Flavoprotein
The flavoproteins are some of the most-studied families of enzymes. Flavoproteins have either FMN (flavin mononucleotide) or ... Flavoproteins are mainly located in the mitochondria. Of all flavoproteins, 90% perform redox reactions and the other 10% are ... Flavoproteins are proteins that contain a nucleic acid derivative of riboflavin. These proteins are involved in a wide array of ... Flavoproteins were first mentioned in 1879, when they isolated as a bright-yellow pigment from cow's milk. They were initially ...
Electron-transferring flavoprotein
An electron transfer flavoprotein (ETF) or electron transfer flavoprotein complex (CETF) is a flavoprotein located on the ... Pfam entry for Electron transfer flavoprotein domain Pfam entry for Electron transfer flavoprotein FAD-binding domain (Proteins ... Roberts DL, Frerman FE, Kim JJ (1996). "Three-dimensional structure of human electron transfer flavoprotein to 2.1-A resolution ... Tsai MH, Saier MH (1995). "Phylogenetic characterization of the ubiquitous electron transfer flavoprotein families ETF-alpha ...
Electron-transferring-flavoprotein dehydrogenase
... (ETF dehydrogenase or electron transfer flavoprotein-ubiquinone oxidoreductase ... Ramsay RR, Steenkamp DJ, Husain M (Feb 1987). "Reactions of electron-transfer flavoprotein and electron-transfer flavoprotein: ... Beckmann JD, Frerman FE (Jul 1985). "Reaction of electron-transfer flavoprotein with electron-transfer flavoprotein-ubiquinone ... Frerman, F. E.; Goodman, S. I. (1985). "Deficiency of Electron Transfer Flavoprotein or Electron Transfer Flavoprotein: ...
Flavoprotein pyridine nucleotide cytochrome reductases
... nitrate reductase and its relationship to the sequences of other flavoprotein oxidoreductases. A family of flavoprotein ... Flavoprotein pyridine nucleotide cytochrome reductases catalyse the interchange of reducing equivalents between one-electron ... Siegel LM, Ostrowski J, Rueger DC, Miller BE, Kredich NM, Barber MJ (1989). "Characterization of the flavoprotein moieties of ... Karplus PA, Bruns CM, Correll CC, Ludwig ML (1993). "Structural prototypes for an extended family of flavoprotein reductases: ...
Isoalloxazine
Luliano, James N. (2019). "Vibrational spectroscopy of flavoproteins". New Approaches for Flavin Catalysis. Methods in ...
Martha L. Ludwig
... focusing on studying flavoproteins. Ludwig focused on studying flavodoxin in her laboratory. In 1969, Ludwig had her first ... the first flavoprotein structure, iron-superoxide dismutase, p-hydroxybenzoate hydroxylase and phthalate dioxygenase reductase ...
1-Pyrroline-5-carboxylic acid
Flavoproteins: Beyond the Classical Paradigms. 632: 142-157. doi:10.1016/j.abb.2017.07.005. ISSN 0003-9861. PMC 5650515. PMID ...
Mixed-function oxidase
Most of the oxidases are flavoproteins. The name "mixed-function oxidase" indicates that the enzyme oxidizes two different ...
FAD-dependent urate hydroxylase
These FAD-dependent urate hydroxylases are flavoproteins. This enzyme catalyses the following chemical reaction urate + FADH + ... a non-homologous isofunctional isoform of the flavoprotein urate hydroxylase HpxO". Environmental Microbiology Reports. 4 (6): ...
Glutamate synthase (NADPH)
An iron-sulfide flavoprotein". J. Biol. Chem. 247 (22): 7407-19. PMID 4565085. Tempest DW, Meers JL, Brown CM (1970). " ... Portal: Biology v t e (EC 1.4.1, NADPH-dependent enzymes, Flavoproteins, Iron enzymes, Sulfur enzymes, Iron-sulfur enzymes, ...
L-ornithine N5 monooxygenase
In A. fumigatus, it is classified as a flavoprotein because FAD is a cofactor. It catalyzes the FAD and NADPH-dependent ... Paul CE, Eggerichs D, Westphal AH, Tischler D, van Berkel WJ (November 2021). "Flavoprotein monooxygenases: Versatile ...
L-amino-acid oxidase
Meister A, Wellner D (1963). "Flavoprotein amino acid oxidase". In Boyer PD, Lardy H, Myrbäck K (eds.). The Enzymes. Vol. 7 ( ... Flavoproteins, Enzymes of known structure, Hydrogen peroxide). ...
Vincent Massey (enzymologist)
His thesis project revolved around the enzyme fumarase (not a flavoprotein), for example a study of the effects of temperature ... This started Massey's career on flavins and flavoproteins. In 1957, Massey returned to England to be a lecturer at the ... Ghisla, S; Massey, V (1986). "New flavins for old - artificial flavins as active-site probes of flavoproteins". Biochem. J. 239 ...
D-amino acid oxidase
This enzyme is a flavoprotein belonging to the FAD dependent oxidoreductase family, and acts on the CH-NH2 group of D-amino ... These are all typical properties associated with flavoproteins. Human DAAO has slightly different properties from other DAAO ...
Murburn concept
e.g. hemeproteins, flavoproteins,Cu/Zn proteins, etc.). Occasionally, some proteins that lack the above cofactors but have high ...
Flavin adenine dinucleotide
Flavoproteins are mainly located in the mitochondria because of their redox power. Of all flavoproteins, 90% perform redox ... Due to the importance of flavoproteins, it is unsurprising that approximately 60% of human flavoproteins cause human disease ... A flavoprotein is a protein that contains a flavin group, which may be in the form of FAD or flavin mononucleotide (FMN). Many ... Flavoproteins have either an FMN or FAD molecule as a prosthetic group, this prosthetic group can be tightly bound or ...
Thioredoxin reductase
Both classes are flavoproteins which function as homodimers. Each monomer contains a FAD prosthetic group, a NADPH binding ...
Flavin reductase
Ceccoli RD, Bianchi DA, Rial DV (6 Feb 2014). "Flavoprotein monooxegenases for oxidative biocatalysis". Front Microbiol. 5: 25 ...
Glycine oxidase
Characterization of a new flavoprotein". The Journal of Biological Chemistry. 277 (9): 6985-93. doi:10.1074/jbc.M111095200. ...
Flavin group
It is in one or the other of these forms that flavin is present as a prosthetic group in flavoproteins. The flavin group is ... "Light-mediated reduction of flavoproteins with flavins as catalysts". Biochemistry. 17 (1): 1-8. doi:10.1021/bi00594a001. PMID ...
Photolyase
... s are flavoproteins and contain two light-harvesting cofactors. Many photolyases have an N-terminal domain that binds ...
Methionine synthase) reductase
Olteanu H, Banerjee R (2001). "Human methionine synthase reductase, a soluble P-450 reductase-like dual flavoprotein, is ... The enzyme employs one coenzyme, flavoprotein. MTRR works by catalyzing the following chemical reaction: 2 [methionine synthase ... a flavoprotein defective in patients with homocystinuria". Proceedings of the National Academy of Sciences. 95 (6): 3059-3064. ...
Oxalate oxidase
Portal: Biology v t e (EC 1.2.3, Flavoproteins, Manganese enzymes, Enzymes of known structure, All stub articles, EC 1.2 stubs) ... DATTA PK, MEEUSE BJ (1955). "Moss oxalic acid oxidase-a flavoprotein". Biochim. Biophys. Acta. 17 (4): 602-3. doi:10.1016/0006- ...
Trimethylamine dehydrogenase
Huang L, Rohlfs RJ, Hille R (1995). "The reaction of trimethylamine dehydrogenase with electron transferring flavoprotein". J. ... The systematic name of this enzyme class is trimethylamine:electron-transferring flavoprotein oxidoreductase (demethylating). ... Scrutton NS, Sutcliffe MJ (2000). "Trimethylamine dehydrogenase and electron transferring flavoprotein". Subcell. Biochem. 35: ... reduced electron-transferring flavoprotein The 3 substrates of this enzyme are trimethylamine, H2O, and electron-transferring ...
Cluster of Excellence Frankfurt Macromolecular Complexes
To manipulate a protein photocycle in a directed manner, CEF groups collaborated to modify the flavoprotein dodecin at its key ... "Directed manipulation of a flavoprotein photocycle". Angewandte Chemie International Edition. 52 (32): 8463-6. doi:10.1002/anie ...
Apoptosis-inducing factor
Apoptosis inducing factor is a flavoprotein. It also acts as an NADH oxidase. Another AIF function is to regulate the ...
Sarcosine dehydrogenase
Sato M, Ohishi N, Yagi K (April 1979). "Identification of a covalently bound flavoprotein in rat liver mitochondria with ... Roth JP, Klinman JP (January 2003). "Catalysis of electron transfer during activation of O2 by the flavoprotein glucose oxidase ... Sarcosine dehydrogenase is linked by electron-transferring flavoprotein (ETF) to the respiratory redox chain. The general ... Portal: Biology (EC 1.5.8, Flavoproteins, Enzymes of unknown structure). ...
Arginine 2-monooxygenase
doi:10.1016/0006-3002(62)90632-7. Portal: Biology (EC 1.13.12, Flavoproteins, Enzymes of unknown structure). ...
MTRR (gene)
Flavin adenine dinucleotide in its oxidized form, FAD is a cofactor of flavoprotein oxidoreductase enzymes. Flavoprotein ... Interacts with the cofactor or prosthetic group, FAD of flavoproteins and contains a flavin moiety in the form of FAD or FMN ( ... Flavoproteins are ubiquitous biocatalysts binding specific redox active prosthetic groups. The domain is associated with ... a flavoprotein defective in patients with homocystinuria". Proceedings of the National Academy of Sciences of the United States ...
Glucose-methanol-choline oxidoreductase family
The glucose-methanol-choline (GMC) oxidoreductases are FAD flavoproteins oxidoreductases. These enzymes include a variety of ...