Human herpesvirus 6
... (HHV-6) is the common collective name for human betaherpesvirus 6A (HHV-6A) and human betaherpesvirus 6B ( ... Media related to Human herpesvirus 6 at Wikimedia Commons Data related to Human herpesvirus 6 at Wikispecies (CS1 French- ... Human herpesvirus 6 lives primarily on humans and, while variants of the virus can cause mild to fatal illnesses, can live ... Shiley, Kevin; Blumberg, Emily (2010). "Herpes Viruses in Transplant Recipients: HSV, VZV, Human Herpes Viruses, and EBV". ...
Kaposi's sarcoma-associated herpesvirus
... (KSHV) is the ninth known human herpesvirus; its formal name according to the ... Mesri, Enrique A.; Cesarman, Ethel; Boshoff, Chris (October 2010). "Kaposi's sarcoma herpesvirus/ Human herpesvirus-8 (KSHV/ ... Schulz, T. F. (2000). "Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8): Epidemiology and pathogenesis". The ... Wikispecies has information related to Kaposi's sarcoma-associated herpesvirus. Human Herpesvirus-8: Related Resources HIV ...
Oncolytic herpes virus
NV1020 is an oncolytic herpes virus initially developed by Medigene Inc. and licensed for development by Catherex Inc. in 2010 ... Human Gene Therapy. 23 (1): 91-7. doi:10.1089/hum.2011.141. PMID 21895536. "Amgen, Form 8-K, Current Report, Filing Date Jan 26 ... Mohr I, Gluzman Y (September 1996). "A herpesvirus genetic element which affects translation in the absence of the viral GADD34 ... Human Gene Therapy. 21 (9): 1119-28. doi:10.1089/hum.2010.020. PMC 3733135. PMID 20486770. Clinical trial number NCT00149396 ...
Herpes simplex virus
The only human vaccines available for herpesviruses are for Varicella zoster virus, given to children around their first ... also known by their taxonomic names Human alphaherpesvirus 1 and Human alphaherpesvirus 2, are two members of the human ... Animal herpes viruses all share some common properties. The structure of herpes viruses consists of a relatively large, double- ... Davidson AJ (2007-08-16). "Comparative analysis of the genomes". Human Herpesviruses. Cambridge University Press. ISBN 978-0- ...
HHV-8-associated MCD
Human herpesvirus 8 associated multicentric Castleman disease (HHV-8-associated MCD) is a subtype of Castleman disease (also ... People with human herpesvirus 8 associated multicentric Castleman disease (HHV-8-associated MCD) have enlarged lymph nodes in ... Dossier A, Meignin V, Fieschi C, Boutboul D, Oksenhendler E, Galicier L (March 2013). "Human herpesvirus 8-related Castleman ... Castleman disease describes a group of at least three distinct disorders-unicentric Castleman disease (UCD), human herpesvirus ...
Infectious causes of cancer
Two types of herpesviruses have been associated with cancer: the Epstein-Barr virus (EBV) and human herpesvirus 8 (HHV-8). EBV ... Herpesviruses also cause cancer in animals, especially leukemias and lymphomas. Human T cell lymphotropic virus (HTLV-1) was ... Kaposi's sarcoma is caused by human herpesvirus 8. AIDS-related cases of anal cancer and cervical cancer are commonly caused by ... "Human Papillomavirus (HPV) and Cancer , CDC". 2019-08-21. Münger K, Baldwin A, Edwards KM, Hayakawa H, Nguyen CL, Owens M, et ...
Kaposi's sarcoma
Ablashi DV, Chatlynne LG, Whitman JE, Cesarman E (July 2002). "Spectrum of Kaposi's sarcoma-associated herpesvirus, or human ... "Mucosal shedding of human herpesvirus 8 in men". The New England Journal of Medicine. 343 (19): 1369-77. doi:10.1056/ ... "Transmission of human herpesvirus 8 by blood transfusion". The New England Journal of Medicine. 355 (13): 1331-8. doi:10.1056/ ... and infection by Human herpesvirus 8 (HHV8 - also called KS-associated herpesvirus (KSHV)). Classic, endemic, immunosuppression ...
CD46
The encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6 (HHV-6), group B ... Mori (2009). "Recent topics related to human herpesvirus 6 cell tropism". Cellular Microbiology. 11 (7): 1001-6. doi:10.1111/j. ... Arbuckle, Jesse (2011). "The molecular biology of human herpesvirus-6 latency and telomere integration". Microbes and Infection ... Taylor CT, Biljan MM, Kingsland CR, Johnson PM (May 1994). "Inhibition of human spermatozoon-oocyte interaction in vitro by ...
Pityriasis rosea
While the cause is not entirely clear, it is believed to be related to human herpesvirus 6 (HHV6) or human herpesvirus 7 (HHV7 ... "Evidence of human herpesvirus-6 and -7 reactivation in miscarrying women with pityriasis rosea". Journal of the American ... "Pityriasis rosea is not associated with human herpesvirus 7". Archives of Dermatology. 135 (9): 1070-2. doi:10.1001/archderm. ... Some believe it to be a reactivation of herpes viruses 6 and 7, which cause roseola in infants, though some investigations have ...
Large B-cell lymphoma arising in HHV8-associated multicentric Castleman's disease
Cesarman E, Knowles DM (1997). "Kaposi's sarcoma-associated herpesvirus: a lymphotropic human herpesvirus associated with ... Human herpesvirus 8 (HHV-8), also known as Kaposi sarcoma-associated herpesvirus (KSHV) has been found in some cases of ... Malnati MS, Dagna L, Ponzoni M, Lusso P (2003). "Human herpesvirus 8 (HHV-8/KSHV) and hematologic malignancies". Rev Clin Exp ... 2014). "Unique expression pattern of viral proteins in human herpesvirus 8-positive plasmablastic lymphoma: a case report". Int ...
Gabriella Campadelli-Fiume
As the author of an overall encyclopedic of basic virology and clinical manifestations, Human Herpesviruses, her work has been ... 2007). Human herpesviruses : biology, therapy and immunoprophylaxis. Cambridge: Cambridge University Press. ISBN 978-0-511- ... The Egress of Herpesviruses from Cells: the Unanswered Questions De Castro Barbosa F, Agüera L, Rosell D, Isa W, Sánchez de la ... Gabriella Campadelli-Fiume took part in a study showing that glycoproteins gD, gB, and gH/gL permit herpes virus to enter cells ...
Chickenpox
eds.). Human herpesviruses : biology, therapy, and immunoprophylaxis. Cambridge: Cambridge University Press. ISBN 978-0-521- ... Chickenpox is an airborne disease which easily spreads via human-to-human transmission, typically through the coughs and ... Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis, Cambridge: Cambridge University Press, ISBN 978-0-521-82714-0, ... Humans are the only known species that the disease affects naturally. However, chickenpox has been caused in other primates, ...
Cervical cancer
Human papillomavirus infection (HPV) causes more than 90% of cases; most who have had HPV infections, however, do not develop ... Herpes viruses were also implicated in other malignant diseases, including Burkitt's lymphoma, Nasopharyngeal carcinoma, ... Tiro JA, Meissner HI, Kobrin S, Chollette V (February 2007). "What do women in the U.S. know about human papillomavirus and ... "Human Papillomavirus (HPV) Vaccines". National Cancer Institute. 29 December 2011. Archived from the original on 4 July 2014. ...
Infections associated with diseases
Di Luca, D; Zorzenon, M; Mirandola, P; Colle, R; Botta, GA; Cassai, E (1995). "Human herpesvirus 6 and human herpesvirus 7 in ... JC Virus and Simian Virus 40 Infection in Humans, and Association with Human Tumors". Polyomaviruses and Human Diseases. ... 2007). "Association of Human Herpesvirus-6B with Mesial Temporal Lobe Epilepsy". PLOS Medicine. 4 (5): e180. doi:10.1371/ ... Chapenko, S; Krumina, A; Kozireva, S; Nora, Z; Sultanova, A; Viksna, L; Murovska, M (2006). "Activation of human herpesviruses ...
Roseola
There are nine known human herpesviruses. Of these, roseola has been linked to two: human herpesvirus 6 (HHV-6) and human ... It is caused by human herpesvirus 6 (HHV-6A, HHV-6B) or human herpesvirus 7 (HHV-7). Spread is usually through the saliva of ... "Contributions of neurotropic human herpesviruses herpes simplex virus 1 and human herpesvirus 6 to neurodegenerative disease ... Between the two types of human herpesvirus 6, HHV-6B has been detected much more frequently in hosts. HHV-6B has been shown to ...
Interferon regulatory factors
Offermann MK (2007). "Kaposi sarcoma herpesvirus-encoded interferon regulator factors". Kaposi Sarcoma Herpesvirus: New ... Weisz A, Marx P, Sharf R, Appella E, Driggers PH, Ozato K, Levi BZ (December 1992). "Human interferon consensus sequence ... The Kaposi sarcoma herpesvirus, KSHV, is a cancer virus that encodes four different IRF-like genes; including vIRF1, which is a ... Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, Knowles DM, Moore PS (December 1994). "Identification of herpesvirus-like ...
Teething
Herpes virus infection may take the form of primary herpetic gingivostomatitis (HSV-1) or of infection by human herpesvirus 6 ( ... 2005). "A Population-Based Study of Primary Human Herpesvirus 6 Infection". New England Journal of Medicine. 352 (8): 768-76. ... such as a herpes virus, initial infection of which is extremely widespread among children of teething age. The level of pain ... particularly infection by herpes viruses. "Coincidentally, primary tooth eruption begins at about the time that infants are ...
Histone deacetylase
This has been shown to occur, for instance, with a latent human herpesvirus-6 infection. Histone deacetylase inhibitors have ... Arbuckle JH, Medveczky PG (August 2011). "The molecular biology of human herpesvirus-6 latency and telomere integration". ... Bhakat KK, Izumi T, Yang SH, Hazra TK, Mitra S (December 2003). "Role of acetylated human AP-endonuclease (APE1/Ref-1) in ... September 2008). "Structural and functional analysis of the human HDAC4 catalytic domain reveals a regulatory structural zinc- ...
Rolling circle replication
For instance, human herpesvirus-6 (HHV-6)(hibv) expresses a set of "early genes" that are believed to be involved in this ... Borenstein, Ronen; Frenkel, Niza (2009). "Cloning human herpes virus 6A genome into bacterial artificial chromosomes and study ... Arbuckle, Jesse (2011). "The molecular biology of human herpesvirus-6 latency and telomere integration". Microbes and Infection ... Human Papillomavirus-16 (HPV-16) is another virus that employs rolling replication to produce progeny at a high rate. HPV-16 ...
Duesberg hypothesis
Kedes D, Operskalski E, Busch M, Kohn R, Flood J, Ganem D (1996). "The seroepidemiology of human herpesvirus 8 (Kaposi's ... "Sexual transmission and the natural history of human herpesvirus 8 infection". N Engl J Med. 338 (14): 948-54. doi:10.1056/ ... Duesberg P (1989). "Human immunodeficiency virus and acquired immunodeficiency syndrome: correlation but not causation". Proc ... Duesberg rejects a role in cancer for numerous viruses, including leukemia viruses, Epstein-Barr virus, human papilloma virus, ...
HPV-positive oropharyngeal cancer
Human herpesvirus-8 infection can potentiate the effects of HPV-16. Risk factors include a high number of sexual partners (25% ... IARC Working Group on the Evaluation of Carcinogenic Risks to Humans (2007). "Human papillomaviruses". IARC Monographs on the ... IARC Working Group on the Evaluation of Carcinogenic Risks to Humans (2012). "Human Papilloviruses". Biological Agents. pp. 255 ... "Human papillomaviruses". IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. 64: 1-378. PMC 5366848. PMID ...
Dean H. Kedes
Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture. Nature Medicine. 1996;2(3):342-346. ... Kedes DH, Operskalski E, Busch M, Kohn R, Flood J, Ganem D. The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma- ... Sexual Transmission and the Natural History of Human Herpesvirus 8 Infection. New England Journal of Medicine. 1998;338(14):948 ... "Researchers Find a Herpes Virus That Has a Role in an AIDS-Related Cancer". Howard Hughes Medical Institute. March 1, 1996. " ...
Concatemer
In the case of human herpesvirus-6, its entire genome is made over and over on a single strand. These long concatemers are ... Borenstein, Ronen; Frenkel, Niza (2009). "Cloning human herpes virus 6A genome into bacterial artificial chromosomes and study ... Arbuckle, Jesse (2011). "The molecular biology of human herpesvirus-6 latency and telomere integration". Microbes and Infection ... 13 (8-9): 731-741. doi:10.1016/j.micinf.2011.03.006. PMC 3130849. PMID 21458587. Bernstein H, Bernstein C (July 1973). " ...
Virus
Kaposi's sarcoma-associated herpesvirus and human T-lymphotropic virus. The most recently discovered human cancer virus is a ... Jordan MC, Jordan GW, Stevens JG, Miller G (June 1984). "Latent herpesviruses of humans". Annals of Internal Medicine. 100 (6 ... ISBN 978-0-7817-8215-9. Komaroff AL (December 2006). "Is human herpesvirus-6 a trigger for chronic fatigue syndrome?". Journal ... Infection by human T-lymphotropic virus can lead to tropical spastic paraparesis and adult T-cell leukaemia. Human ...
Homologous recombination
... is the proposed mechanism whereby the DNA virus human herpesvirus-6 integrates into human telomeres. ... isogenic human disease models. These engineered human cell models are thought to more accurately reflect the genetics of human ... Arbuckle JH, Medveczky PG (August 2011). "The molecular biology of human herpesvirus-6 latency and telomere integration". ... Muntoni A, Reddel RR (October 2005). "The first molecular details of ALT in human tumor cells". Human Molecular Genetics. 14 ...
LL-100 panel
"Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture". Nature Medicine. 2 (3): 342-6. doi: ... "M-07e human leukemic factor-dependent cell line provides a rapid and sensitive bioassay for the human cytokines GM-CSF and IL-3 ... NCI-60, 60 human cancer cell lines used by the NCI List of breast cancer cell lines Quentmeier, H; Pommerenke, C; Dirks, WG; ... The LL-100 panel is a group of 100 human leukemia and lymphoma cell line, can be used in model of biomedical research. LL-100 ...
Interleukin
IL-10 is highly similar to the Human herpesvirus 4 (Epstein-Barr virus) BCRF1 protein, which inhibits the synthesis of gamma- ... interferon and to Equid herpesvirus 2 (Equine herpesvirus 2) protein E7. It is also similar, but to a lesser degree, with human ... "Role of IL-15 on monocytic resistance to human herpesvirus 6 infection". The New Microbiologica. 23 (2): 105-12. PMID 10872679 ... "Disulfide structures of human interleukin-6 are similar to those of human granulocyte colony stimulating factor". Archives of ...
Stuart C. Sealfon
"The human herpesvirus 8 chemokine receptor vGPCR triggers autonomous proliferation of endothelial cells". J Clin Invest. 116 (5 ... Through the Sealfon Laboratory and The Mount Sinai Medical Center, he oversees research on human hallucinogenic drugs of abuse ... "Chromosome-specific and noisy IFNB1 transcription in individual virus-infected human primary dendritic cells". Nucleic Acids ...
Plasmablastic lymphoma
Unlike PBL, the plasmablastic cells in human herpesvirus 8-positive diffuse large B-cell lymphoma, not otherwise specified ... and human herpesvirus 8-positive diffuse large B-cell lymphoma, not otherwise specified. All of these lymphomas are ... primary effusion lymphoma that is Kaposi's sarcoma-associated herpesvirus positive or Kaposi's sarcoma-associated Herpesvirus ... Rezk SA, Zhao X, Weiss LM (June 2018). "Epstein-Barr virus-associated lymphoid proliferations, a 2018 update". Human Pathology ...
CD200R1
"Down-regulation of basophil function by human CD200 and human herpesvirus-8 CD200". Journal of Immunology. 175 (7): 4441-9. doi ... Foster-Cuevas M, Wright GJ, Puklavec MJ, Brown MH, Barclay AN (July 2004). "Human herpesvirus 8 K14 protein mimics CD200 in ... CD200R1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Human CD200R1 genome location ... Human HCRTR2 genome location and HCRTR2 gene details page in the UCSC Genome Browser. This article incorporates text from the ...