... , GFAP - 137780 Harrison BC, Mobley PL (January 1992). "Phosphorylation of glial fibrillary ... Glial fibrillary acidic protein (GFAP) is a protein that is encoded by the GFAP gene in humans. It is a type III intermediate ... "A new splice variant of glial fibrillary acidic protein, GFAP epsilon, interacts with the presenilin proteins". The Journal of ... Glial fibrillary acidic protein has been shown to interact with MEN1 and PSEN1. Although GFAP alpha is the only isoform which ...
Shan F, Long Y, Qiu W. Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy: A Review of the Literature. Front Immunol. ... doi:10.1001/jamaneurol.2016.2549 Y. Long et al., Autoimmune glial fibrillary acidic protein astrocytopathy in Chinese patients ... Boyan Fang el al., Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy. A Novel Meningoencephalomyelitis, November 2016, ... in which the immune system of the patient attacks a protein of the nervous system called glial fibrillary acidic protein (GFAP ...
Positive: Glial fibrillary acidic protein (GFAP), pancytokeratin, and S100 protein. Smooth muscle actin may be positive in ...
... like increased protein carbonylation and high levels of Glial fibrillary acidic protein (GFAP), which in NAGM areas comes ... Nicholas AP, Sambandam T, Echols JD, Tourtellotte WW (2004). "Increased citrullinated glial fibrillary acidic protein in ... hematoxylin and eosin or immunohistochemistry for glial fibrillary acidic protein) and stains for the different lymphocyte ... They are named glial scars because they are produced by glial cells, mainly astrocytes, and their presence prevents ...
The cytoplasm of gemistocytes stains positive for glial fibrillary acidic protein, GFAP. While the intermediate filaments in ... Gliosis occurs when the body creates more, or larger, glial cells that cause scars in the brain that impact body functions. The ... Many gliomas exhibit cells that do not exist in normal brain tissue and are not seen in glial differentiation. Of these gliomas ... Rapid progression of neoplastic glial cells are able to outgrow the vascular supply of the tumor which results in a metabolic ...
Glial fibrillary acidic protein (GFAP) is found in astrocytes and other glia. Peripherin found in peripheral neurons. Vimentin ... "Protective role of phosphorylation in turnover of glial fibrillary acidic protein in mice". The Journal of Neuroscience. 22 (16 ... There are four proteins classed as type III intermediate filament proteins, which may form homo- or heteropolymeric proteins. ... Regardless of the group, keratins are either acidic or basic. Acidic and basic keratins bind each other to form acidic-basic ...
PaSCs express the intermediate filament proteins desmin and glial fibrillary acidic protein. The expression of a diverse range ... Protein kinases such as MAPKs are primary mediators of activating signals initiated by the growth factors, angiotensin II and ... The up regulation of matri-cellular proteins such as galectin-1, and tenascin-C is present in the stromal tissues of pancreatic ... Matri-cellular proteins may therefore directly contribute to the development of pancreatic cancer through stimulating cancer ...
"Domain-specific phosphorylation of vimentin and glial fibrillary acidic protein by PKN". Biochem. Biophys. Res. Commun. 234 (3 ... "Domain-specific phosphorylation of vimentin and glial fibrillary acidic protein by PKN". Biochem. Biophys. Res. Commun. 234 (3 ... Serine/threonine-protein kinase N1 is an enzyme that in humans is encoded by the PKN1 gene. The protein encoded by this gene ... "Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the ...
... glial fibrillary acidic protein), cytokeratin, vimentin and fibronectin. S-100 protein and GFAP expression seem to be strongest ... Velasco, M. E.; Roessmann, U.; Gambetti, P. (March 1982). "The presence of glial fibrillary acidic protein in the human ... The first marker protein discovered in FS cells was S-100b, which is a calcium-binding protein expressed by glial cells. Some ... The protein Annexin A1 (ANXA1), found in high quantities in the anterior pituitary gland, is located specifically in the ...
May 1997). "Domain-specific phosphorylation of vimentin and glial fibrillary acidic protein by PKN". Biochemical and ... "Menin's interaction with glial fibrillary acidic protein and vimentin suggests a role for the intermediate filament network in ... Vimentin is a type III intermediate filament (IF) protein that is expressed in mesenchymal cells. IF proteins are found in all ... Herrmann H, Wiche G (January 1987). "Plectin and IFAP-300K are homologous proteins binding to microtubule-associated proteins 1 ...
Seay M, Galetta S (September 2018). "Glial Fibrillary Acidic Protein Antibody: Another Antibody in the Multiple Sclerosis ... Some cases of CIDP are reported to be produced by auto-antibodies against several neurofascin proteins. These proteins are ... contactin associated protein 1 (CASPR1) and gliomedin. All of them nodal and paranodal proteins. Several anti-TNF drugs like ... in MS-like and ADEM-like Proteomic analysis have shown that two proteins, Secretogranin II and Protein 7B2, in CSF can be used ...
His laboratory first sequenced GFAP (glial fibrillary acidic protein), and helped to elucidate its role in neural structure and ... 1990). "Characterization of human cDNA and genomic clones for glial fibrillary acidic protein". Molecular Brain Research. 7 (4 ...
"Antisense suppression of glial fibrillary acidic protein as a treatment for Alexander disease". Annals of Neurology. 83 (1): 27 ... "Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease". Nature. 585 (7825): 397-403. Bibcode:2020Natur.585.. ...
... encoding glial fibrillary acidic protein, are associated with Alexander disease". Nature Genetics. 27 (1): 117-20. doi:10.1038/ ... The NDUFV1 gene produces a 50.8 kDa protein composed of 464 amino acids. NDUFV1, the protein encoded by this gene, is a member ... NDUFV1 has been shown to have 103 binary protein-protein interactions including 97 co-complex interactions. NDUFV1 appears to ... "Cardiac Organellar Protein Atlas Knowledgebase (COPaKB) -- Protein Information". amino.heartproteome.org. Retrieved 2018-08-27 ...
Type III contains the proteins vimentin, desmin, peripherin and glial fibrillary acidic protein (GFAP). Type IV consists of the ... The triplet proteins are named based upon their relative size (low, medium, high). The apparent molecular mass of each protein ... The proteins that form neurofilaments are members of the intermediate filament protein family, which is divided into six types ... This is due to the anomalous electrophoretic migration of these proteins and is particularly extreme for neurofilament proteins ...
It works by targeting stem cells using glial fibrillary acidic proteins and nestin expression. These targeted stem cells ... The protein nestin is an intermediate filament, which is essential for the radial growth of axons, and is therefore used to ... Radial glial cells extend processes from their soma in the avian ventricular zone to the parenchyma of the adult forebrain. ... Cre protein is also commonly used in targeting stem cells that will undergo gene changes upon treatment with tamoxifen. ...
The sustentacular cells are S-100 positive and focally positive for glial fibrillary acidic protein. By histochemistry, the ...
Immunoglobulins directed against the α-isoform of glial fibrillary acidic protein (GFAP-IgG) predicted a special ... "Glial fibrillary acidic protein IgG related myelitis: characterisation and comparison with aquaporin-4-IgG myelitis". J. Neurol ...
Like astrocytes, their cytoplasm presents specific intermediate filaments made up of glial fibrillary acidic protein (GFAP). ... Pituicytes are glial cells of the posterior pituitary. Their main role is to assist in the storage and release of ... Pituicytes have an irregular and branched shape which resembles that of another type of glial cell: the astrocyte. ... Pituicytes are similar to astrocytes, another type of glial cell. Their main role is to assist in the storage and release of ...
"A new splice variant of glial fibrillary acidic protein, GFAP epsilon, interacts with the presenilin proteins". J. Biol. Chem. ... Levesque G (1999). "Presenilins interact with armadillo proteins including neural-specific plakophilin-related protein and beta ... They found that there is higher level expression of both proteins and a multidrug resistance-associated protein 1 (ABCC1) was ... Presenilin-1 (PS-1) is a presenilin protein that in humans is encoded by the PSEN1 gene. Presenilin-1 is one of the four core ...
... regulates Glial fibrillary acidic protein and YKL-40 in astrocytes. Nfix has been shown to interact with SKI protein and it is ... "Nuclear factor-1-X regulates astrocyte-specific expression of the alpha1-antichymotrypsin and glial fibrillary acidic protein ... NFIX+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text ... Nuclear factor 1 X-type is a protein that in humans is encoded by the NFIX gene. NFI-X3, a splice variant of NFIX, ...
Up to 20% of choroid plexus papilloma patients may test positive for glial fibrillary acidic protein (GFAP). Studies have found ... In people with choroid plexus tumors, complexes formed by the big T antigen and the tumor suppressor proteins p53 and pRb have ... These cancers rarely exhibit nuclear p53 protein positivity. Aicardi syndrome, hypomelanosis of Ito, and 9p duplication are ...
This mouse also shows a genetic tendency for glial fibrillary acidic protein in their lens epithelial cells. This is a new ... "Recent evolutionary origin of the expression of the glial fibrillary acidic protein (GFAP) in lens epithelial cells. A ...
The cells were not immunoreactive for neurofilament, neuron-specific enolase (NSE), and glial fibrillary acidic protein (GFAP ... Before implantation, the NSCs were treated with neurogenin 2 protein to encourage the proliferation of the intended inner ear ...
Quiescent Oct4 + Neural Stem Cells (NSCs) Repopulate Ablated Glial Fibrillary Acidic Protein + NSCs in the Adult Mouse Brain. ... Repopulate Ablated Glial Fibrillary Acidic Protein+NSCs in the Adult Mouse Brain". Stem Cells. 35 (9): 2071-2082. doi:10.1002/ ...
Garrison CJ, Dougherty PM, Kajander KC, Carlton SM (November 1991). "Staining of glial fibrillary acidic protein (GFAP) in ... many of these cells express the intermediate filament glial fibrillary acidic protein (GFAP). Several forms of astrocytes exist ... A recent study has shown that levels of glial proteins, and NOT neuronal proteins, are most abnormal in Alzheimer's disease. ... astrocytes were generated by exposing human glial precursor cells to bone morphogenetic protein (bone morphogenetic protein is ...
Symptoms result from the accumulation of Glial fibrillary acidic protein (GFAP) as the result of a mutation in the GFAP gene, ... Hol, Elly M.; Pekny, Milos (February 2015). "Glial fibrillary acidic protein (GFAP) and the astrocyte intermediate filament ... As myelin is produced by oligodendrocytes (a type of glial cell) in the central nervous system, an easy place to look for the ... Intermediate filaments are proteins responsible for the makeup of the cellular cytoskeleton; thus, this type of mutation causes ...
... and increase synthesis of glial fibrillary acidic protein (GFAP). GFAP is an important intermediate filament protein that ... CDK is a cell-cycle promoting protein, which along with other pro-growth proteins is abnormally activated during glial scar ... Subsequent analysis showed a marked reduction in glial scarring. Particularly, extracellular matrix protein deposition (laminin ... Chondroitinase ABC has been shown to degrade glial scars. Degrading the glial scar with chondroitinase has been shown to ...
... identifying regulator proteins like glial fibrillary acidic protein. In collaboration with neuroscientist David Sulzer of ... Cuervo, A. M.; Dice, J. F. (1996-07-26). "A receptor for the selective uptake and degradation of proteins by lysosomes". ... In 1996 and 2000, Cuervo and Dice published their findings on this pathway, identified the lysosomal membrane protein LAMP2A as ... Cuervo's research team also identified LRRK2, a protein enzyme that becomes mutated in Parkinson's disease, disrupts the ...
The most widely accepted model of an adult NSC is a radial, glial fibrillary acidic protein-positive cell. Quiescent stem cells ... Because FOX proteins regulate neural stem cell homeostasis, FOX proteins have been used to protect neural stem cells by ... NSCs transition into radial glial cells (RGCs) also known as radial glial progenitor cells, (RGPs) and reside in a transient ... Neural stem cells are more specialized than ESCs because they only generate radial glial cells that give rise to the neurons ...