Human T-lymphotropic virus (HTLV) causes T cell leukemias. Hepatitis B (HBV) and C (HCV) viruses cause chronic inflammation ... In some patients, the majority of the tumor-specific T cells recognize mutated antigens. The contribution of these antigens to ... The carcinoma cells still harbour the viral genes and antigens. As expected T cell responses against antigens encoded by genes ... Cancer therapy targeted at tumor antigens can involve the direct use of these antigens in vaccines, but also the adoptive ...

"Antibodies to HTLV-III associated antigens in populations exposed to AIDS virus in France". Lancet. 2 (8400): 460. doi:10.1016/ ... HTLV induces the massive proliferation of one or several clones and their cancerization, whereas the other virus, the HIV virus ... For his part, Willy Rozenbaum, warned in private by Leibowitch that an exotic HTLV-type retrovirus could well be the cause of ... The Montagnier team subsequently detected in the cell culture of patient BRU the traces of the first non HTLV retrovirus in ...

HTLV-I) or related antigens in lymphomatous and healthy hamadryas baboons". International Journal of Cancer. 36 (5): 579-84. ... antigens in pre-lymphomatous baboons (Papio hamadryas) of the Sukhumi high lymphoma stock". International Journal of Cancer. 32 ... most notably on the identification of the Middle Eastern lineage of human retrovirus HTLV-1, genetic resistance to HIV/AIDS and ...

... an indigenous population carrying HTLV-I in Sakhalin, Far Eastern Russia". Tissue Antigens. 52 (5): 444-51. doi:10.1111/j.1399- ... HLA-DQ8 (DQ8) is a human leukocyte antigen serotype within the HLA-DQ (DQ) serotype group. DQ8 is a split antigen of the DQ3 ... These split antigens are the allele products of the DQB1*0302 and DQB1*0305, respectively. DQB1*0302 and is found most often in ... and 2.Zhou L, Lin B, Xie Y, Liu Z, Yan W, Xu A (2005). "Polymorphism of human leukocyte antigen-DRB1, -DQB1, and -DPB1 genes of ...

1992). "HLA antigens in Tlingit Indians with rheumatoid arthritis". Tissue Antigens. 40 (2): 57-63. doi:10.1111/j.1399- ... 1998). "HLA class I and class II of the Nivkhi, an indigenous population carrying HTLV-I in Sakhalin, Far Eastern Russia". ... HLA-A9 (A9) is a broad antigen HLA-A serotype that recognized the HLA-A23 and HLA-A24 serotypes. A*2402 appears to have evolved ... Fussell H, Thomas M, Street J, Darke C (1996). "HLA-A9 antibodies and epitopes". Tissue Antigens. 47 (4): 307-12. doi:10.1111/j ...

HTLV-1)-associated myelopathy/tropical spastic paraparesis between Iranian and Japanese HTLV-1-infected individuals". J Gen ... "HLA-DR antigens in rheumatoid arthritis. A Swiss collaborative study; final report. Swiss Federal Commission for the Rheumatic ... In lyme disease arthritis, *01:01 appears to play a role in presentation of triggering microbial antigens. DRB1*01:02 is ... "HLA antigens and seronegative rheumatoid arthritis". Ann Rheum Dis. 44 (1): 50-53. doi:10.1136/ard.44.1.50. PMC 1001567. PMID ...

... transplantation antigens, trypanosoma, cancer, HPV, tuberculosis, chlamydia, HTLV, vaccinia, CMV, influenza, VSV, EBV, LCMV, ... 2001). "Antigen-specific modulation of an immune response by in vivo administration of soluble MHC class I tetramers". J. ... MHC pentamers have been used in the detection of antigen-specific CD8+ T cells in flow cytometry, and are cited in over 750 ... MHC multimers allow for ex vivo selection and proliferation of T-cells specific to viral or tumor-related antigens, which can ...

... antigen, b-cell MeSH D12.776.377.715.548.950.500 - antigens, cd79 MeSH D12.776.377.715.647.100 - alpha-macroglobulins See List ... htlv-i antibodies MeSH D12.776.377.715.548.114.254.150.510 - htlv-ii antibodies MeSH D12.776.377.715.548.114.254.450 - ... antigen-antibody complex MeSH D12.776.377.715.548.114.301 - antitoxins MeSH D12.776.377.715.548.114.301.138 - antivenins MeSH ... antigens, polyomavirus transforming MeSH D12.776.624.664.520.420 - papillomavirus e7 proteins MeSH D12.776.624.664.520.750 - ...

... antigen, b-cell MeSH D12.776.124.486.485.950.500 - antigens, cd79 MeSH D12.776.124.790.106.050 - alpha 1-antichymotrypsin MeSH ... htlv-i antibodies MeSH D12.776.124.486.485.114.254.150.510 - htlv-ii antibodies MeSH D12.776.124.486.485.114.254.450 - ... htlv-i antibodies MeSH D12.776.124.790.651.114.254.150.510 - htlv-ii antibodies MeSH D12.776.124.790.651.114.254.450 - ... antigens, cd46 MeSH D12.776.124.486.274.920.250 - complement c1 inactivator proteins MeSH D12.776.124.486.274.920.250.500 - ...

They also are among the first to suspect a relationship between the retrovirus that causes human T-cell leukemia (HTLV-1) and ... which enables the immune system to recognize antigens. 1982: Dana-Farber researchers develop and apply the CA-125 blood test ...

2002). "HTLV-1 Tax-associated hTid-1, a human DnaJ protein, is a repressor of Ikappa B kinase beta subunit". J. Biol. Chem. 277 ... 2002). "Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies". J. Immunol. 169 (2 ...

There have been a handful of IBM cases - approximately 15 - that have shown clear evidence of a virus called HTLV-1. The HTLV-1 ... These T cells appear to be driven by specific antigens to invade muscle fibers. In people with sIBM, the muscle cells display " ... Some 67% of IBM patients have a particular combination of human leukocyte antigen genes in a section of the 8.1 ancestral ... The chronic stimulation of these antigens also causes stress inside the muscle cell in the endoplasmic reticulum (ER) and this ...

This virus turned out to be HTLV-1 and the research established the causal role of the HTLV-1 virus to ATL. Between 1984 and ... In SV40, the large T antigen (LT) is an analogue; LT also binds to several other cellular proteins, such as p107 and p130, on ... Gallo RC (September 2005). "History of the discoveries of the first human retroviruses: HTLV-1 and HTLV-2". Oncogene. 24 (39): ... Because foreign virus antigens are expressed in these tumors, persons who are immunosuppressed such as AIDS or transplant ...

... response against the HTLV-1 Tax antigen. A vaccine candidate that can elicit or boost anti-gp46 neutralizing antibody response ... Mahieux, R; Gessain, A (2005). "Les nouveaux rétrovirus humains HTLV-3 et HTLV-4" [New human retroviruses: HTLV-3 and HTLV-4] ( ... HTLV-1 and HTLV-2 are both involved in actively spreading epidemics, affecting 15-20 million people worldwide. HTLV-1 is the ... Mahieux, R.; Gessain, Antoine (2009). "The human HTLV-3 and HTLV-4 retroviruses: New members of the HTLV family". Pathologie ...

Fisher was educated at the University of Birmingham where she was awarded a PhD in 1984 for research into antigens expressed ... HTLV). At the NIH, Fisher developed approaches that allowed the successful introduction of exogenous DNA onto human blood cells ... Epigenetic reprogramming by Amanda Fisher on Vimeo Fisher, Amanda Gay (1984). Surface antigens expressed during myelopoiesis. ... "A rapid method for determining whether monoclonal antibodies react with the same or different antigens on the cell surface". ...

HTLV-1). Dr. Waldmann demonstrated that the HTLV-1 encoded protein Tax constitutively activates two autocrine (IL-2R/IL-2, IL- ... He demonstrated that it is bound to IL-15 R alpha on the surface of antigen presenting cells and presented in trans to T-cells ... "Immunoglobulin gene rearrangement and cell surface antigen expression of acute lymphocyte leukemias of T-cell and B-cell ... HTLV-I associated adult T-cell leukemia (ATL). In the early 80s Waldmann studied immunoglobulin gene rearrangement in and cell ...

A26 is a split antigen of the broad antigen serotype A10. A26 is a sister serotype of A25, A34, A43, and A66. A26 is more ... the limited recognition of HTLV type 1 tax peptide anchor motifs and epitopes to generate anti-HTLV type 1 tax CD8(+) cytotoxic ... Arce-Gomez B, Jones EA, Barnstable CJ, Solomon E, Bodmer WF (February 1978). "The genetic control of HLA-A and B antigens in ... HLA-A26 (A26) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody ...

Antigen-presenting cells (APC) are capable of internalizing pathogens and displaying a fragment of the antigen - the epitope - ... CMV infection provoked a unique interferon response whereas HTLV-1 infection induced NF-kB target genes. A type of white blood ... Antibody microarrays use antibodies as probes and antigens as targets. They can be used to directly measure the antigen ... Peptide microarrays use antigen peptides as probes and serum antibodies as targets. These can be used for functional immunomic ...

Chang TW, Kung PC, Gingras SP, and Goldstein G, 1981, "Does OKT3 monoclonal antibody react with an antigen-recognition ... HTLV-III) with an immunoassay employing a recombinant Escherichia coli-derived viral antigenic peptide." Nature Biotechnology, ... Chang TW and Pan AY, 2008, "Cumulative environmental changes, skewed antigen exposure, and the increase of allergy." Advances ... scientists are able to detect and quantify multiple antigens in one simultaneous attempt. Thereafter, many other types of ...

... htlv-i antigens MeSH D23.050.327.150.510 - htlv-ii antigens MeSH D23.050.327.300 - epstein-barr virus nuclear antigens MeSH ... antigens, cd15 MeSH D23.101.100.900.131 - antigens, cd31 MeSH D23.101.100.920 - antigens, ly MeSH D23.101.100.930 - antigens, ... forssman antigen MeSH D23.050.285.018 - antigens, cd24 MeSH D23.050.285.025 - antigens, cd30 MeSH D23.050.285.040 - antigens, ... hla-a antigens MeSH D23.050.301.500.450.370.372 - hla-a1 antigen MeSH D23.050.301.500.450.370.374 - hla-a2 antigen MeSH D23.050 ...

Dendritic cells are antigen-presenting cells that process antigen material and present it to other T cells. Following the ... Viruses that have been associated with Sjögren's syndrome include human T-lymphotropic virus type 1 (HTLV-1), Epstein-Barr ... Studies on the polymorphisms of human leukocyte antigen (HLA)-DR and HLA-DQ gene regions in Sjögren's patients show ... As with other autoimmune diseases, susceptibility to Sjögren's syndrome is greatly influenced by the human leukocyte antigen. ...

Molecular mimicry refers to an overlap in structural similarity between a viral antigen and a self-antigen. The bystander ... Viruses such as the human papillomavirus (HPV), human T-lymphotropic virus (HTLV) etc., can stimulate growth of tumours in ... Nevertheless, induction of apoptosis in major immune cells or antigen-presenting cells may also act as a mechanism of ... mechanism hypothesizes the initiation of a non-specific and overreactive antiviral response that tackles self-antigens in the ...

The clustering of familial cases has led to the investigation of human leukocyte antigen (HLA) associations. The inciting event ... Infectious causes of intermediate uveitis include Epstein-Barr virus infection, Lyme disease, HTLV-1 virus infection, cat ...

Molecular diagnosis can be based on knowledge of genes encoding the parasite's i-antigen and is performed by PCR and ... HTLV, Covid Taxonomy". Detailed life cycle of Ichthyophthirius multifiliis at MetaPathogen Treatment information for freshwater ... However, several studies have identified potential vaccine candidate proteins, e.g. i-antigens and others, of the parasite, ... "Variation in primary sequence and tandem repeat copy number among i-antigens of Ichthyophthirius multifiliis". Molecular and ...

Other tests are used to look for donors during this period, specifically the p24 antigen test and nucleic acid testing. In ... "HTLV III" Not relevant unless recipient's immune system is compromised (i.e. infants). is Japanese encephalitis a possible TTI ...

HTLV-1 serologies are negative, and serum immunoglobins are within normal limits with no paraproteins present. It is postulated ... and the neoplastic cells are typically positive for pan-T antigens CD2, CD3, and CD7 and negative for TdT and CD1a. The ...

HERV-K env and HERV-H env, considered to be a new class of tumor-associated antigens, have been found to promote strong ... HTLV-1); 2) RNA viruses - influenza A virus, hepatitis C virus (HCV), severe acute respiratory syndrome coronavirus-2 (SARSCoV- ... The potential advantage of this novel approach is that, by using HERV antigens as surrogate markers of HIV-infected cells, it ... As evidence of this, immunization of non-human primates with ERV-derived antigens mounted robust polyfunctional cytotoxic T ...

Certain Human leukocyte antigen class II genes appear more frequently in patients with Kikuchi disease, suggesting that there ... HIV and HTLV-1) in the pathogenesis of KFD. However, many independent studies have failed to identify the presence of these ... Tissue Antigens. 54 (3): 246-253. doi:10.1034/j.1399-0039.1999.540305.x. PMID 10519361. Bosch X, Guilabert A (23 May 2006). " ...

Shuda M, Feng H, Kwun HJ, Rosen ST, Gjoerup O, Moore PS, Chang Y (October 2008). "T antigen mutations are a human tumor- ... Bellon M, Nicot C (2007). "Telomerase: a crucial player in HTLV-I-induced human T-cell leukemia". Cancer Genomics & Proteomics ... Cells such as the macrophage are specialists at this antigen presentation. The production of interferon is an important host ... Vaccines can consist of live-attenuated or killed viruses, viral proteins (antigens), or RNA. Live vaccines contain weakened ...

... and both groups showed HTLV to be the cause. At the same time, a similar HTLV-associated leukemia was identified by the Gallo ... "Spontaneous and antigen-induced production of HIV-inhibitory β-chemokines are associated with AIDS-free status". Proceedings of ... HTLV's role in leukemia was clarified when Kiyoshi Takatsuki and other Japanese researchers, puzzling over an outbreak of a ... 1982 Feb 19;215(4535):975-8 The human type-C retrovirus, HTLV, in Blacks from the Caribbean region, and relationship to adult T ...