"Antibodies to HTLV-III associated antigens in populations exposed to AIDS virus in France". Lancet. 2 (8400): 460. doi:10.1016/ ... HTLV induces the massive proliferation of one or several clones and their cancerization, whereas the other virus, the HIV virus ... For his part, Willy Rozenbaum, warned in private by Leibowitch that an exotic HTLV-type retrovirus could well be the cause of ... The Montagnier team subsequently detected in the cell culture of patient BRU the traces of the first non HTLV retrovirus in ...

The antibody reduces HTLV-1 proviral load and production of proinflammatory cytokines. Valproic acid has also succeeded in ... Blood transfusion products are screened for human T-lymphotropic virus 1 (HTLV-1) antibodies, as a preventive measure. Some of ... "HTLV-1 associated myelopathy/tropical spastic paraparesis , Disease , Overview , Office of Rare Diseases Research (ORDR-NCATS ... "HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP)". Merck Manual Consumer Version. Retrieved 28 February 2023 ...

PMID 6951204.{{cite journal}}: CS1 maint: multiple names: authors list (link) Natural antibodies to human retrovirus HTLV in a ... and both groups showed HTLV to be the cause. At the same time, a similar HTLV-associated leukemia was identified by the Gallo ... HTLV's role in leukemia was clarified when Kiyoshi Takatsuki and other Japanese researchers, puzzling over an outbreak of a ... 1982 Feb 19;215(4535):975-8 The human type-C retrovirus, HTLV, in Blacks from the Caribbean region, and relationship to adult T ...

May 1984). "Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS ... Sarngadharan MG, Popovic M, Bruch L, Schüpbach J, Gallo RC (May 1984). "Antibodies reactive with human T-lymphotropic ... called HTLV-III in the belief that the virus was related to the leukemia viruses of Gallo's earlier work, was the cause of AIDS ... HTLV-III) from patients with AIDS and pre-AIDS". Science. 224 (4648): 497-500. Bibcode:1984Sci...224..497P. doi:10.1126/science ...

"Seroepidemiology of HTLV-III antibody in Danish homosexual men: prevalence, transmission, and disease outcome". BMJ. 289 (6445 ... In his thesis work, entitled "The natural history of HTLV-III infection", from 1986, he described the natural history of HIV ( ... first named HTLV-III) based on studies of homosexual men, hemophiliacs, and African populations. Many of the findings from ... "HTLV-III Seropositivity in European Haemophiliacs Exposed to Factor VIII Concentrate Imported from the USA". The Lancet. 324 ( ...

A patient infected with HTLV can be diagnosed when antibodies against HTLV-1 are detected in the serum. HTLV-1 is a retrovirus ... Seven HTLV-1 genotypes are recognised-HTLV-1a through HTLV-1g. It is estimated that from 10 to 20 million people worldwide are ... HTLV-1 is also associated with a progressive demyelinating upper motor neuron disease known as HTLV-1 associated myelopathy/ ... The term viral tropism refers to which cell types HTLV-I infects. Although HTLV-1 is primarily found in CD4+ T cells, other ...

Voevodin, A. F.; Lapin, B. A.; Yakovleva, L. A.; Ponomaryeva, T. I.; Oganyan, T. E.; Razmadze, E. N. (1985). "Antibodies ... most notably on the identification of the Middle Eastern lineage of human retrovirus HTLV-1, genetic resistance to HIV/AIDS and ... Voevodin, A. F.; Yakovleva, L. A.; Lapin, B. A.; Ponomarjeva, T. I. (1983). "Increased antibody responses to Herpes virus papio ... reacting with human T-lymphotropic retrovirus (HTLV-I) or related antigens in lymphomatous and healthy hamadryas baboons". ...

The Ainu have developed antibodies to HTLV-1, indicating its endemicity to the Ainu and its antiquity in Japan. A subtype "A" ... The Human T cell Lymphotrophic Virus 1 (HTLV-1) is a virus transmitted through exchange of bodily fluids and from mother to ... The HTLV virus genome has been mapped, allowing identification of four major strains and analysis of their antiquity through ...

Anti-MOG antibodies are present in a subgroup of patients with a neuromyelitis optica phenotype. J Neuroinflammation. 2015 Mar ... AIDS-related encephalomyelitis, caused by opportunistic Human T-lymphotropic virus type III (HTLV-III) infection. Chronic ... Histopathology and clinical course of MOG-antibody-associated encephalomyelitis. Annals of Clinical and Translational Neurology ... MD Subacute encephalomyelitis of AIDS and its relation to HTLV‐III infection Neurology April 1987 vol. 37 no. 4 562 doi:10.1212 ...

However, no antibodies were found and so researchers concluded that BLV was not a risk to human health. However, more sensitive ... It is closely related to the human T‑lymphotropic virus type 1 (HTLV-I). BLV may integrate into the genomic DNA of B‑ ... A persistent antibody response can also be detected after experimental infection in deer, rabbits, rats, guinea-pigs, cats, ... One can use the experience with BLV for understanding HTLV-I induced diseases like ATL (adult T-cell leukemia) and HAM/TSP ( ...

By aligning antibodies of distinct specificities in a matrix-like manner, scientists are able to detect and quantify multiple ... HTLV-III) with an immunoassay employing a recombinant Escherichia coli-derived viral antigenic peptide." Nature Biotechnology, ... Chang TW, Kato I, McKinney S, Chanda P, Barone AD, Wong-Staal F, Gallo RC, and Chang NT, 1985, "Detection of antibodies to ... Chu HM, Wright J, Chan YH, Lin CJ, Chang TW & Lim C, 2014, "Two potential therapeutic antibodies bind to a peptide segment of ...

1998). "HLA class I and class II of the Nivkhi, an indigenous population carrying HTLV-I in Sakhalin, Far Eastern Russia". ... Fussell H, Thomas M, Street J, Darke C (1996). "HLA-A9 antibodies and epitopes". Tissue Antigens. 47 (4): 307-12. doi:10.1111/j ...

Viral myelitis Most viral myelitis is acute, but the retroviruses (such as HIV and HTLV) can cause chronic myelitis. ... heterogeneous group of inflammatory spinal cord disorders including autoimmune disorders with known antibodies Myelitis occurs ... HTLV-I/II), syphilis, lyme disease, and tuberculosis can cause myelitis but it can also be caused due to non-infectious or ...

... and HTLV-1 should be tested for and excluded. The differential diagnosis of DILS includes primary Sjogren's Syndrome, IgG4- ... and levels of several autoantibodies including anti-nuclear antibody (ANA), SS-A (Ro), SS-B (La), and rheumatoid factor (RF). ...

Amongst those are the mouse anti rat-TfR antibody OX26 and the rat anti mouse-TfR antibody 8D3. The affinity of the antibody- ... caused by HTLV-1 and the Mantle cell lymphoma (MCL).[citation needed] TfR1 expressed on the endothelial cells of the blood- ... Some of the TfR1 targeting antibodies have been shown to cross the blood-brain barrier, without interfering with the uptake of ... InatherYs, in Évry, France, developed a candidate drug, INA01 antibody (anti-CD71) that showed efficacy in pre-clinical studies ...

Antinuclear antibodies, antiphospholipid antibodies, anti-dsDNA, and rheumatoid factor are usually negative, and may help in ... HIV and HTLV-1) in the pathogenesis of KFD. However, many independent studies have failed to identify the presence of these ... Clinical findings sometimes may include positive results for IgM/IgG/IgA antibodies. For other causes of lymph node enlargement ... In addition, serologic tests including antibodies to a host of viruses have consistently proven noncontributory and no viral ...

When antibodies are bound to its antigens, histamine is released from mast cells and basophils. Either IgE antibodies from the ... HTLV, and Babesia. Transfusion inefficacy or insufficient efficacy of a given unit(s) of blood product, while not itself a " ... A direct antiglobulin test (Coombs test) is also performed as part of the antibody investigation. If there is no antibody ... A positive screen warrants an antibody panel/investigation to determine if it is clinically significant. An antibody panel ...

Finally, antibodies that increase the general activity of T cells appear to be very efficacious in activating antitumoral T ... Human T-lymphotropic virus (HTLV) causes T cell leukemias. Hepatitis B (HBV) and C (HCV) viruses cause chronic inflammation ... These antibodies are often named "checkpoint inhibitors". Using them in cancer patients can lead to important and durable tumor ... Immunostimulatory antibodies increase the activity of T lymphocytes through several mechanisms, including the blockade of ...

Many viruses including herpes simplex virus (HSV), human immunodeficiency virus (HIV) and human T-lymphotropic virus (HTLV) ... they also provide a means by which the virus can escape neutralising antibody. Formation of these synapses has been shown to ... 2005). "Engagement of specific T-cell surface molecules regulates cytoskeletal polarization in HTLV-1-infected lymphocytes". ... "Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton". Science. 299 (5613): 1713-1716. ...

Drugs that are a monoclonal antibody, Monoclonal antibodies, Orphan drugs, All stub articles, Monoclonal antibody stubs, ... Mogamulizumab is being explored as a treatment for HTLV-1-Associated Myelopathy. An early Phase 1-2a study showed decreased in ... which produced antibodies with no fucose in the Fc region. This is thought to enhance its antibody-dependent cell-mediated ... Yu X, Marshall MJ, Cragg MS, Crispin M (June 2017). "Improving Antibody-Based Cancer Therapeutics Through Glycan Engineering" ( ...

HTLV-1) eradicate HTLV-1 in combination with autologous peripheral blood mononuclear cells via antibody-dependent cellular ... Mahieux, R; Gessain, A (2005). "Les nouveaux rétrovirus humains HTLV-3 et HTLV-4" [New human retroviruses: HTLV-3 and HTLV-4] ( ... HTLV-1 and HTLV-2 are both involved in actively spreading epidemics, affecting 15-20 million people worldwide. HTLV-1 is the ... Mahieux, R.; Gessain, Antoine (2009). "The human HTLV-3 and HTLV-4 retroviruses: New members of the HTLV family". Pathologie ...

... hiv antibodies MeSH D12.776.124.486.485.114.254.150.500 - htlv-i antibodies MeSH D12.776.124.486.485.114.254.150.510 - htlv-ii ... hiv antibodies MeSH D12.776.124.790.651.114.254.150.500 - htlv-i antibodies MeSH D12.776.124.790.651.114.254.150.510 - htlv-ii ... antibodies MeSH D12.776.124.486.485.114.071 - antibodies, anti-idiotypic MeSH D12.776.124.486.485.114.089 - antibodies, ... antibodies, bispecific MeSH D12.776.124.486.485.114.143 - antibodies, blocking MeSH D12.776.124.486.485.114.167 - antibodies, ...

Blood tests can be done to determine if a patient has high levels of antibodies that are indicative of the condition, such as ... Viruses that have been associated with Sjögren's syndrome include human T-lymphotropic virus type 1 (HTLV-1), Epstein-Barr ... Among the complications discussed above, women with anti-Ro/SS-A and anti-La/SS-B antibodies who become pregnant have an ... Association between HLA and SS is restricted to patients with anti-SSA/Ro or anti-SSB/La antibodies. Seropositivity for anti-Ro ...

... tropical spastic paraparesis and HTLV-1 associated myelopathy. In HTLV-1 myelopathy, Tax, transactivator expressed by HTLV-1, ... 2004). Catalogue# CPCA-a-Int: Chicken Polyclonal Antibody to alpha-internexin. EnCor Biotechnology Inc. 2011. Duprey, P and D. ...

... monoclonal antibody - monoclonal antibody 3F8 - monocyte - Montanide ISA-51 - Morinda citrifolia - morphology - motexafin ... HTLV-1 - hu14.18-interleukin-2 fusion protein - Huang Lian - human epidermal growth factor receptor 2 - human leukocyte antigen ... bispecific antibody - bispecific monoclonal antibody - bisphosphonate - bizelesin - BL22 immunotoxin - black cohosh - black ... antibody - antibody therapy - anticachexia - anticancer antibiotic - anticarcinogenic - anticoagulant - anticonvulsant - ...

Viruses such as the human papillomavirus (HPV), human T-lymphotropic virus (HTLV) etc., can stimulate growth of tumours in ... Specifically, immunopathology is caused by the excessive release of antibodies, interferons and pro-inflammatory cytokines, ... infected hosts, either by disrupting tumour suppressor gene expression (HPV) or upregulating proto-oncogene expression (HTLV). ...

"tax - Protein Tax-2 - Human T-cell leukemia virus 2 (HTLV-2) - tax gene & protein". www.uniprot.org. Retrieved 2020-05-03. " ... April 2014). "Human cell growth regulator Ly-1 antibody reactive homologue accelerates processing of preribosomal RNA". Genes ...

Antibody microarrays use antibodies as probes and antigens as targets. They can be used to directly measure the antigen ... CMV infection provoked a unique interferon response whereas HTLV-1 infection induced NF-kB target genes. A type of white blood ... Epitope mapping identifies the sites of antibodies to which their target antigens bind. In the past, scientists would have to ... Peptide microarrays use antigen peptides as probes and serum antibodies as targets. These can be used for functional immunomic ...

HTLV-III) from patients with AIDS and at risk for AIDS". Science. 224 (4648): 500-503. Bibcode:1984Sci...224..500G. doi:10.1126 ... "Antibodies to the core protein of lymphadenopathy-associated virus (LAV) in patients with AIDS". Science. 225 (4659): 321-323. ... they concluded the agent causing this new disease may be a retrovirus but it was not HTLV, the only known retrovirus at the ...

From rare viruses such as HTLV to more common infections such as hepatitis A, every sexually transmitted infection that entered ... were to become invaluable measures of the rise of HIV infection once a test for HIV antibodies became available in the mid- ...