNA ligase belongs to the family ... The systematic name of this enzyme class is L-histidine:tRNAHis ligase (AMP-forming). Other names in common use include ... L-histidine, and tRNA(His), whereas its 3 products are AMP, diphosphate, and L-histidyl-tRNA(His). ...
N-acetyl-L-histidine Thus, the two substrates of this enzyme are acetyl-CoA and L-histidine, whereas its two products are CoA ... In enzymology, a histidine N-acetyltransferase (EC 2.3.1.33) is an enzyme that catalyzes the chemical reaction acetyl-CoA + L- ... The systematic name of this enzyme class is acetyl-CoA:L-histidine N-acetyltransferase. Other names in common use include ... Baslow MH (December 1966). "N -acetyl-L-histidine synthetase activity from the brain of the killifish". Brain Research. 3 (2): ...
... together with intensive buffering of the extracellular space by means of histidine/histidine hydrochloride, so as to prolong ... Histidine-tryptophan-ketoglutarate, or Custodiol HTK solution, is a high-flow, low-potassium preservation solution used for ... Finally, histidine is thought to aid buffering, mannitol and tryptophan to improve membrane stability, and ketoglutarate to ... 4. Pokorny H., et al.: Histidine-tryptophan-ketoglutarate solution for organ preservation in human liver transplantation - a ...
a EINECS number 200-745-3 (D-histidine) ^a EINECS number 206-513-8 (L-histidine) ^a CID 71083 from PubChem (D-histidine) ^a CID ... 6274 from PubChem (L-histidine) (Articles with short description, Short description matches Wikidata, PubChem ID (CID) not in ...
It converts histidine into ammonia and urocanic acid. Its systematic name is L-histidine ammonia-lyase (urocanate-forming). ... Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative ... Histidine ammonia-lyase (EC 4.3.1.3, histidase, histidinase) is an enzyme that in humans is encoded by the HAL gene. ... "Entrez Gene: histidine ammonia-lyase". Suchi M, Sano H, Mizuno H, Wada Y (September 1995). "Molecular cloning and structural ...
... (HME) is an irreversible histidine decarboxylase inhibitor. It is the methyl ester of histidine. ... Histidine decarboxylase Alpha-Fluoromethylhistidine Lane, Roger S; Manning, James M; Snell, Esmond E (2002). "Histidine ... Alston, Theodore A; Abeles, Robert H (2002). "Reaction of Lactobacillus histidine decarboxylase with L-histidine methyl ester ... Histidine decarboxylase inhibitors, Amino acid derivatives, Imidazoles, Methyl esters, Carboxylate esters, All stub articles, ...
... s and histidine phosphotransferases (both often abbreviated HPt) are protein domains involved ... In orthodox two-component signaling, a histidine kinase protein autophosphorylates on a histidine residue in response to an ... with similarity to the structure of histidine kinases. Monomeric HPt domains possess only one phosphorylatable histidine ... In some cases, a phosphorelay system is constructed from four separate proteins rather than a hybrid histidine kinase with an ...
The Histidine operon leader is an RNA element found in the bacterial histidine operon. At least 6 amino acid operons are known ... Page for Histidine operon leader at Rfam v t e (Cis-regulatory RNA elements, All stub articles, Molecular and cellular biology ...
"Entrez Gene: HRG histidine-rich glycoprotein". Wakabayashi S (2013). New insights into the functions of histidine-rich ... The high concentration of both histidine and proline residues has resulted in HRG also being termed 'histidine-proline-rich ... Histidine-rich glycoprotein (HRG) is a glycoprotein that in humans is encoded by the HRG gene. The HRG protein is produced in ... This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. It is known that ...
... histidine kinase, histidine protein kinase, protein histidine kinase, protein kinase (histidine), and HK3. Fujitaki JM, Fung G ... protein-histidine kinases). The systematic name of this enzyme class is ATP:protein-L-histidine Ntau-phosphotransferase. Other ... protein L-histidine ⇌ {\displaystyle \rightleftharpoons } ADP + protein Nτ-phospho-L-histidine Thus, the two substrates of this ... In enzymology, a protein-histidine tele-kinase (EC 2.7.13.2) is an enzyme that catalyzes the chemical reaction ATP + ...
... (FruHis) is a ketosamine combining the d-isomer of fructose and the l-isomer of histidine into a ... Valeri V. Mossine and Thomas P. Mawhinney (2007). "Nα-(1-Deoxy-D-fructos-1-yl)-L-histidine ("D-Fructose-L-histidine"): a Potent ...
Other names in common use include protein methylase IV, protein (histidine) methyltransferase, actin-specific histidine ... protein L-histidine ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + protein Ntau-methyl-L-histidine Thus, the ... In enzymology, a protein-histidine N-methyltransferase (EC 2.1.1.85) is an enzyme that catalyzes the chemical reaction S- ... The systematic name of this enzyme class is S-adenosyl-L-methionine:protein-L-histidine N-tele-methyltransferase. ...
... histidine kinase, histidine protein kinase, protein histidine kinase, protein kinase (histidine), and HK2. Fujitaki JM, Fung G ... protein-histidine kinases). The systematic name of this enzyme class is ATP:protein-L-histidine Npi-phosphotransferase. Other ... protein L-histidine ⇌ {\displaystyle \rightleftharpoons } ADP + protein Nπ-phospho-L-histidine Thus, the two substrates of this ... In enzymology, a protein-histidine pros-kinase (EC 2.7.13.1) is an enzyme that catalyzes the chemical reaction ATP + ...
Like nucleotides, biosynthesis of histidine is initiated by the conversion of R5P to PRPP. The step of histidine biosynthesis ... Histidine biosynthesis is carefully regulated by feedback inhibition/ R5P can be converted to adenosine diphosphate ribose, ... cite book}}: ,journal= ignored (help) Ingle RA (January 2011). "Histidine biosynthesis". The Arabidopsis Book. 9: e0141. doi: ... and histidine. Nucleotides serve as the building blocks for nucleic acids, DNA and RNA. They are composed of a nitrogenous base ...
Examples include cystine from hydrolysis of hair, tryptophane from casein, histidine from red blood cells, and arginine from ... Foster, G. L.; Shemin, D. (1938). "L-Histidine Monohydrochloride". Organic Syntheses. 18: 43. doi:10.15227/orgsyn.018.0043. ...
3-Methyl-L-histidine. 23 December 2017. Retrieved 25 December 2017. {{cite encyclopedia}}: ,work= ignored (help) Chinkes DL ( ... 3-Methylhistidine is a metabolic product that is produced in the body via the enzymatic methylation of histidine during peptide ...
This enzyme participates in histidine metabolism as it is involved in the 6th step of histidine biosynthesis as part of a nine ... AMES BN (1957). "The biosynthesis of histidine; D-erythro-imidazoleglycerol phosphate dehydrase". J. Biol. Chem. 228 (1): 131- ... "Structure and function of the Salmonella typhimurium and Escherichia coli K-12 histidine operons". J. Mol. Biol. 203 (3): 585- ...
There are also protein kinases that phosphorylate other amino acids, including histidine kinases that phosphorylate histidine ... Histidine kinases are structurally distinct from most other protein kinases and are found mostly in prokaryotes as part of two- ... Histidine kinases are found widely in prokaryotes, as well as in plants, fungi and eukaryotes. The pyruvate dehydrogenase ... A phosphate group from ATP is first added to a histidine residue within the kinase, and later transferred to an aspartate ...
Ames BN (June 1957). "The biosynthesis of histidine; L-histidinol phosphate phosphatase". The Journal of Biological Chemistry. ... phosphate This enzyme participates in histidine metabolism. This enzyme belongs to the family of hydrolases, to be specific, ...
Carbon atoms from ribose in PRPP form the linear chain and part of the imidazole ring in histidine. The same is true for the ... The histidine biosynthesis pathway involves the reaction between PRPP and ATP, which activates the latter to ring cleavage. ... Stepansky, A.; Leustek, T. (2006). "Histidine biosynthesis in plants". Amino Acids. 30 (2): 127-142. doi:10.1007/s00726-005- ... L-histidine biosynthesis". MetaCyc Metabolic Pathway Database. Retrieved 2022-02-17. ...
It is a secondary disorder of histidine metabolism. Urocanic aciduria is thought to be relatively benign. Although aggressive ... The amino acid histidine, when catalyzed by the enzyme histidase, forms urocanic acid. Disruptions in this pathway, caused by a ... With normal to only slightly elevated levels of histidine present in the liver during urocanic aciduria, the only true ... Disorders of histidine metabolism. http://www.ommbid.com/OMMBID/the_online_metabolic_and_molecular_bases_of_inherited_disease/b ...
Phosphorylation usually occurs on serine, threonine, tyrosine and histidine residues in eukaryotic proteins. Histidine ... Histidine and aspartate phosphorylation occurs in prokaryotes as part of two-component signaling and in some cases in ... Once histidine is phosphorylated the regulatory domain of the response regulator catalyzes the transfer of the phosphate to ... and In prokaryotes, archea, and some lower eukaryotes histidine's nitrogen act as a nucleophile and binds to a phosphate group ...
Lysine, Histidine, Arginine, and Valine". Proceedings of the Society for Experimental Biology and Medicine. 61 (2): 158-161. ... Rosenthaler, J.; Guirard, B. M.; Chang, G. W.; Snell, E. E. (1965-07-01). "Purification and properties of histidine ... Guirard, B M; Tanase, S; Snell, E E (1984-01-01). "Pyridoxal-P dependent bacterial histidine decarboxylase". Progress in ... Rosenthaler, J.; Guirard, B. M.; Chang, G. W.; Snell, E. E. (1965-07-01). "Purification and properties of histidine ...
Rose's later work showed that eight amino acids are essential for adult human beings, with histidine also being essential for ... Kopple JD, Swendseid ME (May 1975). "Evidence that histidine is an essential amino acid in normal and chronically uremic man". ... Of the twenty amino acids common to all life forms (not counting selenocysteine), humans cannot synthesize nine: histidine, ... The role of threonine and histidine". The Journal of Biological Chemistry. 188 (1): 49-58. doi:10.1016/S0021-9258(18)56144-5. ...